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| Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 期刊论文
Science, 2021
作者: Nir Drayman; Jennifer K. DeMarco; Krysten A. Jones; Saara-Anne Azizi; Heather M. Froggatt; Kemin Tan; Natalia Ivanovna Maltseva; Siquan Chen; Vlad Nicolaescu; Steve Dvorkin; Kevin Furlong; Rahul S. Kathayat; Mason R. Firpo; Vincent Mastrodomenico; Emily A. Bruce; Madaline M. Schmidt; Robert Jedrzejczak; Miguel Á. Muñoz-Alía; Brooke Schuster; Vishnu Nair; Kyu-yeon Han; Amornrat O’Brien; Anastasia Tomatsidou; Bjoern Meyer; Marco Vignuzzi; Dominique Missiakas; Jason W. Botten; Christopher B. Brooke; Hyun Lee; Susan C. Baker; Bryan C. Mounce; Nicholas S. Heaton; William E. Severson; Kenneth E. Palmer; Bryan C. Dickinson; Andrzej Joachimiak; Glenn Randall; Savaş Tay
  收藏 | 浏览/下载：13/0 | 提交时间：2021/08/25 |
| Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity 期刊论文
Science, 2021
作者: Parsa Akbari; Ankit Gilani; Olukayode Sosina; Jack A. Kosmicki; Lori Khrimian; Yi-Ya Fang; Trikaldarshi Persaud; Victor Garcia; Dylan Sun; Alexander Li; Joelle Mbatchou; Adam E. Locke; Christian Benner; Niek Verweij; Nan Lin; Sakib Hossain; Kevin Agostinucci; Jonathan V. Pascale; Ercument Dirice; Michael Dunn; Regeneron Genetics Center‡; DiscovEHR Collaboration‡; William E. Kraus; Svati H. Shah; Yii-Der I. Chen; Jerome I. Rotter; Daniel J. Rader; Olle Melander; Christopher D. Still; Tooraj Mirshahi; David J. Carey; Jaime Berumen-Campos; Pablo Kuri-Morales; Jesus Alegre-Díaz; Jason M. Torres; Jonathan R. Emberson; Rory Collins; Suganthi Balasubramanian; Alicia Hawes; Marcus Jones; Brian Zambrowicz; Andrew J. Murphy; Charles Paulding; Giovanni Coppola; John D. Overton; Jeffrey G. Reid; Alan R. Shuldiner; Michael Cantor; Hyun M. Kang; Goncalo R. Abecasis; Katia Karalis; Aris N. Economides; Jonathan Marchini; George D. Yancopoulos; Mark W. Sleeman; Judith Altarejos; Giusy Della Gatta; Roberto Tapia-Conyer; Michal L. Schwartzman; Aris Baras; Manuel A. R. Ferreira; Luca A. Lotta
收藏 | 浏览/下载：28/0 | 提交时间：2021/07/27 |
| In situ genome sequencing resolves DNA sequence and structure in intact biological samples 期刊论文
Science, 2021
作者: Andrew C. Payne; Zachary D. Chiang; Paul L. Reginato; Sarah M. Mangiameli; Evan M. Murray; Chun-Chen Yao; Styliani Markoulaki; Andrew S. Earl; Ajay S. Labade; Rudolf Jaenisch; George M. Church; Edward S. Boyden; Jason D. Buenrostro; Fei Chen
收藏 | 浏览/下载：11/0 | 提交时间：2021/03/02 |
| Core commitments for field trials of gene drive organisms 期刊论文
Science, 2020
作者: Kanya C. Long; Luke Alphey; George J. Annas; Cinnamon S. Bloss; Karl J. Campbell; Jackson Champer; Chun-Hong Chen; Amit Choudhary; George M. Church; James P. Collins; Kimberly L. Cooper; Jason A. Delborne; Owain R. Edwards; Claudia I. Emerson; Kevin Esvelt; Sam Weiss Evans; Robert M. Friedman; Valentino M. Gantz; Fred Gould; Sarah Hartley; Elizabeth Heitman; Janet Hemingway; Hirotaka Kanuka; Jennifer Kuzma; James V. Lavery; Yoosook Lee; Marce Lorenzen; Jeantine E. Lunshof; John M. Marshall; Philipp W. Messer; Craig Montell; Kenneth A. Oye; Megan J. Palmer; Philippos Aris Papathanos; Prasad N. Paradkar; Antoinette J. Piaggio; Jason L. Rasgon; Gordana Rašić; Larisa Rudenko; J. Royden Saah; Maxwell J. Scott; Jolene T. Sutton; Adam E. Vorsino; Omar S. Akbari
收藏 | 浏览/下载：23/0 | 提交时间：2020/12/22 |
| Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms 期刊论文
Science, 2020
作者: M. Alejandra Tortorici; Martina Beltramello; Florian A. Lempp; Dora Pinto; Ha V. Dang; Laura E. Rosen; Matthew McCallum; John Bowen; Andrea Minola; Stefano Jaconi; Fabrizia Zatta; Anna De Marco; Barbara Guarino; Siro Bianchi; Elvin J. Lauron; Heather Tucker; Jiayi Zhou; Alessia Peter; Colin Havenar-Daughton; Jason A. Wojcechowskyj; James Brett Case; Rita E. Chen; Hannah Kaiser; Martin Montiel-Ruiz; Marcel Meury; Nadine Czudnochowski; Roberto Spreafico; Josh Dillen; Cindy Ng; Nicole Sprugasci; Katja Culap; Fabio Benigni; Rana Abdelnabi; Shi-Yan Caroline Foo; Michael A. Schmid; Elisabetta Cameroni; Agostino Riva; Arianna Gabrieli; Massimo Galli; Matteo S. Pizzuto; Johan Neyts; Michael S. Diamond; Herbert W. Virgin; Gyorgy Snell; Davide Corti; Katja Fink; David Veesler
收藏 | 浏览/下载：19/0 | 提交时间：2020/11/24 |
| An orally available non-nucleotide STING agonist with antitumor activity 期刊论文
Science, 2020
作者: Bo-Sheng Pan; Samanthi A. Perera; Jennifer A. Piesvaux; Jeremy P. Presland; Gottfried K. Schroeder; Jared N. Cumming; B. Wesley Trotter; Michael D. Altman; Alexei V. Buevich; Brandon Cash; Saso Cemerski; Wonsuk Chang; Yiping Chen; Peter J. Dandliker; Guo Feng; Andrew Haidle; Timothy Henderson; James Jewell; Ilona Kariv; Ian Knemeyer; Johnny Kopinja; Brian M. Lacey; Jason Laskey; Charles A. Lesburg; Rui Liang; Brian J. Long; Min Lu; Yanhong Ma; Ellen C. Minnihan; Greg O’Donnell; Ryan Otte; Laura Price; Larissa Rakhilina; Berengere Sauvagnat; Sharad Sharma; Sriram Tyagarajan; Hyun Woo; Daniel F. Wyss; Serena Xu; David Jonathan Bennett; George H. Addona
收藏 | 浏览/下载：14/0 | 提交时间：2020/08/25 |
| DNA vaccine protection against SARS-CoV-2 in rhesus macaques 期刊论文
Science, 2020
作者: Jingyou Yu; Lisa H. Tostanoski; Lauren Peter; Noe B. Mercado; Katherine McMahan; Shant H. Mahrokhian; Joseph P. Nkolola; Jinyan Liu; Zhenfeng Li; Abishek Chandrashekar; David R. Martinez; Carolin Loos; Caroline Atyeo; Stephanie Fischinger; John S. Burke; Matthew D. Slein; Yuezhou Chen; Adam Zuiani; Felipe J. N. Lelis; Meghan Travers; Shaghayegh Habibi; Laurent Pessaint; Alex Van Ry; Kelvin Blade; Renita Brown; Anthony Cook; Brad Finneyfrock; Alan Dodson; Elyse Teow; Jason Velasco; Roland Zahn; Frank Wegmann; Esther A. Bondzie; Gabriel Dagotto; Makda S. Gebre; Xuan He; Catherine Jacob-Dolan; Marinela Kirilova; Nicole Kordana; Zijin Lin; Lori F. Maxfield; Felix Nampanya; Ramya Nityanandam; John D. Ventura; Huahua Wan; Yongfei Cai; Bing Chen; Aaron G. Schmidt; Duane R. Wesemann; Ralph S. Baric; Galit Alter; Hanne Andersen; Mark G. Lewis; Dan H. Barouch
收藏 | 浏览/下载：18/0 | 提交时间：2020/08/18 |
| Autoreactivity in naïve human fetal B cells is associated with commensal bacteria recognition 期刊论文
Science, 2020
作者: Jeff W. Chen; Tyler A. Rice; Jason M. Bannock; Agata A. Bielecka; Juliet D. Strauss; Jason R. Catanzaro; Haowei Wang; Laurence C. Menard; Jennifer H. Anolik; Noah W. Palm; Eric Meffre
收藏 | 浏览/下载：6/0 | 提交时间：2020/07/21 |
| HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease 期刊论文
Science, 2020
作者: Sarah A. Cook; William A. Comrie; M. Cecilia Poli; Morgan Similuk; Andrew J. Oler; Aiman J. Faruqi; Douglas B. Kuhns; Sheng Yang; Alexander Vargas-Hernández; Alexandre F. Carisey; Benjamin Fournier; D. Eric Anderson; Susan Price; Margery Smelkinson; Wadih Abou Chahla; Lisa R. Forbes; Emily M. Mace; Tram N. Cao; Zeynep H. Coban-Akdemir; Shalini N. Jhangiani; Donna M. Muzny; Richard A. Gibbs; James R. Lupski; Jordan S. Orange; Geoffrey D. E. Cuvelier; Moza Al Hassani; Nawal Al Kaabi; Zain Al Yafei; Soma Jyonouchi; Nikita Raje; Jason W. Caldwell; Yanping Huang; Janis K. Burkhardt; Sylvain Latour; Baoyu Chen; Gehad ElGhazali; V. Koneti Rao; Ivan K. Chinn; Michael J. Lenardo
收藏 | 浏览/下载：12/0 | 提交时间：2020/07/14 |
| DNA-directed nanofabrication of high-performance carbon nanotube field-effect transistors 期刊论文
Science, 2020
作者: Mengyu Zhao; Yahong Chen; Kexin Wang; Zhaoxuan Zhang; Jason K. Streit; Jeffrey A. Fagan; Jianshi Tang; Ming Zheng; Chaoyong Yang; Zhi Zhu; Wei Sun
收藏 | 浏览/下载：7/0 | 提交时间：2020/05/25 |
