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Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity 期刊论文
Science, 2021
作者:  Parsa Akbari;  Ankit Gilani;  Olukayode Sosina;  Jack A. Kosmicki;  Lori Khrimian;  Yi-Ya Fang;  Trikaldarshi Persaud;  Victor Garcia;  Dylan Sun;  Alexander Li;  Joelle Mbatchou;  Adam E. Locke;  Christian Benner;  Niek Verweij;  Nan Lin;  Sakib Hossain;  Kevin Agostinucci;  Jonathan V. Pascale;  Ercument Dirice;  Michael Dunn;  Regeneron Genetics Center‡;  DiscovEHR Collaboration‡;  William E. Kraus;  Svati H. Shah;  Yii-Der I. Chen;  Jerome I. Rotter;  Daniel J. Rader;  Olle Melander;  Christopher D. Still;  Tooraj Mirshahi;  David J. Carey;  Jaime Berumen-Campos;  Pablo Kuri-Morales;  Jesus Alegre-Díaz;  Jason M. Torres;  Jonathan R. Emberson;  Rory Collins;  Suganthi Balasubramanian;  Alicia Hawes;  Marcus Jones;  Brian Zambrowicz;  Andrew J. Murphy;  Charles Paulding;  Giovanni Coppola;  John D. Overton;  Jeffrey G. Reid;  Alan R. Shuldiner;  Michael Cantor;  Hyun M. Kang;  Goncalo R. Abecasis;  Katia Karalis;  Aris N. Economides;  Jonathan Marchini;  George D. Yancopoulos;  Mark W. Sleeman;  Judith Altarejos;  Giusy Della Gatta;  Roberto Tapia-Conyer;  Michal L. Schwartzman;  Aris Baras;  Manuel A. R. Ferreira;  Luca A. Lotta
收藏  |  浏览/下载:26/0  |  提交时间:2021/07/27
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters 期刊论文
Science, 2020
作者:  Alina Baum;  Dharani Ajithdoss;  Richard Copin;  Anbo Zhou;  Kathryn Lanza;  Nicole Negron;  Min Ni;  Yi Wei;  Kusha Mohammadi;  Bret Musser;  Gurinder S. Atwal;  Adelekan Oyejide;  Yenny Goez-Gazi;  John Dutton;  Elizabeth Clemmons;  Hilary M. Staples;  Carmen Bartley;  Benjamin Klaffke;  Kendra Alfson;  Michal Gazi;  Olga Gonzalez;  Edward Dick;  Ricardo Carrion;  Laurent Pessaint;  Maciel Porto;  Anthony Cook;  Renita Brown;  Vaneesha Ali;  Jack Greenhouse;  Tammy Taylor;  Hanne Andersen;  Mark G. Lewis;  Neil Stahl;  Andrew J. Murphy;  George D. Yancopoulos;  Christos A. Kyratsous
收藏  |  浏览/下载:13/0  |  提交时间:2020/11/30
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail 期刊论文
Science, 2020
作者:  Johanna Hansen;  Alina Baum;  Kristen E. Pascal;  Vincenzo Russo;  Stephanie Giordano;  Elzbieta Wloga;  Benjamin O. Fulton;  Ying Yan;  Katrina Koon;  Krunal Patel;  Kyung Min Chung;  Aynur Hermann;  Erica Ullman;  Jonathan Cruz;  Ashique Rafique;  Tammy Huang;  Jeanette Fairhurst;  Christen Libertiny;  Marine Malbec;  Wen-yi Lee;  Richard Welsh;  Glen Farr;  Seth Pennington;  Dipali Deshpande;  Jemmie Cheng;  Anke Watty;  Pascal Bouffard;  Robert Babb;  Natasha Levenkova;  Calvin Chen;  Bojie Zhang;  Annabel Romero Hernandez;  Kei Saotome;  Yi Zhou;  Matthew Franklin;  Sumathi Sivapalasingam;  David Chien Lye;  Stuart Weston;  James Logue;  Robert Haupt;  Matthew Frieman;  Gang Chen;  William Olson;  Andrew J. Murphy;  Neil Stahl;  George D. Yancopoulos;  Christos A. Kyratsous
收藏  |  浏览/下载:14/0  |  提交时间:2020/08/25
Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies 期刊论文
Science, 2020
作者:  Alina Baum;  Benjamin O. Fulton;  Elzbieta Wloga;  Richard Copin;  Kristen E. Pascal;  Vincenzo Russo;  Stephanie Giordano;  Kathryn Lanza;  Nicole Negron;  Min Ni;  Yi Wei;  Gurinder S. Atwal;  Andrew J. Murphy;  Neil Stahl;  George D. Yancopoulos;  Christos A. Kyratsous
收藏  |  浏览/下载:7/0  |  提交时间:2020/08/25