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Developmental cell programs are co-opted in inflammatory skin disease 期刊论文
Science, 2021
作者:  Gary Reynolds;  Peter Vegh;  James Fletcher;  Elizabeth F. M. Poyner;  Emily Stephenson;  Issac Goh;  Rachel A. Botting;  Ni Huang;  Bayanne Olabi;  Anna Dubois;  David Dixon;  Kile Green;  Daniel Maunder;  Justin Engelbert;  Mirjana Efremova;  Krzysztof Polański;  Laura Jardine;  Claire Jones;  Thomas Ness;  Dave Horsfall;  Jim McGrath;  Christopher Carey;  Dorin-Mirel Popescu;  Simone Webb;  Xiao-nong Wang;  Ben Sayer;  Jong-Eun Park;  Victor A. Negri;  Daria Belokhvostova;  Magnus D. Lynch;  David McDonald;  Andrew Filby;  Tzachi Hagai;  Kerstin B. Meyer;  Akhtar Husain;  Jonathan Coxhead;  Roser Vento-Tormo;  Sam Behjati;  Steven Lisgo;  Alexandra-Chloé Villani;  Jaume Bacardit;  Philip H. Jones;  Edel A. O’Toole;  Graham S. Ogg;  Neil Rajan;  Nick J. Reynolds;  Sarah A. Teichmann;  Fiona M. Watt;  Muzlifah Haniffa
收藏  |  浏览/下载:15/0  |  提交时间:2021/01/28
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike 期刊论文
Science, 2020
作者:  Michael Schoof;  Bryan Faust;  Reuben A. Saunders;  Smriti Sangwan;  Veronica Rezelj;  Nick Hoppe;  Morgane Boone;  Christian B. Billesbølle;  Cristina Puchades;  Caleigh M. Azumaya;  Huong T. Kratochvil;  Marcell Zimanyi;  Ishan Deshpande;  Jiahao Liang;  Sasha Dickinson;  Henry C. Nguyen;  Cynthia M. Chio;  Gregory E. Merz;  Michael C. Thompson;  Devan Diwanji;  Kaitlin Schaefer;  Aditya A. Anand;  Niv Dobzinski;  Beth Shoshana Zha;  Camille R. Simoneau;  Kristoffer Leon;  Kris M. White;  Un Seng Chio;  Meghna Gupta;  Mingliang Jin;  Fei Li;  Yanxin Liu;  Kaihua Zhang;  David Bulkley;  Ming Sun;  Amber M. Smith;  Alexandrea N. Rizo;  Frank Moss;  Axel F. Brilot;  Sergei Pourmal;  Raphael Trenker;  Thomas Pospiech;  Sayan Gupta;  Benjamin Barsi-Rhyne;  Vladislav Belyy;  Andrew W. Barile-Hill;  Silke Nock;  Yuwei Liu;  Nevan J. Krogan;  Corie Y. Ralston;  Danielle L. Swaney;  Adolfo García-Sastre;  Melanie Ott;  Marco Vignuzzi;  QCRG Structural Biology Consortium4‡;  Peter Walter;  Aashish Manglik
收藏  |  浏览/下载:15/0  |  提交时间:2020/12/22
Potential for large-scale CO2 removal via enhanced rock weathering with croplands 期刊论文
NATURE, 2020, 583 (7815) : 242-+
作者:  David J. Beerling;  Euripides P. Kantzas;  Mark R. Lomas;  Peter Wade;  Rafael M. Eufrasio;  Phil Renforth;  Binoy Sarkar;  M. Grace Andrews;  Rachael H. James;  Christopher R. Pearce;  Jean-Francois Mercure;  Hector Pollitt;  Philip B. Holden;  Neil R. Edwards;  Madhu Khanna;  Lenny Koh;  Shaun Quegan;  Nick F. Pidgeon;  Ivan A. Janssens;  James Hansen;  Steven A. Banwart
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/14

Enhanced silicate rock weathering (ERW), deployable with croplands, has potential use for atmospheric carbon dioxide (CO2) removal (CDR), which is now necessary to mitigate anthropogenic climate change(1). ERW also has possible co-benefits for improved food and soil security, and reduced ocean acidification(2-4). Here we use an integrated performance modelling approach to make an initial techno-economic assessment for 2050, quantifying how CDR potential and costs vary among nations in relation to business-as-usual energy policies and policies consistent with limiting future warming to 2 degrees Celsius(5). China, India, the USA and Brazil have great potential to help achieve average global CDR goals of 0.5 to 2gigatonnes of carbon dioxide (CO2) per year with extraction costs of approximately US$80-180 per tonne of CO2. These goals and costs are robust, regardless of future energy policies. Deployment within existing croplands offers opportunities to align agriculture and climate policy. However, success will depend upon overcoming political and social inertia to develop regulatory and incentive frameworks. We discuss the challenges and opportunities of ERW deployment, including the potential for excess industrial silicate materials (basalt mine overburden, concrete, and iron and steel slag) to obviate the need for new mining, as well as uncertainties in soil weathering rates and land-ocean transfer of weathered products.


  
Characterizing soundscapes across diverse ecosystems using a universal acoustic feature set 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (29) : 17049-17055
作者:  Sethi, Sarab S.;  Jones, Nick S.;  Fulcher, Ben D.;  Picinali, Lorenzo;  Clink, Dena Jane;  Klinck, Holger;  Orme, C. David L.;  Wrege, Peter H.;  Ewers, Robert M.
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/09
machine learning  acoustic  soundscape  monitoring  ecology  
Simulating rewetting events in intermittent rivers and ephemeral streams: A global analysis of leached nutrients and organic matter 期刊论文
GLOBAL CHANGE BIOLOGY, 2019, 25 (5) : 1591-1611
作者:  Shumilova, Oleksandra;  Zak, Dominik;  Datry, Thibault;  von Schiller, Daniel;  Corti, Roland;  Foulquier, Arnaud;  Obrador, Biel;  Tockner, Klement;  Allan, Daniel C.;  Altermatt, Florian;  Isabel Arce, Maria;  Arnon, Shai;  Banas, Damien;  Banegas-Medina, Andy;  Beller, Erin;  Blanchette, Melanie L.;  Blanco-Libreros, Juan F.;  Blessing, Joanna;  Boechat, Iola Goncalves;  Boersma, Kate;  Bogan, Michael T.;  Bonada, Nuria;  Bond, Nick R.;  Brintrup, Kate;  Bruder, Andreas;  Burrows, Ryan;  Cancellario, Tommaso;  Carlson, Stephanie M.;  Cauvy-Fraunie, Sophie;  Cid, Nuria;  Danger, Michael;  de Freitas Terra, Bianca;  De Girolamo, Anna Maria;  del Campo, Ruben;  Dyer, Fiona;  Elosegi, Arturo;  Faye, Emile;  Febria, Catherine;  Figueroa, Ricardo;  Four, Brian;  Gessner, Mark O.;  Gnohossou, Pierre;  Cerezo, Rosa Gomez;  Gomez-Gener, Lluis;  Graca, Manuel A. S.;  Guareschi, Simone;  Guecker, Bjoern;  Hwan, Jason L.;  Kubheka, Skhumbuzo;  Langhans, Simone Daniela;  Leigh, Catherine;  Little, Chelsea J.;  Lorenz, Stefan;  Marshall, Jonathan;  McIntosh, Angus;  Mendoza-Lera, Clara;  Meyer, Elisabeth Irmgard;  Milisa, Marko;  Mlambo, Musa C.;  Moleon, Marcos;  Negus, Peter;  Niyogi, Dev;  Papatheodoulou, Athina;  Pardo, Isabel;  Paril, Petr;  Pesic, Vladimir;  Rodriguez-Lozano, Pablo;  Rolls, Robert J.;  Sanchez-Montoya, Maria Mar;  Savic, Ana;  Steward, Alisha;  Stubbington, Rachel;  Taleb, Amina;  Vander Vorste, Ross;  Waltham, Nathan;  Zoppini, Annamaria;  Zarfl, Christiane
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/26
biofilms  leaching  leaf litter  rewetting  sediments  temporary rivers  
A two-dimensional Dirac fermion microscope 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Boggild, Peter;  Caridad, Jose M.;  Stampfer, Christoph;  Calogero, Gaetano;  Papior, Nick Rubner;  Brandbyge, Mads
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/27
Whole-genome resequencing of 472 Vitis accessions for grapevine diversity and demographic history analyses 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Liang, Zhenchang;  Duan, Shengchang;  Sheng, Jun;  Zhu, Shusheng;  Ni, Xuemei;  Shao, Jianhui;  Liu, Chonghuai;  Nick, Peter;  Du, Fei;  Fan, Peige;  Mao, Ruzhi;  Zhu, Yifan;  Deng, Weiping;  Yang, Min;  Huang, Huichuan;  Liu, Yixiang;  Ding, Yiqing;  Liu, Xianju;  Jiang, Jianfu;  Zhu, Youyong;  Li, Shaohua;  He, Xiahong;  Chen, Wei;  Dong, Yang
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Roymans, Dirk;  Alnajjar, Sarhad S.;  Battles, Michael B.;  Sitthicharoenchai, Panchan;  Furmanova-Hollenstein, Polina;  Rigaux, Peter;  Van den Berg, Joke;  Kwanten, Leen;  Van Ginderen, Marcia;  Verheyen, Nick;  Vranckx, Luc;  Jaensch, Steffen;  Arnoult, Eric;  Voorzaat, Richard;  Gallup, Jack M.;  Larios-Mora, Alejandro;  Crabbe, Marjolein;  Huntjens, Dymphy;  Raboisson, Pierre;  Langedijk, Johannes P.;  Ackermann, Mark R.;  McLellan, Jason S.;  Vendeville, Sandrine;  Koul, Anil
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
Ecology shapes the evolutionary trade-off between predator avoidance and defence in coral reef butterflyfishes 期刊论文
ECOLOGY LETTERS, 2018, 21 (7) : 1033-1042
作者:  Hodge, Jennifer R.;  Alim, Chidera;  Bertrand, Nick G.;  Lee, Wesley;  Price, Samantha A.;  Tran, Binh;  Wainwright, Peter C.
收藏  |  浏览/下载:5/0  |  提交时间:2019/04/09
Chaetodontidae  constraint  coral reef ecology  evolutionary trade-off  foraging strategy  functional morphology  phylogenetic comparative method  predation risk  social behaviour  spines  
Whole-genome landscapes of major melanoma subtypes 期刊论文
NATURE, 2017, 545 (7653) : 175-180
作者:  Hayward, Nicholas K.;  Wilmott, James S.;  Waddell, Nicola;  Johansson, Peter A.;  Field, Matthew A.;  Nones, Katia;  Patch, Ann-Marie;  Kakavand, Hojabr;  Alexandrov, Ludmil B.;  Burke, Hazel;  Jakrot, Valerie;  Kazakoff, Stephen;  Holmes, Oliver;  Leonard, Conrad;  Sabarinathan, Radhakrishnan;  Mularoni, Loris;  Wood, Scott;  Xu, Qinying;  Waddell, Nick;  Tembe, Varsha;  Pupo, Gulietta M.;  De Paoli-Iseppi, Ricardo;  Vilain, Ricardo E.;  Shang, Ping;  Lau, Loretta M. S.;  Dagg, Rebecca A.;  Schramm, Sarah-Jane;  Pritchard, Antonia;  Dutton-Regester, Ken;  Newell, Felicity;  Fitzgerald, Anna;  Shang, Catherine A.;  Grimmond, Sean M.;  Pickett, Hilda A.;  Yang, Jean Y.;  Stretch, Jonathan R.;  Behren, Andreas;  Kefford, Richard F.;  Hersey, Peter;  Long, Georgina V.;  Cebon, Jonathan;  Shackleton, Mark;  Spillane, Andrew J.;  Saw, Robyn P. M.;  Lopez-Bigas, Nuria;  Pearson, John V.;  Thompson, John F.;  Scolyer, Richard A.;  Mann, Graham J.
收藏  |  浏览/下载:15/0  |  提交时间:2019/04/09