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The lysosomal Rag-Ragulator complex licenses RIPK1– and caspase-8–mediated pyroptosis by Yersinia 期刊论文
Science, 2021
作者:  Zengzhang Zheng;  Wanyan Deng;  Yang Bai;  Rui Miao;  Shenglin Mei;  Zhibin Zhang;  Youdong Pan;  Yi Wang;  Rui Min;  Fan Deng;  Zeyu Wu;  Wu Li;  Pengcheng Chen;  Tianchi Ma;  Xiwen Lou;  Judy Lieberman;  Xing Liu
收藏  |  浏览/下载:9/0  |  提交时间:2021/07/27
A human cell atlas of fetal gene expression 期刊论文
Science, 2020
作者:  Junyue Cao;  Diana R. O’Day;  Hannah A. Pliner;  Paul D. Kingsley;  Mei Deng;  Riza M. Daza;  Michael A. Zager;  Kimberly A. Aldinger;  Ronnie Blecher-Gonen;  Fan Zhang;  Malte Spielmann;  James Palis;  Dan Doherty;  Frank J. Steemers;  Ian A. Glass;  Cole Trapnell;  Jay Shendure
收藏  |  浏览/下载:14/0  |  提交时间:2020/11/20
Economics in the Age of COVID-19 期刊论文
NATURE, 2020, 581 (7809) : 375-377
作者:  Yin, Juan;  Li, Yu-Huai;  Liao, Sheng-Kai;  Yang, Meng;  Cao, Yuan;  Zhang, Liang;  Ren, Ji-Gang;  Cai, Wen-Qi;  Liu, Wei-Yue;  Li, Shuang-Lin;  Shu, Rong;  Huang, Yong-Mei;  Deng, Lei;  Li, Li;  Zhang, Qiang;  Liu, Nai-Le
收藏  |  浏览/下载:25/0  |  提交时间:2020/07/03

Breakneck triage nails many diagnoses, but deeper treatment is needed.


Breakneck triage nails many diagnoses, but deeper treatment is needed.


  
Obesogenic environmental factors of adult obesity in China: a nationally representative cross-sectional study 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (4)
作者:  Zhang, Xiao;  Zhang, Mei;  Zhao, Zhenping;  Huang, Zhengjing;  Deng, Qian;  Li, Yichong;  Pan, An;  Li, Chun;  Chen, Zhihua;  Zhou, Maigeng;  Yu, Chao;  Stein, Alfred;  Jia, Peng;  Wang, Limin
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/02
obesity  adult  physical environment  built environment  food environment  socioeconomic environment  
Recycling and metabolic flexibility dictate life in the lower oceanic crust 期刊论文
NATURE, 2020, 579 (7798) : 250-+
作者:  Zhou, Peng;  Yang, Xing-Lou;  Wang, Xian-Guang;  Hu, Ben;  Zhang, Lei;  Zhang, Wei;  Si, Hao-Rui;  Zhu, Yan;  Li, Bei;  Huang, Chao-Lin;  Chen, Hui-Dong;  Chen, Jing;  Luo, Yun;  Guo, Hua;  Jiang, Ren-Di;  Liu, Mei-Qin;  Chen, Ying;  Shen, Xu-Rui;  Wang, Xi;  Zheng, Xiao-Shuang;  Zhao, Kai;  Chen, Quan-Jiao;  Deng, Fei;  Liu, Lin-Lin;  Yan, Bing;  Zhan, Fa-Xian;  Wang, Yan-Yi;  Xiao, Geng-Fu;  Shi, Zheng-Li
收藏  |  浏览/下载:37/0  |  提交时间:2020/05/13

The lithified lower oceanic crust is one of Earth'  s last biological frontiers as it is difficult to access. It is challenging for microbiota that live in marine subsurface sediments or igneous basement to obtain sufficient carbon resources and energy to support growth(1-3) or to meet basal power requirements(4) during periods of resource scarcity. Here we show how limited and unpredictable sources of carbon and energy dictate survival strategies used by low-biomass microbial communities that live 10-750 m below the seafloor at Atlantis Bank, Indian Ocean, where Earth'  s lower crust is exposed at the seafloor. Assays of enzyme activities, lipid biomarkers, marker genes and microscopy indicate heterogeneously distributed and viable biomass with ultralow cell densities (fewer than 2,000 cells per cm(3)). Expression of genes involved in unexpected heterotrophic processes includes those with a role in the degradation of polyaromatic hydrocarbons, use of polyhydroxyalkanoates as carbon-storage molecules and recycling of amino acids to produce compounds that can participate in redox reactions and energy production. Our study provides insights into how microorganisms in the plutonic crust are able to survive within fractures or porous substrates by coupling sources of energy to organic and inorganic carbon resources that are probably delivered through the circulation of subseafloor fluids or seawater.


  
Amplification of black carbon light absorption induced by atmospheric aging: temporal variation at seasonal and diel scales in urban Guangzhou 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (4) : 2445-2470
作者:  Sun, Jia Yin;  Wu, Cheng;  Wu, Dui;  Cheng, Chunlei;  Li, Mei;  Li, Lei;  Deng, Tao;  Yu, Jian Zhen;  Li, Yong Jie;  Zhou, Qianni;  Liang, Yue;  Sun, Tianlin;  Song, Lang;  Cheng, Peng;  Yang, Wenda;  Pei, Chenglei;  Chen, Yanning;  Cen, Yanxiang;  Nian, Huiqing;  Zhou, Zhen
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/02
Spatiotemporal expansion of primary progenitor zones in the developing human cerebellum 期刊论文
SCIENCE, 2019, 366 (6464) : 454-+
作者:  Haldipur, Parthiv;  Aldinger, Kimberly A.;  Bernardo, Silvia;  Deng, Mei;  Timms, Andrew E.;  Overman, Lynne M.;  Winter, Conrad;  Lisgo, Steven N.;  Razavi, Ferechte;  Silvestri, Evelina;  Manganaro, Lucia;  Adle-Biasette, Homa;  Guilmiot, Fabien;  Russo, Rosa;  Kidron, Debora;  Hof, Patrick R.;  Gerrelli, Dianne;  Lindsay, Susan J.;  Dobyns, William B.;  Glass, Ian A.;  Alexandre, Paula;  Millen, Kathleen J.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
Evidence for fungi and gold redox interaction under Earth surface conditions 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Bohu, Tsing;  Anand, Ravi;  Noble, Ryan;  Lintern, Mel;  Kaksonen, Anna H.;  Mei, Yuan;  Cheng, Ka Yu;  Deng, Xiao;  Veder, Jean-Pierre;  Bunce, Michael;  Power, Matthew;  Verrall, Mike
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
DNA methylation repels targeting of Arabidopsis REF6 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Qiu, Qi;  Mei, Hailiang;  Deng, Xian;  He, Kaixuan;  Wu, Baixing;  Yao, Qingqing;  Zhang, Jixiang;  Lu, Falong;  Ma, Jinbiao;  Cao, Xiaofeng
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
Characteristics of marine shipping emissions at berth: profiles for particulate matter and volatile organic compounds 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2018, 18 (13) : 9527-9545
作者:  Xiao, Qian;  Li, Mei;  Liu, Huan;  Fu, Mingliang;  Deng, Fanyuan;  Lv, Zhaofeng;  Man, Hanyang;  Jin, Xinxin;  Liu, Shuai;  He, Kebin
收藏  |  浏览/下载:6/0  |  提交时间:2019/04/09