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Targeted selection of HIV-specific antibody mutations by engineering B cell maturation 期刊论文
SCIENCE, 2019, 366 (6470) : 1215-+
作者:  Saunders, Kevin O.;  Wiehe, Kevin;  Tian, Ming;  Acharya, Priyamvada;  Bradley, Todd;  Alam, S. Munir;  Go, Eden P.;  Scearce, Richard;  Sutherland, Laura;  Henderson, Rory;  Hsu, Allen L.;  Borgnia, Mario J.;  Chen, Haiyan;  Lu, Xiaozhi;  Wu, Nelson R.;  Watts, Brian;  Jiang, Chuancang;  Easterhoff, David;  Cheng, Hwei-Ling;  McGovern, Kelly;  Waddicor, Peyton;  Chapdelaine-Williams, Aimee;  Eaton, Amanda;  Zhang, Jinsong;  Rountree, Wes;  Verkoczy, Laurent;  Tomai, Mark;  Lewis, Mark G.;  Desaire, Heather R.;  Edwards, Robert J.;  Cain, Derek W.;  Bonsignori, Mattia;  Montefiori, David;  Alt, Frederick W.;  Haynes, Barton F.
收藏  |  浏览/下载:13/0  |  提交时间:2020/02/17
Clonal hematopoiesis in human aging and disease 期刊论文
SCIENCE, 2019, 366 (6465) : 586-+
作者:  Jaiswal, Siddhartha;  Ebert, Benjamin L.
收藏  |  浏览/下载:4/0  |  提交时间:2020/02/17
Higher-fitness yeast genotypes are less robust to deleterious mutations 期刊论文
SCIENCE, 2019, 366 (6464) : 490-+
作者:  Johnson, Milo S.;  Martsul, Alena;  Kryazhimskiy, Sergey;  Desai, Michael M.
收藏  |  浏览/下载:1/0  |  提交时间:2019/11/27
Microbial metabolites control the thymic development of mucosal-associated invariant T cells 期刊论文
SCIENCE, 2019, 366 (6464) : 494-+
作者:  Legoux, Francois;  Bellet, Deborah;  Daviaud, Celine;  El Morr, Yara;  Darbois, Aurelie;  Niort, Kristina;  Procopio, Emanuele;  Salou, Marion;  Gilet, Jules;  Ryffel, Bernhard;  Balvay, Aurelie;  Foussier, Anne;  Sarkis, Manal;  El Marjou, Ahmed;  Schmidt, Frederic;  Rabot, Sylvie;  Lantz, Olivier
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Adaptive archaic introgression of copy number variants and the discovery of previously unknown human genes 期刊论文
SCIENCE, 2019, 366 (6463) : 324-+
作者:  Hsieh, PingHsun;  Vollger, Mitchell R.;  Dang, Vy;  Porubsky, David;  Baker, Carl;  Cantsilieris, Stuart;  Hoekzema, Kendra;  Lewis, Alexandra P.;  Munson, Katherine M.;  Sorensen, Melanie;  Kronenberg, Zev N.;  Murali, Shwetha;  Nelson, Bradley J.;  Chiatante, Giorgia;  Maggiolini, Flavia Angela Maria;  Blanche, Helene;  Underwood, Jason G.;  Antonacci, Francesca;  Deleuze, Jean-Francois;  Eichler, Evan E.
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/27
Chromosome errors in human eggs shape natural fertility over reproductive life span 期刊论文
SCIENCE, 2019, 365 (6460) : 1466-+
作者:  Gruhn, Jennifer R.;  Zielinska, Agata P.;  Shukla, Vallari;  Blanshard, Robert;  Capalbo, Antonio;  Cimadomo, Danilo;  Nikiforov, Dmitry;  Chan, Andrew Chi-Ho;  Newnham, Louise J.;  Vogel, Ivan;  Scarica, Catello;  Krapchev, Marta;  Taylor, Deborah;  Kristensen, Stine Gry;  Cheng, Junping;  Ernst, Erik;  Bjorn, Anne-Mette Bay;  Colmorn, Lotte Berdiin;  Blayney, Martyn;  Elder, Kay;  Liss, Joanna;  Hartshorne, Geraldine;  Grondahl, Marie Louise;  Rienzi, Laura;  Ubaldi, Filippo;  McCoy, Rajiv;  Lukaszuk, Krzysztof;  Andersen, Claus Yding;  Schuh, Melina;  Hoffmann, Eva R.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
Senescence in immunity against helminth parasites predicts adult mortality in a wild mammal 期刊论文
SCIENCE, 2019, 365 (6459) : 1296-+
作者:  Froy, H.;  Sparks, A. M.;  Watt, K.;  Sinclair, R.;  Bach, F.;  Pilkington, J. G.;  Pemberton, J. M.;  McNeilly, T. N.;  Nussey, D. H.
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
Major subpopulations of Plasmodium falciparum in sub-Saharan Africa 期刊论文
SCIENCE, 2019, 365 (6455) : 813-+
作者:  Amambua-Ngwa, Alfred;  39;Alessandro, Umberto
收藏  |  浏览/下载:1/0  |  提交时间:2019/11/27
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies 期刊论文
SCIENCE, 2019, 365 (6453) : 599-+
作者:  Boettcher, Steffen;  Miller, Peter G.;  Sharma, Rohan;  McConkey, Marie;  Leventhal, Matthew;  Krivtsov, Andrei V.;  Giacomelli, Andrew O.;  Wong, Waihay;  Kim, Jesi;  Chao, Sherry;  Kurppa, Kari J.;  Yang, Xiaoping;  Milenkowic, Kirsten;  Piccioni, Federica;  Root, David E.;  Ruecker, Frank G.;  Flamand, Yael;  Neuberg, Donna;  Lindsley, R. Coleman;  Janne, Pasi A.;  Hahn, William C.;  Jacks, Tyler;  Doehner, Hartmut;  Armstrong, Scott A.;  Ebert, Benjamin L.
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27
Contrasting genomic shifts underlie parallel phenotypic evolution in response to fishing 期刊论文
SCIENCE, 2019, 365 (6452) : 487-+
作者:  Therkildsen, Nina O.;  Wilder, Aryn P.;  Conover, David O.;  Munch, Stephan B.;  Baumann, Hannes;  Palumbi, Stephen R.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27