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Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants 期刊论文
Science, 2021
作者:  Lingshu Wang;  Tongqing Zhou;  Yi Zhang;  Eun Sung Yang;  Chaim A. Schramm;  Wei Shi;  Amarendra Pegu;  Olamide K. Oloniniyi;  Amy R. Henry;  Samuel Darko;  Sandeep R. Narpala;  Christian Hatcher;  David R. Martinez;  Yaroslav Tsybovsky;  Emily Phung;  Olubukola M. Abiona;  Avan Antia;  Evan M. Cale;  Lauren A. Chang;  Misook Choe;  Kizzmekia S. Corbett;  Rachel L. Davis;  Anthony T. DiPiazza;  Ingelise J. Gordon;  Sabrina Helmold Hait;  Tandile Hermanus;  Prudence Kgagudi;  Farida Laboune;  Kwanyee Leung;  Tracy Liu;  Rosemarie D. Mason;  Alexandra F. Nazzari;  Laura Novik;  Sarah O’Connell;  Sijy O’Dell;  Adam S. Olia;  Stephen D. Schmidt;  Tyler Stephens;  Christopher D. Stringham;  Chloe Adrienna Talana;  I-Ting Teng;  Danielle A. Wagner;  Alicia T. Widge;  Baoshan Zhang;  Mario Roederer;  Julie E. Ledgerwood;  Tracy J. Ruckwardt;  Martin R. Gaudinski;  Penny L. Moore;  Nicole A. Doria-Rose;  Ralph S. Baric;  Barney S. Graham;  Adrian B. McDermott;  Daniel C. Douek;  Peter D. Kwong;  John R. Mascola;  Nancy J. Sullivan;  John Misasi
收藏  |  浏览/下载:21/0  |  提交时间:2021/08/17
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model 期刊论文
Science, 2020
作者:  Thomas F. Rogers;  Fangzhu Zhao;  Deli Huang;  Nathan Beutler;  Alison Burns;  Wan-ting He;  Oliver Limbo;  Chloe Smith;  Ge Song;  Jordan Woehl;  Linlin Yang;  Robert K. Abbott;  Sean Callaghan;  Elijah Garcia;  Jonathan Hurtado;  Mara Parren;  Linghang Peng;  Sydney Ramirez;  James Ricketts;  Michael J. Ricciardi;  Stephen A. Rawlings;  Nicholas C. Wu;  Meng Yuan;  Davey M. Smith;  David Nemazee;  John R. Teijaro;  James E. Voss;  Ian A. Wilson;  Raiees Andrabi;  Bryan Briney;  Elise Landais;  Devin Sok;  Joseph G. Jardine;  Dennis R. Burton
收藏  |  浏览/下载:19/0  |  提交时间:2020/08/25
Insights from Earth system model initial-condition large ensembles and future prospects (vol 89, pg 516, 2020) 期刊论文
NATURE CLIMATE CHANGE, 2020
作者:  Deser, C.;  Lehner, F.;  Rodgers, K. B.;  Ault, T.;  Delworth, T. L.;  DiNezio, P. N.;  Fiore, A.;  Frankignoul, C.;  Fyfe, J. C.;  Horton, D. E.;  Kay, J. E.;  Knutti, R.;  Lovenduski, N. S.;  Marotzke, J.;  McKinnon, K. A.;  Minobe, S.;  Randerson, J.;  Screen, J. A.;  Simpson, I. R.;  Ting, M.
收藏  |  浏览/下载:8/0  |  提交时间:2020/06/29
Insights from Earth system model initial-condition large ensembles and future prospects 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (4) : 277-+
作者:  Deser, C.;  Lehner, F.;  Rodgers, K. B.;  Ault, T.;  Delworth, T. L.;  DiNezio, P. N.;  Fiore, A.;  Frankignoul, C.;  Fyfe, J. C.;  Horton, D. E.;  Kay, J. E.;  Knutti, R.;  Lovenduski, N. S.;  Marotzke, J.;  McKinnon, K. A.;  Minobe, S.;  Randerson, J.;  Screen, J. A.;  Simpson, I. R.;  Ting, M.
收藏  |  浏览/下载:11/0  |  提交时间:2020/05/13
Highly porous nature of a primitive asteroid revealed by thermal imaging 期刊论文
NATURE, 2020, 579 (7800) : 518-522
作者:  Quinn, Robert A.;  Melnik, Alexey, V;  Vrbanac, Alison;  Fu, Ting;  Patras, Kathryn A.;  Christy, Mitchell P.;  Bodai, Zsolt;  Belda-Ferre, Pedro;  Tripathi, Anupriya;  Chung, Lawton K.;  Downes, Michael;  Welch, Ryan D.;  Quinn, Melissa;  Humphrey, Greg;  Panitchpakdi, Morgan;  Weldon, Kelly C.;  Aksenov, Alexander;  da Silva, Ricardo;  Avila-Pacheco, Julian;  Clish, Clary;  Bae, Sena;  Mallick, Himel;  Franzosa, Eric A.;  Lloyd-Price, Jason;  Bussell, Robert;  Thron, Taren;  Nelson, Andrew T.;  Wang, Mingxun;  Leszczynski, Eric;  Vargas, Fernando;  Gauglitz, Julia M.;  Meehan, Michael J.;  Gentry, Emily;  Arthur, Timothy D.;  Komor, Alexis C.;  Poulsen, Orit;  Boland, Brigid S.;  Chang, John T.;  Sandborn, William J.;  Lim, Meerana;  Garg, Neha;  Lumeng, Julie C.;  Xavier, Ramnik J.;  Kazmierczak, Barbara, I;  Jain, Ruchi;  Egan, Marie;  Rhee, Kyung E.;  Ferguson, David;  Raffatellu, Manuela;  Vlamakis, Hera;  Haddad, Gabriel G.;  Siegel, Dionicio;  Huttenhower, Curtis;  Mazmanian, Sarkis K.;  Evans, Ronald M.;  Nizet, Victor;  Knight, Rob;  Dorrestein, Pieter C.
收藏  |  浏览/下载:46/0  |  提交时间:2020/05/13

Carbonaceous (C-type) asteroids(1) are relics of the early Solar System that have preserved primitive materials since their formation approximately 4.6 billion years ago. They are probably analogues of carbonaceous chondrites(2,3) and are essential for understanding planetary formation processes. However, their physical properties remain poorly known because carbonaceous chondrite meteoroids tend not to survive entry to Earth'  s atmosphere. Here we report on global one-rotation thermographic images of the C-type asteroid 162173 Ryugu, taken by the thermal infrared imager (TIR)(4) onboard the spacecraft Hayabusa2(5), indicating that the asteroid'  s boulders and their surroundings have similar temperatures, with a derived thermal inertia of about 300 J m(-2) s(-0.5) K-1 (300 tiu). Contrary to predictions that the surface consists of regolith and dense boulders, this low thermal inertia suggests that the boulders are more porous than typical carbonaceous chondrites(6) and that their surroundings are covered with porous fragments more than 10 centimetres in diameter. Close-up thermal images confirm the presence of such porous fragments and the flat diurnal temperature profiles suggest a strong surface roughness effect(7,8). We also observed in the close-up thermal images boulders that are colder during the day, with thermal inertia exceeding 600 tiu, corresponding to dense boulders similar to typical carbonaceous chondrites(6). These results constrain the formation history of Ryugu: the asteroid must be a rubble pile formed from impact fragments of a parent body with microporosity(9) of approximately 30 to 50 per cent that experienced a low degree of consolidation. The dense boulders might have originated from the consolidated innermost region or they may have an exogenic origin. This high-porosity asteroid may link cosmic fluffy dust to dense celestial bodies(10).


Thermal imaging data obtained from the spacecraft Hayabusa2 reveal that the carbonaceous asteroid 162173 Ryugu is an object of unusually high porosity.


  
DeepCropNet: a deep spatial-temporal learning framework for county-level corn yield estimation 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (3)
作者:  Lin, Tao;  Zhong, Renhai;  Wang, Yudi;  Xu, Jinfan;  Jiang, Hao;  Xu, Jialu;  Ying, Yibin;  Rodriguez, Luis;  Ting, K. C.;  Li, Haifeng
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/02
yield estimation  corn  LSTM  attention mechanism  multi-task learning  deep learning  
Experimental demonstration of memory-enhanced quantum communication 期刊论文
NATURE, 2020
作者:  Quinn, Robert A.;  Melnik, Alexey, V;  Vrbanac, Alison;  Fu, Ting;  Patras, Kathryn A.;  Christy, Mitchell P.;  Bodai, Zsolt;  Belda-Ferre, Pedro;  Tripathi, Anupriya;  Chung, Lawton K.;  Downes, Michael;  Welch, Ryan D.;  Quinn, Melissa;  Humphrey, Greg;  Panitchpakdi, Morgan;  Weldon, Kelly C.;  Aksenov, Alexander;  da Silva, Ricardo;  Avila-Pacheco, Julian;  Clish, Clary;  Bae, Sena;  Mallick, Himel;  Franzosa, Eric A.;  Lloyd-Price, Jason;  Bussell, Robert;  Thron, Taren;  Nelson, Andrew T.;  Wang, Mingxun;  Leszczynski, Eric;  Vargas, Fernando;  Gauglitz, Julia M.;  Meehan, Michael J.;  Gentry, Emily;  Arthur, Timothy D.;  Komor, Alexis C.;  Poulsen, Orit;  Boland, Brigid S.;  Chang, John T.;  Sandborn, William J.;  Lim, Meerana;  Garg, Neha;  Lumeng, Julie C.;  Xavier, Ramnik J.;  Kazmierczak, Barbara, I;  Jain, Ruchi;  Egan, Marie;  Rhee, Kyung E.;  Ferguson, David;  Raffatellu, Manuela;  Vlamakis, Hera;  Haddad, Gabriel G.;  Siegel, Dionicio;  Huttenhower, Curtis;  Mazmanian, Sarkis K.;  Evans, Ronald M.;  Nizet, Victor;  Knight, Rob;  Dorrestein, Pieter C.
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/03

The ability to communicate quantum information over long distances is of central importance in quantum science and engineering(1). Although some applications of quantum communication such as secure quantum key distribution(2,3) are already being successfully deployed(4-7), their range is currently limited by photon losses and cannot be extended using straightforward measure-and-repeat strategies without compromising unconditional security(8). Alternatively, quantum repeaters(9), which utilize intermediate quantum memory nodes and error correction techniques, can extend the range of quantum channels. However, their implementation remains an outstanding challenge(10-16), requiring a combination of efficient and high-fidelity quantum memories, gate operations, and measurements. Here we use a single solid-state spin memory integrated in a nanophotonic diamond resonator(17-19) to implement asynchronous photonic Bell-state measurements, which are a key component of quantum repeaters. In a proof-of-principle experiment, we demonstrate high-fidelity operation that effectively enables quantum communication at a rate that surpasses the ideal loss-equivalent direct-transmission method while operating at megahertz clock speeds. These results represent a crucial step towards practical quantum repeaters and large-scale quantum networks(20,21).


A solid-state spin memory is used to demonstrate quantum repeater functionality, which has the potential to overcome photon losses involved in long-distance transmission of quantum information.


  
Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Yang, Ting-Lin B.;  Chen, Qijun;  Deng, Jennifer T.;  Jagannathan, Geetha;  Tobias, John W.;  Schultz, David C.;  Wang, Shan;  Lengner, Christopher J.;  Rustgi, Anil K.;  Lynch, John P.;  Johnson, F. Brad
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition (vol 363, eaaw7579, 2019) 期刊论文
SCIENCE, 2019, 363 (6425)
作者:  Yu, M.;  Bardia, A.;  Wittner, B. S.;  Stott, S. L.;  Smas, M. E.;  Ting, D. T.;  Isakoff, S. J.;  Ciciliano, J. C.;  Wells, M. N.;  Shah, A. M.;  Concannon, K. F.;  Donaldson, M. C.;  Sequist, L. V.;  Brachtel, E.;  Sgroi, D.;  Baselga, J.;  Ramaswamy, S.;  Toner, M.;  Haber, D. A.;  Maheswaran, S.
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Spatial distributions of airborne di-carbonyls in urban and rural areas in China 期刊论文
ATMOSPHERIC RESEARCH, 2017, 186: 43473
作者:  Lui, K. H.;  Dai, Wen-Ting;  Chan, C. S.;  Ho, Steven Sai Hang;  Cao, Jun-Ji;  Lee, S. C.;  Ho, K. F.
收藏  |  浏览/下载:5/0  |  提交时间:2019/04/09
Glyoxal  Methylglyoxal  Ambient air  Correlation analysis  Multiple linear regression