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An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike 期刊论文
Science, 2020
作者:  Michael Schoof;  Bryan Faust;  Reuben A. Saunders;  Smriti Sangwan;  Veronica Rezelj;  Nick Hoppe;  Morgane Boone;  Christian B. Billesbølle;  Cristina Puchades;  Caleigh M. Azumaya;  Huong T. Kratochvil;  Marcell Zimanyi;  Ishan Deshpande;  Jiahao Liang;  Sasha Dickinson;  Henry C. Nguyen;  Cynthia M. Chio;  Gregory E. Merz;  Michael C. Thompson;  Devan Diwanji;  Kaitlin Schaefer;  Aditya A. Anand;  Niv Dobzinski;  Beth Shoshana Zha;  Camille R. Simoneau;  Kristoffer Leon;  Kris M. White;  Un Seng Chio;  Meghna Gupta;  Mingliang Jin;  Fei Li;  Yanxin Liu;  Kaihua Zhang;  David Bulkley;  Ming Sun;  Amber M. Smith;  Alexandrea N. Rizo;  Frank Moss;  Axel F. Brilot;  Sergei Pourmal;  Raphael Trenker;  Thomas Pospiech;  Sayan Gupta;  Benjamin Barsi-Rhyne;  Vladislav Belyy;  Andrew W. Barile-Hill;  Silke Nock;  Yuwei Liu;  Nevan J. Krogan;  Corie Y. Ralston;  Danielle L. Swaney;  Adolfo García-Sastre;  Melanie Ott;  Marco Vignuzzi;  QCRG Structural Biology Consortium4‡;  Peter Walter;  Aashish Manglik
收藏  |  浏览/下载：15/0  |  提交时间：2020/12/22
STRUCTURAL BIOLOGY eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response 期刊论文
SCIENCE, 2019, 364 (6439) : 491-+
作者:  Kenner, Lillian R.;  Anand, Aditya A.;  Nguyen, Henry C.;  Myasnikov, Alexander G.;  Klose, Carolin J.;  McGeever, Lea A.;  Tsai, Jordan C.;  Miller-Vedam, Lakshmi E.;  Walter, Peter;  Frost, Adam
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/27
Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule 期刊论文
SCIENCE, 2018, 359 (6383) : 1483-+
作者:  Tsai, Jordan C.;  Miller-Vedam, Lakshmi E.;  Anand, Aditya A.;  Jaishankar, Priyadarshini;  Nguyen, Henry C.;  Renslo, Adam R.;  Frost, Adam;  Walter, Peter
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/27