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Quantum walks on a programmable two-dimensional 62-qubit superconducting processor 期刊论文
Science, 2021
作者:  Ming Gong;  Shiyu Wang;  Chen Zha;  Ming-Cheng Chen;  He-Liang Huang;  Yulin Wu;  Qingling Zhu;  Youwei Zhao;  Shaowei Li;  Shaojun Guo;  Haoran Qian;  Yangsen Ye;  Fusheng Chen;  Chong Ying;  Jiale Yu;  Daojin Fan;  Dachao Wu;  Hong Su;  Hui Deng;  Hao Rong;  Kaili Zhang;  Sirui Cao;  Jin Lin;  Yu Xu;  Lihua Sun;  Cheng Guo;  Na Li;  Futian Liang;  V. M. Bastidas;  Kae Nemoto;  W. J. Munro;  Yong-Heng Huo;  Chao-Yang Lu;  Cheng-Zhi Peng;  Xiaobo Zhu;  Jian-Wei Pan
收藏  |  浏览/下载:16/0  |  提交时间:2021/06/07
Sulfate formation is dominated by manganese-catalyzed oxidation of SO2 on aerosol surfaces during haze events 期刊论文
Nature Communications, 2021
作者:  Weigang Wang;  Mingyuan Liu;  Tiantian Wang;  Yu Song;  Li Zhou;  Junji Cao;  Jingnan Hu;  Guigang Tang;  Zhe Chen;  Zhijie Li;  Zhenying Xu;  Chao Peng;  Chaofan Lian;  Yan Chen;  Yuepeng Pan;  Yunhong Zhang;  Yele Sun;  Weijun Li;  Tong Zhu;  Hezhong Tian;  Maofa Ge
收藏  |  浏览/下载:15/0  |  提交时间:2021/04/06
Predicting Solute Transport through Green Stormwater Infrastructure with Unsteady Transit Time Distribution Theory 期刊论文
Water Resources Research, 2020
作者:  E. A. Parker;  S. B. Grant;  Y. Cao;  M. A. Rippy;  K. J. McGuire;  P. A. Holden;  M. Feraud;  S. Avasarala;  H. Liu;  W. C. Hung;  M. Rugh;  J. Jay;  J. Peng;  S. Shao;  D. Li
收藏  |  浏览/下载:11/0  |  提交时间:2020/12/28
Ancient DNA indicates human population shifts and admixture in northern and southern China 期刊论文
Science, 2020
作者:  Melinda A. Yang;  Xuechun Fan;  Bo Sun;  Chungyu Chen;  Jianfeng Lang;  Ying-Chin Ko;  Cheng-hwa Tsang;  Hunglin Chiu;  Tianyi Wang;  Qingchuan Bao;  Xiaohong Wu;  Mateja Hajdinjak;  Albert Min-Shan Ko;  Manyu Ding;  Peng Cao;  Ruowei Yang;  Feng Liu;  Birgit Nickel;  Qingyan Dai;  Xiaotian Feng;  Lizhao Zhang;  Chengkai Sun;  Chao Ning;  Wen Zeng;  Yongsheng Zhao;  Ming Zhang;  Xing Gao;  Yinqiu Cui;  David Reich;  Mark Stoneking;  Qiaomei Fu
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/21
Precise pitch-scaling of carbon nanotube arrays within three-dimensional DNA nanotrenches 期刊论文
Science, 2020
作者:  Wei Sun;  Jie Shen;  Zhao Zhao;  Noel Arellano;  Charles Rettner;  Jianshi Tang;  Tianyang Cao;  Zhiyu Zhou;  Toan Ta;  Jason K. Streit;  Jeffrey A. Fagan;  Thomas Schaus;  Ming Zheng;  Shu-Jen Han;  William M. Shih;  Hareem T. Maune;  Peng Yin
收藏  |  浏览/下载:7/0  |  提交时间:2020/05/25
Improved protein structure prediction using potentials from deep learning 期刊论文
NATURE, 2020, 577 (7792) : 706-+
作者:  Ma, Runze;  Cao, Duanyun;  Zhu, Chongqin;  Tian, Ye;  Peng, Jinbo;  Guo, Jing;  Chen, Ji;  Li, Xin-Zheng;  Francisco, Joseph S.;  Zeng, Xiao Cheng;  Xu, Li-Mei;  Wang, En-Ge;  Jiang, Ying
收藏  |  浏览/下载:142/0  |  提交时间:2020/07/03

Protein structure prediction can be used to determine the three-dimensional shape of a protein from its amino acid sequence(1). This problem is of fundamental importance as the structure of a protein largely determines its function(2)  however, protein structures can be difficult to determine experimentally. Considerable progress has recently been made by leveraging genetic information. It is possible to infer which amino acid residues are in contact by analysing covariation in homologous sequences, which aids in the prediction of protein structures(3). Here we show that we can train a neural network to make accurate predictions of the distances between pairs of residues, which convey more information about the structure than contact predictions. Using this information, we construct a potential of mean force(4) that can accurately describe the shape of a protein. We find that the resulting potential can be optimized by a simple gradient descent algorithm to generate structures without complex sampling procedures. The resulting system, named AlphaFold, achieves high accuracy, even for sequences with fewer homologous sequences. In the recent Critical Assessment of Protein Structure Prediction(5) (CASP13)-a blind assessment of the state of the field-AlphaFold created high-accuracy structures (with template modelling (TM) scores(6) of 0.7 or higher) for 24 out of 43 free modelling domains, whereas the next best method, which used sampling and contact information, achieved such accuracy for only 14 out of 43 domains. AlphaFold represents a considerable advance in protein-structure prediction. We expect this increased accuracy to enable insights into the function and malfunction of proteins, especially in cases for which no structures for homologous proteins have been experimentally determined(7).


  
MiR-497 similar to 195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1 alpha activity 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Yang, Mi;  Li, Chang-Jun;  Sun, Xi;  Guo, Qi;  Xiao, Ye;  Su, Tian;  Tu, Man-Li;  Peng, Hui;  Lu, Qiong;  Liu, Qing;  He, Hong-Bo;  Jiang, Tie-Jian;  Lei, Min-Xiang;  Wan, Mei;  Cao, Xu;  Luo, Xiang-Hang
收藏  |  浏览/下载:20/0  |  提交时间:2019/11/27
Raman enhancement on ultra-clean graphene quantum dots produced by quasi-equilibrium plasma-enhanced chemical vapor deposition 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Liu, Donghua;  Chen, Xiaosong;  Hu, Yibin;  Sun, Tai;  Song, Zhibo;  Zheng, Yujie;  Cao, Yongbin;  Cai, Zhi;  Cao, Min;  Peng, Lan;  Huang, Yuli;  Du, Lei;  Yang, Wuli;  Chen, Gang;  Wei, Dapeng;  Shen, Andrew Thye;  Wei, Dacheng
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27
Evidence for Majorana bound states in an iron-based superconductor 期刊论文
SCIENCE, 2018, 362 (6412) : 333-335
作者:  Wang, Dongfei;  Kong, Lingyuan;  Fan, Peng;  Chen, Hui;  Zhu, Shiyu;  Liu, Wenyao;  Cao, Lu;  Sun, Yujie;  Du, Shixuan;  Schneeloch, John;  Zhong, Ruidan;  Gu, Genda;  Fu, Liang;  Ding, Hong;  Gao, Hong-Jun
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
Structure of the maize photosystem I supercomplex with light-harvesting complexes I and II 期刊论文
SCIENCE, 2018, 360 (6393) : 1109-1112
作者:  Pan, Xiaowei;  Ma, Jun;  Su, Xiaodong;  Cao, Peng;  Chang, Wenrui;  Liu, Zhenfeng;  Zhang, Xinzheng;  Li, Mei
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27