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Potential for large-scale CO2 removal via enhanced rock weathering with croplands 期刊论文
NATURE, 2020, 583 (7815) : 242-+
作者:  David J. Beerling;  Euripides P. Kantzas;  Mark R. Lomas;  Peter Wade;  Rafael M. Eufrasio;  Phil Renforth;  Binoy Sarkar;  M. Grace Andrews;  Rachael H. James;  Christopher R. Pearce;  Jean-Francois Mercure;  Hector Pollitt;  Philip B. Holden;  Neil R. Edwards;  Madhu Khanna;  Lenny Koh;  Shaun Quegan;  Nick F. Pidgeon;  Ivan A. Janssens;  James Hansen;  Steven A. Banwart
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/14

Enhanced silicate rock weathering (ERW), deployable with croplands, has potential use for atmospheric carbon dioxide (CO2) removal (CDR), which is now necessary to mitigate anthropogenic climate change(1). ERW also has possible co-benefits for improved food and soil security, and reduced ocean acidification(2-4). Here we use an integrated performance modelling approach to make an initial techno-economic assessment for 2050, quantifying how CDR potential and costs vary among nations in relation to business-as-usual energy policies and policies consistent with limiting future warming to 2 degrees Celsius(5). China, India, the USA and Brazil have great potential to help achieve average global CDR goals of 0.5 to 2gigatonnes of carbon dioxide (CO2) per year with extraction costs of approximately US$80-180 per tonne of CO2. These goals and costs are robust, regardless of future energy policies. Deployment within existing croplands offers opportunities to align agriculture and climate policy. However, success will depend upon overcoming political and social inertia to develop regulatory and incentive frameworks. We discuss the challenges and opportunities of ERW deployment, including the potential for excess industrial silicate materials (basalt mine overburden, concrete, and iron and steel slag) to obviate the need for new mining, as well as uncertainties in soil weathering rates and land-ocean transfer of weathered products.


  
The promise and challenge of therapeutic genome editing 期刊论文
NATURE, 2020, 578 (7794) : 229-236
作者:  Zhong, Suijuan;  Ding, Wenyu;  Sun, Le;  Lu, Yufeng;  Dong, Hao;  Fan, Xiaoying;  Liu, Zeyuan;  Chen, Ruiguo;  Zhang, Shu;  Ma, Qiang;  Tang, Fuchou;  Wu, Qian;  Wang, Xiaoqun
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/03

Genome editing, which involves the precise manipulation of cellular DNA sequences to alter cell fates and organism traits, has the potential to both improve our understanding of human genetics and cure genetic disease. Here I discuss the scientific, technical and ethical aspects of using CRISPR (clustered regularly interspaced short palindromic repeats) technology for therapeutic applications in humans, focusing on specific examples that highlight both opportunities and challenges. Genome editing is-or will soon be-in the clinic for several diseases, with more applications under development. The rapid pace of the field demands active efforts to ensure that this breakthrough technology is used responsibly to treat, cure and prevent genetic disease.


  
Mitochondria-Striking a balance between host and endosymbiont 期刊论文
SCIENCE, 2019, 365 (6454) : 655-+
作者:  Youle, Richard J.
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27
Organoids-on-a-chip 期刊论文
SCIENCE, 2019, 364 (6444) : 960-965
作者:  Park, Sunghee Estelle;  Georgescu, Andrei;  Huh, Dongeun
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27
Towards an advanced observation system for the marine Arctic in the framework of the Pan-Eurasian Experiment (PEEX) 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (3) : 1941-1970
作者:  Vihma, Timo;  Uotila, Petteri;  Sandven, Stein;  Pozdnyakov, Dmitry;  Makshtas, Alexander;  Pelyasov, Alexander;  Pirazzini, Roberta;  Danielsen, Finn;  Chalov, Sergey;  Lappalainen, Hanna K.;  Ivanov, Vladimir;  Frolov, Ivan;  Albin, Anna;  Cheng, Bin;  Dobrolyubov, Sergey;  Arkhipkin, Viktor;  Myslenkov, Stanislav;  Petaja, Tuukka;  Kulmala, Markku
收藏  |  浏览/下载:7/0  |  提交时间:2019/04/09
Van der Waals integration before and beyond two-dimensional materials 期刊论文
NATURE, 2019, 567 (7748) : 323-333
作者:  Liu, Yuan;  Huang, Yu;  Duan, Xiangfeng
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
The importance of synthetic chemistry in the pharmaceutical industry 期刊论文
SCIENCE, 2019, 363 (6424) : 244-+
作者:  Campos, Kevin R.;  Coleman, Paul J.;  Alvarez, Juan C.;  Dreher, Spencer D.;  Garbaccio, Robert M.;  Terrett, Nicholas K.;  Tillyer, Richard D.;  Truppo, Matthew D.;  Parmee, Emma R.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Composites with carbon nanotubes and graphene: An outlook 期刊论文
SCIENCE, 2018, 362 (6414) : 547-553
作者:  Kinloch, Ian A.;  Suhr, Jonghwan;  Lou, Jun;  Young, Robert J.;  Ajayan, Pulickel M.
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
CAR T cell immunotherapy for human cancer 期刊论文
SCIENCE, 2018, 359 (6382) : 1361-1365
作者:  June, Carl H.;  39;Connor, Roddy S.
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
Opportunities and challenges in modeling emerging infectious diseases 期刊论文
SCIENCE, 2017, 357 (6347) : 149-152
作者:  Metcalf, C. Jessica E.;  Lessler, Justin
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27