Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aat0805 |
The importance of synthetic chemistry in the pharmaceutical industry | |
Campos, Kevin R.1; Coleman, Paul J.1; Alvarez, Juan C.1; Dreher, Spencer D.1; Garbaccio, Robert M.1; Terrett, Nicholas K.1; Tillyer, Richard D.2; Truppo, Matthew D.2; Parmee, Emma R.1 | |
2019-01-18 | |
发表期刊 | SCIENCE
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ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2019 |
卷号 | 363期号:6424页码:244-+ |
文章类型 | Review |
语种 | 英语 |
国家 | USA |
英文摘要 | Innovations in synthetic chemistry have enabled the discovery of many breakthrough therapies that have improved human health over the past century. In the face of increasing challenges in the pharmaceutical sector, continued innovation in chemistry is required to drive the discovery of the next wave of medicines. Novel synthetic methods not only unlock access to previously unattainable chemical matter, but also inspire new concepts as to how we design and build chemical matter. We identify some of the most important recent advances in synthetic chemistry as well as opportunities at the interface with partner disciplines that are poised to transform the practice of drug discovery and development. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000456140700024 |
WOS关键词 | HIGH-THROUGHPUT EXPERIMENTATION ; CARBOXYLIC-ACIDS ; NATIVE PROTEINS ; DISCOVERY ; PHOTOREDOX ; CATALYSIS ; SITE ; FUNCTIONALIZATION ; FLUORINATION ; PERFORMANCE |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/200564 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Merck & Co Inc, Global Chem, Kenilworth, NJ 07033 USA; 2.Janssen Res & Dev LLC, Spring House, PA 19477 USA |
推荐引用方式 GB/T 7714 | Campos, Kevin R.,Coleman, Paul J.,Alvarez, Juan C.,et al. The importance of synthetic chemistry in the pharmaceutical industry[J]. SCIENCE,2019,363(6424):244-+. |
APA | Campos, Kevin R..,Coleman, Paul J..,Alvarez, Juan C..,Dreher, Spencer D..,Garbaccio, Robert M..,...&Parmee, Emma R..(2019).The importance of synthetic chemistry in the pharmaceutical industry.SCIENCE,363(6424),244-+. |
MLA | Campos, Kevin R.,et al."The importance of synthetic chemistry in the pharmaceutical industry".SCIENCE 363.6424(2019):244-+. |
条目包含的文件 | 条目无相关文件。 |
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