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A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies 期刊论文
SCIENCE, 2019, 365 (6453) : 599-+
作者:  Boettcher, Steffen;  Miller, Peter G.;  Sharma, Rohan;  McConkey, Marie;  Leventhal, Matthew;  Krivtsov, Andrei V.;  Giacomelli, Andrew O.;  Wong, Waihay;  Kim, Jesi;  Chao, Sherry;  Kurppa, Kari J.;  Yang, Xiaoping;  Milenkowic, Kirsten;  Piccioni, Federica;  Root, David E.;  Ruecker, Frank G.;  Flamand, Yael;  Neuberg, Donna;  Lindsley, R. Coleman;  Janne, Pasi A.;  Hahn, William C.;  Jacks, Tyler;  Doehner, Hartmut;  Armstrong, Scott A.;  Ebert, Benjamin L.
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/27
Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent 期刊论文
SCIENCE, 2019, 365 (6449) : 173-+
作者:  Verdugo, Marta Pereira;  Mullin, Victoria E.;  Scheu, Amelie;  Mattiangeli, Valeria;  Daly, Kevin G.;  Delser, Pierpaolo Maisano;  Hare, Andrew J.;  Burger, Joachim;  Collins, Matthew J.;  Kehati, Ron;  Hesse, Paula;  Fulton, Deirdre;  Sauer, Eberhard W.;  Mohaseb, Fatemeh A.;  Davoudi, Hossein;  Khazaeli, Roya;  Lhuillier, Johanna;  Rapin, Claude;  Ebrahimi, Saeed;  Khasanov, Mutalib;  Vahidi, S. M. Farhad;  MacHugh, David E.;  Ertugrul, Okan;  Koukouli-Chrysanthaki, Chaido;  Sampson, Adamantios;  Kazantzis, George;  Kontopoulos, Ioannis;  Bulatovic, Jelena;  Stojanovic, Ivana;  Mikdad, Abdesalam;  Benecke, Norbert;  Linstaedter, Joerg;  Sablin, Mikhail;  Bendrey, Robin;  Gourichon, Lionel;  Arbuckle, Benjamin S.;  Mashkour, Marjan;  Orton, David;  Horwitz, Liora Kolska;  Teasdale, Matthew D.;  Bradley, Daniel G.
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/27
Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice 期刊论文
SCIENCE, 2019, 364 (6437) : 292-+
作者:  Jin, Shuai;  Zong, Yuan;  Gao, Qiang;  Zhu, Zixu;  Wang, Yanpeng;  Qin, Peng;  Liang, Chengzhi;  Wang, Daowen;  Qiu, Jin-Long;  Zhang, Feng;  Gao, Caixia
收藏  |  浏览/下载：8/0  |  提交时间：2019/11/27
Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos 期刊论文
SCIENCE, 2019, 364 (6437) : 289-+
作者:  Zuo, Erwei;  Sun, Yidi;  Wei, Wu;  Yuan, Tanglong;  Ying, Wenqin;  Sun, Hao;  Yuan, Liyun;  Steinmetz, Lars M.;  Li, Yixue;  Yang, Hui
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight 期刊论文
SCIENCE, 2019, 364 (6436) : 144-+
作者:  Garrett-Bakelman, Francine E.;  Darshi, Manjula;  Green, Stefan J.;  Gur, Ruben C.;  Lin, Ling;  Macias, Brandon R.;  McKenna, Miles J.;  Meydan, Cem;  Mishra, Tejaswini;  Nasrini, Jad;  Piening, Brian D.;  Rizzardi, Lindsay F.;  Sharma, Kumar;  Siamwala, Jamila H.;  Taylor, Lynn;  Vitaterna, Martha Hotz;  Afkarian, Maryam;  Afshinnekoo, Ebrahim;  Ahadi, Sara;  Ambati, Aditya;  Arya, Maneesh;  Bezdan, Daniela;  Callahan, Colin M.;  Chen, Songjie;  Choi, Augustine M. K.;  Chlipala, George E.;  Contrepois, Kevin;  Covington, Marisa;  Crucian, Brian E.;  De Vivo, Immaculata;  Dinges, David F.;  Ebert, Douglas J.;  Feinberg, Jason I.;  Gandara, Jorge A.;  George, Kerry A.;  Goutsias, John;  Grills, George S.;  Hargens, Alan R.;  Heer, Martina;  Hillary, Ryan P.;  Hoofnagle, Andrew N.;  Hook, Vivian Y. H.;  Jenkinson, Garrett;  Jiang, Peng;  Keshavarzian, Ali;  Laurie, Steven S.;  Lee-McMullen, Brittany;  Lumpkins, Sarah B.;  MacKay, Matthew;  Maienschein-Cline, Mark G.;  Melnick, Ari M.;  Moore, Tyler M.;  Nakahira, Kiichi;  Patel, Hemal H.;  Pietrzyk, Robert;  Rao, Varsha;  Saito, Rintaro;  Salins, Denis N.;  Schilling, Jan M.;  Sears, Dorothy D.;  Sheridan, Caroline K.;  Stenger, Michael B.;  Tryggvadottir, Rakel;  Urban, Alexander E.;  Vaisar, Tomas;  Van Espen, Benjamin;  Zhang, Jing;  Ziegler, Michael G.;  Zwart, Sara R.;  Charles, John B.;  Kundrot, Craig E.;  Scott, Graham B. I.;  Bailey, Susan M.;  Basner, Mathias;  Feinberg, Andrew P.;  Lee, Stuart M. C.;  Mason, Christopher E.;  Mignot, Emmanuel;  Rana, Brinda K.;  Smith, Scott M.;  Snyder, Michael P.;  Turek, Fred W.
收藏  |  浏览/下载：38/0  |  提交时间：2019/11/27
Convergent regulatory evolution and loss of flight in paleognathous birds 期刊论文
SCIENCE, 2019, 364 (6435) : 74-+
作者:  Sackton, Timothy B.;  Grayson, Phil;  Cloutier, Alison;  Hu, Zhirui;  Liu, Jun S.;  Wheeler, Nicole E.;  Gardner, Paul P.;  Clarke, Julia A.;  Baker, Allan J.;  Clamp, Michele;  Edwards, Scott V.
收藏  |  浏览/下载：90/0  |  提交时间：2019/11/27
Structure of human TFIID and mechanism of TBP loading onto promoter DNA 期刊论文
SCIENCE, 2018, 362 (6421) : 1376-+
作者:  Patel, Avinash B.;  Louder, Robert K.;  Greber, Basil J.;  Grunberg, Sebastian;  Luo, Jie;  Fang, Jie;  Liu, Yutong;  Banish, Jeff;  Hahn, Steve;  Nogales, Eva
收藏  |  浏览/下载：17/0  |  提交时间：2019/11/27
Integrative functional genomic analysis of human brain development and neuropsychiatric risks 期刊论文
SCIENCE, 2018, 362 (6420) : 1264-+
作者:  Li, Mingfeng;  39;Donovan, Michael C.
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/27
Neutral mass spectrometry of virus capsids above 100 megadaltons with nanomechanical resonators 期刊论文
SCIENCE, 2018, 362 (6417) : 918-+
作者:  Dominguez-Medina, Sergio;  Fostner, Shawn;  Defoort, Martial;  Sansa, Marc;  Stark, Ann-Kathrin;  Halim, Mohammad Abdul;  Vernhes, Emeline;  Gely, Marc;  Jourdan, Guillaume;  Alava, Thomas;  Boulanger, Pascale;  Masselon, Christophe;  Hentz, Sebastien
收藏  |  浏览/下载：4/0  |  提交时间：2019/11/27
Dynamic DNA methylation: In the right place at the right time 期刊论文
SCIENCE, 2018, 361 (6409) : 1336-1340
作者:  Luo, Chongyuan;  Hajkova, Petra;  Ecker, Joseph R.
收藏  |  浏览/下载：1/0  |  提交时间：2019/11/27