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Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice 期刊论文
Science, 2021
作者:  David R. Martinez;  Alexandra Schäfer;  Sarah R. Leist;  Gabriela De la Cruz;  Ande West;  Elena N. Atochina-Vasserman;  Lisa C. Lindesmith;  Norbert Pardi;  Robert Parks;  Maggie Barr;  Dapeng Li;  Boyd Yount;  Kevin O. Saunders;  Drew Weissman;  Barton F. Haynes;  Stephanie A. Montgomery;  Ralph S. Baric
收藏  |  浏览/下载:12/0  |  提交时间:2021/08/30
Changing climate associated with the range‐wide decline of an estuarine finfish 期刊论文
Global Change Biology, 2021
作者:  Kenneth A. Erickson;  Joe West;  Michael A. Dance;  Troy M. Farmer;  Joseph C. Ballenger;  Stephen R. Midway
收藏  |  浏览/下载:8/0  |  提交时间:2021/03/29
Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice 期刊论文
Science, 2021
作者:  Alexander A. Cohen;  Priyanthi N. P. Gnanapragasam;  Yu E. Lee;  Pauline R. Hoffman;  Susan Ou;  Leesa M. Kakutani;  Jennifer R. Keeffe;  Hung-Jen Wu;  Mark Howarth;  Anthony P. West;  Christopher O. Barnes;  Michel C. Nussenzweig;  Pamela J. Bjorkman
收藏  |  浏览/下载:14/0  |  提交时间:2021/02/17
Integrated borehole, radar, and seismic velocity analysis reveals dynamic spatial variations within a firn aquifer in southeast Greenland 期刊论文
Geophysical Research Letters, 2020
作者:  S. F. Killingbeck;  N. C. Schmerr;  L. N. Montgomery;  A. D. Booth;  P. W. Livermore;  J. Guandique;  O. L. Miller;  S. Burdick;  R. R. Forster;  L. Koenig;  A. Legchenko;  S. Ligtenberg;  C. Miè;  ge;  D. K. Solomon;  L. J. West
收藏  |  浏览/下载:5/0  |  提交时间:2020/09/14
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants 期刊论文
Science, 2020
作者:  Siwei Zhang;  Hanwen Zhang;  Yifan Zhou;  Min Qiao;  Siming Zhao;  Alena Kozlova;  Jianxin Shi;  Alan R. Sanders;  Gao Wang;  Kaixuan Luo;  Subhajit Sengupta;  Siobhan West;  Sheng Qian;  Michael Streit;  Dimitrios Avramopoulos;  Chad A. Cowan;  Mengjie Chen;  Zhiping P. Pang;  Pablo V. Gejman;  Xin He;  Jubao Duan
收藏  |  浏览/下载:10/0  |  提交时间:2020/08/09
A remnant planetary core in the hot-Neptune desert 期刊论文
NATURE, 2020, 583 (7814) : 39-+
作者:  David J. Armstrong;  Thé;  o A. Lopez;  Vardan Adibekyan;  Richard A. Booth;  Edward M. Bryant;  Karen A. Collins;  Magali Deleuil;  Alexandre Emsenhuber;  Chelsea X. Huang;  George W. King;  Jorge Lillo-Box;  Jack J. Lissauer;  Elisabeth Matthews;  Olivier Mousis;  Louise D. Nielsen;  Hugh Osborn;  Jon Otegi;  Nuno C. Santos;  ;  rgio G. Sousa;  Keivan G. Stassun;  Dimitri Veras;  Carl Ziegler;  Jack S. Acton;  Jose M. Almenara;  David R. Anderson;  David Barrado;  Susana C. C. Barros;  Daniel Bayliss;  Claudia Belardi;  Francois Bouchy;  ;  sar Briceñ;  o;  Matteo Brogi;  David J. A. Brown;  Matthew R. Burleigh;  Sarah L. Casewell;  Alexander Chaushev;  David R. Ciardi;  Kevin I. Collins;  Knicole D. Coló;  n;  Benjamin F. Cooke;  Ian J. M. Crossfield;  Rodrigo F. Dí;  az;  Elisa Delgado Mena;  Olivier D. S. Demangeon;  Caroline Dorn;  Xavier Dumusque;  Philipp Eigmü;  ller;  Michael Fausnaugh;  Pedro Figueira;  Tianjun Gan;  Siddharth Gandhi;  Samuel Gill;  Erica J. Gonzales;  Michael R. Goad;  Maximilian N. Gü;  nther;  Ravit Helled;  Saeed Hojjatpanah;  Steve B. Howell;  James Jackman;  James S. Jenkins;  Jon M. Jenkins;  Eric L. N. Jensen;  Grant M. Kennedy;  David W. Latham;  Nicholas Law;  Monika Lendl;  Michael Lozovsky;  Andrew W. Mann;  Maximiliano Moyano;  James McCormac;  Farzana Meru;  Christoph Mordasini;  Ares Osborn;  Don Pollacco;  Didier Queloz;  Liam Raynard;  George R. Ricker;  Pamela Rowden;  Alexandre Santerne;  Joshua E. Schlieder;  Sara Seager;  Lizhou Sha;  Thiam-Guan Tan;  Rosanna H. Tilbrook;  Eric Ting;  Sté;  phane Udry;  Roland Vanderspek;  Christopher A. Watson;  Richard G. West;  Paul A. Wilson;  Joshua N. Winn;  Peter Wheatley;  Jesus Noel Villasenor;  Jose I. Vines;  Zhuchang Zhan
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/06

The interiors of giant planets remain poorly understood. Even for the planets in the Solar System, difficulties in observation lead to large uncertainties in the properties of planetary cores. Exoplanets that have undergone rare evolutionary processes provide a route to understanding planetary interiors. Planets found in and near the typically barren hot-Neptune '  desert'  (1,2)(a region in mass-radius space that contains few planets) have proved to be particularly valuable in this regard. These planets include HD149026b(3), which is thought to have an unusually massive core, and recent discoveries such as LTT9779b(4)and NGTS-4b(5), on which photoevaporation has removed a substantial part of their outer atmospheres. Here we report observations of the planet TOI-849b, which has a radius smaller than Neptune'  s but an anomalously large mass of39.1-2.6+2.7Earth masses and a density of5.2-0.8+0.7grams per cubic centimetre, similar to Earth'  s. Interior-structure models suggest that any gaseous envelope of pure hydrogen and helium consists of no more than3.9-0.9+0.8 per cent of the total planetary mass. The planet could have been a gas giant before undergoing extreme mass loss via thermal self-disruption or giant planet collisions, or it could have avoided substantial gas accretion, perhaps through gap opening or late formation(6). Although photoevaporation rates cannot account for the mass loss required to reduce a Jupiter-like gas giant, they can remove a small (a few Earth masses) hydrogen and helium envelope on timescales of several billion years, implying that any remaining atmosphere on TOI-849b is likely to be enriched by water or other volatiles from the planetary interior. We conclude that TOI-849b is the remnant core of a giant planet.


Observations of TOI-849b reveal a radius smaller than Neptune'  s but a large mass of about 40 Earth masses, indicating that the planet is the remnant core of a gas giant.


  
Principles for knowledge co-production in sustainability research 期刊论文
NATURE SUSTAINABILITY, 2020, 3 (3) : 182-190
作者:  Norstrom, Albert, V;  Cvitanovic, Christopher;  Lof, Marie F.;  West, Simon;  Wyborn, Carina;  Balvanera, Patricia;  Bednarek, Angela T.;  Bennett, Elena M.;  Biggs, Reinette;  de Bremond, Ariane;  Campbell, Bruce M.;  Canadell, Josep G.;  Carpenter, Stephen R.;  Folke, Carl;  Fulton, Elizabeth A.;  Gaffney, Owen;  Gelcich, Stefan;  Jouffray, Jean-Baptiste;  Leach, Melissa;  Le Tissier, Martin;  Martin-Lopez, Berta;  Louder, Elena;  Loutre, Marie-France;  Meadow, Alison M.;  Nagendra, Harini;  Payne, Davnah;  Peterson, Garry D.;  Reyers, Belinda;  Scholes, Robert;  Speranza, Chinwe Ifejika;  Spierenburg, Marja;  Stafford-Smith, Mark;  Tengo, Maria;  van der Hel, Sandra;  van Putten, Ingrid;  Osterblom, Henrik
收藏  |  浏览/下载:17/0  |  提交时间:2020/05/13
Dust and Snow Cover on Saturn's Icy Moons 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2019
作者:  Le Gall, A.;  West, R. D.;  Bonnefoy, L. E.
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27
Archaeological assessment reveals Earth's early transformation through land use 期刊论文
SCIENCE, 2019, 365 (6456) : 897-+
作者:  Stephens, Lucas;  Fuller, Dorian;  Boivin, Nicole;  Rick, Torben;  Gauthier, Nicolas;  Kay, Andrea;  Marwick, Ben;  Armstrong, Chelsey Geralda Denise;  Barton, C. Michael;  Denham, Tim;  Douglass, Kristina;  Driver, Jonathan;  Janz, Lisa;  Roberts, Patrick;  Rogers, J. Daniel;  Thakar, Heather;  Altaweel, Mark;  Johnson, Amber L.;  Sampietro Vattuone, Maria Marta;  Aldenderfer, Mark;  Archila, Sonia;  Artioli, Gilberto;  Bale, Martin T.;  Beach, Timothy;  Borrell, Ferran;  Braje, Todd;  Buckland, Philip I.;  Jimenez Cano, Nayeli Guadalupe;  Capriles, Jose M.;  Diez Castillo, Agustin;  Cilingiroglu, Ciler;  Cleary, Michelle Negus;  Conolly, James;  Coutros, Peter R.;  Covey, R. Alan;  Cremaschi, Mauro;  Crowther, Alison;  Der, Lindsay;  di Lernia, Savino;  Doershuk, John F.;  Doolittle, William E.;  Edwards, Kevin J.;  Erlandson, Jon M.;  Evans, Damian;  Fairbairn, Andrew;  Faulkner, Patrick;  Feinman, Gary;  Fernandes, Ricardo;  Fitzpatrick, Scott M.;  Fyfe, Ralph;  Garcea, Elena;  Goldstein, Steve;  Goodman, Reed Charles;  Guedes, Jade Dalpoim;  Herrmann, Jason;  Hiscock, Peter;  Hommel, Peter;  Horsburgh, K. Ann;  Hritz, Carrie;  Ives, John W.;  Junno, Aripekka;  Kahn, Jennifer G.;  Kaufman, Brett;  Kearns, Catherine;  Kidder, Tristram R.;  Lanoe, Francois;  Lawrence, Dan;  Lee, Gyoung-Ah;  Levin, Maureece J.;  Lindskoug, Henrik B.;  Antonio Lopez-Saez, Jose;  Macrae, Scott;  Marchant, Rob;  Marston, John M.;  McClure, Sarah;  Mccoy, Mark D.;  Miller, Alicia Ventresca;  Morrison, Michael;  Matuzeviciute, Giedre Motuzaite;  Mueller, Johannes;  Nayak, Ayushi;  Noerwidi, Sofwan;  Peres, Tanya M.;  Peterson, Christian E.;  Proctor, Lucas;  Randall, Asa R.;  Renette, Steve;  Schug, Gwen Robbins;  Ryzewski, Krysta;  Saini, Rakesh;  Scheinsohn, Vivian;  Schmidt, Peter;  Sebillaud, Pauline;  Seitsonen, Oula;  Simpson, Ian A.;  Soltysiak, Arkadiusz;  Speakman, Robert J.;  Spengler, Robert N.;  Steffen, Martina L.;  Storozum, Michael J.;  Strickland, Keir M.;  Thompson, Jessica;  Thurston, T. L.;  Ulm, Sean;  Ustunkaya, M. Cemre;  Welker, Martin H.;  West, Catherine;  Williams, Patrick Ryan;  Wright, David K.;  Wright, Nathan;  Zahir, Muhammad;  Zerboni, Andrea;  Beaudoin, Ella;  Garcia, Santiago Munevar;  Powell, Jeremy;  Thornton, Alexa;  Kaplan, Jed O.;  Gaillard, Marie-Jose;  Goldewijk, Kees Klein;  Ellis, Erle
收藏  |  浏览/下载:56/0  |  提交时间:2019/11/27
Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  King, Liam B.;  West, Brandyn R.;  Moyer, Crystal L.;  Gilchuk, Pavlo;  Flyak, Andrew;  Ilinykh, Philipp A.;  Bombardi, Robin;  Hui, Sean;  Huang, Kai;  Bukreyev, Alexander;  Crowe, James E., Jr.;  Saphire, Erica Ollmann
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27