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A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage (vol 551, pg 629, 2017) 期刊论文
NATURE, 2020, 580 (7802) : E5-E5
作者:  Lu, Zhihao;  Zou, Jianling;  Li, Shuang;  Topper, Michael J.;  Tao, Yong;  Zhang, Hao;  Jiao, Xi;  Xie, Wenbing;  Kong, Xiangqian;  Vaz, Michelle;  Li, Huili;  Cai, Yi;  Xia, Limin;  Huang, Peng;  Rodgers, Kristen;  Lee, Beverly;  Riemer, Joanne B.;  Day, Chi-Ping;  Yen, Ray-Whay Chiu;  Cui, Ying;  Wang, Yujiao;  Wang, Yanni;  Zhang, Weiqiang;  Easwaran, Hariharan;  Hulbert, Alicia;  Kim, KiBem;  Juergens, Rosalyn A.;  Yang, Stephen C.;  Battafarano, Richard J.;  Bush, Errol L.;  Broderick, Stephen R.;  Cattaneo, Stephen M.;  Brahmer, Julie R.;  Rudin, Charles M.;  Wrangle, John;  Mei, Yuping;  Kim, Young J.;  Zhang, Bin;  Wang, Ken Kang-Hsin;  Forde, Patrick M.;  Margolick, Joseph B.;  Nelkin, Barry D.;  Zahnow, Cynthia A.;  Pardoll, Drew M.;  Housseau, Franck;  Baylin, Stephen B.;  Shen, Lin;  Brock, Malcolm V.
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/03
Nightside condensation of iron in an ultrahot giant exoplanet 期刊论文
NATURE, 2020, 580 (7805) : 597-+
作者:  Lu, Zhihao;  Zou, Jianling;  Li, Shuang;  Topper, Michael J.;  Tao, Yong;  Zhang, Hao;  Jiao, Xi;  Xie, Wenbing;  Kong, Xiangqian;  Vaz, Michelle;  Li, Huili;  Cai, Yi;  Xia, Limin;  Huang, Peng;  Rodgers, Kristen;  Lee, Beverly;  Riemer, Joanne B.;  Day, Chi-Ping;  Yen, Ray-Whay Chiu;  Cui, Ying;  Wang, Yujiao;  Wang, Yanni;  Zhang, Weiqiang;  Easwaran, Hariharan;  Hulbert, Alicia;  Kim, KiBem;  Juergens, Rosalyn A.;  Yang, Stephen C.;  Battafarano, Richard J.;  Bush, Errol L.;  Broderick, Stephen R.;  Cattaneo, Stephen M.;  Brahmer, Julie R.;  Rudin, Charles M.;  Wrangle, John;  Mei, Yuping;  Kim, Young J.;  Zhang, Bin;  Wang, Ken Kang-Hsin;  Forde, Patrick M.;  Margolick, Joseph B.;  Nelkin, Barry D.;  Zahnow, Cynthia A.;  Pardoll, Drew M.;  Housseau, Franck;  Baylin, Stephen B.;  Shen, Lin;  Brock, Malcolm V.
收藏  |  浏览/下载：58/0  |  提交时间：2020/07/03

Ultrahot giant exoplanets receive thousands of times Earth'  s insolation(1,2). Their high-temperature atmospheres (greater than 2,000 kelvin) are ideal laboratories for studying extreme planetary climates and chemistry(3-5). Daysides are predicted to be cloud-free, dominated by atomic species(6) and much hotter than nightsides(5,7,8). Atoms are expected to recombine into molecules over the nightside(9), resulting in different day and night chemistries. Although metallic elements and a large temperature contrast have been observed(10-14), no chemical gradient has been measured across the surface of such an exoplanet. Different atmospheric chemistry between the day-to-night ('  evening'  ) and night-to-day ('  morning'  ) terminators could, however, be revealed as an asymmetric absorption signature during transit(4,7,15). Here we report the detection of an asymmetric atmospheric signature in the ultrahot exoplanet WASP-76b. We spectrally and temporally resolve this signature using a combination of high-dispersion spectroscopy with a large photon-collecting area. The absorption signal, attributed to neutral iron, is blueshifted by -11 +/- 0.7 kilometres per second on the trailing limb, which can be explained by a combination of planetary rotation and wind blowing from the hot dayside(16). In contrast, no signal arises from the nightside close to the morning terminator, showing that atomic iron is not absorbing starlight there. We conclude that iron must therefore condense during its journey across the nightside.


Absorption lines of iron in the dayside atmosphere of an ultrahot giant exoplanet disappear after travelling across the nightside, showing that the iron has condensed during its travel.


  
Modular and tunable biological feedback control using a de novo protein switch (vol 572, pg 265, 2019) 期刊论文
NATURE, 2020, 579 (7798) : E8-E8
作者:  Christodoulou, Constantina;  Spencer, Joel A.;  Yeh, Shu-Chi A.;  Turcotte, Raphael;  Kokkaliaris, Konstantinos D.;  Panero, Riccardo;  Ramos, Azucena;  Guo, Guoji;  Seyedhassantehrani, Negar;  Esipova, Tatiana V.;  Vinogradov, Sergei A.;  Rudzinskas, Sarah;  Zhang, Yi;  Perkins, Archibald S.;  Orkin, Stuart H.;  Calogero, Raffaele A.;  Schroeder, Timm;  Lin, Charles P.;  Camargo, Fernando D.
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/03
Synthesis and observation of non-Abelian gauge fields in real space 期刊论文
SCIENCE, 2019, 365 (6457) : 1021-+
作者:  Yang, Yi;  Peng, Chao;  Zhu, Di;  Buljan, Hrvoje;  Joanmopoulos, John D.;  Zhen, Bo;  Soljacic, Matin
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/27
Bright and photostable chemigenetic indicators for extended in vivo voltage imaging 期刊论文
SCIENCE, 2019, 365 (6454) : 699-+
作者:  Abdelfattah, Ahmed S.;  Kawashima, Takashi;  Singh, Amrita;  Novak, Ondrej;  Liu, Hui;  Shuai, Yichun;  Huang, Yi-Chieh;  Campagnola, Luke;  Seeman, Stephanie C.;  Yu, Jianing;  Zheng, Jihong;  Grimm, Jonathan B.;  Patel, Ronak;  Friedrich, Johannes;  Mensh, Brett D.;  Paninski, Liam;  Macklin, John J.;  Murphy, Gabe J.;  Podgorski, Kaspar;  Lin, Bei-Jung;  Chen, Tsai-Wen;  Turner, Glenn C.;  Liu, Zhe;  Koyama, Minoru;  Svoboda, Karel;  Ahrens, Misha B.;  Lavis, Luke D.;  Schreiter, Eric R.
收藏  |  浏览/下载：20/0  |  提交时间：2019/11/27
Structure and dynamics of the active human parathyroid hormone receptor-1 期刊论文
SCIENCE, 2019, 364 (6436) : 148-+
作者:  Zhao, Li-Hua;  Ma, Shanshan;  Sutkeviciute, Ieva;  Shen, Dan-Dan;  Zhou, X. Edward;  de Waal, Parker W.;  Li, Chen-Yao;  Kang, Yanyong;  Clark, Lisa J.;  Jean-Alphonse, Frederic G.;  White, Alex D.;  Yang, Dehua;  Dai, Antao;  Cai, Xiaoqing;  Chen, Jian;  Li, Cong;  Jiang, Yi;  Watanabe, Tomoyuki;  Gardella, Thomas J.;  Melcher, Karsten;  Wang, Ming-Wei;  Vilardaga, Jean-Pierre;  Xu, H. Eric;  Zhang, Yan
收藏  |  浏览/下载：15/0  |  提交时间：2019/11/27
A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme 期刊论文
SCIENCE, 2018, 361 (6407) : 1098-+
作者:  Mirts, Evan N.;  Petrik, Igor D.;  Hosseinzadeh, Parisa;  Nilges, Mark J.;  Lu, Yi
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/27
Genomic and epidemiological monitoring of yellow fever virus transmission potential 期刊论文
SCIENCE, 2018, 361 (6405) : 894-+
作者:  Faria, N. R.;  Kraemer, M. U. G.;  Hill, S. C.;  de Jesus, J. Goes;  Aguiar, R. S.;  Iani, F. C. M.;  Xavier, J.;  Quick, J.;  du Plessis, L.;  Dellicour, S.;  Theze, J.;  Carvalho, R. D. O.;  Baele, G.;  Wu, C. -H.;  Silveira, P. P.;  Arruda, M. B.;  Pereira, M. A.;  Pereira, G. C.;  Lourenco, J.;  Obolski, U.;  Abade, L.;  Vasylyeva, T. I.;  Giovanetti, M.;  Yi, D.;  Weiss, D. J.;  Wint, G. R. W.;  Shearer, F. M.;  Funk, S.;  Nikolay, B.;  Fonseca, V.;  Adelino, T. E. R.;  Oliveira, M. A. A.;  Silva, M. V. F.;  Sacchetto, L.;  Figueiredo, P. O.;  Rezende, I. M.;  Mello, E. M.;  Said, R. F. C.;  Santos, D. A.;  Ferraz, M. L.;  Brito, M. G.;  Santana, L. F.;  Menezes, M. T.;  Brindeiro, R. M.;  Tanuri, A.;  dos Santos, F. C. P.;  Cunha, M. S.;  Nogueira, J. S.;  Rocco, I. M.;  da Costa, A. C.;  Komninakis, S. C. V.;  Azevedo, V.;  Chieppe, A. O.;  Araujo, E. S. M.;  Mendonca, M. C. L.;  dos Santos, C. C.;  dos Santos, C. D.;  Mares-Guia, A. M.;  Nogueira, R. M. R.;  Sequeira, P. C.;  Abreu, R. G.;  Garcia, M. H. O.;  Abreu, A. L.;  Okumoto, O.;  Kroon, E. G.;  de Albuquerque, C. F. C.;  Lewandowski, K.;  Pullan, S. T.;  Carroll, M.;  de Oliveira, T.;  Sabino, E. C.;  Souza, R. P.;  Suchard, M. A.;  Lemey, P.;  Trindade, G. S.;  Drumond, B. P.;  Filippis, A. M. B.;  Loman, N. J.;  Cauchemez, S.;  Alcantara, L. C. J.;  Pybus, O. G.
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/27
A generative vision model that trains with high data efficiency and breaks text-based CAPTCHAs 期刊论文
SCIENCE, 2017, 358 (6368)
作者:  George, Dileep;  Lehrach, Wolfgang;  Kansky, Ken;  Lazaro-Gredilla, Miguel;  Laan, Christopher;  Marthi, Bhaskara;  Lou, Xinghua;  Meng, Zhaoshi;  Liu, Yi;  Wang, Huayan;  Lavin, Alex;  Phoenix, D. Scott
收藏  |  浏览/下载：6/0  |  提交时间：2019/11/27
Loci associated with skin pigmentation identified in African populations 期刊论文
SCIENCE, 2017, 358 (6365) : 887-+
作者:  Crawford, Nicholas G.;  Kelly, Derek E.;  Hansen, Matthew E. B.;  Beltrame, Marcia H.;  Fan, Shaohua;  Bowman, Shanna L.;  Jewett, Ethan;  Ranciaro, Alessia;  Thompson, Simon;  Lo, Yancy;  Pfeifer, Susanne P.;  Jensen, Jeffrey D.;  Campbell, Michael C.;  Beggs, William;  Hormozdiari, Farhad;  Mpoloka, Sununguko Wata;  Mokone, Gaonyadiwe George;  Nyambo, Thomas;  Meskel, Dawit Wolde;  Belay, Gurja;  Haut, Jake;  Rothschild, Harriet;  Zon, Leonard;  Zhou, Yi;  Kovacs, Michael A.;  Xu, Mai;  Zhang, Tongwu;  Bishop, Kevin;  Sinclair, Jason;  Rivas, Cecilia;  Elliot, Eugene;  Choi, Jiyeon;  Li, Shengchao A.;  Hicks, Belynda;  Burgess, Shawn;  Abnet, Christian;  Watkins-Chow, Dawn E.;  Oceana, Elena;  Song, Yun S.;  Eskin, Eleazar;  Brown, Kevin M.;  Marks, Michael S.;  Loftus, Stacie K.;  Pavan, William J.;  Yeager, Meredith;  Chanock, Stephen;  Tishkoff, Sarah A.
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/27