Genomic and epidemiological monitoring of yellow fever virus transmission potential

doi:10.1126/science.aat7115

GSTDTAP > 地球科学

DOI	10.1126/science.aat7115
	Genomic and epidemiological monitoring of yellow fever virus transmission potential
	Faria, N. R.1; Kraemer, M. U. G.1,2,3; Hill, S. C.1; de Jesus, J. Goes 4; Aguiar, R. S.5; Iani, F. C. M.6,7; Xavier, J.4; Quick, J.8; du Plessis, L.1; Dellicour, S.9; Theze, J.1; Carvalho, R. D. O.7; Baele, G.9; Wu, C. -H.10; Silveira, P. P.5; Arruda, M. B.5; Pereira, M. A.6; Pereira, G. C.6; Lourenco, J.1; Obolski, U.1; Abade, L.1,11; Vasylyeva, T. I.1; Giovanetti, M.4,7; Yi, D.12; Weiss, D. J.13; Wint, G. R. W.1; Shearer, F. M.13; Funk, S.14; Nikolay, B.15,16,17; Fonseca, V.7,18; Adelino, T. E. R.6; Oliveira, M. A. A.6; Silva, M. V. F.6; Sacchetto, L.7; Figueiredo, P. O.7; Rezende, I. M.7; Mello, E. M.7; Said, R. F. C.19; Santos, D. A.19; Ferraz, M. L.19; Brito, M. G.19; Santana, L. F.19; Menezes, M. T.5; Brindeiro, R. M.5; Tanuri, A.5; dos Santos, F. C. P.20; Cunha, M. S.20; Nogueira, J. S.20; Rocco, I. M.20; da Costa, A. C.21,22; Komninakis, S. C. V.23,24; Azevedo, V.7; Chieppe, A. O.25; Araujo, E. S. M.4; Mendonca, M. C. L.4; dos Santos, C. C.4; dos Santos, C. D.4; Mares-Guia, A. M.4; Nogueira, R. M. R.4; Sequeira, P. C.4; Abreu, R. G.26; Garcia, M. H. O.26; Abreu, A. L.27; Okumoto, O.27; Kroon, E. G.7; de Albuquerque, C. F. C.28; Lewandowski, K.29; Pullan, S. T.29; Carroll, M.30; de Oliveira, T.4,18,31; Sabino, E. C.21,22; Souza, R. P.20; Suchard, M. A.32,33; Lemey, P.9; Trindade, G. S.7; Drumond, B. P.7; Filippis, A. M. B.4; Loman, N. J.8; Cauchemez, S.15,16,17; Alcantara, L. C. J.4,7; Pybus, O. G.1
	2018-08-31
发表期刊	SCIENCE
ISSN	0036-8075
EISSN	1095-9203
出版年	2018
卷号	361 期号:6405 页码:894-+
文章类型	Article
语种	英语
国家	England; USA; Brazil; Belgium; France; South Africa
英文摘要	The yellow fever virus (YFV) epidemic in Brazil is the largest in decades. The recent discovery of YFV in Brazilian Aedes species mosquitos highlights a need to monitor the risk of reestablishment of urban YFV transmission in the Americas. We use a suite of epidemiological, spatial, and genomic approaches to characterize YFV transmission. We show that the age and sex distribution of human cases is characteristic of sylvatic transmission. Analysis of YFV cases combined with genomes generated locally reveals an early phase of sylvatic YFV transmission and spatial expansion toward previously YFV-free areas, followed by a rise in viral spillover to humans in late 2016. Our results establish a framework for monitoring YFV transmission in real time that will contribute to a global strategy to eliminate future YFV epidemics.
领域	地球科学 ; 气候变化 ; 资源环境
收录类别	SCI-E
WOS记录号	WOS:000443547000033
WOS关键词	SPREAD ; BRAZIL ; ANGOLA
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/199476
专题	地球科学资源环境科学气候变化
作者单位	1.Univ Oxford, Dept Zool, Oxford, England; 2.Boston Childrens Hosp, Computat Epidemiol Lab, Boston, MA USA; 3.Harvard Med Sch, Dept Pediat, Boston, MA USA; 4.Fiocruz MS, Inst Oswaldo Cruz, Lab Flavivirus, Rio De Janeiro, Brazil; 5.Univ Fed Rio de Janeiro, Inst Biol, Dept Genet, Mol Virol Lab, Rio De Janeiro, Brazil; 6.FUNED, Inst Octavio Magalhaes, Lab Cent Saude Publ, Belo Horizonte, MG, Brazil; 7.Univ Fed Minas Gerais, Inst Ciencias Biol, Belo Horizonte, MG, Brazil; 8.Univ Birmingham, Inst Microbiol & Infect, Birmingham, W Midlands, England; 9.Katholieke Univ Leuven, Dept Microbiol & Immunol, Rega Inst, Leuven, Belgium; 10.Univ Oxford, Dept Stat, Oxford, England; 11.Univ Oxford, Global Hlth Network, Oxford, England; 12.Harvard Univ, Dept Stat, Cambridge, MA 02138 USA; 13.Univ Oxford, Nuffield Dept Med, Big Data Inst, Malaria Atlas Project, Oxford, England; 14.London Sch Hyg & Trop Med, Fac Epidemiol & Populat Hlth, London, England; 15.Inst Pasteur, Math Modelling Infect Dis, Paris, France; 16.Inst Pasteur, Ctr Bioinformat, Paris, France; 17.Inst Pasteur, CNRS, Genom Evolut Modelisat & Sante UMR2000, Paris, France; 18.Univ KwaZulu Natal, KwaZulu Natal Res Innovat & Sequencing Platform K, Sch Lab Med & Med Sci, Durban, South Africa; 19.Secretaria Estado Saude Minas Gerais, Belo Horizonte, MG, Brazil; 20.Adolfo Lutz Inst, Nucleo Doencas Transmissao Vetorial, Sao Paulo, Brazil; 21.Univ Sao Paulo, Inst Trop Med, Sao Paulo, Brazil; 22.Univ Sao Paulo, Fac Med, Sao Paulo, Brazil; 23.Univ Fed Sao Paulo, Retrovirol Lab, Sao Paulo, Brazil; 24.Sch Med ABC FMABC, Clin Immunol Lab, Santo Andre, SP, Brazil; 25.Coordenacao Vigilancia Epidemiol Estado Rio de Ja, Rio De Janeiro, Brazil; 26.Minist Saude, Dept Vigilancia Doencas Transmissiveis, Secretaria Vigilancia Saude, Brasilia, DF, Brazil; 27.Minist Saude, Secretaria Vigilancia Saude, Coordenacao Geral Labs Saude Publ, Brasilia, DF, Brazil; 28.OMS, OPAS, Brasilia, DF, Brazil; 29.Publ Hlth England, Natl Infect Serv, Salisbury, Wilts, England; 30.Publ Hlth England, NIHR HPRU Emerging & Zoonot Infect, London, England; 31.Ctr AIDS Programme Res South Africa CAPRISA, Durban, South Africa; 32.Univ Calif Los Angeles, Dept Biostat, Fielding Sch Publ Hlth, Los Angeles, CA USA; 33.Univ Calif Los Angeles, David Geffen Sch Med, Dept Biomath & Human Genet, Los Angeles, CA 90095 USA
推荐引用方式 GB/T 7714	Faria, N. R.,Kraemer, M. U. G.,Hill, S. C.,et al. Genomic and epidemiological monitoring of yellow fever virus transmission potential[J]. SCIENCE,2018,361(6405):894-+.
APA	Faria, N. R..,Kraemer, M. U. G..,Hill, S. C..,de Jesus, J. Goes.,Aguiar, R. S..,...&Pybus, O. G..(2018).Genomic and epidemiological monitoring of yellow fever virus transmission potential.SCIENCE,361(6405),894-+.
MLA	Faria, N. R.,et al."Genomic and epidemiological monitoring of yellow fever virus transmission potential".SCIENCE 361.6405(2018):894-+.