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Unified prebiotically plausible synthesis of pyrimidine and purine RNA ribonucleotides 期刊论文
SCIENCE, 2019, 366 (6461) : 76-+
作者:  Becker, Sidney;  Feldmann, Jonas;  Wiedemann, Stefan;  Okamura, Hidenori;  Schneider, Christina;  Iwan, Katharina;  Crisp, Antony;  Rossa, Martin;  Amatov, Tynchtyk;  Carell, Thomas
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
TIR domains of plant immune receptors are NAD(+)-cleaving enzymes that promote cell death 期刊论文
SCIENCE, 2019, 365 (6455) : 799-+
作者:  Wan, Li;  Essuman, Kow;  Anderson, Ryan G.;  Sasaki, Yo;  Monteiro, Freddy;  Chung, Eui-Hwan;  Nishimura, Erin Osborne;  DiAntonio, Aaron;  Milbrandt, Jeffrey;  Dangl, Jeffery L.;  Nishimura, Marc T.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
NAD(+) cleavage activity by animal an plant TIR domains in cell death pathways 期刊论文
SCIENCE, 2019, 365 (6455) : 793-+
作者:  Horsefield, Shane;  Burdett, Hayden;  Zhang, Xiaoxiao;  Manik, Mohammad K.;  Shi, Yun;  Chen, Jian;  Qi, Tiancong;  Gilley, Jonathan;  Lai, Jhih-Siang;  Rank, Maxwell X.;  Casey, Lachlan W.;  Gu, Weixi;  Ericsson, Daniel J.;  Foley, Gabriel;  Hughes, Robert O.;  Bosanac, Todd;  von Itzstein, Mark;  Rathjen, John P.;  Nanson, Jeffrey D.;  Boden, Mikael;  Dry, Ian B.;  Williams, Simon J.;  Staskawicz, Brian J.;  Coleman, Michael P.;  Ve, Thomas;  Dodds, Peter N.;  Kobe, Bostjan
收藏  |  浏览/下载:16/0  |  提交时间:2019/11/27
Structures and gating mechanism of human TRPM2 期刊论文
SCIENCE, 2018, 362 (6421) : 1377-+
作者:  Wang, Longfei;  Fu, Tian-Min;  Zhou, Yiming;  Xia, Shiyu;  Greka, Anna;  Wu, Hao
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/27
Poly(ADP-ribose) drives pathologic alpha-synuclein neurodegeneration in Parkinson's disease 期刊论文
SCIENCE, 2018, 362 (6414) : 557-+
作者:  Kam, Tae-In;  Mao, Xiaobo;  Park, Hyejin;  Chou, Shih-Ching;  Karuppagounder, Senthilkumar S.;  Umanah, George Essien;  Yun, Seung Pil;  Brahmachari, Saurav;  Panicker, Nikhil;  Chen, Rong;  Andrabi, Shaida A.;  Qi, Chen;  Poirier, Guy G.;  Pletnikova, Olga;  Troncoso, Juan C.;  Bekris, Lynn M.;  Leverenz, James B.;  Pantelyat, Alexander;  Ko, Han Seok;  Rosenthal, Liana S.;  Dawson, Ted M.;  Dawson, Valina L.
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
Metabolic regulation of transcription through compartmentalized NAD(+) biosynthesis 期刊论文
SCIENCE, 2018, 360 (6389)
作者:  Ryu, Keun Woo;  Nandu, Tulip;  Kim, Jiyeon;  Challa, Sridevi;  DeBerardinis, Ralph J.;  Kraus, W. Lee
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
AGING A conserved NAD(+) binding pocket that regulates protein-protein interactions during aging 期刊论文
SCIENCE, 2017, 355 (6331) : 1312-+
作者:  Li, Jun;  Bonkowski, Michael S.;  Moniot, Sebastien;  Zhang, Dapeng;  Hubbard, Basil P.;  Ling, Alvin J. Y.;  Rajman, Luis A.;  Qin, Bo;  Lou, Zhenkun;  Gorbunova, Vera;  Aravind, L.;  Steegborn, Clemens;  Sinclair, David A.
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
PARP inhibitors: Synthetic lethality in the clinic 期刊论文
SCIENCE, 2017, 355 (6330) : 1152-1158
作者:  Lord, Christopher J.;  Ashworth, Alan
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27
Response to Comment on "Ribose and related sugars from ultraviolet irradiation of interstellar ice analogs" 期刊论文
SCIENCE, 2017, 355 (6321) : 141B-U175
作者:  Meinert, Cornelia;  39;Hendecourt, Louis
收藏  |  浏览/下载:1/0  |  提交时间:2019/11/27
Comment on "Ribose and related sugars from ultraviolet irradiation of interstellar ice analogs" 期刊论文
SCIENCE, 2017, 355 (6321) : 141A-141A
作者:  Kawai, Jun
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27