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浏览/检索结果:
共77条,第1-10条
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Automatic precursor recognition and real-time forecasting of sudden explosive volcanic eruptions at Whakaari, New Zealand
期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:
Dempsey, D. E.
;
Cronin, S. J.
;
Mei, S.
;
Kempa-Liehr, A. W.
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/21
Improving the prediction of an atmospheric chemistry transport model using gradient-boosted regression trees
期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (13) : 8063-8082
作者:
Ivatt, Peter D.
;
Evans, Mathew J.
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/21
Characterizing soundscapes across diverse ecosystems using a universal acoustic feature set
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (29) : 17049-17055
作者:
Sethi, Sarab S.
;
Jones, Nick S.
;
Fulcher, Ben D.
;
Picinali, Lorenzo
;
Clink, Dena Jane
;
Klinck, Holger
;
Orme, C. David L.
;
Wrege, Peter H.
;
Ewers, Robert M.
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/09
machine learning
acoustic
soundscape
monitoring
ecology
Stable machine-learning parameterization of subgrid processes for climate modeling at a range of resolutions
期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:
Yuval, Janni
;
39;Gorman, Paul A.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/06
Spatio-temporal variation of reference evapotranspiration in northwest China based on CORDEX-EA
期刊论文
ATMOSPHERIC RESEARCH, 2020, 238
作者:
Yang, Linshan
;
Feng, Qi
;
Adamowski, Jan F.
;
Yin, Zhenliang
;
Wen, Xiaohu
;
Wu, Min
;
Jia, Bing
;
Hao, Qiang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/08/18
CORDEX-EA
Reference evapotranspiration
Machine learning algorithm
Northwest China
Linking large-scale circulation patterns to low-cloud properties
期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (12) : 7125-7138
作者:
Juliano, Timothy W.
;
Lebo, Zachary J.
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/06/22
Quantifying the drivers and predictability of seasonal changes in African fire
期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:
Yu, Yan
;
Mao, Jiafu
;
Thornton, Peter E.
;
Notaro, Michael
;
Wullschleger, Stan D.
;
Shi, Xiaoying
;
Hoffman, Forrest M.
;
Wang, Yaoping
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/06/16
Dynamic spatial-temporal precipitation distribution models for short-duration rainstorms in Shenzhen, China based on machine learning
期刊论文
ATMOSPHERIC RESEARCH, 2020, 237
作者:
Liu, Yuan-Yuan
;
Li, Lei
;
Liu, Ye-Sen
;
Chan, Pak Wai
;
Zhang, Wen-Hai
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/02
Short-duration rainstorm
Machine learning
Locally linear embedding method
Dynamic spatial-temporal distribution
Shenzhen
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease
期刊论文
NATURE, 2020, 577 (7790) : 399-+
作者:
Gate, David
;
Saligrama, Naresha
;
Leventhal, Olivia
;
Yang, Andrew C.
;
Unger, Michael S.
;
Middeldorp, Jinte
;
Chen, Kelly
;
Lehallier, Benoit
;
Channappa, Divya
;
De Los Santos, Mark B.
;
McBride, Alisha
;
Pluvinage, John
;
Elahi, Fanny
;
Tam, Grace Kyin-Ye
;
Kim, Yongha
;
Greicius, Michael
;
Wagner, Anthony D.
;
Aigner, Ludwig
;
Galasko, Douglas R.
;
Davis, Mark M.
;
Wyss-Coray, Tony
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/03
Alzheimer'
s disease is an incurable neurodegenerative disorder in which neuroinflammation has a critical function(1). However, little is known about the contribution of the adaptive immune response in Alzheimer'
s disease(2). Here, using integrated analyses of multiple cohorts, we identify peripheral and central adaptive immune changes in Alzheimer'
s disease. First, we performed mass cytometry of peripheral blood mononuclear cells and discovered an immune signature of Alzheimer'
s disease that consists of increased numbers of CD8(+) T effector memory CD45RA(+) (T-EMRA) cells. In a second cohort, we found that CD8(+) T-EMRA cells were negatively associated with cognition. Furthermore, single-cell RNA sequencing revealed that T cell receptor (TCR) signalling was enhanced in these cells. Notably, by using several strategies of single-cell TCR sequencing in a third cohort, we discovered clonally expanded CD8(+) T-EMRA cells in the cerebrospinal fluid of patients with Alzheimer'
s disease. Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with Alzheimer'
s disease to two separate Epstein-Barr virus antigens. These results reveal an adaptive immune response in the blood and cerebrospinal fluid in Alzheimer'
s disease and provide evidence of clonal, antigen-experienced T cells patrolling the intrathecal space of brains affected by age-related neurodegeneration.
Developing a novel hybrid model for the estimation of surface 8 h ozone (O-3) across the remote Tibetan Plateau during 2005-2018
期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (10) : 6159-6175
作者:
Li, Rui
;
Zhao, Yilong
;
Zhou, Wenhui
;
Meng, Ya
;
Zhang, Ziyu
;
Fu, Hongbo
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/06/01