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Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling 期刊论文
Science, 2021
作者:  Evan W. Weber;  Kevin R. Parker;  Elena Sotillo;  Rachel C. Lynn;  Hima Anbunathan;  John Lattin;  Zinaida Good;  Julia A. Belk;  Bence Daniel;  Dorota Klysz;  Meena Malipatlolla;  Peng Xu;  Malek Bashti;  Sabine Heitzeneder;  Louai Labanieh;  Panayiotis Vandris;  Robbie G. Majzner;  Yanyan Qi;  Katalin Sandor;  Ling-Chun Chen;  Snehit Prabhu;  Andrew J. Gentles;  Thomas J. Wandless;  Ansuman T. Satpathy;  Howard Y. Chang;  Crystal L. Mackall
收藏  |  浏览/下载：16/0  |  提交时间：2021/04/06
Monumental architecture at Aguada Fenix and the rise of Maya civilization 期刊论文
NATURE, 2020
作者:  Bedding, Timothy R.;  Murphy, Simon J.;  Hey, Daniel R.;  Huber, Daniel;  Li, Tanda;  Smalley, Barry;  Stello, Dennis;  White, Timothy R.;  Ball, Warrick H.;  Chaplin, William J.;  Colman, Isabel L.;  Fuller, Jim;  Gaidos, Eric;  Harbeck, Daniel R.;  Hermes, J. J.;  Holdsworth, Daniel L.;  Li, Gang;  Li, Yaguang;  Mann, Andrew W.;  Reese, Daniel R.;  Sekaran, Sanjay;  Yu, Jie;  Antoci, Victoria;  Bergmann, Christoph;  Brown, Timothy M.;  Howard, Andrew W.;  Ireland, Michael J.;  Isaacson, Howard;  Jenkins, Jon M.;  Kjeldsen, Hans;  McCully, Curtis;  Rabus, Markus;  Rains, Adam D.;  Ricker, George R.;  Tinney, Christopher G.;  Vanderspek, Roland K.
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/03

Archaeologists have traditionally thought that the development of Maya civilization was gradual, assuming that small villages began to emerge during the Middle Preclassic period (1000-350 bc  dates are calibrated throughout) along with the use of ceramics and the adoption of sedentism(1). Recent finds of early ceremonial complexes are beginning to challenge this model. Here we describe an airborne lidar survey and excavations of the previously unknown site of Aguada Fenix (Tabasco, Mexico) with an artificial plateau, which measures 1,400 m in length and 10 to 15 m in height and has 9 causeways radiating out from it. We dated this construction to between 1000 and 800 bc using a Bayesian analysis of radiocarbon dates. To our knowledge, this is the oldest monumental construction ever found in the Maya area and the largest in the entire pre-Hispanic history of the region. Although the site exhibits some similarities to the earlier Olmec centre of San Lorenzo, the community of Aguada Fenix probably did not have marked social inequality comparable to that of San Lorenzo. Aguada Fenix and other ceremonial complexes of the same period suggest the importance of communal work in the initial development of Maya civilization.


Lidar survey of the Maya lowlands uncovers the monumental site of Aguada Fenix, which dates to around 1000-800 bc and points to the role of communal construction in the development of Maya civilization.


  
Complexity revealed in the greening of the Arctic 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (2) : 106-117
作者:  Myers-Smith, Isla H.;  Kerby, Jeffrey T.;  Phoenix, Gareth K.;  Bjerke, Jarle W.;  Epstein, Howard E.;  Assmann, Jakob J.;  John, Christian;  Andreu-Hayles, Laia;  Angers-Blondin, Sandra;  Beck, Pieter S. A.;  Berner, Logan T.;  Bhatt, Uma S.;  Bjorkman, Anne D.;  Blok, Daan;  Bryn, Anders;  Christiansen, Casper T.;  Cornelissen, J. Hans C.;  Cunliffe, Andrew M.;  Elmendorf, Sarah C.;  Forbes, Bruce C.;  Goetz, Scott J.;  Hollister, Robert D.;  de Jong, Rogier;  Loranty, Michael M.;  Macias-Fauria, Marc;  Maseyk, Kadmiel;  Normand, Signe;  Olofsson, Johan;  Parker, Thomas C.;  Parmentier, Frans-Jan W.;  Post, Eric;  Schaepman-Strub, Gabriela;  Stordal, Frode;  Sullivan, Patrick F.;  Thomas, Haydn J. D.;  Tommervik, Hans;  Treharne, Rachael;  Tweedie, Craig E.;  Walker, Donald A.;  Wilmking, Martin;  Wipf, Sonja
收藏  |  浏览/下载：19/0  |  提交时间：2020/05/13
Great Expectations: Plans and Predictions for New Horizons Encounter With Kuiper Belt Object 2014 MU69 ("Ultima Thule") 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2018, 45 (16) : 8111-8120
作者:  Moore, Jeffrey M.;  McKinnon, William B.;  Cruikshank, Dale P.;  Gladstone, G. Randall;  Spencer, John R.;  Stern, S. Alan;  Weaver, Harold A.;  Singer, Kelsi N.;  Showalter, Mark R.;  Grundy, William M.;  Beyer, Ross A.;  White, Oliver L.;  Binzel, Richard P.;  Buie, Marc W.;  Buratti, Bonnie J.;  Cheng, Andrew F.;  Howett, Carly;  Olkin, Cathy B.;  Parker, Alex H.;  Porter, Simon B.;  Schenk, Paul M.;  Throop, Henry B.;  Verbiscer, Anne J.;  Young, Leslie A.;  Benecchi, Susan D.;  Bray, Veronica J.;  Chavez, Carrie L.;  Dhingra, Rajani D.;  Howard, Alan D.;  Lauer, Tod R.;  Lisse, C. M.;  Robbins, Stuart J.;  Runyon, Kirby D.;  Umurhan, Orkan M.
收藏  |  浏览/下载：10/0  |  提交时间：2019/04/09
An anatomic transcriptional atlas of human glioblastoma 期刊论文
SCIENCE, 2018, 360 (6389) : 660-663
作者:  Puchalski, Ralph B.;  Shah, Nameeta;  Miller, Jeremy;  Dalley, Rachel;  Nomura, Steve R.;  Yoon, Jae-Guen;  Smith, Kimberly A.;  Lankerovich, Michael;  Bertagnolli, Darren;  Bickley, Kris;  Boe, Andrew F.;  Brouner, Krissy;  Butler, Stephanie;  Caldejon, Shiella;  Chapin, Mike;  Datta, Suvro;  Dee, Nick;  Desta, Tsega;  Dolbeare, Tim;  Dotson, Nadezhda;  Ebbert, Amanda;  Feng, David;  Feng, Xu;  Fisher, Michael;  Gee, Garrett;  Goldy, Jeff;  Gourley, Lindsey;  Gregor, Benjamin W.;  Gu, Guangyu;  Hejazinia, Nika;  Hohmann, John;  Hothi, Parvinder;  Howard, Robert;  Joines, Kevin;  Kriedberg, Ali;  Kuan, Leonard;  Lau, Chris;  Lee, Felix;  Lee, Hwahyung;  Lemon, Tracy;  Long, Fuhui;  Mastan, Naveed;  Mott, Erika;  Murthy, Chantal;  Ngo, Kiet;  Olson, Eric;  Reding, Melissa;  Riley, Zack;  Rosen, David;  Sandman, David;  Shapovalova, Nadiya;  Slaughterbeck, Clifford R.;  Sodt, Andrew;  Stockdale, Graham;  Szafer, Aaron;  Wakeman, Wayne;  Wohnoutka, Paul E.;  White, Steven J.;  Marsh, Don;  Rostomily, Robert C.;  Ng, Lydia;  Dang, Chinh;  Jones, Allan;  Keogh, Bart;  Gittleman, Haley R.;  Barnholtz-Sloan, Jill S.;  Cimino, Patrick J.;  Uppin, Megha S.;  Keene, C. Dirk;  Farrokhi, Farrokh R.;  Lathia, Justin D.;  Berens, Michael E.;  Iavarone, Antonio;  Bernard, Amy;  Lein, Ed;  Phillips, John W.;  Rostad, Steven W.;  Cobbs, Charles;  Hawrylycz, Michael J.;  Foltz, Greg D.
收藏  |  浏览/下载：16/0  |  提交时间：2019/11/27
Integrated genomic and molecular characterization of cervical cancer 期刊论文
NATURE, 2017, 543 (7645) : 378-+
作者:  Burk, Robert D.;  Chen, Zigui;  Saller, Charles;  Tarvin, Katherine;  Carvalho, Andre L.;  Scapulatempo-Neto, Cristovam;  Silveira, Henrique C.;  Fregnani, Jose H.;  Creighton, Chad J.;  Anderson, Matthew L.;  Castro, Patricia;  Wang, Sophia S.;  Yau, Christina;  Benz, Christopher;  Robertson, A. Gordon;  Mungall, Karen;  Lim, Lynette;  Bowlby, Reanne;  Sadeghi, Sara;  Brooks, Denise;  Sipahimalani, Payal;  Mar, Richard;  Ally, Adrian;  Clarke, Amanda;  Mungall, Andrew J.;  Tam, Angela;  Lee, Darlene;  Chuah, Eric;  Schein, Jacqueline E.;  Tse, Kane;  Kasaian, Katayoon;  Ma, Yussanne;  Marra, Marco A.;  Mayo, Michael;  Balasundaram, Miruna;  Thiessen, Nina;  Dhalla, Noreen;  Carlsen, Rebecca;  Moore, Richard A.;  Holt, Robert A.;  Jones, Steven J. M.;  Wong, Tina;  Pantazi, Angeliki;  Parfenov, Michael;  Kucherlapati, Raju;  Hadjipanayis, Angela;  Seidman, Jonathan;  Kucherlapati, Melanie;  Ren, Xiaojia;  Xu, Andrew W.;  Yang, Lixing;  Park, Peter J.;  Lee, Semin;  Rabeno, Brenda;  Huelsenbeck-Dill, Lori;  Borowsky, Mark;  Cadungog, Mark;  Iacocca, Mary;  Petrelli, Nicholas;  Swanson, Patricia;  Ojesina, Akinyemi I.;  Le, Xuan;  Sandusky, George;  Adebamowo, Sally N.;  Akeredolu, Teniola;  Adebamowo, Clement;  Reynolds, Sheila M.;  Shmulevich, Ilya;  Shelton, Candace;  Crain, Daniel;  Mallery, David;  Curley, Erin;  Gardner, Johanna;  Penny, Robert;  Morris, Scott;  Shelton, Troy;  Liu, Jia;  Lolla, Laxmi;  Chudamani, Sudha;  Wu, Ye;  Birrer, Michael;  McLellan, Michael D.;  Bailey, Matthew H.;  Miller, Christopher A.;  Wyczalkowski, Matthew A.;  Fulton, Robert S.;  Fronick, Catrina C.;  Lu, Charles;  Mardis, Elaine R.;  Appelbaum, Elizabeth L.;  Schmidt, Heather K.;  Fulton, Lucinda A.;  Cordes, Matthew G.;  Li, Tiandao;  Ding, Li;  Wilson, Richard K.;  Rader, Janet S.;  Behmaram, Behnaz;  Uyar, Denise;  Bradley, William;  Wrangle, John;  Pastore, Alessandro;  Levine, Douglas A.;  Dao, Fanny;  Gao, Jianjiong;  Schultz, Nikolaus;  Sander, Chris;  Ladanyi, Marc;  Einstein, Mark;  Teeter, Randall;  Benz, Stephen;  Wentzensen, Nicolas;  Felau, Ina;  Zenklusen, Jean C.;  Bodelon, Clara;  Demchok, John A.;  Yang, Liming;  Sheth, Margi;  Ferguson, Martin L.;  Tarnuzzer, Roy;  Yang, Hannah;  Schiffman, Mark;  Zhang, Jiashan;  Wang, Zhining;  Davidsen, Tanja;  Olaniyan, Olayinka;  Hutter, Carolyn M.;  Sofia, Heidi J.;  Gordenin, Dmitry A.;  Chan, Kin;  Roberts, Steven A.;  Klimczak, Leszek J.;  Van Waes, Carter;  Chen, Zhong;  Saleh, Anthony D.;  Cheng, Hui;  Parfitt, Jeremy;  Bartlett, John;  Albert, Monique;  Arnaout, Angel;  Sekhon, Harman;  Gilbert, Sebastien;  Peto, Myron;  Myers, Jerome;  Harr, Jodi;  Eckman, John;  Bergsten, Julie;  Tucker, Kelinda;  Zach, Leigh Anne;  Karlan, Beth Y.;  Lester, Jenny;  Orsulic, Sandra;  Sun, Qiang;  Naresh, Rashi;  Pihl, Todd;  Wan, Yunhu;  Zaren, Howard;  Sapp, Jennifer;  Miller, Judy;  Drwiega, Paul;  Ojesina, Akinyemi I.;  Murray, Bradley A.;  Zhang, Hailei;  Cherniack, Andrew D.;  Sougnez, Carrie;  Pedamallu, Chandra Sekhar;  Lichtenstein, Lee;  Meyerson, Matthew;  Noble, Michael S.;  Heiman, David I.;  Voet, Doug;  Getz, Gad;  Saksena, Gordon;  Kim, Jaegil;  Shih, Juliann;  Cho, Juok;  Lawrence, Michael S.;  Gehlenborg, Nils;  Lin, Pei;  Beroukhim, Rameen;  Frazer, Scott;  Gabriel, Stacey B.;  Schumacher, Steven E.;  Leraas, Kristen M.;  Lichtenberg, Tara M.;  Zmuda, Erik;  Bowen, Jay;  Frick, Jessica;  Gastier-Foster, Julie M.;  Wise, Lisa;  Gerken, Mark;  Ramirez, Nilsa C.;  Danilova, Ludmila;  Cope, Leslie;  Baylin, Stephen B.;  Salvesen, Helga B.;  Vellano, Christopher P.;  Ju, Zhenlin;  Diao, Lixia;  Zhao, Hao;  Chong, Zechen;  Ryan, Michael C.;  Martinez-Ledesma, Emmanuel;  Verhaak, Roeland G.;  Byers, Lauren Averett;  Yuan, Yuan;  Chen, Ken;  Ling, Shiyun;  Mills, Gordon B.;  Lu, Yiling;  Akbani, Rehan;  Seth, Sahil;  Liang, Han;  Wang, Jing;  Han, Leng;  Weinstein, John N.;  Bristow, Christopher A.;  Zhang, Wei;  Mahadeshwar, Harshad S.;  Sun, Huandong;  Tang, Jiabin;  Zhang, Jianhua;  Song, Xingzhi;  Protopopov, Alexei;  Shaw, Kenna R. Mills;  Chin, Lynda;  Olabode, Oluwole;  Ojesina, Akinyemi I.;  DiSaia, Philip;  Radenbaugh, Amie;  Haussler, David;  Zhu, Jingchun;  Stuart, Josh;  Chalise, Prabhakar;  Koestler, Devin;  Fridley, Brooke L.;  Godwin, Andrew K.;  Madan, Rashna;  Ciriello, Giovanni;  Martinez, Cathleen;  Higgins, Kelly;  Bocklage, Therese;  Auman, J. Todd;  Perou, Charles M.;  Tan, Donghui;  Parker, Joel S.;  Hoadley, Katherine A.;  Wilkerson, Matthew D.;  Mieczkowski, Piotr A.;  Skelly, Tara;  Veluvolu, Umadevi;  Hayes, D. Neil;  Rathmell, W. Kimryn;  Hoyle, Alan P.;  Simons, Janae V.;  Wu, Junyuan;  Mose, Lisle E.;  Soloway, Matthew G.;  Balu, Saianand;  Meng, Shaowu;  Jefferys, Stuart R.;  Bodenheimer, Tom;  Shi, Yan;  Roach, Jeffrey;  Thorne, Leigh B.;  Boice, Lori;  Huang, Mei;  Jones, Corbin D.;  Zuna, Rosemary;  Walker, Joan;  Gunderson, Camille;  Snowbarger, Carie;  Brown, David;  Moxley, Katherine;  Moore, Kathleen;  Andrade, Kelsi;  Landrum, Lisa;  Mannel, Robert;  McMeekin, Scott;  Johnson, Starla;  Nelson, Tina;  Elishaev, Esther;  Dhir, Rajiv;  Edwards, Robert;  Bhargava, Rohit;  Tiezzi, Daniel G.;  Andrade, Jurandyr M.;  Noushmehr, Houtan;  Carlotti, Carlos Gilberto, Jr.;  Tirapelli, Daniela Pretti da Cunha;  Weisenberger, Daniel J.;  Van Den Berg, David J.;  Maglinte, Dennis T.;  Bootwalla, Moiz S.;  Lai, Phillip H.;  Triche, Timothy, Jr.;  Swisher, Elizabeth M.;  Agnew, Kathy J.;  Shelley, Carl Simon;  Laird, Peter W.;  Schwarz, Julie;  Grigsby, Perry;  Mutch, David
收藏  |  浏览/下载：13/0  |  提交时间：2019/04/09