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Data assimilation of a dense wind profiler network and its impact on convective forecasting 期刊论文
ATMOSPHERIC RESEARCH, 2020, 238
作者:  Wang, Cheng;  Chen, Yaodeng;  Chen, Min;  Shen, Jie
收藏  |  浏览/下载:11/0  |  提交时间:2020/08/18
Data assimilation  Wind profiler radar observation  Momentum control variables  Numerical weather prediction  
Human impacts on polycyclic aromatic hydrocarbon distribution in Chinese intertidal zones 期刊论文
NATURE SUSTAINABILITY, 2020
作者:  Lv, Min;  Luan, Xiaolin;  Liao, Chunyang;  Wang, Dongqi;  Liu, Dongyan;  Zhang, Gan;  Jiang, Guibin;  Chen, Lingxin
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/06
Direct links between hygroscopicity and mixing state of ambient aerosols: estimating particle hygroscopicity from their single-particle mass spectra 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (11) : 6273-6290
作者:  Wang, Xinning;  Ye, Xingnan;  Chen, Jian-Min;  Wang, Xiaofei;  Yang, Xin;  Fu, Tzung-May;  Zhu, Lei;  Liu, Chongxuan
收藏  |  浏览/下载:6/0  |  提交时间:2020/06/09
Characteristics and source apportionment of PM2.5-bound saccharides and carboxylic acids in Central Shanghai, China 期刊论文
ATMOSPHERIC RESEARCH, 2020, 237
作者:  Ren, Guofa;  Yan, Xiaoling;  Ma, Yingge;  Qiao, Liping;  Chen, Zhixiang;  Xin, Yilu;  Zhou, Min;  Shi, Yichao;  Zheng, Kewen;  Zhu, Shuhui;  Huang, Cheng;  Li, Li
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/02
PM2.5  Saccharides  Carboxylic acids  Seasonal variation  PCA  
Disruption of emergency response to vulnerable populations during floods 期刊论文
NATURE SUSTAINABILITY, 2020
作者:  Yu, Dapeng;  Yin, Jie;  Wilby, Robert L.;  Lane, Stuart N.;  Aerts, Jeroen C. J. H.;  Lin, Ning;  Liu, Min;  Yuan, Hongyong;  Chen, Jianguo;  Prudhomme, Christel;  Guan, Mingfu;  Baruch, Avinoam;  Johnson, Charlie W. D.;  Tule, Xi;  Yu, Lizhong;  Xu, Shiyuan
收藏  |  浏览/下载:19/0  |  提交时间:2020/05/20
Contrasting frontal and warm-sector heavy rainfalls over South China during the early-summer rainy season 期刊论文
ATMOSPHERIC RESEARCH, 2020, 235
作者:  Wu, Naigeng;  Ding, Xi;  Wen, Zhiping;  Chen, Guixing;  Meng, Zhiyong;  Lin, Liangxun;  Min, Jinzhong
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/02
Warm-sector heavy rainfall  Frontal heavy rainfall  Monsoon  Land-sea breeze  Diurnal variation  Early-summer rainy season  
The Great Oxidation Event expanded the genetic repertoire of arsenic metabolism and cycling 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (19) : 10414-10421
作者:  Chen, Song-Can;  Sun, Guo-Xin;  Yan, Yu;  Konstantinidis, Konstantinos T.;  Zhang, Si-Yu;  Deng, Ye;  Li, Xiao-Min;  Cui, Hui-Ling;  Musat, Florin;  Popp, Denny;  Rosen, Barry P.;  Zhu, Yong-Guan
收藏  |  浏览/下载:21/0  |  提交时间:2020/05/13
arsenic  detoxification  evolution  oxygen  biogeochemistry  
Upper Mantle Deformation of the Terror Rift and Northern Transantarctic Mountains in Antarctica: Insight From P Wave Anisotropic Tomography 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (9)
作者:  Zhang, Heng;  Zhao, Dapeng;  Ju, Changhui;  Li, Yunyue Elita;  Li, Guohui;  Ding, Min;  Chen, Shuze;  Zhao, Junmeng
收藏  |  浏览/下载:8/0  |  提交时间:2020/05/13
Estimation of Secondary Organic Aerosol Formation During a Photochemical Smog Episode in Shanghai, China 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2020, 125 (7)
作者:  Wang, Hongli;  Wang, Qian;  Gao, Yaqin;  Zhou, Min;  Jing, Shengao;  Qiao, Liping;  Yuan, Bin;  Huang, Dandan;  Huang, Cheng;  Lou, Shengrong;  Yan, Rusha;  de Gouw, Joost A.;  Zhang, Xuan;  Chen, Jianmin;  Chen, Changhong;  Tao, Shikang;  An, Jingyu;  Li, Yingjie
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/02
photochemistry  volatile organic compounds  secondary organic aerosols  Shanghai  
Injured adult neurons regress to an embryonic transcriptional growth state 期刊论文
NATURE, 2020, 581 (7806) : 77-+
作者:  Wang, Ruicong;  Li, Hongda;  Wu, Jianfeng;  Cai, Zhi-Yu;  Li, Baizhou;  Ni, Hengxiao;  Qiu, Xingfeng;  Chen, Hui;  Liu, Wei;  Yang, Zhang-Hua;  Liu, Min;  Hu, Jin;  Liang, Yaoji;  Lan, Ping;  Han, Jiahuai;  Mo, Wei
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/03

Grafts of spinal-cord-derived neural progenitor cells (NPCs) enable the robust regeneration of corticospinal axons and restore forelimb function after spinal cord injury(1)  however, the molecular mechanisms that underlie this regeneration are unknown. Here we perform translational profiling specifically of corticospinal tract (CST) motor neurons in mice, to identify their '  regenerative transcriptome'  after spinal cord injury and NPC grafting. Notably, both injury alone and injury combined with NPC grafts elicit virtually identical early transcriptomic responses in host CST neurons. However, in mice with injury alone this regenerative transcriptome is downregulated after two weeks, whereas in NPC-grafted mice this transcriptome is sustained. The regenerative transcriptome represents a reversion to an embryonic transcriptional state of the CST neuron. The huntingtin gene (Htt) is a central hub in the regeneration transcriptome  deletion of Htt significantly attenuates regeneration, which shows that Htt has a key role in neural plasticity after injury.


In mouse models of central nervous system injury, Htt is shown to be a key component of the regulatory program associated with reversion of the neuronal transcriptome to a less-mature state.