资源环境科技发展态势分析平台(GSTDTAP): 检索

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil 期刊论文
Science, 2021
作者: Nuno R. Faria; Thomas A. Mellan; Charles Whittaker; Ingra M. Claro; Darlan da S. Candido; Swapnil Mishra; Myuki A. E. Crispim; Flavia C. S. Sales; Iwona Hawryluk; John T. McCrone; Ruben J. G. Hulswit; Lucas A. M. Franco; Mariana S. Ramundo; Jaqueline G. de Jesus; Pamela S. Andrade; Thais M. Coletti; Giulia M. Ferreira; Camila A. M. Silva; Erika R. Manuli; Rafael H. M. Pereira; Pedro S. Peixoto; Moritz U. G. Kraemer; Nelson Gaburo; Cecilia da C. Camilo; Henrique Hoeltgebaum; William M. Souza; Esmenia C. Rocha; Leandro M. de Souza; Mariana C. de Pinho; Leonardo J. T. Araujo; Frederico S. V. Malta; Aline B. de Lima; Joice do P. Silva; Danielle A. G. Zauli; Alessandro C. de S. Ferreira; Ricardo P. Schnekenberg; Daniel J. Laydon; Patrick G. T. Walker; Hannah M. Schlüter; Ana L. P. dos Santos; Maria S. Vidal; Valentina S. Del Caro; Rosinaldo M. F. Filho; Helem M. dos Santos; Renato S. Aguiar; José L. Proença-Modena; Bruce Nelson; James A. Hay; Mélodie Monod; Xenia Miscouridou; Helen Coupland; Raphael Sonabend; Michaela Vollmer; Axel Gandy; Carlos A. Prete; Vitor H. Nascimento; Marc A. Suchard; Thomas A. Bowden; Sergei L. K. Pond; Chieh-Hsi Wu; Oliver Ratmann; Neil M. Ferguson; Christopher Dye; Nick J. Loman; Philippe Lemey; Andrew Rambaut; Nelson A. Fraiji; Maria do P. S. S. Carvalho; Oliver G. Pybus; Seth Flaxman; Samir Bhatt; Ester C. Sabino

收藏 | 浏览/下载：13/0 | 提交时间：2021/06/07

Realization of a multinode quantum network of remote solid-state qubits 期刊论文
Science, 2021
作者: M. Pompili; S. L. N. Hermans; S. Baier; H. K. C. Beukers; P. C. Humphreys; R. N. Schouten; R. F. L. Vermeulen; M. J. Tiggelman; L. dos Santos Martins; B. Dirkse; S. Wehner; R. Hanson

收藏 | 浏览/下载：14/0 | 提交时间：2021/04/20

Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors 期刊论文
Science, 2021
作者: Kasper Fugger; Ilirjana Bajrami; Mariana Silva Dos Santos; Sarah Jane Young; Simone Kunzelmann; Geoff Kelly; Graeme Hewitt; Harshil Patel; Robert Goldstone; Thomas Carell; Simon J. Boulton; James MacRae; Ian A. Taylor; Stephen C. West

收藏 | 浏览/下载：6/0 | 提交时间：2021/04/12

Stable Boundary Layer Regimes in Single-Column Models 期刊论文
Journal of the Atmospheric Sciences, 2020
作者: Felipe D. Costa; Otávio C. Acevedo; Luiz E. Medeiros; Rafael Maroneze; Franciano S. Puhales; Arlindo D. Carvalho Jr.; Luis F. Camponogara; Daniel M. dos Santos; Luca Mortarini

收藏 | 浏览/下载：6/0 | 提交时间：2020/05/25

Pharmacologic fibroblast reprogramming into photoreceptors restores vision 期刊论文
NATURE, 2020, 581 (7806) : 83-+
作者: Jiang, Mingkai; Medlyn, Belinda E.; Drake, John E.; Duursma, Remko A.; Anderson, Ian C.; Barton, Craig V. M.; Boer, Matthias M.; Carrillo, Yolima; Castaneda-Gomez, Laura; Collins, Luke; Crous, Kristine Y.; De Kauwe, Martin G.; dos Santos, Bruna M.; Emmerson, Kathryn M.; Facey, Sarah L.; Gherlenda, Andrew N.; Gimeno, Teresa E.; Hasegawa, Shun; Johnson, Scott N.; Kannaste, Astrid; Macdonald, Catriona A.; Mahmud, Kashif; Moore, Ben D.; Nazaries, Loic; Neilson, Elizabeth H. J.; Nielsen, Uffe N.; Niinemets, Ulo; Noh, Nam Jin; Ochoa-Hueso, Raul; Pathare, Varsha S.; Pendall, Elise; Pihlblad, Johanna; Pineiro, Juan; Powell, Jeff R.; Power, Sally A.; Reich, Peter B.; Renchon, Alexandre A.; Riegler, Markus; Rinnan, Riikka; Rymer, Paul D.; Salomon, Roberto L.; Singh, Brajesh K.; Smith, Benjamin; Tjoelker, Mark G.; Walker, Jennifer K. M.; Wujeska-Klause, Agnieszka; Yang, Jinyan; Zaehle, Soenke; Ellsworth, David S.

收藏 | 浏览/下载：46/0 | 提交时间：2020/07/03

Photoreceptor loss is the final common endpoint in most retinopathies that lead to irreversible blindness, and there are no effective treatments to restore vision(1,2). Chemical reprogramming of fibroblasts offers an opportunity to reverse vision loss however, the generation of sensory neuronal subtypes such as photoreceptors remains a challenge. Here we report that the administration of a set of five small molecules can chemically induce the transformation of fibroblasts into rod photoreceptor-like cells. The transplantation of these chemically induced photoreceptor-like cells (CiPCs) into the subretinal space of rod degeneration mice (homozygous for rd1, also known as Pde6b) leads to partial restoration of the pupil reflex and visual function. We show that mitonuclear communication is a key determining factor for the reprogramming of fibroblasts into CiPCs. Specifically, treatment with these five compounds leads to the translocation of AXIN2 to the mitochondria, which results in the production of reactive oxygen species, the activation of NF-kappa B and the upregulation of Ascl1. We anticipate that CiPCs could have therapeutic potential for restoring vision.

A set of five small molecules can induce the transformation of fibroblasts into rod photoreceptor-like cells, which can partially restore pupil reflex and visual function when transplanted into a rod degeneration mouse model.

Observation of two-neutrino double electron capture in Xe-124 with XENON1T 期刊论文
NATURE, 2019, 568 (7753) : 532-+
作者: Aprile, E.; Aalbers, J.; Agostini, F.; Alfonsi, M.; Althueser, L.; Amaro, F. D.; Anthony, M.; Antochi, V. C.; Arneodo, F.; Baudis, L.; Bauermeister, B.; Benabderrahmane, L.; Berger, T.; Breur, P. A.; Brown, A.; Brown, A.; Brown, E.; Bruenner, S.; Bruno, G.; Budnik, R.; Capelli, C.; Cardoso, J. M. R.; Cichon, D.; Coderre, D.; Colijn, A. P.; Conrad, J.; Cussonneau, J. P.; Decowski, M. P.; de Perio, P.; Di Gangi, P.; Di Giovanni, A.; Diglio, S.; Elykov, A.; Eurin, G.; Fei, J.; Ferella, A. D.; Fieguth, A.; Fulgione, W.; Rosso, A. Gallo; Galloway, M.; Gao, F.; Garbini, M.; Grandi, L.; Greene, Z.; Hasterok, C.; Hogenbirk, E.; Howlett, J.; Iacovacci, M.; Itay, R.; Joerg, F.; Kaminsky, B.; Kazama, S.; Kish, A.; Koltman, G.; Kopec, A.; Landsman, H.; Lang, R. F.; Levinson, L.; Lin, Q.; Lindemann, S.; Lindner, M.; Lombardi, F.; Lopes, J. A. M.; Fune, E. Lopez; Macolino, C.; Mahlstedt, J.; Manfredini, A.; Marignetti, F.; Undagoitia, T. Marrodan; Masbou, J.; Masson, D.; Mastroianni, S.; Messina, M.; Micheneau, K.; Miller, K.; Molinario, A.; Mora, K.; Murra, M.; Naganoma, J.; Ni, K.; Oberlack, U.; Odgers, K.; Pelssers, B.; Peres, R.; Piastra, F.; Pienaar, J.; Pizzella, V.; Plante, G.; Podviianiuk, R.; Priel, N.; Qiu, H.; Garcia, D. Ramirez; Reichard, S.; Riedel, B.; Rizzo, A.; Rocchetti, A.; Rupp, N.; dos Santos, J. M. F.; Sartorelli, G.; Sarcevic, N.; Scheibelhut, M.; Schindler, S.; Schreiner, J.; Schulte, D.; Schumann, M.; Lavina, L. Scotto; Selvi, M.; Shagin, P.; Shockley, E.; Silva, M.; Simgen, H.; Therreau, C.; Thers, D.; Toschi, F.; Trinchero, G.; Tunnell, C.; Upole, N.; Vargas, M.; Wack, O.; Wang, H.; Wang, Z.; Wei, Y.; Weinheimer, C.; Wenz, D.; Wittweg, C.; Wulf, J.; Ye, J.; Zhang, Y.; Zhu, T.; Zopounidis, J. P.

收藏 | 浏览/下载：14/0 | 提交时间：2019/11/27

Genomic and epidemiological monitoring of yellow fever virus transmission potential 期刊论文
SCIENCE, 2018, 361 (6405) : 894-+
作者: Faria, N. R.; Kraemer, M. U. G.; Hill, S. C.; de Jesus, J. Goes; Aguiar, R. S.; Iani, F. C. M.; Xavier, J.; Quick, J.; du Plessis, L.; Dellicour, S.; Theze, J.; Carvalho, R. D. O.; Baele, G.; Wu, C. -H.; Silveira, P. P.; Arruda, M. B.; Pereira, M. A.; Pereira, G. C.; Lourenco, J.; Obolski, U.; Abade, L.; Vasylyeva, T. I.; Giovanetti, M.; Yi, D.; Weiss, D. J.; Wint, G. R. W.; Shearer, F. M.; Funk, S.; Nikolay, B.; Fonseca, V.; Adelino, T. E. R.; Oliveira, M. A. A.; Silva, M. V. F.; Sacchetto, L.; Figueiredo, P. O.; Rezende, I. M.; Mello, E. M.; Said, R. F. C.; Santos, D. A.; Ferraz, M. L.; Brito, M. G.; Santana, L. F.; Menezes, M. T.; Brindeiro, R. M.; Tanuri, A.; dos Santos, F. C. P.; Cunha, M. S.; Nogueira, J. S.; Rocco, I. M.; da Costa, A. C.; Komninakis, S. C. V.; Azevedo, V.; Chieppe, A. O.; Araujo, E. S. M.; Mendonca, M. C. L.; dos Santos, C. C.; dos Santos, C. D.; Mares-Guia, A. M.; Nogueira, R. M. R.; Sequeira, P. C.; Abreu, R. G.; Garcia, M. H. O.; Abreu, A. L.; Okumoto, O.; Kroon, E. G.; de Albuquerque, C. F. C.; Lewandowski, K.; Pullan, S. T.; Carroll, M.; de Oliveira, T.; Sabino, E. C.; Souza, R. P.; Suchard, M. A.; Lemey, P.; Trindade, G. S.; Drumond, B. P.; Filippis, A. M. B.; Loman, N. J.; Cauchemez, S.; Alcantara, L. C. J.; Pybus, O. G.

收藏 | 浏览/下载：7/0 | 提交时间：2019/11/27

Quantifying long-term changes in carbon stocks and forest structure from Amazon forest degradation 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2018, 13 (6)
作者: Rappaport, Danielle I.; Morton, Douglas C.; Longo, Marcos; Keller, Michael; Dubayah, Ralph; dos-Santos, Maiza Nara

收藏 | 浏览/下载：10/0 | 提交时间：2019/04/09
aboveground biomass forest structure habitat understory fires carbon cycling airborne lidar REDD

Oogenesis and reproductive investment of Atlantic herring are functions of not only present but long-ago environmental influences as well 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (10) : 2634-2639
作者: Schmidt, Thassya C. dos Santos; Slotte, Aril; Kennedy, James; Sundby, Svein; Johannessen, Arne; Oskarsson, Gudmundur J.; Kurita, Yutaka; Stenseth, Nils C.; Kjesbu, Olav Sigurd

收藏 | 浏览/下载：8/0 | 提交时间：2019/11/27
fishery fecundity zooplankton lag effect recruitment

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