中文版 | English

在结果中检索

GSTDTAP

浏览/检索结果: 共19条，第1-10条 帮助

已选(0)清除 条数/页：   排序方式：
Targeting a neoantigen derived from a common TP53 mutation 期刊论文
Science, 2021
作者:  Emily Han-Chung Hsiue;  Katharine M. Wright;  Jacqueline Douglass;  Michael S. Hwang;  Brian J. Mog;  Alexander H. Pearlman;  Suman Paul;  Sarah R. DiNapoli;  Maximilian F. Konig;  Qing Wang;  Annika Schaefer;  Michelle S. Miller;  Andrew D. Skora;  P. Aitana Azurmendi;  Michael B. Murphy;  Qiang Liu;  Evangeline Watson;  Yana Li;  Drew M. Pardoll;  Chetan Bettegowda;  Nickolas Papadopoulos;  Kenneth W. Kinzler;  Bert Vogelstein;  Sandra B. Gabelli;  Shibin Zhou
收藏  |  浏览/下载：10/0  |  提交时间：2021/03/12
The age distribution of global soil carbon inferred from radiocarbon measurements 期刊论文
NATURE GEOSCIENCE, 2020
作者:  Shi, Zheng;  Allison, Steven D.;  He, Yujie;  Levine, Paul A.;  Hoyt, Alison M.;  Beem-Miller, Jeffrey;  Zhu, Qing;  Wieder, William R.;  Trumbore, Susan;  Randerson, James T.
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/06
Hydrothermal (NN)-N-15-N-15 abundances constrain the origins of mantle nitrogen 期刊论文
NATURE, 2020, 580 (7803) : 367-+
作者:  Zhao, Steven;  Jang, Cholsoon;  Liu, Joyce;  Uehara, Kahealani;  Gilbert, Michael;  Izzo, Luke;  Zeng, Xianfeng;  Trefely, Sophie;  Fernandez, Sully;  Carrer, Alessandro;  Miller, Katelyn D.;  Schug, Zachary T.;  Snyder, Nathaniel W.;  Gade, Terence P.;  Titchenell, Paul M.;  Rabinowitz, Joshua D.;  Wellen, Kathryn E.
收藏  |  浏览/下载：14/0  |  提交时间：2020/05/13

Nitrogen is the main constituent of the Earth'  s atmosphere, but its provenance in the Earth'  s mantle remains uncertain. The relative contribution of primordial nitrogen inherited during the Earth'  s accretion versus that subducted from the Earth'  s surface is unclear(1-6). Here we show that the mantle may have retained remnants of such primordial nitrogen. We use the rare (NN)-N-15-N-15 isotopologue of N-2 as a new tracer of air contamination in volcanic gas effusions. By constraining air contamination in gases from Iceland, Eifel (Germany) and Yellowstone (USA), we derive estimates of mantle delta N-15 (the fractional difference in N-15/N-14 from air), N-2/Ar-36 and N-2/He-3. Our results show that negative delta N-15 values observed in gases, previously regarded as indicating a mantle origin for nitrogen(7-10), in fact represent dominantly air-derived N-2 that experienced N-15/N-14 fractionation in hydrothermal systems. Using two-component mixing models to correct for this effect, the (NN)-N-15-N-15 data allow extrapolations that characterize mantle endmember delta N-15, N-2/Ar-36 and N-2/He-3 values. We show that the Eifel region has slightly increased delta N-15 and N-2/Ar-36 values relative to estimates for the convective mantle provided by mid-ocean-ridge basalts(11), consistent with subducted nitrogen being added to the mantle source. In contrast, we find that whereas the Yellowstone plume has delta N-15 values substantially greater than that of the convective mantle, resembling surface components(12-15), its N-2/Ar-36 and N-2/He-3 ratios are indistinguishable from those of the convective mantle. This observation raises the possibility that the plume hosts a primordial component. We provide a test of the subduction hypothesis with a two-box model, describing the evolution of mantle and surface nitrogen through geological time. We show that the effect of subduction on the deep nitrogen cycle may be less important than has been suggested by previous investigations. We propose instead that high mid-ocean-ridge basalt and plume delta N-15 values may both be dominantly primordial features.


  
Missing OH reactivity in the global marine boundary layer 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (6) : 4013-4029
作者:  Thames, Alexander B.;  Brune, William H.;  Miller, David O.;  Allen, Hannah M.;  Apel, Eric C.;  Blake, Donald R.;  Bui, T. Paul;  Commane, Roisin;  Crounse, John D.;  Daube, Bruce C.;  Diskin, Glenn S.;  DiGangi, Joshua P.;  Elkins, JamesW.;  Hall, Samuel R.;  Hanisco, Thomas F.;  Hannun, Reem A.;  Hintsa, Eric;  Hornbrook, Rebecca S.;  Kim, Michelle J.;  McKain, Kathryn;  Moore, Fred L.;  Nicely, Julie M.;  Peischl, Jeffrey;  Ryerson, Thomas B.;  St Clair, Jason M.;  Sweeney, Colm;  Teng, Alex;  Thompson, Chelsea R.;  Ullmann, Kirk;  Wennberg, Paul O.;  Wolfe, Glenn M.
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/02
Technologies and Policies to Decarbonize Global Industry: Review and Assessment of Mitigation Drivers through 2070 科技报告
来源：Resources for the Future. 出版年： 2020
作者:  Jeffrey Rissman;  Chris Bataille;  Eric Masanet;  Nate Aden;  William R. Morrow III;  Nan Zhou;  Neal Elliott;  Rebecca Dell;  Niko Heeren;  Brigitta Huckestein;  Joe Cresko;  Sabbie Miller;  Joyashree Roy;  Paul Fennel;  Betty Cremmins;  Thomas Koch Blank;  David Hone;  Ellen D. Williams;  Stephane de la Rue du Can;  Bill Sisson;  Mike Williams;  John Katzenberger;  Dallas Burtraw;  Girish Sethi;  He Ping;  David Danielson;  Hongyou Lu;  Tom Lorber;  Jens Dinkel;  and Jonas Helseth
收藏  |  浏览/下载：9/0  |  提交时间：2020/06/16
BIOMEDICINE Multivascular networks and functional intravascular topologies within biocompatible hydrogels 期刊论文
SCIENCE, 2019, 364 (6439) : 458-+
作者:  Grigoryan, Bagrat;  Paulsen, Samantha J.;  Corbett, Daniel C.;  Sazer, Daniel W.;  Fortin, Chelsea L.;  Zaita, Alexander J.;  Greenfield, Paul T.;  Calafat, Nicholas J.;  Gounley, John P.;  Ta, Anderson H.;  Johansson, Fredrik;  Randles, Amanda;  Rosenkrantz, Jessica E.;  Louis-Rosenberg, Jesse D.;  Galie, Peter A.;  Stevens, Kelly R.;  Miller, Jordan S.
收藏  |  浏览/下载：22/0  |  提交时间：2019/11/27
Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (38) : 9592-9597
作者:  Burnett, Richard;  Chen, Hong;  Szyszkowicz, Mieczyslaw;  Fann, Neal;  Hubbell, Bryan;  Pope, C. Arden;  Apte, Joshua S.;  Brauer, Michael;  Cohen, Aaron;  Weichenthal, Scott;  Coggins, Jay;  Di, Qian;  Brunekreef, Bert;  Frostad, Joseph;  Lim, Stephen S.;  Kan, Haidong;  Walker, Katherine D.;  Thurston, George D.;  Hayes, Richard B.;  Lim, Chris C.;  Turner, Michelle C.;  Jerrett, Michael;  Krewski, Daniel;  Gapstur, Susan M.;  Diver, W. Ryan;  Ostro, Bart;  Goldberg, Debbie;  Crouse, Daniel L.;  Martin, Randall V.;  Peters, Paul;  Pinault, Lauren;  Tjepkema, Michael;  van Donkelaar, Aaron;  Villeneuve, Paul J.;  Miller, Anthony B.;  Yin, Peng;  Zhou, Maigeng;  Wang, Lijun;  Janssen, Nicole A. H.;  Marra, Marten;  Atkinson, Richard W.;  Tsang, Hilda;  Thuan Quoc Thach;  Cannon, John B.;  Allen, Ryan T.;  Hart, Jaime E.;  Laden, Francine;  Cesaroni, Giulia;  Forastiere, Francesco;  Weinmayr, Gudrun;  Jaensch, Andrea;  Nagel, Gabriele;  Concin, Hans;  Spadaro, Joseph V.
收藏  |  浏览/下载：53/0  |  提交时间：2019/11/27
mortality  exposure  risk  concentration  fine particulate matter  
Response to Comment on "Tracking the global footprint of fisheries" 期刊论文
SCIENCE, 2018, 361 (6404)
作者:  Kroodsma, David A.;  Mayorga, Juan;  Hochberg, Timothy;  Miller, Nathan A.;  Boerder, Kristina;  Ferretti, Francesco;  Wilson, Alex;  Bergman, Bjorn;  White, Timothy D.;  Block, Barbara A.;  Woods, Paul;  Sullivan, Brian;  Costello, Christopher;  Worm, Boris
收藏  |  浏览/下载：6/0  |  提交时间：2019/11/27
An anatomic transcriptional atlas of human glioblastoma 期刊论文
SCIENCE, 2018, 360 (6389) : 660-663
作者:  Puchalski, Ralph B.;  Shah, Nameeta;  Miller, Jeremy;  Dalley, Rachel;  Nomura, Steve R.;  Yoon, Jae-Guen;  Smith, Kimberly A.;  Lankerovich, Michael;  Bertagnolli, Darren;  Bickley, Kris;  Boe, Andrew F.;  Brouner, Krissy;  Butler, Stephanie;  Caldejon, Shiella;  Chapin, Mike;  Datta, Suvro;  Dee, Nick;  Desta, Tsega;  Dolbeare, Tim;  Dotson, Nadezhda;  Ebbert, Amanda;  Feng, David;  Feng, Xu;  Fisher, Michael;  Gee, Garrett;  Goldy, Jeff;  Gourley, Lindsey;  Gregor, Benjamin W.;  Gu, Guangyu;  Hejazinia, Nika;  Hohmann, John;  Hothi, Parvinder;  Howard, Robert;  Joines, Kevin;  Kriedberg, Ali;  Kuan, Leonard;  Lau, Chris;  Lee, Felix;  Lee, Hwahyung;  Lemon, Tracy;  Long, Fuhui;  Mastan, Naveed;  Mott, Erika;  Murthy, Chantal;  Ngo, Kiet;  Olson, Eric;  Reding, Melissa;  Riley, Zack;  Rosen, David;  Sandman, David;  Shapovalova, Nadiya;  Slaughterbeck, Clifford R.;  Sodt, Andrew;  Stockdale, Graham;  Szafer, Aaron;  Wakeman, Wayne;  Wohnoutka, Paul E.;  White, Steven J.;  Marsh, Don;  Rostomily, Robert C.;  Ng, Lydia;  Dang, Chinh;  Jones, Allan;  Keogh, Bart;  Gittleman, Haley R.;  Barnholtz-Sloan, Jill S.;  Cimino, Patrick J.;  Uppin, Megha S.;  Keene, C. Dirk;  Farrokhi, Farrokh R.;  Lathia, Justin D.;  Berens, Michael E.;  Iavarone, Antonio;  Bernard, Amy;  Lein, Ed;  Phillips, John W.;  Rostad, Steven W.;  Cobbs, Charles;  Hawrylycz, Michael J.;  Foltz, Greg D.
收藏  |  浏览/下载：17/0  |  提交时间：2019/11/27
Tracking the global footprint of fisheries 期刊论文
SCIENCE, 2018, 359 (6378) : 904-907
作者:  Kroodsma, David A.;  Mayorga, Juan;  Hochberg, Timothy;  Miller, Nathan A.;  Boerder, Kristina;  Ferretti, Francesco;  Wilson, Alex;  Bergman, Bjorn;  White, Timothy D.;  Block, Barbara A.;  Woods, Paul;  Sullivan, Brian;  Costello, Christopher;  Worm, Boris
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/27