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Where does the dust deposited over the Sierra Nevada snow come from? 期刊论文
Atmospheric Chemistry and Physics, 2022
作者:  Huilin Huang, Yun Qian, Ye Liu, Cenlin He, Jianyu Zheng, Zhibo Zhang, and Antonis Gkikas
收藏  |  浏览/下载:19/0  |  提交时间:2022/07/08
Aqueous production of secondary organic aerosol from fossil-fuel emissions in winter Beijing haze 期刊论文
Proceedings of the National Academy of Science, 2021
作者:  Junfeng Wang;  Jianhuai Ye;  Qi Zhang;  Jian Zhao;  Yangzhou Wu;  Jingyi Li;  Dantong Liu;  Weijun Li;  Yange Zhang;  Cheng Wu;  Conghui Xie;  Yiming Qin;  Yali Lei;  Xiangpeng Huang;  Jianping Guo;  Pengfei Liu;  Pingqing Fu;  Yongjie Li;  Hyun Chul Lee;  Hyoungwoo Choi;  Jie Zhang;  Hong Liao;  Mindong Chen;  Yele Sun;  Xinlei Ge;  Scot T. Martin;  Daniel J. Jacob
收藏  |  浏览/下载:15/0  |  提交时间:2021/02/22
Localization and delocalization of light in photonic moire lattices 期刊论文
NATURE, 2020, 577 (7788) : 42-+
作者:  Wang, Peng;  Zheng, Yuanlin;  Chen, Xianfeng;  Huang, Changming;  Kartashov, Yaroslav V.;  Torner, Lluis;  Konotop, Vladimir V.;  Ye, Fangwei
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/03

Moire lattices consist of two superimposed identical periodic structures with a relative rotation angle. Moire lattices have several applications in everyday life, including artistic design, the textile industry, architecture, image processing, metrology and interferometry. For scientific studies, they have been produced using coupled graphene-hexagonal boron nitride monolayers(1,2), graphene-graphene layers(3,4) and graphene quasicrystals on a silicon carbide surface(5). The recent surge of interest in moire lattices arises from the possibility of exploring many salient physical phenomena in such systems  examples include commensurable-incommensurable transitions and topological defects(2), the emergence of insulating states owing to band flattening(3,6), unconventional superconductivity(4) controlled by the rotation angle(7,8), the quantum Hall effect(9), the realization of non-Abelian gauge potentials(10) and the appearance of quasicrystals at special rotation angles(11). A fundamental question that remains unexplored concerns the evolution of waves in the potentials defined by moire lattices. Here we experimentally create two-dimensional photonic moire lattices, which-unlike their material counterparts-have readily controllable parameters and symmetry, allowing us to explore transitions between structures with fundamentally different geometries (periodic, general aperiodic and quasicrystal). We observe localization of light in deterministic linear lattices that is based on flatband physics(6), in contrast to previous schemes based on light diffusion in optical quasicrystals(12), where disorder is required(13) for the onset of Anderson localization(14) (that is, wave localization in random media). Using commensurable and incommensurable moire patterns, we experimentally demonstrate the twodimensional localization-delocalization transition of light. Moire lattices may feature an almost arbitrary geometry that is consistent with the crystallographic symmetry groups of the sublattices, and therefore afford a powerful tool for controlling the properties of light patterns and exploring the physics of periodic-aperiodic phase transitions and two-dimensional wavepacket phenomena relevant to several areas of science, including optics, acoustics, condensed matter and atomic physics.


  
Notch signalling drives synovial fibroblast identity and arthritis pathology 期刊论文
NATURE, 2020, 582 (7811) : 259-+
作者:  Han, Xiaoping;  Zhou, Ziming;  Fei, Lijiang;  Sun, Huiyu;  Wang, Renying;  Chen, Yao;  Chen, Haide;  Wang, Jingjing;  Tang, Huanna;  Ge, Wenhao;  Zhou, Yincong;  Ye, Fang;  Jiang, Mengmeng;  Wu, Junqing;  Xiao, Yanyu;  Jia, Xiaoning;  Zhang, Tingyue;  Ma, Xiaojie;  Zhang, Qi;  Bai, Xueli;  Lai, Shujing;  Yu, Chengxuan;  Zhu, Lijun;  Lin, Rui;  Gao, Yuchi;  Wang, Min;  Wu, Yiqing;  Zhang, Jianming;  Zhan, Renya;  Zhu, Saiyong;  Hu, Hailan;  Wang, Changchun;  Chen, Ming;  Huang, He;  Liang, Tingbo;  Chen, Jianghua;  Wang, Weilin;  Zhang, Dan;  Guo, Guoji
收藏  |  浏览/下载:43/0  |  提交时间:2020/07/03

NOTCH3 signalling is shown to be the underlying driver of the differentiation and expansion of a subset of synovial fibroblasts implicated in the pathogenesis of rheumatoid arthritis.


The synovium is a mesenchymal tissue composed mainly of fibroblasts, with a lining and sublining that surround the joints. In rheumatoid arthritis the synovial tissue undergoes marked hyperplasia, becomes inflamed and invasive, and destroys the joint(1,2). It has recently been shown that a subset of fibroblasts in the sublining undergoes a major expansion in rheumatoid arthritis that is linked to disease activity(3-5)  however, the molecular mechanism by which these fibroblasts differentiate and expand is unknown. Here we identify a critical role for NOTCH3 signalling in the differentiation of perivascular and sublining fibroblasts that express CD90 (encoded by THY1). Using single-cell RNA sequencing and synovial tissue organoids, we found that NOTCH3 signalling drives both transcriptional and spatial gradients-emanating from vascular endothelial cells outwards-in fibroblasts. In active rheumatoid arthritis, NOTCH3 and Notch target genes are markedly upregulated in synovial fibroblasts. In mice, the genetic deletion of Notch3 or the blockade of NOTCH3 signalling attenuates inflammation and prevents joint damage in inflammatory arthritis. Our results indicate that synovial fibroblasts exhibit a positional identity that is regulated by endothelium-derived Notch signalling, and that this stromal crosstalk pathway underlies inflammation and pathology in inflammatory arthritis.


  
Reply to: Why fossil fuel producer subsidies matter 期刊论文
NATURE, 2020, 578 (7793) : E5-E7
作者:  Wang, Peng;  Zheng, Yuanlin;  Chen, Xianfeng;  Huang, Changming;  Kartashov, Yaroslav V.;  Torner, Lluis;  Konotop, Vladimir V.;  Ye, Fangwei
收藏  |  浏览/下载:24/0  |  提交时间:2020/05/13
Metabolic regulation of gene expression by histone lactylation 期刊论文
NATURE, 2019, 574 (7779) : 575-+
作者:  Zhang, Di;  Tang, Zhanyun;  Huang, He;  Zhou, Guolin;  Cui, Chang;  Weng, Yejing;  Liu, Wenchao;  Kim, Sunjoo;  Lee, Sangkyu;  Perez-Neut, Mathew;  Ding, Jun;  Czyz, Daniel;  Hu, Rong;  Ye, Zhen;  He, Maomao;  Zheng, Y. George;  Shuman, Howard A.;  Dai, Lunzhi;  Ren, Bing;  Roeder, Robert G.;  Becker, Lev;  Zhao, Yingming
收藏  |  浏览/下载:28/0  |  提交时间:2019/11/27
Super-elastic ferroelectric single-crystal membrane with continuous electric dipole rotation 期刊论文
SCIENCE, 2019, 366 (6464) : 475-+
作者:  Dong, Guohua;  Li, Suzhi;  Yao, Mouteng;  Zhou, Ziyao;  Zhang, Yong-Qiang;  Han, Xu;  Luo, Zhenlin;  Yao, Junxiang;  Peng, Bin;  Hu, Zhongqiang;  Huang, Houbing;  Jia, Tingting;  Li, Jiangyu;  Ren, Wei;  Ye, Zuo-Guang;  Ding, Xiangdong;  Sun, Jun;  Nan, Ce-Wen;  Chen, Long-Qing;  Li, Ju;  Liu, Ming
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Evolution of anthropogenic air pollutant emissions in Guangdong Province, China, from 2006 to 2015 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (18) : 11701-11719
作者:  Bian, Yahui;  Huang, Zhijiong;  Ou, Jiamin;  Zhong, Zhuangmin;  Xu, Yuanqian;  Zhang, Zhiwei;  Xiao, Xiao;  Ye, Xiao;  Wu, Yuqi;  Yin, Xiaohong;  Li, Cheng;  Chen, Liangfu;  Shao, Min;  Zheng, Junyu
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
China's response to a national land-system sustainability emergency 期刊论文
NATURE, 2018, 559 (7713) : 193-204
作者:  Bryan, Brett A.;  Gao, Lei;  Ye, Yanqiong;  Sun, Xiufeng;  Connor, Jeffery D.;  Crossman, Neville D.;  Stafford-Smith, Mark;  Wu, Jianguo;  He, Chunyang;  Yu, Deyong;  Liu, Zhifeng;  Li, Ang;  Huang, Qingxu;  Ren, Hai;  Deng, Xiangzheng;  Zheng, Hua;  Niu, Jianming;  Han, Guodong;  Hou, Xiangyang
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly 期刊论文
SCIENCE, 2017, 358 (6365) : 933-+
作者:  Yuan, Ling;  Huang, Xing-Yao;  Liu, Zhong-Yu;  Zhang, Feng;  Zhu, Xing-Liang;  Yu, Jiu-Yang;  Ji, Xue;  Xu, Yan-Peng;  Li, Guanghui;  Li, Cui;  Wang, Hong-Jiang;  Deng, Yong-Qiang;  Wu, Menghua;  Cheng, Meng-Li;  Ye, Qing;  Xie, Dong-Yang;  Li, Xiao-Feng;  Wang, Xiangxi;  Shi, Weifeng;  Hu, Baoyang;  Shi, Pei-Yong;  Xu, Zhiheng;  Qin, Cheng-Feng
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27