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Direct field evidence of autocatalytic iodine release from atmospheric aerosol 期刊论文
Proceedings of the National Academy of Science, 2021
作者:  Yee Jun Tham;  Xu-Cheng He;  Qinyi Li;  Carlos A. Cuevas;  Jiali Shen;  Joni Kalliokoski;  Chao Yan;  Siddharth Iyer;  Tuuli Lehmusjärvi;  Sehyun Jang;  Roseline C. Thakur;  Lisa Beck;  Deniz Kemppainen;  Miska Olin;  Nina Sarnela;  Jyri Mikkilä;  Jani Hakala;  Marjan Marbouti;  Lei Yao;  Haiyan Li;  Wei Huang;  Yonghong Wang;  Daniela Wimmer;  Qiaozhi Zha;  Juhani Virkanen;  T. Gerard Spain;  Simon O'Doherty;  Tuija Jokinen;  Federico Bianchi;  Tuukka Petäjä;  Douglas R. Worsnop;  Roy L. Mauldin;  Jurgita Ovadnevaite;  Darius Ceburnis;  Norbert M. Maier;  Markku Kulmala;  Colin O’Dowd;  Miikka Dal Maso;  Alfonso Saiz-Lopez;  Mikko Sipilä
收藏  |  浏览/下载：21/0  |  提交时间：2021/01/28
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
Global picophytoplankton niche partitioning predicts overall positive response to ocean warming 期刊论文
NATURE GEOSCIENCE, 2020, 13 (2) : 116-+
作者:  Flombaum, Pedro;  Wang, Wei-Lei;  Primeau, Francois W.;  Martiny, Adam C.
收藏  |  浏览/下载：6/0  |  提交时间：2020/05/13
Reversible epitaxial electrodeposition of metals in battery anodes 期刊论文
SCIENCE, 2019, 366 (6465) : 645-+
作者:  Zheng, Jingxu;  Zhao, Qing;  Tang, Tian;  Yin, Jiefu;  Quilty, Calvin D.;  Renderos, Genesis D.;  Liu, Xiaotun;  Deng, Yue;  Wang, Lei;  Bock, David C.;  Jaye, Cherno;  Zhang, Duhan;  Takeuchi, Esther S.;  Takeuchi, Kenneth J.;  Marschilok, Amy C.;  Archer, Lynden A.
收藏  |  浏览/下载：18/0  |  提交时间：2020/02/17
Historical and genomic data reveal the influencing factors on global transmission velocity of plague during the Third Pandemic 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (24) : 11833-11838
作者:  Xu, Lei;  Stige, Leif C.;  Leirs, Herwig;  Neerinckx, Simon;  Gage, Kenneth L.;  Yang, Ruifu;  Liu, Qiyong;  Bramanti, Barbara;  Dean, Katharine R.;  Tang, Hui;  Sun, Zhe;  Stenseth, Nils Chr.;  Zhang, Zhibin
收藏  |  浏览/下载：15/0  |  提交时间：2019/11/27
Yersinia pestis  Third Pandemic  climate change  global transmission velocity  historical and genomic data  
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair 期刊论文
SCIENCE, 2018, 362 (6417) : 909-+
作者:  Shook, Brett A.;  Wasko, Renee R.;  Rivera-Gonzalez, Guillermo C.;  Salazar-Gatzimas, Emilio;  Lopez-Giraldez, Francesc;  Dash, Biraja C.;  Munoz-Rojas, Andres R.;  Aultman, Krystal D.;  Zwick, Rachel K.;  Lei, Vivian;  Arbiser, Jack L.;  Miller-Jensen, Kathryn;  Clark, Damon A.;  Hsia, Henry C.;  Horsley, Valerie
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
Rapid transition from continental breakup to igneous oceanic crust in the South China Sea 期刊论文
NATURE GEOSCIENCE, 2018, 11 (10) : 782-+
作者:  Larsen, H. C.;  Mohn, G.;  Nirrengarten, M.;  Sun, Z.;  Stock, J.;  Jian, Z.;  Klaus, A.;  Alvarez-Zarikian, C. A.;  Boaga, J.;  Bowden, S. A.;  Briais, A.;  Chen, Y.;  Cukur, D.;  Dadd, K.;  Ding, W.;  Dorais, M.;  Ferre, E. C.;  Ferreira, F.;  Furusawa, A.;  Gewecke, A.;  Hinojosa, J.;  Hofig, T. W.;  Hsiung, K. H.;  Huang, B.;  Huang, E.;  Huang, X. L.;  Jiang, S.;  Jin, H.;  Johnson, B. G.;  Kurzawski, R. M.;  Lei, C.;  Li, B.;  Li, L.;  Li, Y.;  Lin, J.;  Liu, C.;  Liu, Z.;  Luna, A. J.;  Lupi, C.;  McCarthy, A.;  Ningthoujam, L.;  Osono, N.;  Peate, D. W.;  Persaud, P.;  Qiu, N.;  Robinson, C.;  Satolli, S.;  Sauermilch, I;  Schindlbeck, J. C.;  Skinner, S.;  Straub, S.;  Su, X.;  Su, C.;  Tian, L.;  Van Der Zwan, F. M.;  Wan, S.;  Wu, H.;  Xiang, R.;  Yadav, R.;  Yi, L.;  Yu, P. S.;  Zhang, C.;  Zhang, J.;  Zhang, Y.;  Zhao, N.;  Zhong, G.;  Zhong, L.
收藏  |  浏览/下载：13/0  |  提交时间：2019/04/09
Global evaluation and calibration of a passive air sampler for gaseous mercury 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2018, 18 (8) : 5905-5919
作者:  McLagan, David S.;  Mitchell, Carl P. J.;  Steffen, Alexandra;  Hung, Hayley;  Shin, Cecilia;  Stupple, Geoff W.;  Olson, Mark L.;  Luke, Winston T.;  Kelley, Paul;  Howard, Dean;  Edwards, Grant C.;  Nelson, Peter F.;  Xiao, Hang;  Sheu, Guey-Rong;  Dreyer, Annekatrin;  Huang, Haiyong;  Hussain, Batual Abdul;  Lei, Ying D.;  Tavshunsky, Ilana;  Wania, Frank
收藏  |  浏览/下载：9/0  |  提交时间：2019/04/09
Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design 期刊论文
SCIENCE, 2018, 359 (6373) : 290-+
作者:  Du, Yushen;  Xin, Li;  Shi, Yuan;  Zhang, Tian-Hao;  Wu, Nicholas C.;  Dai, Lei;  Gong, Danyang;  Brar, Gurpreet;  Shu, Sara;  Luo, Jiadi;  Reiley, William;  Tseng, Yen-Wen;  Bai, Hongyan;  Wu, Ting-Ting;  Wang, Jieru;  Shu, Yuelong;  Sun, Ren
收藏  |  浏览/下载：8/0  |  提交时间：2019/11/27
Chiral Majorana fermion modes in a quantum anomalous Hall insulator-superconductor structure 期刊论文
SCIENCE, 2017, 357 (6348) : 294-299
作者:  He, Qing Lin;  Pan, Lei;  Stern, Alexander L.;  Burks, Edward C.;  Che, Xiaoyu;  Yin, Gen;  Wang, Jing;  Lian, Biao;  Zhou, Quan;  Choi, Eun Sang;  Murata, Koichi;  Kou, Xufeng;  Chen, Zhijie;  Nie, Tianxiao;  Shao, Qiming;  Fan, Yabin;  Zhang, Shou-Cheng;  Liu, Kai;  Xia, Jing;  Wang, Kang L.
收藏  |  浏览/下载：15/0  |  提交时间：2019/11/27