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Potential precipitation predictability decreases under future warming 期刊论文
Geophysical Research Letters, 2020
作者:  Lei Xu;  Chong Zhang;  Nengcheng Chen;  Hamid Moradkhani;  Pao‐;  Shin Chu;  Xiang Zhang
收藏  |  浏览/下载:7/0  |  提交时间:2020/11/09
SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation 期刊论文
Science, 2020
作者:  Xin Wu;  Yun Wang;  Rui Huang;  Qujing Gai;  Haofei Liu;  Meimei Shi;  Xiang Zhang;  Yonglin Zuo;  Longjuan Chen;  Qiwen Zhao;  Yu Shi;  Fengchao Wang;  Xiaowei Yan;  Huiping Lu;  Senlin Xu;  Xiaohong Yao;  Lin Chen;  Xia Zhang;  Qiang Tian;  Ziyan Yang;  Bo Zhong;  Chen Dong;  Yan Wang;  Xiu-Wu Bian;  Xindong Liu
收藏  |  浏览/下载:19/0  |  提交时间:2020/08/25
Subseasonal Prediction of Land Cold Extremes in Boreal Wintertime 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2020, 125 (13)
作者:  Xiang, Baoqiang;  Sun, Y. Qiang;  Chen, Jan-Huey;  Johnson, Nathaniel C.;  Jiang, Xianan
收藏  |  浏览/下载:12/0  |  提交时间:2020/08/18
subseasonal prediction  extremes  surface air temperature  predictability sources  land-atmosphere coupling  
Characterization of Aerosol Type Over East Asia by 4.4 km MISR Product: First Insight and General Performance 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2020, 125 (13)
作者:  Tao, Minghui;  Wang, Jun;  Li, Rong;  Chen, Liangfu;  Xu, Xiaoguang;  Wang, Lunche;  Tao, Jinhua;  Wang, Zifeng;  Xiang, Juan
收藏  |  浏览/下载:10/0  |  提交时间:2020/08/18
aerosol type  MISR  East Asia  characterization  performance  
Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat 期刊论文
Science, 2020
作者:  Hongwei Wang;  Silong Sun;  Wenyang Ge;  Lanfei Zhao;  Bingqian Hou;  Kai Wang;  Zhongfan Lyu;  Liyang Chen;  Shoushen Xu;  Jun Guo;  Min Li;  Peisen Su;  Xuefeng Li;  Guiping Wang;  Cunyao Bo;  Xiaojian Fang;  Wenwen Zhuang;  Xinxin Cheng;  Jianwen Wu;  Luhao Dong;  Wuying Chen;  Wen Li;  Guilian Xiao;  Jinxiao Zhao;  Yongchao Hao;  Ying Xu;  Yu Gao;  Wenjing Liu;  Yanhe Liu;  Huayan Yin;  Jiazhu Li;  Xiang Li;  Yan Zhao;  Xiaoqian Wang;  Fei Ni;  Xin Ma;  Anfei Li;  Steven S. Xu;  Guihua Bai;  Eviatar Nevo;  Caixia Gao;  Herbert Ohm;  Lingrang Kong
收藏  |  浏览/下载:16/0  |  提交时间:2020/05/25
Spatial-temporal variations and process analysis of O-3 pollution in Hangzhou during the G20 summit 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (10) : 5963-5976
作者:  Ni, Zhi-Zhen;  Luo, Kun;  Gao, Yang;  Gao, Xiang;  Jiang, Fei;  Huang, Cheng;  Fan, Jian-Ren;  Fu, Joshua S.;  Chen, Chang-Hong
收藏  |  浏览/下载:7/0  |  提交时间:2020/05/20
Intermolecular vibrational energy transfer enabled by microcavity strong light–matter coupling 期刊论文
Science, 2020
作者:  Bo Xiang;  Raphael F. Ribeiro;  Matthew Du;  Liying Chen;  Zimo Yang;  Jiaxi Wang;  Joel Yuen-Zhou;  Wei Xiong
收藏  |  浏览/下载:9/0  |  提交时间:2020/05/13
Molecular Characterization of Organosulfates in Highly Polluted Atmosphere Using Ultra-High-Resolution Mass Spectrometry 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2020, 125 (8)
作者:  Cai, Dongmei;  Wang, Xinke;  Chen, Jianmin;  Li, Xiang
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/02
Organosulfates  Molecular Characterization  ultra-high-resolution mass spectrometry  Formation mechanism  
Origin of complexity in haemoglobin evolution 期刊论文
NATURE, 2020
作者:  Cheema, Suraj S.;  Kwon, Daewoong;  Shanker, Nirmaan;  dos Reis, Roberto;  Hsu, Shang-Lin;  Xiao, Jun;  Zhang, Haigang;  Wagner, Ryan;  Datar, Adhiraj;  McCarter, Margaret R.;  Serrao, Claudy R.;  Yadav, Ajay K.;  Karbasian, Golnaz;  Hsu, Cheng-Hsiang;  Tan, Ava J.;  Wang, Li-Chen;  Thakare, Vishal;  Zhang, Xiang;  Mehta, Apurva;  Karapetrova, Evguenia;  Chopdekar, Rajesh, V;  Shafer, Padraic;  Arenholz, Elke;  Hu, Chenming;  Proksch, Roger;  Ramesh, Ramamoorthy;  Ciston, Jim;  Salahuddin, Sayeef
收藏  |  浏览/下载:50/0  |  提交时间:2020/07/03

Most proteins associate into multimeric complexes with specific architectures(1,2), which often have functional properties such as cooperative ligand binding or allosteric regulation(3). No detailed knowledge is available about how any multimer and its functions arose during evolution. Here we use ancestral protein reconstruction and biophysical assays to elucidate the origins of vertebrate haemoglobin, a heterotetramer of paralogous alpha- and beta-subunits that mediates respiratory oxygen transport and exchange by cooperatively binding oxygen with moderate affinity. We show that modern haemoglobin evolved from an ancient monomer and characterize the historical '  missing link'  through which the modern tetramer evolved-a noncooperative homodimer with high oxygen affinity that existed before the gene duplication that generated distinct alpha- and beta-subunits. Reintroducing just two post-duplication historical substitutions into the ancestral protein is sufficient to cause strong tetramerization by creating favourable contacts with more ancient residues on the opposing subunit. These surface substitutions markedly reduce oxygen affinity and even confer cooperativity, because an ancient linkage between the oxygen binding site and the multimerization interface was already an intrinsic feature of the protein'  s structure. Our findings establish that evolution can produce new complex molecular structures and functions via simple genetic mechanisms that recruit existing biophysical features into higher-level architectures.


Experimental analysis of reconstructed ancestral globins reveals that haemoglobin'  s complex tetrameric structure and oxygen-binding functions evolved by simple genetic and biophysical mechanisms.


  
CO2 mineralization and utilization by alkaline solid wastes for potential carbon reduction 期刊论文
NATURE SUSTAINABILITY, 2020, 3 (5) : 399-405
作者:  Pan, Shu-Yuan;  Chen, Yi-Hung;  Fan, Liang-Shih;  Kim, Hyunook;  Gao, Xiang;  Ling, Tung-Chai;  Chiang, Pen-Chi;  Pei, Si-Lu;  Gu, Guowei
收藏  |  浏览/下载:11/0  |  提交时间:2020/05/13