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Insight Into Major Active Faults in Central Myanmar and the Related Geodynamic Sources 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (8)
作者:  Mon, Chit Thet;  Gong, Xuan;  Wen, Yun;  Jiang, Mingming;  Chen, Qi-Fu;  Zhang, Miao;  Hou, Guangbing;  Thant, Myo;  Sein, Kyaing;  He, Yumei
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/02
earthquake relocation  Myanmar crustal seismicity  Kabaw Fault Zone  Sagaing Fault  Central Basin  
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
The robustness of the skewness as an early warning signal for abrupt climate change 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2019, 39 (15) : 5672-5687
作者:  Xie, Xiao-Qiang;  He, Wen-Ping;  Gu, Bin;  Mei, Ying;  Wang, Jinsong
收藏  |  浏览/下载:18/0  |  提交时间:2020/02/17
abrupt climate change  early warning signal  skewness coefficient  stochastic differential equation  
Transpiration of Moso bamboo in southern China is influenced by ramet age, phenology, and drought 期刊论文
FOREST ECOLOGY AND MANAGEMENT, 2019, 450
作者:  Gu, Daxing;  He, Wen;  Huang, Kechao;  Otieno, Dennis;  Zhou, Cuiming;  He, Chengxin;  Huang, Yuqing
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Phyllostachys edulis  Sap flow  Transpiration  Soil drought  Phenological effect  
Stabilization of atmospheric nitrogen deposition in China over the past decade 期刊论文
NATURE GEOSCIENCE, 2019, 12 (6) : 424-+
作者:  Yu, Guirui;  Jia, Yanlong;  He, Nianpeng;  Zhu, Jianxing;  Chen, Zhi;  Wang, Qiufeng;  Piao, Shilong;  Liu, Xuejun;  He, Honglin;  Guo, Xuebing;  Wen, Zhang;  Li, Pan;  Ding, Guoan;  Goulding, Keith
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/26
Can kurtosis be an early warning signal for abrupt climate change? 期刊论文
CLIMATE DYNAMICS, 2019, 52 (11) : 6863-6876
作者:  Xie, Xiao-qiang;  He, Wen-ping;  Gu, Bin;  Mei, Ying;  Zhao, Shan-shan
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/26
Early warning signal  Abrupt climate change  Kurtosis coefficient  Critical point  
Simulating evaluation and projection of the climate zones over China by CMIP5 models 期刊论文
CLIMATE DYNAMICS, 2019, 52: 2597-2612
作者:  He, Wen-ping;  Zhao, Shan-shan;  Wu, Qiong;  Jiang, Yun-di;  Wan, Shiquan
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/26
Climate zone  CMIP5  Evaluation of climate model  Projection  DT10  
Spatiotemporal Variability in Land Surface Temperature Over the Mountainous Region Affected by the 2008 Wenchuan Earthquake From 2000 to 2017 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019, 124 (4) : 1975-1991
作者:  Zhao, Wei;  He, Juelin;  Yin, Gaofei;  Wen, Fengping;  Wu, Hua
收藏  |  浏览/下载:5/0  |  提交时间:2019/04/09
annual temperature cycle  land surface temperature  MODIS  trend analysis  Wenchuan earthquake  global change  
How can prescribed burning and harvesting restore shortleaf pine-oak woodland at the landscape scale in central United States? Modeling joint effects of harvest and fire regimes 期刊论文
FOREST ECOLOGY AND MANAGEMENT, 2018, 410: 201-210
作者:  Jin, Wenchi;  He, Hong S.;  Shifley, Stephen R.;  Wang, Wen J.;  Kabrick, John M.;  Davidson, Brian K.
收藏  |  浏览/下载:10/0  |  提交时间:2019/04/09
Pinus echinata  Quercus  Woodland  Ecological restoration  Modeling  Landscape scale  LANDIS PRO  
Decadal Shift in West China Autumn Precipitation and its Association With Sea Surface Temperature 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2018, 123 (2) : 835-847
作者:  Wei, Ting;  He, Shengping;  Yan, Qing;  Dong, Wenjie;  Wen, Xiaohang
收藏  |  浏览/下载:6/0  |  提交时间:2019/04/09
West China autumn precipitation  decadal shift  sea surface temperature  numerical simulation