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Dietary modifications for enhanced cancer therapy 期刊论文
NATURE, 2020, 579 (7800) : 507-517
作者:  Keller, Matthew D.;  Ching, Krystal L.;  Liang, Feng-Xia;  Dhabaria, Avantika;  Tam, Kayan;  Ueberheide, Beatrix M.;  Unutmaz, Derya;  Torres, Victor J.;  Cadwell, Ken
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/03

Tumours depend on nutrients supplied by the host for their growth and survival. Modifications to the host'  s diet can change nutrient availability in the tumour microenvironment, which might represent a promising strategy for inhibiting tumour growth. Dietary modifications can limit tumour-specific nutritional requirements, alter certain nutrients that target the metabolic vulnerabilities of the tumour, or enhance the cytotoxicity of anti-cancer drugs. Recent reports have suggested that modification of several nutrients in the diet can alter the efficacy of cancer therapies, and some of the newest developments in this quickly expanding field are reviewed here. The results discussed indicate that the dietary habits and nutritional state of a patient must be taken into account during cancer research and therapy.


  
Climate change and overfishing increase neurotoxicant in marine predators 期刊论文
NATURE, 2019, 572 (7771) : 648-+
作者:  Schartup, Amina T.;  Thackray, Colin P.;  Qureshi, Asif;  Dassuncao, Clifton;  Gillespie, Kyle;  Hanke, Alex;  Sunderland, Elsie M.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Rapid Pliocene adaptive radiation of modern kangaroos 期刊论文
SCIENCE, 2018, 362 (6410) : 72-74
作者:  Couzens, Aidan M. C.;  Prideaux, Gavin J.
收藏  |  浏览/下载:1/0  |  提交时间:2019/11/27
Ancient goat genomes reveal mosaic domestication in the Fertile Crescent 期刊论文
SCIENCE, 2018, 361 (6397) : 85-87
作者:  Daly, Kevin G.;  Delser, Pierpaolo Maisano;  Mullin, Victoria E.;  Scheu, Amelie;  Mattiangeli, Valeria;  Teasdale, Matthew D.;  Hare, Andrew J.;  Burger, Joachim;  Verdugo, Marta Pereira;  Collins, Matthew J.;  Kehati, Ron;  Erek, Cevdet Merih;  Bar-Oz, Guy;  Pompanon, Francois;  Cumer, Tristan;  Cakirlar, Canan;  Mohaseb, Azadeh Fatemeh;  Decruyenaere, Delphine;  Davoudi, Hossein;  Cevik, Ozlem;  Rollefson, Gary;  Vigne, Jean-Denis;  Khazaeli, Roya;  Fathi, Homa;  Doost, Sanaz Beizaee;  Sorkhani, Roghayeh Rahimi;  Vahdati, Ali Akbar;  Sauer, Eberhard W.;  Kharanaghi, Hossein Azizi;  Maziar, Sepideh;  Gasparian, Boris;  Pinhasi, Ron;  Martin, Louise;  Orton, David;  Arbuckle, Benjamin S.;  Benecke, Norbert;  Manica, Andrea;  Horwitz, Liora Kolska;  Mashkour, Marjan;  Bradley, Daniel G.
收藏  |  浏览/下载:16/0  |  提交时间:2019/11/27
Reducing food's environmental impacts through producers and consumers 期刊论文
SCIENCE, 2018, 360 (6392) : 987-+
作者:  Poore, J.;  Nemecek, T.
收藏  |  浏览/下载:1/0  |  提交时间:2019/11/27
Evaluating the environmental impacts of dietary recommendations 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (51) : 13412-13417
作者:  Behrens, Paul;  Kiefte-de Jong, Jessica C.;  Bosker, Thijs;  Rodrigues, Joao F. D.;  de Koning, Arjan;  Tukker, Arnold
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/27
sustainable diets  MRIO  environmental impacts  dietary change  
Selenium deficiency risk predicted to increase under future climate change 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (11) : 2848-2853
作者:  Jones, Gerrad D.;  Droz, Boris;  Greve, Peter;  Gottschalk, Pia;  Poffet, Deyan;  McGrath, Steve P.;  Seneviratne, Sonia I.;  Smith, Pete;  Winkel, Lenny H. E.
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
selenium  soils  global distribution  prediction  climate change