Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1038/s41586-020-2124-0 |
Dietary modifications for enhanced cancer therapy | |
Keller, Matthew D.1,2; Ching, Krystal L.1,2; Liang, Feng-Xia3,4; Dhabaria, Avantika3,5; Tam, Kayan1; Ueberheide, Beatrix M.3,5,6; Unutmaz, Derya7; Torres, Victor J.1; Cadwell, Ken1,2,8 | |
2020-03-01 | |
发表期刊 | NATURE |
ISSN | 0028-0836 |
EISSN | 1476-4687 |
出版年 | 2020 |
卷号 | 579期号:7800页码:507-517 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文关键词 | Tumours depend on nutrients supplied by the host for their growth and survival. Modifications to the host' s diet can change nutrient availability in the tumour microenvironment, which might represent a promising strategy for inhibiting tumour growth. Dietary modifications can limit tumour-specific nutritional requirements, alter certain nutrients that target the metabolic vulnerabilities of the tumour, or enhance the cytotoxicity of anti-cancer drugs. Recent reports have suggested that modification of several nutrients in the diet can alter the efficacy of cancer therapies, and some of the newest developments in this quickly expanding field are reviewed here. The results discussed indicate that the dietary habits and nutritional state of a patient must be taken into account during cancer research and therapy. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000521825500018 |
WOS关键词 | ONE-CARBON METABOLISM ; FATTY-ACID OXIDATION ; GLUTAMINE-METABOLISM ; METHIONINE RESTRICTION ; SERINE BIOSYNTHESIS ; CALORIE RESTRICTION ; CELL-PROLIFERATION ; TRANSFORMED-CELLS ; KETOGENIC DIET ; HIGH-FRUCTOSE |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/281084 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.NYU, Sch Med, Dept Microbiol, New York, NY 10016 USA; 2.NYU, Sch Med, Skirball Inst, Kimmel Ctr Biol & Med, New York, NY 10016 USA; 3.New York Univ Langone Hlth, Div Adv Res Technol, New York, NY USA; 4.New York Univ Langone Hlth, Microscopy Labratory, New York, NY USA; 5.New York Univ Langone Hlth, Prote Lab, New York, NY USA; 6.Laura & Isaac Perlmutter Canc Ctr, New York, NY USA; 7.Jackson Lab Genom Med, Farmington, CT USA; 8.New York Univ Langone Hlth, Dept Med, Div Gastroenterol & Hepatol, New York, NY 10016 USA |
推荐引用方式 GB/T 7714 | Keller, Matthew D.,Ching, Krystal L.,Liang, Feng-Xia,et al. Dietary modifications for enhanced cancer therapy[J]. NATURE,2020,579(7800):507-517. |
APA | Keller, Matthew D..,Ching, Krystal L..,Liang, Feng-Xia.,Dhabaria, Avantika.,Tam, Kayan.,...&Cadwell, Ken.(2020).Dietary modifications for enhanced cancer therapy.NATURE,579(7800),507-517. |
MLA | Keller, Matthew D.,et al."Dietary modifications for enhanced cancer therapy".NATURE 579.7800(2020):507-517. |
条目包含的文件 | 条目无相关文件。 |
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