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Double averaging analysis applied to a large eddy simulation of coupled turbulent overlying and porewater flow 期刊论文
Water Resources Research, 2021
作者:  Yan Ping Lian;  Jonathan Dallmann;  Benjamin Sonin;  Kevin R. Roche;  Aaron I. Packman;  Wing Kam Liu;  Gregory J. Wagner
收藏  |  浏览/下载：8/0  |  提交时间：2021/10/22
Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants 期刊论文
Science, 2021
作者:  Lingshu Wang;  Tongqing Zhou;  Yi Zhang;  Eun Sung Yang;  Chaim A. Schramm;  Wei Shi;  Amarendra Pegu;  Olamide K. Oloniniyi;  Amy R. Henry;  Samuel Darko;  Sandeep R. Narpala;  Christian Hatcher;  David R. Martinez;  Yaroslav Tsybovsky;  Emily Phung;  Olubukola M. Abiona;  Avan Antia;  Evan M. Cale;  Lauren A. Chang;  Misook Choe;  Kizzmekia S. Corbett;  Rachel L. Davis;  Anthony T. DiPiazza;  Ingelise J. Gordon;  Sabrina Helmold Hait;  Tandile Hermanus;  Prudence Kgagudi;  Farida Laboune;  Kwanyee Leung;  Tracy Liu;  Rosemarie D. Mason;  Alexandra F. Nazzari;  Laura Novik;  Sarah O’Connell;  Sijy O’Dell;  Adam S. Olia;  Stephen D. Schmidt;  Tyler Stephens;  Christopher D. Stringham;  Chloe Adrienna Talana;  I-Ting Teng;  Danielle A. Wagner;  Alicia T. Widge;  Baoshan Zhang;  Mario Roederer;  Julie E. Ledgerwood;  Tracy J. Ruckwardt;  Martin R. Gaudinski;  Penny L. Moore;  Nicole A. Doria-Rose;  Ralph S. Baric;  Barney S. Graham;  Adrian B. McDermott;  Daniel C. Douek;  Peter D. Kwong;  John R. Mascola;  Nancy J. Sullivan;  John Misasi
收藏  |  浏览/下载：21/0  |  提交时间：2021/08/17
The recent emergence of Arctic Amplification 期刊论文
Geophysical Research Letters, 2021
作者:  M. R. England;  I. Eisenman;  N. J. Lutsko;  T. J. W. Wagner
收藏  |  浏览/下载：5/0  |  提交时间：2021/07/27
Reciprocal repulsions instruct the precise assembly of parallel hippocampal networks 期刊论文
Science, 2021
作者:  Daniel T. Pederick;  Jan H. Lui;  Ellen C. Gingrich;  Chuanyun Xu;  Mark J. Wagner;  Yuanyuan Liu;  Zhigang He;  Stephen R. Quake;  Liqun Luo
收藏  |  浏览/下载：19/0  |  提交时间：2021/06/15
Revealing x-ray and gamma ray temporal and spectral similarities in the GRB 190829A afterglow 期刊论文
Science, 2021
作者:  H.E.S.S. Collaboration;  H. Abdalla;  F. Aharonian;  F. Ait Benkhali;  E. O. Angüner;  C. Arcaro;  C. Armand;  T. Armstrong;  H. Ashkar;  M. Backes;  V. Baghmanyan;  V. Barbosa Martins;  A. Barnacka;  M. Barnard;  Y. Becherini;  D. Berge;  K. Bernlöhr;  B. Bi;  E. Bissaldi;  M. Böttcher;  C. Boisson;  J. Bolmont;  M. de Bony de Lavergne;  M. Breuhaus;  F. Brun;  P. Brun;  M. Bryan;  M. Büchele;  T. Bulik;  T. Bylund;  S. Caroff;  A. Carosi;  S. Casanova;  T. Chand;  S. Chandra;  A. Chen;  G. Cotter;  M. Curyło;  J. Damascene Mbarubucyeye;  I. D. Davids;  J. Davies;  C. Deil;  J. Devin;  L. Dirson;  A. Djannati-Ataï;  A. Dmytriiev;  A. Donath;  V. Doroshenko;  L. Dreyer;  C. Duffy;  J. Dyks;  K. Egberts;  F. Eichhorn;  S. Einecke;  G. Emery;  J.-P. Ernenwein;  K. Feijen;  S. Fegan;  A. Fiasson;  G. Fichet de Clairfontaine;  G. Fontaine;  S. Funk;  M. Füßling;  S. Gabici;  Y. A. Gallant;  G. Giavitto;  L. Giunti;  D. Glawion;  J. F. Glicenstein;  M.-H. Grondin;  J. Hahn;  M. Haupt;  G. Hermann;  J. A. Hinton;  W. Hofmann;  C. Hoischen;  T. L. Holch;  M. Holler;  M. Hörbe;  D. Horns;  D. Huber;  M. Jamrozy;  D. Jankowsky;  F. Jankowsky;  A. Jardin-Blicq;  V. Joshi;  I. Jung-Richardt;  E. Kasai;  M. A. Kastendieck;  K. Katarzyński;  U. Katz;  D. Khangulyan;  B. Khélifi;  S. Klepser;  W. Kluźniak;  Nu. Komin;  R. Konno;  K. Kosack;  D. Kostunin;  M. Kreter;  G. Lamanna;  A. Lemière;  M. Lemoine-Goumard;  J.-P. Lenain;  F. Leuschner;  C. Levy;  T. Lohse;  I. Lypova;  J. Mackey;  J. Majumdar;  D. Malyshev;  D. Malyshev;  V. Marandon;  P. Marchegiani;  A. Marcowith;  A. Mares;  G. Martí-Devesa;  R. Marx;  G. Maurin;  P. J. Meintjes;  M. Meyer;  A. Mitchell;  R. Moderski;  L. Mohrmann;  A. Montanari;  C. Moore;  P. Morris;  E. Moulin;  J. Muller;  T. Murach;  K. Nakashima;  A. Nayerhoda;  M. de Naurois;  H. Ndiyavala;  J. Niemiec;  L. Oakes;  P. O’Brien;  H. Odaka;  S. Ohm;  L. Olivera-Nieto;  E. de Ona Wilhelmi;  M. Ostrowski;  S. Panny;  M. Panter;  R. D. Parsons;  G. Peron;  B. Peyaud;  Q. Piel;  S. Pita;  V. Poireau;  A. Priyana Noel;  D. A. Prokhorov;  H. Prokoph;  G. Pühlhofer;  M. Punch;  A. Quirrenbach;  S. Raab;  R. Rauth;  P. Reichherzer;  A. Reimer;  O. Reimer;  Q. Remy;  M. Renaud;  F. Rieger;  L. Rinchiuso;  C. Romoli;  G. Rowell;  B. Rudak;  E. Ruiz-Velasco;  V. Sahakian;  S. Sailer;  H. Salzmann;  D. A. Sanchez;  A. Santangelo;  M. Sasaki;  M. Scalici;  J. Schäfer;  F. Schüssler;  H. M. Schutte;  U. Schwanke;  M. Seglar-Arroyo;  M. Senniappan;  A. S. Seyffert;  N. Shafi;  J. N. S. Shapopi;  K. Shiningayamwe;  R. Simoni;  A. Sinha;  H. Sol;  A. Specovius;  S. Spencer;  M. Spir-Jacob;  Ł. Stawarz;  L. Sun;  R. Steenkamp;  C. Stegmann;  S. Steinmassl;  C. Steppa;  T. Takahashi;  T. Tam;  T. Tavernier;  A. M. Taylor;  R. Terrier;  J. H. E. Thiersen;  D. Tiziani;  M. Tluczykont;  L. Tomankova;  M. Tsirou;  R. Tuffs;  Y. Uchiyama;  D. J. van der Walt;  C. van Eldik;  C. van Rensburg;  B. van Soelen;  G. Vasileiadis;  J. Veh;  C. Venter;  P. Vincent;  J. Vink;  H. J. Völk;  Z. Wadiasingh;  S. J. Wagner;  J. Watson;  F. Werner;  R. White;  A. Wierzcholska;  Yu Wun Wong;  A. Yusafzai;  M. Zacharias;  R. Zanin;  D. Zargaryan;  A. A. Zdziarski;  A. Zech;  S. J. Zhu;  J. Zorn;  S. Zouari;  N. Żywucka;  P. Evans;  K. Page
收藏  |  浏览/下载：29/0  |  提交时间：2021/06/15
Role of iodine oxoacids in atmospheric aerosol nucleation 期刊论文
Science, 2021
作者:  Xu-Cheng He;  Yee Jun Tham;  Lubna Dada;  Mingyi Wang;  Henning Finkenzeller;  Dominik Stolzenburg;  Siddharth Iyer;  Mario Simon;  Andreas Kürten;  Jiali Shen;  Birte Rörup;  Matti Rissanen;  Siegfried Schobesberger;  Rima Baalbaki;  Dongyu S. Wang;  Theodore K. Koenig;  Tuija Jokinen;  Nina Sarnela;  Lisa J. Beck;  João Almeida;  Stavros Amanatidis;  António Amorim;  Farnoush Ataei;  Andrea Baccarini;  Barbara Bertozzi;  Federico Bianchi;  Sophia Brilke;  Lucía Caudillo;  Dexian Chen;  Randall Chiu;  Biwu Chu;  António Dias;  Aijun Ding;  Josef Dommen;  Jonathan Duplissy;  Imad El Haddad;  Loïc Gonzalez Carracedo;  Manuel Granzin;  Armin Hansel;  Martin Heinritzi;  Victoria Hofbauer;  Heikki Junninen;  Juha Kangasluoma;  Deniz Kemppainen;  Changhyuk Kim;  Weimeng Kong;  Jordan E. Krechmer;  Aleksander Kvashin;  Totti Laitinen;  Houssni Lamkaddam;  Chuan Ping Lee;  Katrianne Lehtipalo;  Markus Leiminger;  Zijun Li;  Vladimir Makhmutov;  Hanna E. Manninen;  Guillaume Marie;  Ruby Marten;  Serge Mathot;  Roy L. Mauldin;  Bernhard Mentler;  Ottmar Möhler;  Tatjana Müller;  Wei Nie;  Antti Onnela;  Tuukka Petäjä;  Joschka Pfeifer;  Maxim Philippov;  Ananth Ranjithkumar;  Alfonso Saiz-Lopez;  Imre Salma;  Wiebke Scholz;  Simone Schuchmann;  Benjamin Schulze;  Gerhard Steiner;  Yuri Stozhkov;  Christian Tauber;  António Tomé;  Roseline C. Thakur;  Olli Väisänen;  Miguel Vazquez-Pufleau;  Andrea C. Wagner;  Yonghong Wang;  Stefan K. Weber;  Paul M. Winkler;  Yusheng Wu;  Mao Xiao;  Chao Yan;  Qing Ye;  Arttu Ylisirniö;  Marcel Zauner-Wieczorek;  Qiaozhi Zha;  Putian Zhou;  Richard C. Flagan;  Joachim Curtius;  Urs Baltensperger;  Markku Kulmala;  Veli-Matti Kerminen;  Theo Kurtén;  Neil M. Donahue;  Rainer Volkamer;  Jasper Kirkby;  Douglas R. Worsnop;  Mikko Sipilä
收藏  |  浏览/下载：11/0  |  提交时间：2021/02/17
The Influence of Meltwater on Phytoplankton Blooms Near the Sea‐Ice Edge 期刊论文
Geophysical Research Letters, 2020
作者:  C. W. Lester;  T. J. W. Wagner;  Dylan E. McNamara;  M. R. Cape
收藏  |  浏览/下载：5/0  |  提交时间：2020/12/22
Repetitive Ozone Exposures and Evaluation of Pulmonary Inflammation and Remodeling in Diabetic Mouse Strains 期刊论文
Environmental Health Perspectives, 2020
作者:  James G. Wagner;  Christina E. Barkauskas;  Aaron Vose;  Ryan P. Lewandowski;  Jack R. Harkema;  Robert M. Tighe
收藏  |  浏览/下载：7/0  |  提交时间：2020/12/07
Photon-recoil imaging: Expanding the view of nonlinear x-ray physics 期刊论文
Science, 2020
作者:  U. Eichmann;  H. Rottke;  S. Meise;  J.-E. Rubensson;  J. Söderström;  M. Agåker;  C. Såthe;  M. Meyer;  T. M. Baumann;  R. Boll;  A. De Fanis;  P. Grychtol;  M. Ilchen;  T. Mazza;  J. Montano;  V. Music;  Y. Ovcharenko;  D. E. Rivas;  S. Serkez;  R. Wagner;  S. Eisebitt
收藏  |  浏览/下载：7/0  |  提交时间：2020/09/30
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease 期刊论文
NATURE, 2020, 577 (7790) : 399-+
作者:  Gate, David;  Saligrama, Naresha;  Leventhal, Olivia;  Yang, Andrew C.;  Unger, Michael S.;  Middeldorp, Jinte;  Chen, Kelly;  Lehallier, Benoit;  Channappa, Divya;  De Los Santos, Mark B.;  McBride, Alisha;  Pluvinage, John;  Elahi, Fanny;  Tam, Grace Kyin-Ye;  Kim, Yongha;  Greicius, Michael;  Wagner, Anthony D.;  Aigner, Ludwig;  Galasko, Douglas R.;  Davis, Mark M.;  Wyss-Coray, Tony
收藏  |  浏览/下载：6/0  |  提交时间：2020/07/03

Alzheimer'  s disease is an incurable neurodegenerative disorder in which neuroinflammation has a critical function(1). However, little is known about the contribution of the adaptive immune response in Alzheimer'  s disease(2). Here, using integrated analyses of multiple cohorts, we identify peripheral and central adaptive immune changes in Alzheimer'  s disease. First, we performed mass cytometry of peripheral blood mononuclear cells and discovered an immune signature of Alzheimer'  s disease that consists of increased numbers of CD8(+) T effector memory CD45RA(+) (T-EMRA) cells. In a second cohort, we found that CD8(+) T-EMRA cells were negatively associated with cognition. Furthermore, single-cell RNA sequencing revealed that T cell receptor (TCR) signalling was enhanced in these cells. Notably, by using several strategies of single-cell TCR sequencing in a third cohort, we discovered clonally expanded CD8(+) T-EMRA cells in the cerebrospinal fluid of patients with Alzheimer'  s disease. Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with Alzheimer'  s disease to two separate Epstein-Barr virus antigens. These results reveal an adaptive immune response in the blood and cerebrospinal fluid in Alzheimer'  s disease and provide evidence of clonal, antigen-experienced T cells patrolling the intrathecal space of brains affected by age-related neurodegeneration.