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Satellite and Ocean Data Reveal Marked Increase in Earth's Heating Rate 期刊论文
Geophysical Research Letters, 2021
作者:  Norman G. Loeb;  Gregory C. Johnson;  Tyler J. Thorsen;  John M. Lyman;  Fred G. Rose;  Seiji Kato
收藏  |  浏览/下载：13/0  |  提交时间：2021/06/24
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
Examining Biases in Diurnally Integrated Shortwave Irradiances due to Two- and Four-Stream Approximations in a Cloudy Atmosphere 期刊论文
JOURNAL OF THE ATMOSPHERIC SCIENCES, 2020, 77 (2) : 551-581
作者:  Ham, Seung-Hee;  Kato, Seiji;  Rose, Fred G.
收藏  |  浏览/下载：6/0  |  提交时间：2020/07/02
Cloud radiative effects  Radiation budgets  Radiative fluxes  Radiative transfer  Shortwave radiation  Remote sensing  
Decomposing Shortwave Top-of-Atmosphere and Surface Radiative Flux Variations in Terms of Surface and Atmospheric Contributions 期刊论文
JOURNAL OF CLIMATE, 2019, 32 (16) : 5003-5019
作者:  Loeb, Norman G.;  Wang, Hailan;  Rose, Fred G.;  Kato, Seiji;  Smith, William L., Jr.;  Sun-Mack, Sunny
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/27
Satellite observations  Model evaluation  performance  Climate variability  Interannual variability  
Radiative Heating Rates Computed With Clouds Derived From Satellite-Based Passive and Active Sensors and their Effects on Generation of Available Potential Energy 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019, 124 (3) : 1720-1740
作者:  Kato, Seiji;  Rose, Fred G.;  Ham, Seung Hee;  Rutan, David A.;  Radkevich, Alexander;  Caldwell, Thomas E.;  Sun-Mack, Sunny;  Miller, Walter F.;  Chen, Yan
收藏  |  浏览/下载：7/0  |  提交时间：2019/04/09
heating rate  radiation  clouds  available potential energy  
Observation-Based Decomposition of Radiative Perturbations and Radiative Kernels 期刊论文
JOURNAL OF CLIMATE, 2018, 31 (24) : 10039-10058
作者:  Thorsen, Tyler J.;  Kato, Seiji;  Loeb, Norman G.;  Rose, Fred G.
收藏  |  浏览/下载：9/0  |  提交时间：2019/04/09
Radiation budgets  Radiative fluxes  Remote sensing  Anomalies  
Determining the Shortwave Radiative Flux From Earth Polychromatic Imaging Camera 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2018, 123 (20) : 11479-11491
作者:  Su, Wenying;  Liang, Lusheng;  Doelling, David R.;  Minnis, Patrick;  Duda, David P.;  Khlopenkov, Konstantin;  Thieman, Mandana M.;  Loeb, Norman G.;  Kato, Seiji;  Valero, Francisco P. J.;  Wang, Hailan;  Rose, Fred G.
收藏  |  浏览/下载：9/0  |  提交时间：2019/04/09
Surface Irradiances of Edition 4.0 Clouds and the Earth's Radiant Energy System (CERES) Energy Balanced and Filled (EBAF) Data Product 期刊论文
JOURNAL OF CLIMATE, 2018, 31 (11) : 4501-4527
作者:  Kato, Seiji;  Rose, Fred G.;  Rutan, David A.;  Thorsen, Tyler J.;  Loeb, Norman G.;  Doelling, David R.;  Huang, Xianglei;  Smith, William L.;  Su, Wenying;  Ham, Seung-Hee
收藏  |  浏览/下载：13/0  |  提交时间：2019/04/09
Impact of Ice Cloud Microphysics on Satellite Cloud Retrievals and Broadband Flux Radiative Transfer Model Calculations 期刊论文
JOURNAL OF CLIMATE, 2018, 31 (5) : 1851-1864
作者:  Loeb, Norman G.;  Yang, Ping;  Rose, Fred G.;  Hong, Gang;  Sun-Mack, Sunny;  Minnis, Patrick;  Kato, Seiji;  Ham, Seung-Hee;  Smith, William L., Jr.;  Hioki, Souichiro;  Tang, Guanglin
收藏  |  浏览/下载：6/0  |  提交时间：2019/04/09
Clouds and the Earth's Radiant Energy System (CERES) Energy Balanced and Filled (EBAF) Top-of-Atmosphere (TOA) Edition-4.0 Data Product 期刊论文
JOURNAL OF CLIMATE, 2018, 31 (2) : 895-918
作者:  Loeb, Norman G.;  Doelling, David R.;  Wang, Hailan;  Su, Wenying;  Nguyen, Cathy;  Corbett, Joseph G.;  Liang, Lusheng;  Mitrescu, Cristian;  Rose, Fred G.;  Kato, Seiji
收藏  |  浏览/下载：10/0  |  提交时间：2019/04/09