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Direct copolymerization of ethylene with protic comonomers enabled by multinuclear Ni catalysts 期刊论文
Nature Communications, 2021
作者:  Ji, Gang;  Chen, Zhou;  Wang, Xiao-Yan;  Ning, Xiao-Shan;  Xu, Chong-Jie;  Zhang, Xing-Min;  Tao, Wen-Jie;  Li, Jun-Fang;  Gao, Yanshan;  Shen, Qi;  Sun, Xiu-Li;  Wang, Hao-Yang;  Zhao, Jun-Bo;  Zhang, Bo;  Guo, Yin-Long;  Zhao, Yanan;  Sun, Jiajie;  Luo, Yi;  Tang, Yong
收藏  |  浏览/下载:18/0  |  提交时间:2021/11/15
Stabilizing black-phase formamidinium perovskite formation at room temperature and high humidity 期刊论文
Science, 2021
作者:  Wei Hui;  Lingfeng Chao;  Hui Lu;  Fei Xia;  Qi Wei;  Zhenhuang Su;  Tingting Niu;  Lei Tao;  Bin Du;  Deli Li;  Yue Wang;  He Dong;  Shouwei Zuo;  Bixin Li;  Wei Shi;  Xueqin Ran;  Ping Li;  Hui Zhang;  Zhongbin Wu;  Chenxin Ran;  Lin Song;  Guichuan Xing;  Xingyu Gao;  Jing Zhang;  Yingdong Xia;  Yonghua Chen;  Wei Huang
收藏  |  浏览/下载:21/0  |  提交时间:2021/04/06
Boiled or Bottled: Regional and Seasonal Exposures to Drinking Water Contamination and Household Air Pollution in Rural China 期刊论文
Environmental Health Perspectives, 2020
作者:  Alasdair Cohen;  Ajay Pillarisetti;  Qing Luo;  Qi Zhang;  Hongxing Li;  Gemei Zhong;  Gang Zhu;  John M. ColfordJr.;  Kirk R. Smith;  Isha Ray;  Yong Tao
收藏  |  浏览/下载:7/0  |  提交时间:2020/12/07
Depth‐dependent soil organic carbon dynamics of croplands across the Chengdu Plain of China from the 1980s to the 2010s 期刊论文
Global Change Biology, 2020
作者:  Qiquan Li;  Aiwen Li;  Tianfei Dai;  Zemeng Fan;  Youlin Luo;  Shan Li;  Dagang Yuan;  Bin Zhao;  Qi Tao;  Changquan Wang;  Bing Li;  Xuesong Gao;  Yiding Li;  Huanxiu Li;  John P. Wilson
收藏  |  浏览/下载:8/0  |  提交时间:2020/05/13
Structure and mechanism of human diacylglycerol O-acyltransferase 1 期刊论文
NATURE, 2020, 581 (7808) : 329-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/03

The structure of human diacylglycerol O-acyltransferase 1, a membrane protein that synthesizes triacylglycerides, is solved with cryo-electron microscopy, providing insight into its function and mechanism of enzymatic activity.


Diacylglycerol O-acyltransferase 1 (DGAT1) synthesizes triacylglycerides and is required for dietary fat absorption and fat storage in humans(1). DGAT1 belongs to the membrane-bound O-acyltransferase (MBOAT) superfamily, members of which are found in all kingdoms of life and are involved in the acylation of lipids and proteins(2,3). How human DGAT1 and other mammalian members of the MBOAT family recognize their substrates and catalyse their reactions is unknown. The absence of three-dimensional structures also hampers rational targeting of DGAT1 for therapeutic purposes. Here we present the cryo-electron microscopy structure of human DGAT1 in complex with an oleoyl-CoA substrate. Each DGAT1 protomer has nine transmembrane helices, eight of which form a conserved structural fold that we name the MBOAT fold. The MBOAT fold in DGAT1 forms a hollow chamber in the membrane that encloses highly conserved catalytic residues. The chamber has separate entrances for each of the two substrates, fatty acyl-CoA and diacylglycerol. DGAT1 can exist as either a homodimer or a homotetramer and the two forms have similar enzymatic activity. The N terminus of DGAT1 interacts with the neighbouring protomer and these interactions are required for enzymatic activity.


  
The online competition between pro- and anti-vaccination views 期刊论文
NATURE, 2020, 582 (7811) : 230-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

Insights into the interactions between pro- and anti-vaccination clusters on Facebook can enable policies and approaches that attempt to interrupt the shift to anti-vaccination views and persuade undecided individuals to adopt a pro-vaccination stance.


Distrust in scientific expertise(1-14) is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks(2-4), as happened for measles in 2019(5,6). Homemade remedies(7,8) and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice(9-11). There is a lack of understanding about how this distrust evolves at the system level(13,14). Here we provide a map of the contention surrounding vaccines that has emerged from the global pool of around three billion Facebook users. Its core reveals a multi-sided landscape of unprecedented intricacy that involves nearly 100 million individuals partitioned into highly dynamic, interconnected clusters across cities, countries, continents and languages. Although smaller in overall size, anti-vaccination clusters manage to become highly entangled with undecided clusters in the main online network, whereas pro-vaccination clusters are more peripheral. Our theoretical framework reproduces the recent explosive growth in anti-vaccination views, and predicts that these views will dominate in a decade. Insights provided by this framework can inform new policies and approaches to interrupt this shift to negative views. Our results challenge the conventional thinking about undecided individuals in issues of contention surrounding health, shed light on other issues of contention such as climate change(11), and highlight the key role of network cluster dynamics in multi-species ecologies(15).


  
Impact of anthropogenic emissions on biogenic secondary organic aerosol: observation in the Pearl River Delta, southern China 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (22) : 14403-14415
作者:  Zhang, Yu-Qing;  Chen, Duo-Hong;  Ding, Xiang;  Li, Jun;  Zhang, Tao;  Wang, Jun-Qi;  Cheng, Qian;  Jiang, Hao;  Song, Wei;  Ou, Yu-Bo;  Ye, Peng-Lin;  Zhang, Gan;  Wang, Xin-Ming
收藏  |  浏览/下载:12/0  |  提交时间:2020/02/17
Giant anisotropic thermal expansion actuated by thermodynamically assisted reorientation of imidazoliums in a single crystal 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Yao, Zi-Shuo;  Guan, Hanxi;  Shiota, Yoshihito;  He, Chun-Ting;  Wang, Xiao-Lei;  Wu, Shu-Qi;  Zheng, Xiaoyan;  Su, Sheng-Qun;  Yoshizawa, Kazunari;  Kong, Xueqian;  Sato, Osamu;  Tao, Jun
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Model evaluation and intercomparison of surface-level ozone and relevant species in East Asia in the context of MICS-Asia Phase III - Part 1: Overview 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (20) : 12993-13015
作者:  Li, Jie;  Nagashima, Tatsuya;  Kong, Lei;  Ge, Baozhu;  Yamaji, Kazuyo;  Fu, Joshua S.;  Wang, Xuemei;  Fan, Qi;  Itahashi, Syuichi;  Lee, Hyo-Jung;  Kim, Cheol-Hee;  Lin, Chuan-Yao;  Zhang, Meigen;  Tao, Zhining;  Kajino, Mizuo;  Liao, Hong;  Li, Meng;  Woo, Jung-Hun;  Kurokawa, Jun-ichi;  Wang, Zhe;  Wu, Qizhong;  Akimoto, Hajime;  Carmichael, Gregory R.;  Wang, Zifa
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
Molecular doping enabled scalable blading of efficient hole-transport-layer-free perovskite solar cells 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Wu, Wu-Qiang;  Wang, Qi;  Fang, Yanjun;  Shao, Yuchuan;  Tang, Shi;  Deng, Yehao;  Lu, Haidong;  Liu, Ye;  Li, Tao;  Yang, Zhibin;  Gruverman, Alexei;  Huang, Jinsong
收藏  |  浏览/下载:18/0  |  提交时间:2019/11/27