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A new divergence method to quantify methane emissions using observations of Sentinel-5P TROPOMI 期刊论文
Geophysical Research Letters, 2021
作者:  Mengyao Liu;  Ronald van der A;  Michiel van Weele;  Henk Eskes;  Xiao Lu;  Pepijn Veefkind;  Jos de Laat;  Hao Kong;  Jingxu Wang;  Jiyunting Sun;  Jieying Ding;  Yuanhong Zhao;  Hongjian Weng
收藏  |  浏览/下载:16/0  |  提交时间:2021/10/07
The underappreciated role of agricultural soil nitrogen oxide emissions in ozone pollution regulation in North China 期刊论文
Nature Communications, 2021
作者:  Lu, Xiao;  Ye, Xingpei;  Zhou, Mi;  Zhao, Yuanhong;  Weng, Hongjian;  Kong, Hao;  Li, Ke;  Gao, Meng;  Zheng, Bo;  Lin, Jintai;  Zhou, Feng;  Zhang, Qiang;  Wu, Dianming;  Zhang, Lin;  Zhang, Yuanhang
收藏  |  浏览/下载:21/0  |  提交时间:2021/08/25
Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat 期刊论文
Science, 2020
作者:  Hongwei Wang;  Silong Sun;  Wenyang Ge;  Lanfei Zhao;  Bingqian Hou;  Kai Wang;  Zhongfan Lyu;  Liyang Chen;  Shoushen Xu;  Jun Guo;  Min Li;  Peisen Su;  Xuefeng Li;  Guiping Wang;  Cunyao Bo;  Xiaojian Fang;  Wenwen Zhuang;  Xinxin Cheng;  Jianwen Wu;  Luhao Dong;  Wuying Chen;  Wen Li;  Guilian Xiao;  Jinxiao Zhao;  Yongchao Hao;  Ying Xu;  Yu Gao;  Wenjing Liu;  Yanhe Liu;  Huayan Yin;  Jiazhu Li;  Xiang Li;  Yan Zhao;  Xiaoqian Wang;  Fei Ni;  Xin Ma;  Anfei Li;  Steven S. Xu;  Guihua Bai;  Eviatar Nevo;  Caixia Gao;  Herbert Ohm;  Lingrang Kong
收藏  |  浏览/下载:15/0  |  提交时间:2020/05/25
A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage (vol 551, pg 629, 2017) 期刊论文
NATURE, 2020, 580 (7802) : E5-E5
作者:  Lu, Zhihao;  Zou, Jianling;  Li, Shuang;  Topper, Michael J.;  Tao, Yong;  Zhang, Hao;  Jiao, Xi;  Xie, Wenbing;  Kong, Xiangqian;  Vaz, Michelle;  Li, Huili;  Cai, Yi;  Xia, Limin;  Huang, Peng;  Rodgers, Kristen;  Lee, Beverly;  Riemer, Joanne B.;  Day, Chi-Ping;  Yen, Ray-Whay Chiu;  Cui, Ying;  Wang, Yujiao;  Wang, Yanni;  Zhang, Weiqiang;  Easwaran, Hariharan;  Hulbert, Alicia;  Kim, KiBem;  Juergens, Rosalyn A.;  Yang, Stephen C.;  Battafarano, Richard J.;  Bush, Errol L.;  Broderick, Stephen R.;  Cattaneo, Stephen M.;  Brahmer, Julie R.;  Rudin, Charles M.;  Wrangle, John;  Mei, Yuping;  Kim, Young J.;  Zhang, Bin;  Wang, Ken Kang-Hsin;  Forde, Patrick M.;  Margolick, Joseph B.;  Nelkin, Barry D.;  Zahnow, Cynthia A.;  Pardoll, Drew M.;  Housseau, Franck;  Baylin, Stephen B.;  Shen, Lin;  Brock, Malcolm V.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/03
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation 期刊论文
NATURE, 2020, 580 (7803) : 391-+
作者:  Zhang, Zhibin;  Zhang, Ying;  Xia, Shiyu;  Kong, Qing;  Li, Shunying;  Liu, Xing;  Junqueira, Caroline;  Meza-Sosa, Karla F.;  Mok, Temy Mo Yin;  Ansara, James;  Sengupta, Satyaki;  Yao, Yandan;  Wu, Hao;  Lieberman, Judy
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

The biological function of Z-DNA and Z-RNA, nucleic acid structures with a left-handed double helix, is poorly understood(1-3). Z-DNA-binding protein 1 (ZBP1  also known as DAI or DLM-1) is a nucleic acid sensor that contains two Z alpha domains that bind Z-DNA(4,5) and Z-RNA(6-8). ZBP1 mediates host defence against some viruses(6,7,9-14) by sensing viral nucleic acids(6,7,10). RIPK1 deficiency, or mutation of its RIP homotypic interaction motif (RHIM), triggers ZBP1-dependent necroptosis and inflammation in mice(15,16). However, the mechanisms that induce ZBP1 activation in the absence of viral infection remain unknown. Here we show that Z alpha-dependent sensing of endogenous ligands induces ZBP1-mediated perinatal lethality in mice expressing RIPK1 with mutated RHIM (Ripk1(mR/mR)), skin inflammation in mice with epidermis-specific RIPK1 deficiency (RIPK1(E-KO)) and colitis in mice with intestinal epithelial-specific FADD deficiency (FADD(IEC-KO)). Consistently, functional Z alpha domains were required for ZBP1-induced necroptosis in fibroblasts that were treated with caspase inhibitors or express RIPK1 with mutated RHIM. Inhibition of nuclear export triggered the Z alpha-dependent activation of RIPK3 in the nucleus resulting in cell death, which suggests that ZBP1 may recognize nuclear Z-form nucleic acids. We found that ZBP1 constitutively bound cellular double-stranded RNA in a Z alpha-dependent manner. Complementary reads derived from endogenous retroelements were detected in epidermal RNA, which suggests that double-stranded RNA derived from these retroelements may act as a Z alpha-domain ligand that triggers the activation of ZBP1. Collectively, our results provide evidence that the sensing of endogenous Z-form nucleic acids by ZBP1 triggers RIPK3-dependent necroptosis and inflammation, which could underlie the development of chronic inflammatory conditions-particularly in individuals with mutations in RIPK1 and CASP8(17-20).


  
Nightside condensation of iron in an ultrahot giant exoplanet 期刊论文
NATURE, 2020, 580 (7805) : 597-+
作者:  Lu, Zhihao;  Zou, Jianling;  Li, Shuang;  Topper, Michael J.;  Tao, Yong;  Zhang, Hao;  Jiao, Xi;  Xie, Wenbing;  Kong, Xiangqian;  Vaz, Michelle;  Li, Huili;  Cai, Yi;  Xia, Limin;  Huang, Peng;  Rodgers, Kristen;  Lee, Beverly;  Riemer, Joanne B.;  Day, Chi-Ping;  Yen, Ray-Whay Chiu;  Cui, Ying;  Wang, Yujiao;  Wang, Yanni;  Zhang, Weiqiang;  Easwaran, Hariharan;  Hulbert, Alicia;  Kim, KiBem;  Juergens, Rosalyn A.;  Yang, Stephen C.;  Battafarano, Richard J.;  Bush, Errol L.;  Broderick, Stephen R.;  Cattaneo, Stephen M.;  Brahmer, Julie R.;  Rudin, Charles M.;  Wrangle, John;  Mei, Yuping;  Kim, Young J.;  Zhang, Bin;  Wang, Ken Kang-Hsin;  Forde, Patrick M.;  Margolick, Joseph B.;  Nelkin, Barry D.;  Zahnow, Cynthia A.;  Pardoll, Drew M.;  Housseau, Franck;  Baylin, Stephen B.;  Shen, Lin;  Brock, Malcolm V.
收藏  |  浏览/下载:57/0  |  提交时间:2020/07/03

Ultrahot giant exoplanets receive thousands of times Earth'  s insolation(1,2). Their high-temperature atmospheres (greater than 2,000 kelvin) are ideal laboratories for studying extreme planetary climates and chemistry(3-5). Daysides are predicted to be cloud-free, dominated by atomic species(6) and much hotter than nightsides(5,7,8). Atoms are expected to recombine into molecules over the nightside(9), resulting in different day and night chemistries. Although metallic elements and a large temperature contrast have been observed(10-14), no chemical gradient has been measured across the surface of such an exoplanet. Different atmospheric chemistry between the day-to-night ('  evening'  ) and night-to-day ('  morning'  ) terminators could, however, be revealed as an asymmetric absorption signature during transit(4,7,15). Here we report the detection of an asymmetric atmospheric signature in the ultrahot exoplanet WASP-76b. We spectrally and temporally resolve this signature using a combination of high-dispersion spectroscopy with a large photon-collecting area. The absorption signal, attributed to neutral iron, is blueshifted by -11 +/- 0.7 kilometres per second on the trailing limb, which can be explained by a combination of planetary rotation and wind blowing from the hot dayside(16). In contrast, no signal arises from the nightside close to the morning terminator, showing that atomic iron is not absorbing starlight there. We conclude that iron must therefore condense during its journey across the nightside.


Absorption lines of iron in the dayside atmosphere of an ultrahot giant exoplanet disappear after travelling across the nightside, showing that the iron has condensed during its travel.


  
Carbon and health implications of trade restrictions 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Lin, Jintai;  Du, Mingxi;  Chen, Lulu;  Feng, Kuishuang;  Liu, Yu;  Martin, Randall, V;  Wang, Jingxu;  Ni, Ruijing;  Zhao, Yu;  Kong, Hao;  Weng, Hongjian;  Liu, Mengyao;  van Donkelaar, Aaron;  Liu, Qiuyu;  Hubacek, Klaus
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
High-resolution (0.05 degrees x 0.05 degrees) NOx emissions in the Yangtze River Delta inferred from OMI 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (20) : 12835-12856
作者:  Kong, Hao;  Lin, Jintai;  Zhang, Ruixiong;  Liu, Mengyao;  Weng, Hongjian;  Ni, Ruijing;  Chen, Lulu;  Wang, Jingxu;  Yan, Yingying;  Zhang, Qiang
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Byun, Sangwon;  Kim, Dong-Hyun;  Ryerson, Daniel;  Kim, Young-Chae;  Sun, Hao;  Kong, Bo;  Yau, Peter;  Guo, Grace;  Xu, H. Eric;  Kemper, Byron;  Kemper, Jongsook Kim
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/27
Effect of N addition on home-field advantage of litter decomposition in subtropical forests 期刊论文
FOREST ECOLOGY AND MANAGEMENT, 2017, 398
作者:  Lin, Hong;  He, Zaihua;  Hao, Jiewei;  Tian, Kai;  Jia, Xiuqin;  Kong, Xiangshi;  Akbar, Siddiq;  Bei, Zhanlin;  Tian, Xingjun
收藏  |  浏览/下载:6/0  |  提交时间:2019/04/09
Home-field advantage  Litter decomposition  Subtropical forests  Specialization  Nitrogen cycling