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Hydrological control of river and seawater lithium isotopes 期刊论文
Nature Communications, 2022
作者:  Zhang, Fei;  Dellinger, Mathieu;  Hilton, Robert G.;  Yu, Jimin;  Allen, Mark B.;  Densmore, Alexander L.;  Sun, Hui;  Jin, Zhangdong
收藏  |  浏览/下载:14/0  |  提交时间:2022/06/24
Tropical tall forests are more sensitive and vulnerable to drought than short forests 期刊论文
Global Change Biology, 2021
作者:  Liyang Liu;  Xiuzhi Chen;  Philippe Ciais;  Wenping Yuan;  Fabienne Maignan;  Jin Wu;  Shilong Piao;  Ying-Ping Wang;  Jean-Pierre Wigneron;  Lei Fan;  Pierre Gentine;  Xueqin Yang;  Fanxi Gong;  Hui Liu;  Chen Wang;  Xuli Tang;  Hui Yang;  Qing Ye;  Bin He;  Jiali Shang;  Yongxian Su
收藏  |  浏览/下载:16/0  |  提交时间:2021/12/15
Greenness Surrounding Schools and Visual Impairment in Chinese Children and Adolescents 期刊论文
Environmental Health Perspectives, 2021
作者:  Bo-Yi Yang;  Shanshan Li;  Zhiyong Zou;  Iana Markevych;  Joachim Heinrich;  Michael S. Bloom;  Ya-Na Luo;  Wen-Zhong Huang;  Xiang Xiao;  Zhaohuan Gui;  Wen-Wen Bao;  Jin Jing;  Jun Ma;  Yinghua Ma;  Yajun Chen;  Guang-Hui Dong
收藏  |  浏览/下载:18/0  |  提交时间:2021/11/15
Quantum walks on a programmable two-dimensional 62-qubit superconducting processor 期刊论文
Science, 2021
作者:  Ming Gong;  Shiyu Wang;  Chen Zha;  Ming-Cheng Chen;  He-Liang Huang;  Yulin Wu;  Qingling Zhu;  Youwei Zhao;  Shaowei Li;  Shaojun Guo;  Haoran Qian;  Yangsen Ye;  Fusheng Chen;  Chong Ying;  Jiale Yu;  Daojin Fan;  Dachao Wu;  Hong Su;  Hui Deng;  Hao Rong;  Kaili Zhang;  Sirui Cao;  Jin Lin;  Yu Xu;  Lihua Sun;  Cheng Guo;  Na Li;  Futian Liang;  V. M. Bastidas;  Kae Nemoto;  W. J. Munro;  Yong-Heng Huo;  Chao-Yang Lu;  Cheng-Zhi Peng;  Xiaobo Zhu;  Jian-Wei Pan
收藏  |  浏览/下载:16/0  |  提交时间:2021/06/07
Realization of an ideal Weyl semimetal band in a quantum gas with 3D spin-orbit coupling 期刊论文
Science, 2021
作者:  Zong-Yao Wang;  Xiang-Can Cheng;  Bao-Zong Wang;  Jin-Yi Zhang;  Yue-Hui Lu;  Chang-Rui Yi;  Sen Niu;  Youjin Deng;  Xiong-Jun Liu;  Shuai Chen;  Jian-Wei Pan
收藏  |  浏览/下载:13/0  |  提交时间:2021/04/20
Multiple constraints cause positive and negative feedbacks limiting grassland soil CO2 efflux under CO2 enrichment 期刊论文
Proceedings of the National Academy of Sciences, 2020
作者:  Philip A. Fay;  Dafeng Hui;  Robert B. Jackson;  Harold P. Collins;  Lara G. Reichmann;  Michael J. Aspinwall;  Virginia L. Jin;  Albina R. Khasanova;  Robert W. Heckman;  H. Wayne Polley
收藏  |  浏览/下载:11/0  |  提交时间:2020/12/28
Distinct aerosol effects on cloud-to-ground lightning in the plateau and basin regions of Sichuan, Southwest China 期刊论文
Atmospheric Chemistry and Physics, 2020
作者:  Pengguo Zhao, Zhanqing Li, Hui Xiao, Fang Wu, Youtong Zheng, Maureen C. Cribb, Xiaoai Jin, and Yunjun Zhou
收藏  |  浏览/下载:6/0  |  提交时间:2020/06/22
Injured adult neurons regress to an embryonic transcriptional growth state 期刊论文
NATURE, 2020, 581 (7806) : 77-+
作者:  Wang, Ruicong;  Li, Hongda;  Wu, Jianfeng;  Cai, Zhi-Yu;  Li, Baizhou;  Ni, Hengxiao;  Qiu, Xingfeng;  Chen, Hui;  Liu, Wei;  Yang, Zhang-Hua;  Liu, Min;  Hu, Jin;  Liang, Yaoji;  Lan, Ping;  Han, Jiahuai;  Mo, Wei
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/03

Grafts of spinal-cord-derived neural progenitor cells (NPCs) enable the robust regeneration of corticospinal axons and restore forelimb function after spinal cord injury(1)  however, the molecular mechanisms that underlie this regeneration are unknown. Here we perform translational profiling specifically of corticospinal tract (CST) motor neurons in mice, to identify their '  regenerative transcriptome'  after spinal cord injury and NPC grafting. Notably, both injury alone and injury combined with NPC grafts elicit virtually identical early transcriptomic responses in host CST neurons. However, in mice with injury alone this regenerative transcriptome is downregulated after two weeks, whereas in NPC-grafted mice this transcriptome is sustained. The regenerative transcriptome represents a reversion to an embryonic transcriptional state of the CST neuron. The huntingtin gene (Htt) is a central hub in the regeneration transcriptome  deletion of Htt significantly attenuates regeneration, which shows that Htt has a key role in neural plasticity after injury.


In mouse models of central nervous system injury, Htt is shown to be a key component of the regulatory program associated with reversion of the neuronal transcriptome to a less-mature state.


  
The gut-brain axis mediates sugar preference 期刊论文
NATURE, 2020, 580 (7804) : 511-+
作者:  Wang, Ruicong;  Li, Hongda;  Wu, Jianfeng;  Cai, Zhi-Yu;  Li, Baizhou;  Ni, Hengxiao;  Qiu, Xingfeng;  Chen, Hui;  Liu, Wei;  Yang, Zhang-Hua;  Liu, Min;  Hu, Jin;  Liang, Yaoji;  Lan, Ping;  Han, Jiahuai;  Mo, Wei
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/03

The taste of sugar is one of the most basic sensory percepts for humans and other animals. Animals can develop a strong preference for sugar even if they lack sweet taste receptors, indicating a mechanism independent of taste(1-3). Here we examined the neural basis for sugar preference and demonstrate that a population of neurons in the vagal ganglia and brainstem are activated via the gut-brain axis to create preference for sugar. These neurons are stimulated in response to sugar but not artificial sweeteners, and are activated by direct delivery of sugar to the gut. Using functional imaging we monitored activity of the gut-brain axis, and identified the vagal neurons activated by intestinal delivery of glucose. Next, we engineered mice in which synaptic activity in this gut-to-brain circuit was genetically silenced, and prevented the development of behavioural preference for sugar. Moreover, we show that co-opting this circuit by chemogenetic activation can create preferences to otherwise less-preferred stimuli. Together, these findings reveal a gut-to-brain post-ingestive sugar-sensing pathway critical for the development of sugar preference. In addition, they explain the neural basis for differences in the behavioural effects of sweeteners versus sugar, and uncover an essential circuit underlying the highly appetitive effects of sugar.


Experiments in mice show that a population of neurons in the vagal ganglia respond to the presence of glucose in the gut and connect to neurons in the brainstem, revealing the circuit that underlies the neural basis for the behavioural preference for sugar.


  
Electrical manipulation of a topological antiferromagnetic state 期刊论文
NATURE, 2020, 580 (7805) : 608-+
作者:  Chabon, Jacob J.;  Hamilton, Emily G.;  Kurtz, David M.;  Esfahani, Mohammad S.;  Moding, Everett J.;  Stehr, Henning;  Schroers-Martin, Joseph;  Nabet, Barzin Y.;  Chen, Binbin;  Chaudhuri, Aadel A.;  Liu, Chih Long;  Hui, Angela B.;  Jin, Michael C.;  Azad, Tej D.;  Almanza, Diego;  Jeon, Young-Jun;  Nesselbush, Monica C.;  Keh, Lyron Co Ting;  Bonilla, Rene F.;  Yoo, Christopher H.;  Ko, Ryan B.;  Chen, Emily L.;  Merriott, David J.;  Massion, Pierre P.;  Mansfield, Aaron S.;  Jen, Jin;  Ren, Hong Z.;  Lin, Steven H.;  Costantino, Christina L.;  Burr, Risa;  Tibshirani, Robert;  Gambhir, Sanjiv S.;  Berry, Gerald J.;  Jensen, Kristin C.;  West, Robert B.;  Neal, Joel W.;  Wakelee, Heather A.;  Loo, Billy W., Jr.;  Kunder, Christian A.;  Leung, Ann N.;  Lui, Natalie S.;  Berry, Mark F.;  Shrager, Joseph B.;  Nair, Viswam S.;  Haber, Daniel A.;  Sequist, Lecia V.;  Alizadeh, Ash A.;  Diehn, Maximilian
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/03

Room-temperature electrical switching of a topological antiferromagnetic state in polycrystalline Mn3Sn thin films is demonstrated using the same protocol as that used for conventional ferromagnetic metals.


Electrical manipulation of phenomena generated by nontrivial band topology is essential for the development of next-generation technology using topological protection. A Weyl semimetal is a three-dimensional gapless system that hosts Weyl fermions as low-energy quasiparticles(1-4). It has various exotic properties, such as a large anomalous Hall effect (AHE) and chiral anomaly, which are robust owing to the topologically protected Weyl nodes(1-16). To manipulate such phenomena, a magnetic version of Weyl semimetals would be useful for controlling the locations of Weyl nodes in the Brillouin zone. Moreover, electrical manipulation of antiferromagnetic Weyl metals would facilitate the use of antiferromagnetic spintronics to realize high-density devices with ultrafast operation(17,18). However, electrical control of a Weyl metal has not yet been reported. Here we demonstrate the electrical switching of a topological antiferromagnetic state and its detection by the AHE at room temperature in a polycrystalline thin film(19) of the antiferromagnetic Weyl metal Mn3Sn9,10,12,20, which exhibits zero-field AHE. Using bilayer devices composed of Mn3Sn and nonmagnetic metals, we find that an electrical current density of about 10(10) to 10(11) amperes per square metre induces magnetic switching in the nonmagnetic metals, with a large change in Hall voltage. In addition, the current polarity along the bias field and the sign of the spin Hall angle of the nonmagnetic metals-positive for Pt (ref. (21)), close to 0 for Cu and negative for W (ref. (22))-determines the sign of the Hall voltage. Notably, the electrical switching in the antiferromagnet is achieved with the same protocol as that used for ferromagnetic metals(23,24). Our results may lead to further scientific and technological advances in topological magnetism and antiferromagnetic spintronics.