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Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target 期刊论文
SCIENCE, 2019, 365 (6456) : 884-+
作者:  Alam, Mahmood M.;  Sanchez-Azqueta, Ana;  Janha, Omar;  Flannery, Erika L.;  Mahindra, Amit;  Mapesa, Kopano;  Char, Aditya B.;  Sriranganadane, Dev;  Brancucci, Nicolas M. B.;  Antonova-Koch, Yevgeniya;  Crouch, Kathryn;  Simwela, Nelson Victor;  Millar, Scott B.;  Akinwale, Jude;  Mitcheson, Deborah;  Solyakov, Lev;  Dudek, Kate;  Jones, Carolyn;  Zapatero, Cleofe;  Doerig, Christian;  Nwakanma, Davis C.;  Jesus Vazquez, Maria;  Colmenarejo, Gonzalo;  Jose Lafuente-Monasterio, Maria;  Luisa Leon, Maria;  Godoi, Paulo H. C.;  Elkins, Jon M.;  Waters, Andrew P.;  Jamieson, Andrew G.;  Fernandez Alvaro, Elena;  Ranford-Cartwright, Lisa C.;  Marti, Matthias;  Winzeler, Elizabeth A.;  Javier Gamo, Francisco;  Tobin, Andrew B.
收藏  |  浏览/下载：8/0  |  提交时间：2019/11/27
A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Baker, David A.;  Stewart, Lindsay B.;  Large, Jonathan M.;  Bowyer, Paul W.;  Ansell, Keith H.;  Jimenez-Diaz, Mar-A B.;  El Bakkouri, Majida;  Birchall, Kristian;  Dechering, Koen J.;  Bouloc, Nathalie S.;  Coombs, Peter J.;  Whalley, David;  Harding, Denise J.;  Smiljanic-Hurley, Ela;  Wheldon, Mary C.;  Walker, Eloise M.;  Dessens, Johannes T.;  Lafuente, Maria Jose;  Sanz, Laura M.;  Gamo, Francisco-Javier;  Ferrer, Santiago B.;  Hui, Raymond;  Bousema, Teun;  Angulo-Barturen, I. Igo;  Merritt, Andy T.;  Croft, Simon L.;  Gutteridge, Winston E.;  Kettleborough, Catherine A.;  Osborne, Simon A.
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials 期刊论文
SCIENCE, 2018, 362 (6419)
作者:  Antonova-Koch, Yevgeniya;  Meister, Stephan;  Abraham, Matthew;  Luth, Madeline R.;  Ottilie, Sabine;  Lukens, Amanda K.;  Sakata-Kato, Tomoyo;  Vanaerschot, Manu;  Owen, Edward;  Rodriguez, Juan Carlos Jado;  Maher, Steven P.;  Calla, Jaeson;  Plouffe, David;  Zhong, Yang;  Chen, Kaisheng;  Chaumeau, Victor;  Conway, Amy J.;  McNamara, Case W.;  Ibanez, Maureen;  Gagaring, Kerstin;  Neria Serrano, Fernando;  Eribez, Korina;  Taggard, Cullin McLean;  Cheung, Andrea L.;  Lincoln, Christie;  Ambachew, Biniam;  Rouillier, Melanie;  Siegel, Dionicio;  Nosten, Francois;  Kyle, Dennis E.;  Gamo, Francisco-Javier;  Zhou, Yingyao;  Llinas, Manuel;  Fidock, David A.;  Wirth, Dyann F.;  Burrows, Jeremy;  Campo, Brice;  Winzeler, Elizabeth A.
收藏  |  浏览/下载：16/0  |  提交时间：2019/11/27
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics 期刊论文
SCIENCE, 2018, 359 (6372) : 191-+
作者:  Cowell, Annie N.;  Istvan, Eva S.;  Lukens, Amanda K.;  Gomez-Lorenzo, Maria G.;  Vanaerschot, Manu;  Sakata-Kato, Tomoyo;  Flannery, Erika L.;  Magistrado, Pamela;  Owen, Edward;  Abraham, Matthew;  LaMonte, Gregory;  Painter, Heather J.;  Williams, Roy M.;  Franco, Virginia;  Linares, Maria;  Arriaga, Ignacio;  Bopp, Selina;  Corey, Victoria C.;  Gnadig, Nina F.;  Coburn-Flynn, Olivia;  Reimer, Christin;  Gupta, Purva;  Murithi, James M.;  Moura, Pedro A.;  Fuchs, Olivia;  Sasaki, Erika;  Kim, Sang W.;  Teng, Christine H.;  Wang, Lawrence T.;  Akidil, Asli;  Adjalley, Sophie;  Willis, Paul A.;  Siegel, Dionicio;  Tanaseichuk, Olga;  Zhong, Yang;  Zhou, Yingyao;  Llinas, Manuel;  Ottilie, Sabine;  Gamo, Francisco-Javier;  Lee, Marcus C. S.;  Goldberg, Daniel E.;  Fidock, David A.;  Wirth, Dyann F.;  Winzeler, Elizabeth A.
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/27