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Demographic composition, not demographic diversity, predicts biomass and turnover across temperate and tropical forests 期刊论文
Global Change Biology, 2022
作者:  Jessica F. Needham;  Daniel J. Johnson;  Kristina J. Anderson-Teixeira;  Norman Bourg;  Sarayudh Bunyavejchewin;  Nathalie Butt;  Min Cao;  Dairon Cá;  rdenas;  Chia-Hao Chang-Yang;  Yu-Yun Chen;  George Chuyong;  Handanakere S. Dattaraja;  Stuart J. Davies;  Alvaro Duque;  Corneille E. N. Ewango;  Edwino S. Fernando;  Rosie Fisher;  Christine D. Fletcher;  Robin Foster;  Zhanqing Hao;  Terese Hart;  Chang-Fu Hsieh;  Stephen P. Hubbell;  Akira Itoh;  David Kenfack;  Charles D. Koven;  Andrew J. Larson;  James A. Lutz;  William McShea;  Jean-Remy Makana;  Yadvinder Malhi;  Toby Marthews;  Mohizah Bt. Mohamad;  Michael D. Morecroft;  Natalia Norden;  Geoffrey Parker;  Ankur Shringi;  Raman Sukumar;  Hebbalalu S. Suresh;  I-Fang Sun;  Sylvester Tan;  Duncan W. Thomas;  Jill Thompson;  Maria Uriarte;  Renato Valencia;  Tze Leong Yao;  Sandra L. Yap;  Zuoqiang Yuan;  Hu Yuehua;  Jess K. Zimmerman;  Daniel Zuleta;  Sean M. McMahon
收藏  |  浏览/下载：16/0  |  提交时间：2022/02/23
SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model 期刊论文
Science, 2021
作者:  Jingxin Qiao;  Yue-Shan Li;  Rui Zeng;  Feng-Liang Liu;  Rong-Hua Luo;  Chong Huang;  Yi-Fei Wang;  Jie Zhang;  Baoxue Quan;  Chenjian Shen;  Xin Mao;  Xinlei Liu;  Weining Sun;  Wei Yang;  Xincheng Ni;  Kai Wang;  Ling Xu;  Zi-Lei Duan;  Qing-Cui Zou;  Hai-Lin Zhang;  Wang Qu;  Yang-Hao-Peng Long;  Ming-Hua Li;  Rui-Cheng Yang;  Xiaolong Liu;  Jing You;  Yangli Zhou;  Rui Yao;  Wen-Pei Li;  Jing-Ming Liu;  Pei Chen;  Yang Liu;  Gui-Feng Lin;  Xin Yang;  Jun Zou;  Linli Li;  Yiguo Hu;  Guang-Wen Lu;  Wei-Min Li;  Yu-Quan Wei;  Yong-Tang Zheng;  Jian Lei;  Shengyong Yang
收藏  |  浏览/下载：13/0  |  提交时间：2021/04/06
WAVE2 suppresses mTOR activation to maintain T cell homeostasis and prevent autoimmunity 期刊论文
Science, 2021
作者:  Ming Liu;  Jinyi Zhang;  Benjamin D. Pinder;  Qingquan Liu;  Dingyan Wang;  Hao Yao;  Yubo Gao;  Aras Toker;  Jimin Gao;  Alan Peterson;  Jia Qu;  Katherine A. Siminovitch
收藏  |  浏览/下载：18/0  |  提交时间：2021/04/06
Near-surface softening and healing in eastern Honshu associated with the 2011 magnitude-9 Tohoku-Oki Earthquake 期刊论文
Nature Communications, 2021
作者:  Su-Yang Wang;  Hai-Yang Zhuang;  Hao Zhang;  Hong-Jun He;  Wei-Ping Jiang;  Er-Lei Yao;  Bin Ruan;  Yong-Xin Wu;  Yu Miao
收藏  |  浏览/下载：8/0  |  提交时间：2021/03/02
A comprehensive quantification of global nitrous oxide sources and sinks 期刊论文
Nature, 2020
作者:  Hanqin Tian;  Rongting Xu;  Josep G. Canadell;  Rona L. Thompson;  Wilfried Winiwarter;  Parvadha Suntharalingam;  Eric A. Davidson;  Philippe Ciais;  Robert B. Jackson;  Greet Janssens-Maenhout;  Michael J. Prather;  Pierre Regnier;  Naiqing Pan;  Shufen Pan;  Glen P. Peters;  Hao Shi;  Francesco N. Tubiello;  Sö;  nke Zaehle;  Feng Zhou;  Almut Arneth;  Gianna Battaglia;  Sarah Berthet;  Laurent Bopp;  Alexander F. Bouwman;  Erik T. Buitenhuis;  Jinfeng Chang;  Martyn P. Chipperfield;  Shree R. S. Dangal;  Edward Dlugokencky;  James W. Elkins;  Bradley D. Eyre;  Bojie Fu;  Bradley Hall;  Akihiko Ito;  Fortunat Joos;  Paul B. Krummel;  Angela Landolfi;  Goulven G. Laruelle;  Ronny Lauerwald;  Wei Li;  Sebastian Lienert;  Taylor Maavara;  Michael MacLeod;  Dylan B. Millet;  Stefan Olin;  Prabir K. Patra;  Ronald G. Prinn;  Peter A. Raymond;  Daniel J. Ruiz;  Guido R. van der Werf;  Nicolas Vuichard;  Junjie Wang;  Ray F. Weiss;  Kelley C. Wells;  Chris Wilson;  Jia Yang;  Yuanzhi Yao
收藏  |  浏览/下载：23/0  |  提交时间：2020/10/12
Plasmapause surface wave oscillates the magnetosphere and diffuse aurora 期刊论文
Nature, 2020
作者:  Fei He;  Rui-Long Guo;  William R. Dunn;  Zhong-Hua Yao;  Hua-Sen Zhang;  Yi-Xin Hao;  Quan-Qi Shi;  Zhao-Jin Rong;  Jiang Liu;  An-Min Tian;  Xiao-Xin Zhang;  Yong Wei;  Yong-Liang Zhang;  Qiu-Gang Zong;  Zu-Yin Pu;  Wei-Xing Wan
收藏  |  浏览/下载：13/0  |  提交时间：2020/05/13
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation 期刊论文
NATURE, 2020, 580 (7803) : 391-+
作者:  Zhang, Zhibin;  Zhang, Ying;  Xia, Shiyu;  Kong, Qing;  Li, Shunying;  Liu, Xing;  Junqueira, Caroline;  Meza-Sosa, Karla F.;  Mok, Temy Mo Yin;  Ansara, James;  Sengupta, Satyaki;  Yao, Yandan;  Wu, Hao;  Lieberman, Judy
收藏  |  浏览/下载：10/0  |  提交时间：2020/07/03

The biological function of Z-DNA and Z-RNA, nucleic acid structures with a left-handed double helix, is poorly understood(1-3). Z-DNA-binding protein 1 (ZBP1  also known as DAI or DLM-1) is a nucleic acid sensor that contains two Z alpha domains that bind Z-DNA(4,5) and Z-RNA(6-8). ZBP1 mediates host defence against some viruses(6,7,9-14) by sensing viral nucleic acids(6,7,10). RIPK1 deficiency, or mutation of its RIP homotypic interaction motif (RHIM), triggers ZBP1-dependent necroptosis and inflammation in mice(15,16). However, the mechanisms that induce ZBP1 activation in the absence of viral infection remain unknown. Here we show that Z alpha-dependent sensing of endogenous ligands induces ZBP1-mediated perinatal lethality in mice expressing RIPK1 with mutated RHIM (Ripk1(mR/mR)), skin inflammation in mice with epidermis-specific RIPK1 deficiency (RIPK1(E-KO)) and colitis in mice with intestinal epithelial-specific FADD deficiency (FADD(IEC-KO)). Consistently, functional Z alpha domains were required for ZBP1-induced necroptosis in fibroblasts that were treated with caspase inhibitors or express RIPK1 with mutated RHIM. Inhibition of nuclear export triggered the Z alpha-dependent activation of RIPK3 in the nucleus resulting in cell death, which suggests that ZBP1 may recognize nuclear Z-form nucleic acids. We found that ZBP1 constitutively bound cellular double-stranded RNA in a Z alpha-dependent manner. Complementary reads derived from endogenous retroelements were detected in epidermal RNA, which suggests that double-stranded RNA derived from these retroelements may act as a Z alpha-domain ligand that triggers the activation of ZBP1. Collectively, our results provide evidence that the sensing of endogenous Z-form nucleic acids by ZBP1 triggers RIPK3-dependent necroptosis and inflammation, which could underlie the development of chronic inflammatory conditions-particularly in individuals with mutations in RIPK1 and CASP8(17-20).


  
Increased global nitrous oxide emissions from streams and rivers in the Anthropocene 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (2) : 138-+
作者:  Yao, Yuanzhi;  Tian, Hanqin;  Shi, Hao;  Pan, Shufen;  Xu, Rongting;  Pan, Naiqing;  Canadell, Josep G.
收藏  |  浏览/下载：14/0  |  提交时间：2020/02/16
Ultrahigh-energy density lead-free dielectric films via polymorphic nanodomain design 期刊论文
SCIENCE, 2019, 365 (6453) : 578-582
作者:  Pan, Hao;  Li, Fei;  Liu, Yao;  Zhang, Qinghua;  Wang, Meng;  Lan, Shun;  Zheng, Yunpeng;  Ma, Jing;  Gu, Lin;  Shen, Yang;  Yu, Pu;  Zhang, Shujun;  Chen, Long-Qing;  Lin, Yuan-Hua;  Nan, Ce-Wen
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/27
Generation of multicomponent atomic Schrodinger cat states of up to 20 qubits 期刊论文
SCIENCE, 2019, 365 (6453) : 574-577
作者:  Song, Chao;  Xu, Kai;  Li, Hekang;  Zhang, Yu-Ran;  Zhang, Xu;  Liu, Wuxin;  Guo, Qiujiang;  Wang, Zhen;  Ren, Wenhui;  Hao, Jie;  Feng, Hui;  Fan, Heng;  Zheng, Dongning;  Wang, Da-Wei;  Wang, H.;  Zhu, Shi-Yao
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/27