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ECOSTRESS: NASA's Next Generation Mission to Measure Evapotranspiration From the International Space Station 期刊论文
WATER RESOURCES RESEARCH, 2020, 56 (4)
作者:  Fisher, Joshua B.;  Lee, Brian;  Purdy, Adam J.;  Halverson, Gregory H.;  Dohlen, Matthew B.;  Cawse-Nicholson, Kerry;  Wang, Audrey;  Anderson, Ray G.;  Aragon, Bruno;  Arain, M. Altaf;  Baldocchi, Dennis D.;  Baker, John M.;  Barral, Helene;  Bernacchi, Carl J.;  Bernhofer, Christian;  Biraud, Sebastien C.;  Bohrer, Gil;  Brunsell, Nathaniel;  Cappelaere, Bernard;  Castro-Contreras, Saulo;  Chun, Junghwa;  Conrad, Bryan J.;  Cremonese, Edoardo;  Demarty, Jerome;  Desai, Ankur R.;  De Ligne, Anne;  Foltynova, Lenka;  Goulden, Michael L.;  Griffis, Timothy J.;  Gruenwald, Thomas;  Johnson, Mark S.;  Kang, Minseok;  Kelbe, Dave;  Kowalska, Natalia;  Lim, Jong-Hwan;  Mainassara, Ibrahim;  McCabe, Matthew F.;  Missik, Justine E. C.;  Mohanty, Binayak P.;  Moore, Caitlin E.;  Morillas, Laura;  Morrison, Ross;  Munger, J. William;  Posse, Gabriela;  Richardson, Andrew D.;  Russell, Eric S.;  Ryu, Youngryel;  Sanchez-Azofeifa, Arturo;  Schmidt, Marius;  Schwartz, Efrat;  Sharp, Iain;  Sigut, Ladislav;  Tang, Yao;  Hulley, Glynn;  Anderson, Martha;  Hain, Christopher;  French, Andrew;  Wood, Eric;  Hook, Simon
收藏  |  浏览/下载：23/0  |  提交时间：2020/07/02
ECOSTRESS  eddy covariance  evapotranspiration  latent heat flux  satellite  validation  
Pharmacologic fibroblast reprogramming into photoreceptors restores vision 期刊论文
NATURE, 2020, 581 (7806) : 83-+
作者:  Jiang, Mingkai;  Medlyn, Belinda E.;  Drake, John E.;  Duursma, Remko A.;  Anderson, Ian C.;  Barton, Craig V. M.;  Boer, Matthias M.;  Carrillo, Yolima;  Castaneda-Gomez, Laura;  Collins, Luke;  Crous, Kristine Y.;  De Kauwe, Martin G.;  dos Santos, Bruna M.;  Emmerson, Kathryn M.;  Facey, Sarah L.;  Gherlenda, Andrew N.;  Gimeno, Teresa E.;  Hasegawa, Shun;  Johnson, Scott N.;  Kannaste, Astrid;  Macdonald, Catriona A.;  Mahmud, Kashif;  Moore, Ben D.;  Nazaries, Loic;  Neilson, Elizabeth H. J.;  Nielsen, Uffe N.;  Niinemets, Ulo;  Noh, Nam Jin;  Ochoa-Hueso, Raul;  Pathare, Varsha S.;  Pendall, Elise;  Pihlblad, Johanna;  Pineiro, Juan;  Powell, Jeff R.;  Power, Sally A.;  Reich, Peter B.;  Renchon, Alexandre A.;  Riegler, Markus;  Rinnan, Riikka;  Rymer, Paul D.;  Salomon, Roberto L.;  Singh, Brajesh K.;  Smith, Benjamin;  Tjoelker, Mark G.;  Walker, Jennifer K. M.;  Wujeska-Klause, Agnieszka;  Yang, Jinyan;  Zaehle, Soenke;  Ellsworth, David S.
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/03

Photoreceptor loss is the final common endpoint in most retinopathies that lead to irreversible blindness, and there are no effective treatments to restore vision(1,2). Chemical reprogramming of fibroblasts offers an opportunity to reverse vision loss  however, the generation of sensory neuronal subtypes such as photoreceptors remains a challenge. Here we report that the administration of a set of five small molecules can chemically induce the transformation of fibroblasts into rod photoreceptor-like cells. The transplantation of these chemically induced photoreceptor-like cells (CiPCs) into the subretinal space of rod degeneration mice (homozygous for rd1, also known as Pde6b) leads to partial restoration of the pupil reflex and visual function. We show that mitonuclear communication is a key determining factor for the reprogramming of fibroblasts into CiPCs. Specifically, treatment with these five compounds leads to the translocation of AXIN2 to the mitochondria, which results in the production of reactive oxygen species, the activation of NF-kappa B and the upregulation of Ascl1. We anticipate that CiPCs could have therapeutic potential for restoring vision.


A set of five small molecules can induce the transformation of fibroblasts into rod photoreceptor-like cells, which can partially restore pupil reflex and visual function when transplanted into a rod degeneration mouse model.


  
Embryonal precursors of Wilms tumor 期刊论文
SCIENCE, 2019, 366 (6470) : 1247-+
作者:  Coorens, Tim H. H.;  Treger, Taryn D.;  Al-Saadi, Reem;  Moore, Luiza;  Tran, Maxine G. B.;  Mitchell, Thomas J.;  Tugnait, Suzanne;  Thevanesan, Christine;  Young, Matthew D.;  Oliver, Thomas R. W.;  Oostveen, Minou;  Collord, Grace;  Tarpey, Patrick S.;  Cagan, Alex;  Hooks, Yvette;  Brougham, Mark;  Reynolds, Ben C.;  Barone, Giuseppe;  Anderson, John;  Jorgensen, Mette;  Burke, G. A. Amos;  Visser, Johannes;  Nicholson, James C.;  Smeulders, Naima;  Mushtaq, Imran;  Stewart, Grant D.;  Campbell, Peter J.;  Wedge, David C.;  Martincorena, Inigo;  Rampling, Dyanne;  Hook, Liz;  Warren, Anne Y.;  Coleman, Nicholas;  Chowdhury, Tanzina;  Sebire, Neil;  Drost, Jarno;  Saeb-Parsy, Kourosh;  Stratton, Michael R.;  Straathof, Karin;  Pritchard-Jones, Kathy;  Behjati, Sam
收藏  |  浏览/下载：10/0  |  提交时间：2020/02/17
Combining abundance and performance data reveals how temperature regulates coastal occurrences and activity of a roaming apex predator 期刊论文
GLOBAL CHANGE BIOLOGY, 2018, 24 (5) : 1884-1893
作者:  Payne, Nicholas L.;  Meyer, Carl G.;  Smith, James A.;  Houghton, Jonathan D. R.;  Barnett, Adam;  Holmes, Bonnie J.;  Nakamura, Itsumi;  Papastamatiou, Yannis P.;  Royer, Mark A.;  Coffey, Daniel M.;  Anderson, James M.;  Hutchinson, Melanie R.;  Sato, Katsufumi;  Halsey, Lewis G.
收藏  |  浏览/下载：8/0  |  提交时间：2019/04/09
accelerometer  biogeography  climate change  fundamental niche  overall dynamic body acceleration  physiological ecology  realized niche  species distribution modelling  tagging  thermal performance curve  
The SPARC water vapor assessment II: intercomparison of satellite and ground-based microwave measurements 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2017, 17 (23)
作者:  Nedoluha, Gerald E.;  Kiefer, Michael;  Lossow, Stefan;  Gomez, R. Michael;  Kampfer, Niklaus;  Lainer, Martin;  Forkman, Peter;  Christensen, Ole Martin;  Oh, Jung Jin;  Hartogh, Paul;  Anderson, John;  Bramstedt, Klaus;  Dinelli, Bianca M.;  Garcia-Comas, Maya;  Hervig, Mark;  Murtagh, Donal;  Raspollini, Piera;  Read, William G.;  Rosenlof, Karen;  Stiller, Gabriele P.;  Walker, Kaley A.
收藏  |  浏览/下载：9/0  |  提交时间：2019/04/09
Elevated CO2 does not increase eucalypt forest productivity on a low-phosphorus soil 期刊论文
NATURE CLIMATE CHANGE, 2017, 7 (4)
作者:  Ellsworth, David S.;  Anderson, Ian C.;  Crous, Kristine Y.;  Cooke, Julia;  Drake, John E.;  Gherlenda, Andrew N.;  Gimeno, Teresa E.;  Macdonald, Catriona A.;  Medlyn, Belinda E.;  Powell, Jeff R.;  Tjoelker, Mark G.;  Reich, Peter B.
收藏  |  浏览/下载：8/0  |  提交时间：2019/04/09
Global warming and recurrent mass bleaching of corals 期刊论文
NATURE, 2017, 543 (7645) : 373-+
作者:  Hughes, Terry P.;  Kerry, James T.;  Alvarez-Noriega, Mariana;  Alvarez-Romero, Jorge G.;  Anderson, Kristen D.;  Baird, Andrew H.;  Babcock, Russell C.;  Beger, Maria;  Bellwood, David R.;  Berkelmans, Ray;  Bridge, Tom C.;  Butler, Ian R.;  Byrne, Maria;  Cantin, Neal E.;  Comeau, Steeve;  Connolly, Sean R.;  Cumming, Graeme S.;  Dalton, Steven J.;  Diaz-Pulido, Guillermo;  Eakin, C. Mark;  Figueira, Will F.;  Gilmour, James P.;  Harrison, Hugo B.;  Heron, Scott F.;  Hoey, Andrew S.;  Hobbs, Jean-Paul A.;  Hoogenboom, Mia O.;  Kennedy, Emma V.;  Kuo, Chao-yang;  Lough, Janice M.;  Lowe, Ryan J.;  Liu, Gang;  Cculloch, Malcolm T. M.;  Malcolm, Hamish A.;  Mcwilliam, Michael J.;  Pandolfi, John M.;  Pears, Rachel J.;  Pratchett, Morgan S.;  Schoepf, Verena;  Simpson, Tristan;  Skirving, William J.;  Sommer, Brigitte;  Torda, Gergely;  Wachenfeld, David R.;  Willis, Bette L.;  Wilson, Shaun K.
收藏  |  浏览/下载：12/0  |  提交时间：2019/11/27
Integrated genomic and molecular characterization of cervical cancer 期刊论文
NATURE, 2017, 543 (7645) : 378-+
作者:  Burk, Robert D.;  Chen, Zigui;  Saller, Charles;  Tarvin, Katherine;  Carvalho, Andre L.;  Scapulatempo-Neto, Cristovam;  Silveira, Henrique C.;  Fregnani, Jose H.;  Creighton, Chad J.;  Anderson, Matthew L.;  Castro, Patricia;  Wang, Sophia S.;  Yau, Christina;  Benz, Christopher;  Robertson, A. Gordon;  Mungall, Karen;  Lim, Lynette;  Bowlby, Reanne;  Sadeghi, Sara;  Brooks, Denise;  Sipahimalani, Payal;  Mar, Richard;  Ally, Adrian;  Clarke, Amanda;  Mungall, Andrew J.;  Tam, Angela;  Lee, Darlene;  Chuah, Eric;  Schein, Jacqueline E.;  Tse, Kane;  Kasaian, Katayoon;  Ma, Yussanne;  Marra, Marco A.;  Mayo, Michael;  Balasundaram, Miruna;  Thiessen, Nina;  Dhalla, Noreen;  Carlsen, Rebecca;  Moore, Richard A.;  Holt, Robert A.;  Jones, Steven J. M.;  Wong, Tina;  Pantazi, Angeliki;  Parfenov, Michael;  Kucherlapati, Raju;  Hadjipanayis, Angela;  Seidman, Jonathan;  Kucherlapati, Melanie;  Ren, Xiaojia;  Xu, Andrew W.;  Yang, Lixing;  Park, Peter J.;  Lee, Semin;  Rabeno, Brenda;  Huelsenbeck-Dill, Lori;  Borowsky, Mark;  Cadungog, Mark;  Iacocca, Mary;  Petrelli, Nicholas;  Swanson, Patricia;  Ojesina, Akinyemi I.;  Le, Xuan;  Sandusky, George;  Adebamowo, Sally N.;  Akeredolu, Teniola;  Adebamowo, Clement;  Reynolds, Sheila M.;  Shmulevich, Ilya;  Shelton, Candace;  Crain, Daniel;  Mallery, David;  Curley, Erin;  Gardner, Johanna;  Penny, Robert;  Morris, Scott;  Shelton, Troy;  Liu, Jia;  Lolla, Laxmi;  Chudamani, Sudha;  Wu, Ye;  Birrer, Michael;  McLellan, Michael D.;  Bailey, Matthew H.;  Miller, Christopher A.;  Wyczalkowski, Matthew A.;  Fulton, Robert S.;  Fronick, Catrina C.;  Lu, Charles;  Mardis, Elaine R.;  Appelbaum, Elizabeth L.;  Schmidt, Heather K.;  Fulton, Lucinda A.;  Cordes, Matthew G.;  Li, Tiandao;  Ding, Li;  Wilson, Richard K.;  Rader, Janet S.;  Behmaram, Behnaz;  Uyar, Denise;  Bradley, William;  Wrangle, John;  Pastore, Alessandro;  Levine, Douglas A.;  Dao, Fanny;  Gao, Jianjiong;  Schultz, Nikolaus;  Sander, Chris;  Ladanyi, Marc;  Einstein, Mark;  Teeter, Randall;  Benz, Stephen;  Wentzensen, Nicolas;  Felau, Ina;  Zenklusen, Jean C.;  Bodelon, Clara;  Demchok, John A.;  Yang, Liming;  Sheth, Margi;  Ferguson, Martin L.;  Tarnuzzer, Roy;  Yang, Hannah;  Schiffman, Mark;  Zhang, Jiashan;  Wang, Zhining;  Davidsen, Tanja;  Olaniyan, Olayinka;  Hutter, Carolyn M.;  Sofia, Heidi J.;  Gordenin, Dmitry A.;  Chan, Kin;  Roberts, Steven A.;  Klimczak, Leszek J.;  Van Waes, Carter;  Chen, Zhong;  Saleh, Anthony D.;  Cheng, Hui;  Parfitt, Jeremy;  Bartlett, John;  Albert, Monique;  Arnaout, Angel;  Sekhon, Harman;  Gilbert, Sebastien;  Peto, Myron;  Myers, Jerome;  Harr, Jodi;  Eckman, John;  Bergsten, Julie;  Tucker, Kelinda;  Zach, Leigh Anne;  Karlan, Beth Y.;  Lester, Jenny;  Orsulic, Sandra;  Sun, Qiang;  Naresh, Rashi;  Pihl, Todd;  Wan, Yunhu;  Zaren, Howard;  Sapp, Jennifer;  Miller, Judy;  Drwiega, Paul;  Ojesina, Akinyemi I.;  Murray, Bradley A.;  Zhang, Hailei;  Cherniack, Andrew D.;  Sougnez, Carrie;  Pedamallu, Chandra Sekhar;  Lichtenstein, Lee;  Meyerson, Matthew;  Noble, Michael S.;  Heiman, David I.;  Voet, Doug;  Getz, Gad;  Saksena, Gordon;  Kim, Jaegil;  Shih, Juliann;  Cho, Juok;  Lawrence, Michael S.;  Gehlenborg, Nils;  Lin, Pei;  Beroukhim, Rameen;  Frazer, Scott;  Gabriel, Stacey B.;  Schumacher, Steven E.;  Leraas, Kristen M.;  Lichtenberg, Tara M.;  Zmuda, Erik;  Bowen, Jay;  Frick, Jessica;  Gastier-Foster, Julie M.;  Wise, Lisa;  Gerken, Mark;  Ramirez, Nilsa C.;  Danilova, Ludmila;  Cope, Leslie;  Baylin, Stephen B.;  Salvesen, Helga B.;  Vellano, Christopher P.;  Ju, Zhenlin;  Diao, Lixia;  Zhao, Hao;  Chong, Zechen;  Ryan, Michael C.;  Martinez-Ledesma, Emmanuel;  Verhaak, Roeland G.;  Byers, Lauren Averett;  Yuan, Yuan;  Chen, Ken;  Ling, Shiyun;  Mills, Gordon B.;  Lu, Yiling;  Akbani, Rehan;  Seth, Sahil;  Liang, Han;  Wang, Jing;  Han, Leng;  Weinstein, John N.;  Bristow, Christopher A.;  Zhang, Wei;  Mahadeshwar, Harshad S.;  Sun, Huandong;  Tang, Jiabin;  Zhang, Jianhua;  Song, Xingzhi;  Protopopov, Alexei;  Shaw, Kenna R. Mills;  Chin, Lynda;  Olabode, Oluwole;  Ojesina, Akinyemi I.;  DiSaia, Philip;  Radenbaugh, Amie;  Haussler, David;  Zhu, Jingchun;  Stuart, Josh;  Chalise, Prabhakar;  Koestler, Devin;  Fridley, Brooke L.;  Godwin, Andrew K.;  Madan, Rashna;  Ciriello, Giovanni;  Martinez, Cathleen;  Higgins, Kelly;  Bocklage, Therese;  Auman, J. Todd;  Perou, Charles M.;  Tan, Donghui;  Parker, Joel S.;  Hoadley, Katherine A.;  Wilkerson, Matthew D.;  Mieczkowski, Piotr A.;  Skelly, Tara;  Veluvolu, Umadevi;  Hayes, D. Neil;  Rathmell, W. Kimryn;  Hoyle, Alan P.;  Simons, Janae V.;  Wu, Junyuan;  Mose, Lisle E.;  Soloway, Matthew G.;  Balu, Saianand;  Meng, Shaowu;  Jefferys, Stuart R.;  Bodenheimer, Tom;  Shi, Yan;  Roach, Jeffrey;  Thorne, Leigh B.;  Boice, Lori;  Huang, Mei;  Jones, Corbin D.;  Zuna, Rosemary;  Walker, Joan;  Gunderson, Camille;  Snowbarger, Carie;  Brown, David;  Moxley, Katherine;  Moore, Kathleen;  Andrade, Kelsi;  Landrum, Lisa;  Mannel, Robert;  McMeekin, Scott;  Johnson, Starla;  Nelson, Tina;  Elishaev, Esther;  Dhir, Rajiv;  Edwards, Robert;  Bhargava, Rohit;  Tiezzi, Daniel G.;  Andrade, Jurandyr M.;  Noushmehr, Houtan;  Carlotti, Carlos Gilberto, Jr.;  Tirapelli, Daniela Pretti da Cunha;  Weisenberger, Daniel J.;  Van Den Berg, David J.;  Maglinte, Dennis T.;  Bootwalla, Moiz S.;  Lai, Phillip H.;  Triche, Timothy, Jr.;  Swisher, Elizabeth M.;  Agnew, Kathy J.;  Shelley, Carl Simon;  Laird, Peter W.;  Schwarz, Julie;  Grigsby, Perry;  Mutch, David
收藏  |  浏览/下载：14/0  |  提交时间：2019/04/09