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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 期刊论文
Science, 2021
作者:  Nir Drayman;  Jennifer K. DeMarco;  Krysten A. Jones;  Saara-Anne Azizi;  Heather M. Froggatt;  Kemin Tan;  Natalia Ivanovna Maltseva;  Siquan Chen;  Vlad Nicolaescu;  Steve Dvorkin;  Kevin Furlong;  Rahul S. Kathayat;  Mason R. Firpo;  Vincent Mastrodomenico;  Emily A. Bruce;  Madaline M. Schmidt;  Robert Jedrzejczak;  Miguel Á. Muñoz-Alía;  Brooke Schuster;  Vishnu Nair;  Kyu-yeon Han;  Amornrat O’Brien;  Anastasia Tomatsidou;  Bjoern Meyer;  Marco Vignuzzi;  Dominique Missiakas;  Jason W. Botten;  Christopher B. Brooke;  Hyun Lee;  Susan C. Baker;  Bryan C. Mounce;  Nicholas S. Heaton;  William E. Severson;  Kenneth E. Palmer;  Bryan C. Dickinson;  Andrzej Joachimiak;  Glenn Randall;  Savaş Tay
收藏  |  浏览/下载：13/0  |  提交时间：2021/08/25
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 期刊论文
Science, 2021
作者:  Tia A. Tummino;  Veronica V. Rezelj;  Benoit Fischer;  Audrey Fischer;  Matthew J. O’Meara;  Blandine Monel;  Thomas Vallet;  Kris M. White;  Ziyang Zhang;  Assaf Alon;  Heiko Schadt;  Henry R. O’Donnell;  Jiankun Lyu;  Romel Rosales;  Briana L. McGovern;  Raveen Rathnasinghe;  Sonia Jangra;  Michael Schotsaert;  Jean-René Galarneau;  Nevan J. Krogan;  Laszlo Urban;  Kevan M. Shokat;  Andrew C. Kruse;  Adolfo García-Sastre;  Olivier Schwartz;  Francesca Moretti;  Marco Vignuzzi;  Francois Pognan;  Brian K. Shoichet
收藏  |  浏览/下载：25/0  |  提交时间：2021/08/10
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A 期刊论文
Science, 2021
作者:  Kris M. White;  Romel Rosales;  Soner Yildiz;  Thomas Kehrer;  Lisa Miorin;  Elena Moreno;  Sonia Jangra;  Melissa B. Uccellini;  Raveen Rathnasinghe;  Lynda Coughlan;  Carles Martinez-Romero;  Jyoti Batra;  Ajda Rojc;  Mehdi Bouhaddou;  Jacqueline M. Fabius;  Kirsten Obernier;  Marion Dejosez;  María José Guillén;  Alejandro Losada;  Pablo Avilés;  Michael Schotsaert;  Thomas Zwaka;  Marco Vignuzzi;  Kevan M. Shokat;  Nevan J. Krogan;  Adolfo García-Sastre
收藏  |  浏览/下载：13/0  |  提交时间：2021/03/02