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HACKS TO HELP RESEARCHERS PUT WORDS ON THE PAGE 期刊论文
NATURE, 2020, 580 (7801) : 151-153
作者:  Lee, Jiyoon;  Rabbani, Cyrus C.;  Gao, Hongyu;  Steinhart, Matthew R.;  Woodruff, Benjamin M.;  Pflum, Zachary E.;  Kim, Alexander;  Heller, Stefan;  Liu, Yunlong;  Shipchandler, Taha Z.;  Koehler, Karl R.
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/03

Productivity coaches, boot camps and online meet-ups teach researchers to avoid distractions and negative thoughts to get their writing projects done.


Productivity coaches, boot camps and online meet-ups teach researchers to avoid distractions and negative thoughts to get their writing projects done.


  
Reform retractions to make them more transparent 期刊论文
NATURE, 2020, 582 (7811) : 149-149
作者:  Viglione, Giuliana
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/03
Entanglement-based secure quantum cryptography over 1,120 kilometres 期刊论文
NATURE, 2020
作者:  Paldi, Flora;  Alver, Bonnie;  Robertson, Daniel;  Schalbetter, Stephanie A.;  Kerr, Alastair;  Kelly, David A.;  Baxter, Jonathan;  Neale, Matthew J.;  Marston, Adele L.
收藏  |  浏览/下载:48/0  |  提交时间:2020/07/03

An efficient entanglement-based quantum key distribution is sent from the Micius satellite to two ground observatories 1,120 kilometres apart to establish secure quantum cryptography for the exchange ofquantum keys.


Quantum key distribution (QKD)(1-3)is a theoretically secure way of sharing secret keys between remote users. It has been demonstrated in a laboratory over a coiled optical fibre up to 404 kilometres long(4-7). In the field, point-to-point QKD has been achieved from a satellite to a ground station up to 1,200 kilometres away(8-10). However, real-world QKD-based cryptography targets physically separated users on the Earth, for which the maximum distance has been about 100 kilometres(11,12). The use of trusted relays can extend these distances from across a typical metropolitan area(13-16)to intercity(17)and even intercontinental distances(18). However, relays pose security risks, which can be avoided by using entanglement-based QKD, which has inherent source-independent security(19,20). Long-distance entanglement distribution can be realized using quantum repeaters(21), but the related technology is still immature for practical implementations(22). The obvious alternative for extending the range of quantum communication without compromising its security is satellite-based QKD, but so far satellite-based entanglement distribution has not been efficient(23)enough to support QKD. Here we demonstrate entanglement-based QKD between two ground stations separated by 1,120 kilometres at a finite secret-key rate of 0.12 bits per second, without the need for trusted relays. Entangled photon pairs were distributed via two bidirectional downlinks from the Micius satellite to two ground observatories in Delingha and Nanshan in China. The development of a high-efficiency telescope and follow-up optics crucially improved the link efficiency. The generated keys are secure for realistic devices, because our ground receivers were carefully designed to guarantee fair sampling and immunity to all known side channels(24,25). Our method not only increases the secure distance on the ground tenfold but also increases the practical security of QKD to an unprecedented level.


  
Bioluminescent backlighting illuminates the complex visual signals of a social squid in the deep sea 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (15) : 8524-8531
作者:  Burford, Benjamin P.;  Robison, Bruce H.
收藏  |  浏览/下载:5/0  |  提交时间:2020/05/13
behavioral ecology  social evolution  deep-sea biology  visual signaling  
Coping with COVID-19 期刊论文
NATURE GEOSCIENCE, 2020, 13 (4) : 257-257
作者:  [unavailable]
收藏  |  浏览/下载:20/0  |  提交时间:2020/08/18
Olfactory sniffing signals consciousness in unresponsive patients with brain injuries 期刊论文
NATURE, 2020
作者:  Hellmuth, Susanne;  Gomez-H, Laura;  Pendas, Alberto M.;  Stemmann, Olaf
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

After severe brain injury, it can be difficult to determine the state of consciousness of a patient, to determine whether the patient is unresponsive or perhaps minimally conscious(1), and to predict whether they will recover. These diagnoses and prognoses are crucial, as they determine therapeutic strategies such as pain management, and can underlie end-of-life decisions(2,3). Nevertheless, there is an error rate of up to 40% in determining the state of consciousness in patients with brain injuries(4,5). Olfaction relies on brain structures that are involved in the basic mechanisms of arousal(6), and we therefore hypothesized that it may serve as a biomarker for consciousness(7). Here we use a non-verbal non-task-dependent measure known as the sniff response(8-11) to determine consciousness in patients with brain injuries. By measuring odorant-dependent sniffing, we gain a sensitive measure of olfactory function(10-15). We measured the sniff response repeatedly over time in patients with severe brain injuries and found that sniff responses significantly discriminated between unresponsive and minimally conscious states at the group level. Notably, at the single-patient level, if an unresponsive patient had a sniff response, this assured future regaining of consciousness. In addition, olfactory sniff responses were associated with long-term survival rates. These results highlight the importance of olfaction in human brain function, and provide an accessible tool that signals consciousness and recovery in patients with brain injuries.


Odorant-dependent sniff responses predicted the long-term survival rates of patients with severe brain injury, and discriminated between individuals who were unresponsive and in minimally conscious states.


  
FIGHT CORONAVIRUS MISINFORMATION 期刊论文
NATURE, 2020, 581 (7808) : 345-346
作者:  Mallapaty, Smriti
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/03

Scientists have a responsibility to communicate effectively and compassionately, says Samantha Yammine. Here'  s how.


Scientists have a responsibility to communicate effectively and compassionately, says Samantha Yammine. Here'  s how.


  
Pharmacologic fibroblast reprogramming into photoreceptors restores vision 期刊论文
NATURE, 2020, 581 (7806) : 83-+
作者:  Jiang, Mingkai;  Medlyn, Belinda E.;  Drake, John E.;  Duursma, Remko A.;  Anderson, Ian C.;  Barton, Craig V. M.;  Boer, Matthias M.;  Carrillo, Yolima;  Castaneda-Gomez, Laura;  Collins, Luke;  Crous, Kristine Y.;  De Kauwe, Martin G.;  dos Santos, Bruna M.;  Emmerson, Kathryn M.;  Facey, Sarah L.;  Gherlenda, Andrew N.;  Gimeno, Teresa E.;  Hasegawa, Shun;  Johnson, Scott N.;  Kannaste, Astrid;  Macdonald, Catriona A.;  Mahmud, Kashif;  Moore, Ben D.;  Nazaries, Loic;  Neilson, Elizabeth H. J.;  Nielsen, Uffe N.;  Niinemets, Ulo;  Noh, Nam Jin;  Ochoa-Hueso, Raul;  Pathare, Varsha S.;  Pendall, Elise;  Pihlblad, Johanna;  Pineiro, Juan;  Powell, Jeff R.;  Power, Sally A.;  Reich, Peter B.;  Renchon, Alexandre A.;  Riegler, Markus;  Rinnan, Riikka;  Rymer, Paul D.;  Salomon, Roberto L.;  Singh, Brajesh K.;  Smith, Benjamin;  Tjoelker, Mark G.;  Walker, Jennifer K. M.;  Wujeska-Klause, Agnieszka;  Yang, Jinyan;  Zaehle, Soenke;  Ellsworth, David S.
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/03

Photoreceptor loss is the final common endpoint in most retinopathies that lead to irreversible blindness, and there are no effective treatments to restore vision(1,2). Chemical reprogramming of fibroblasts offers an opportunity to reverse vision loss  however, the generation of sensory neuronal subtypes such as photoreceptors remains a challenge. Here we report that the administration of a set of five small molecules can chemically induce the transformation of fibroblasts into rod photoreceptor-like cells. The transplantation of these chemically induced photoreceptor-like cells (CiPCs) into the subretinal space of rod degeneration mice (homozygous for rd1, also known as Pde6b) leads to partial restoration of the pupil reflex and visual function. We show that mitonuclear communication is a key determining factor for the reprogramming of fibroblasts into CiPCs. Specifically, treatment with these five compounds leads to the translocation of AXIN2 to the mitochondria, which results in the production of reactive oxygen species, the activation of NF-kappa B and the upregulation of Ascl1. We anticipate that CiPCs could have therapeutic potential for restoring vision.


A set of five small molecules can induce the transformation of fibroblasts into rod photoreceptor-like cells, which can partially restore pupil reflex and visual function when transplanted into a rod degeneration mouse model.


  
GRAPHIC CONTENT: PICTURING SCIENCE 期刊论文
NATURE, 2020, 582 (7810) : 137-138
作者:  Crew, Bec
收藏  |  浏览/下载:0/0  |  提交时间:2020/07/03
Urban Near-Surface Seismic Monitoring Using Distributed Acoustic Sensing 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (6)
作者:  Fang, Gang;  Li, Yunyue Elita;  Zhao, Yumin;  Martin, Eileen R.
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/02
distributed acoustic sensing  urban seismology  near surface  passive seismic  seismic monitoring