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Recycling and metabolic flexibility dictate life in the lower oceanic crust 期刊论文
NATURE, 2020, 579 (7798) : 250-+
作者:  Zhou, Peng;  Yang, Xing-Lou;  Wang, Xian-Guang;  Hu, Ben;  Zhang, Lei;  Zhang, Wei;  Si, Hao-Rui;  Zhu, Yan;  Li, Bei;  Huang, Chao-Lin;  Chen, Hui-Dong;  Chen, Jing;  Luo, Yun;  Guo, Hua;  Jiang, Ren-Di;  Liu, Mei-Qin;  Chen, Ying;  Shen, Xu-Rui;  Wang, Xi;  Zheng, Xiao-Shuang;  Zhao, Kai;  Chen, Quan-Jiao;  Deng, Fei;  Liu, Lin-Lin;  Yan, Bing;  Zhan, Fa-Xian;  Wang, Yan-Yi;  Xiao, Geng-Fu;  Shi, Zheng-Li
收藏  |  浏览/下载：37/0  |  提交时间：2020/05/13

The lithified lower oceanic crust is one of Earth'  s last biological frontiers as it is difficult to access. It is challenging for microbiota that live in marine subsurface sediments or igneous basement to obtain sufficient carbon resources and energy to support growth(1-3) or to meet basal power requirements(4) during periods of resource scarcity. Here we show how limited and unpredictable sources of carbon and energy dictate survival strategies used by low-biomass microbial communities that live 10-750 m below the seafloor at Atlantis Bank, Indian Ocean, where Earth'  s lower crust is exposed at the seafloor. Assays of enzyme activities, lipid biomarkers, marker genes and microscopy indicate heterogeneously distributed and viable biomass with ultralow cell densities (fewer than 2,000 cells per cm(3)). Expression of genes involved in unexpected heterotrophic processes includes those with a role in the degradation of polyaromatic hydrocarbons, use of polyhydroxyalkanoates as carbon-storage molecules and recycling of amino acids to produce compounds that can participate in redox reactions and energy production. Our study provides insights into how microorganisms in the plutonic crust are able to survive within fractures or porous substrates by coupling sources of energy to organic and inorganic carbon resources that are probably delivered through the circulation of subseafloor fluids or seawater.


  
Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Huang, Fengjie;  Zheng, Xiaojiao;  Ma, Xiaohui;  Jiang, Runqiu;  Zhou, Wangyi;  Zhou, Shuiping;  Zhang, Yunjing;  Lei, Sha;  Wang, Shouli;  Kuang, Junliang;  Han, Xiaolong;  Wei, Meilin;  You, Yijun;  Li, Mengci;  Li, Yitao;  Liang, Dandan;  Liu, Jiajian;  Chen, Tianlu;  Yan, Chao;  Wei, Runmin;  Rajani, Cynthia;  Shen, Chengxing;  Xie, Guoxiang;  Bian, Zhaoxiang;  Li, Houkai;  Zhao, Aihua;  Jia, Wei
收藏  |  浏览/下载：16/0  |  提交时间：2019/11/27
Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Jiang, Xi;  Hu, Chao;  Ferchen, Kyle;  Nie, Ji;  Cui, Xiaolong;  Chen, Chih-Hong;  Cheng, Liting;  Zuo, Zhixiang;  Seibel, William;  He, Chunjiang;  Tang, Yixuan;  Skibbe, Jennifer R.;  Wunderlich, Mark;  Reinhold, William C.;  Dong, Lei;  Shen, Chao;  Arnovitz, Stephen;  Ulrich, Bryan;  Lu, Jiuwei;  Weng, Hengyou;  Su, Rui;  Huang, Huilin;  Wang, Yungui;  Li, Chenying;  Qin, Xi;  Mulloy, James;  Zheng, Yi;  Diao, Jiajie;  Jin, Jie;  Li, Chong;  Liu, Paul P.;  He, Chuan;  Chen, Yuan;  Chen, Jianjun
收藏  |  浏览/下载：17/0  |  提交时间：2019/11/27
Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Li, Shang-Ze;  Shu, Qi-Peng;  Song, Yang;  Zhang, Hui-Hui;  Liu, Yi;  Jin, Bing-Xue;  Liuyu, Tian-Zi;  Li, Chao;  Huang, Xi-Chen;  Du, Run-Lei;  Song, Wei;  Zhong, Bo;  Zhang, Xiao-Dong
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/27
Room-temperature chiral charge pumping in Dirac semimetals 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Zhang, Cheng;  Zhang, Enze;  Wang, Weiyi;  Liu, Yanwen;  Chen, Zhi-Gang;  Lu, Shiheng;  Liang, Sihang;  Cao, Junzhi;  Yuan, Xiang;  Tang, Lei;  Li, Qian;  Zhou, Chao;  Gu, Teng;  Wu, Yizheng;  Zou, Jin;  Xiu, Faxian
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
Tunable intrinsic strain in two-dimensional transition metal electrocatalysts 期刊论文
SCIENCE, 2019, 363 (6429) : 870-+
作者:  Wang, Lei;  Zeng, Zhenhua;  Gao, Wenpei;  Maxson, Tristan;  Raciti, David;  Giroux, Michael;  Pan, Xiaoqing;  Wang, Chao;  Greeley, Jeffrey
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/27
TGF-beta signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Lyu, Guoliang;  Guan, Yiting;  Zhang, Chao;  Zong, Le;  Sun, Lei;  Huang, Xiaoke;  Huang, Li;  Zhang, Lijun;  Tian, Xiao-Li;  Zhou, Zhongjun;  Tao, Wei
收藏  |  浏览/下载：6/0  |  提交时间：2019/11/27
Atmospheric new particle formation from sulfuric acid and amines in a Chinese megacity 期刊论文
SCIENCE, 2018, 361 (6399) : 278-+
作者:  Yao, Lei;  Garmash, Olga;  Bianchi, Federico;  Zheng, Jun;  Yan, Chao;  Kontkanen, Jenni;  Junninen, Heikki;  Mazon, Stephany Buenrostro;  Ehn, Mikael;  Paasonen, Pauli;  Sipila, Mikko;  Wang, Mingyi;  Wang, Xinke;  Xiao, Shan;  Chen, Hangfei;  Lu, Yiqun;  Zhang, Bowen;  Wang, Dongfang;  Fu, Qingyan;  Geng, Fuhai;  Li, Li;  Wang, Hongli;  Qiao, Liping;  Yang, Xin;  Chen, Jianmin;  Kerminen, Veli-Matti;  Petaja, Tuukka;  Worsnop, Douglas R.;  Kulmala, Markku;  Wang, Lin
收藏  |  浏览/下载：12/0  |  提交时间：2019/11/27
Response to Comment on "Synthesis and characterization of the pentazolate anion cyclo-N-5(-) in (N-5)(6)(H3O)(3)(NH4)(4)Cl" 期刊论文
SCIENCE, 2018, 359 (6381)
作者:  Jiang, Chao;  Zhang, Lei;  Sun, Chengguo;  Zhang, Chong;  Yang, Chen;  Chen, Jun;  Hu, Bingcheng
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
Ground-to-satellite quantum teleportation 期刊论文
NATURE, 2017, 549 (7670) : 70-+
作者:  Ren, Ji-Gang;  Xu, Ping;  Yong, Hai-Lin;  Zhang, Liang;  Liao, Sheng-Kai;  Yin, Juan;  Liu, Wei-Yue;  Cai, Wen-Qi;  Yang, Meng;  Li, Li;  Yang, Kui-Xing;  Han, Xuan;  Yao, Yong-Qiang;  Li, Ji;  Wu, Hai-Yan;  Wan, Song;  Liu, Lei;  Liu, Ding-Quan;  Kuang, Yao-Wu;  He, Zhi-Ping;  Shang, Peng;  Guo, Cheng;  Zheng, Ru-Hua;  Tian, Kai;  Zhu, Zhen-Cai;  Liu, Nai-Le;  Lu, Chao-Yang;  Shu, Rong;  Chen, Yu-Ao;  Peng, Cheng-Zhi;  Wang, Jian-Yu;  Pan, Jian-Wei
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/27