Global S&T Development Trend Analysis Platform of Resources and Environment
Toll-like receptors can initiate an immune response when they detect signs of a viral or microbial threat. New insight into how such receptor activation drives defence programs should aid our efforts to understand autoimmune diseases.
Key adaptor protein found in a pathway that drives interferon production.
A zinc-sensing ion channel, Hodor, has now been found in the intestine of fruit flies. Hodor activates the TORC1 signalling pathway, and in doing so, influences organism-wide growth and metabolism.
Cellular stress can result in dysfunction and disease, and mechanisms exist to combat this. Previously unknown steps have been uncovered in a pathway that signals when mitochondrial organelles are dysfunctional.
