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Carbonyl compounds in the atmosphere: A review of abundance, source and their contributions to O3 and SOA formation 期刊论文
Atmospheric Research, 2022
作者:  Qian Liu, Yuan Gao, Weiwen Huang, Zhenhao Ling, ... Xuemei Wang
收藏  |  浏览/下载:18/0  |  提交时间:2022/04/15
European Carbon Uptake has not Benefited from Vegetation Greening 期刊论文
Geophysical Research Letters, 2021
作者:  Xuebang Liu;  Bin He;  Lanlan Guo;  Ling Huang;  Wenping Yuan;  Xiuzhi Chen;  Xingming Hao;  Xiaoming Xie;  Yafeng Zhang;  Ziqian Zhong;  Tiewei Li;  Aifang Chen
收藏  |  浏览/下载:15/0  |  提交时间:2021/10/07
A van der Waals interface that creates in-plane polarization and a spontaneous photovoltaic effect 期刊论文
Science, 2021
作者:  Takatoshi Akamatsu;  Toshiya Ideue;  Ling Zhou;  Yu Dong;  Sota Kitamura;  Mao Yoshii;  Dongyang Yang;  Masaru Onga;  Yuji Nakagawa;  Kenji Watanabe;  Takashi Taniguchi;  Joseph Laurienzo;  Junwei Huang;  Ziliang Ye;  Takahiro Morimoto;  Hongtao Yuan;  Yoshihiro Iwasa
收藏  |  浏览/下载:14/0  |  提交时间:2021/04/06
Meltwater‐driven water‐level fluctuations of Bosten Lake in arid China over the past 2,000 years 期刊论文
Geophysical Research Letters, 2020
作者:  Yuan Li;  Ling Hu;  Yongtao Zhao;  Haipeng Wang;  Xiaozhong Huang;  Guangjie Chen;  Jaakko Johannes Leppä;  nen;  Luciane Fontana;  Lele Ren;  Zhilin Shi;  Bing Liu;  Hui Zhao
收藏  |  浏览/下载:12/0  |  提交时间:2020/12/07
Why is the Terrestrial Water Storage in Dryland Regions Declining? A Perspective based on GRACE Satellite Observations and Noah‐MP Model Simulations 期刊论文
Water Resources Research, 2020
作者:  Li‐;  Ling Chang;  Ruiqiang Yuan;  Hoshin V. Gupta;  C. L. Winter;  Guo‐;  Yue Niu
收藏  |  浏览/下载:14/0  |  提交时间:2020/11/09
Effect of allelopathy on plant performance: a meta‐analysis 期刊论文
Ecology Letters, 2020
作者:  Zhijie Zhang;  Yanjie Liu;  Ling Yuan;  Ewald Weber;  Mark van Kleunen
收藏  |  浏览/下载:7/0  |  提交时间:2020/10/26
Structure and mechanism of human diacylglycerol O-acyltransferase 1 期刊论文
NATURE, 2020, 581 (7808) : 329-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/03

The structure of human diacylglycerol O-acyltransferase 1, a membrane protein that synthesizes triacylglycerides, is solved with cryo-electron microscopy, providing insight into its function and mechanism of enzymatic activity.


Diacylglycerol O-acyltransferase 1 (DGAT1) synthesizes triacylglycerides and is required for dietary fat absorption and fat storage in humans(1). DGAT1 belongs to the membrane-bound O-acyltransferase (MBOAT) superfamily, members of which are found in all kingdoms of life and are involved in the acylation of lipids and proteins(2,3). How human DGAT1 and other mammalian members of the MBOAT family recognize their substrates and catalyse their reactions is unknown. The absence of three-dimensional structures also hampers rational targeting of DGAT1 for therapeutic purposes. Here we present the cryo-electron microscopy structure of human DGAT1 in complex with an oleoyl-CoA substrate. Each DGAT1 protomer has nine transmembrane helices, eight of which form a conserved structural fold that we name the MBOAT fold. The MBOAT fold in DGAT1 forms a hollow chamber in the membrane that encloses highly conserved catalytic residues. The chamber has separate entrances for each of the two substrates, fatty acyl-CoA and diacylglycerol. DGAT1 can exist as either a homodimer or a homotetramer and the two forms have similar enzymatic activity. The N terminus of DGAT1 interacts with the neighbouring protomer and these interactions are required for enzymatic activity.


  
The online competition between pro- and anti-vaccination views 期刊论文
NATURE, 2020, 582 (7811) : 230-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

Insights into the interactions between pro- and anti-vaccination clusters on Facebook can enable policies and approaches that attempt to interrupt the shift to anti-vaccination views and persuade undecided individuals to adopt a pro-vaccination stance.


Distrust in scientific expertise(1-14) is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks(2-4), as happened for measles in 2019(5,6). Homemade remedies(7,8) and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice(9-11). There is a lack of understanding about how this distrust evolves at the system level(13,14). Here we provide a map of the contention surrounding vaccines that has emerged from the global pool of around three billion Facebook users. Its core reveals a multi-sided landscape of unprecedented intricacy that involves nearly 100 million individuals partitioned into highly dynamic, interconnected clusters across cities, countries, continents and languages. Although smaller in overall size, anti-vaccination clusters manage to become highly entangled with undecided clusters in the main online network, whereas pro-vaccination clusters are more peripheral. Our theoretical framework reproduces the recent explosive growth in anti-vaccination views, and predicts that these views will dominate in a decade. Insights provided by this framework can inform new policies and approaches to interrupt this shift to negative views. Our results challenge the conventional thinking about undecided individuals in issues of contention surrounding health, shed light on other issues of contention such as climate change(11), and highlight the key role of network cluster dynamics in multi-species ecologies(15).


  
CO2 mineralization and utilization by alkaline solid wastes for potential carbon reduction 期刊论文
NATURE SUSTAINABILITY, 2020, 3 (5) : 399-405
作者:  Pan, Shu-Yuan;  Chen, Yi-Hung;  Fan, Liang-Shih;  Kim, Hyunook;  Gao, Xiang;  Ling, Tung-Chai;  Chiang, Pen-Chi;  Pei, Si-Lu;  Gu, Guowei
收藏  |  浏览/下载:11/0  |  提交时间:2020/05/13
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Qiu, Fang;  Tang, Ruqi;  Zuo, Xianbo;  Shi, Xingjuan;  Wei, Yiran;  Zheng, Xiaodong;  Dai, Yaping;  Gong, Yuhua;  Wang, Lan;  Xu, Ping;  Zhu, Xiang;  Wu, Jian;  Han, Chongxu;  Gao, Yueqiu;  Zhang, Kui;  Jiang, Yuzhang;  Zhou, Jianbo;  Shao, Youlin;  Hu, Zhigang;  Tian, Ye;  Zhang, Haiyan;  Dai, Na;  Liu, Lei;  Wu, Xudong;  Zhao, Weifeng;  Zhang, Xiaomin;  Zang, Zhidong;  Nie, Jinshan;  Sun, Weihao;  Zhao, Yi;  Mao, Yuan;  Jiang, Po;  Ji, Hualiang;  Dong, Qing;  Li, Junming;  Li, Zhenzhong;  Bai, Xinli;  Li, Li;  Lin, Maosong;  Dong, Ming;  Li, Jinxin;  Zhu, Ping;  Wang, Chan;  Zhang, Yanqiu;  Jiang, Peng;  Wang, Yujue;  Jawed, Rohil;  Xu, Jing;  Zhang, Yu;  Wang, Qixia;  Yang, Yue;  Yang, Fan;  Lian, Min;  Jiang, Xiang;  Xiao, Xiao;  Li, Yanmei;  Fang, Jingyuan;  Qiu, Dekai;  Zhu, Zhen;  Qiu, Hong;  Zhang, Jianqiong;  Tian, Wenyan;  Chen, Sufang;  Jiang, Ling;  Ji, Bing;  Li, Ping;  Chen, Guochang;  Wu, Tianxue;  Sun, Yan;  Yu, Jianjiang;  Tang, Huijun;  He, Michun;  Xia, Min;  Pei, Hao;  Huang, Lihua;  Qing, Zhuye;  Wu, Jianfang;  Huang, Qinghai;  Han, Junhai;  Xie, Wei;  Sun, Zhongsheng;  Guo, Jian;  He, Gengsheng;  Gershwin, M. Eric;  Lian, Zhexiong;  Liu, Xiang;  Seldin, Michael F.;  Liu, Xiangdong;  Chen, Weichang;  Ma, Xiong
收藏  |  浏览/下载:17/0  |  提交时间:2019/11/27