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Using DNA to reunify separated migrant families 期刊论文
Science, 2021
作者:  Elizabeth Barnert;  Sara H. Katsanis;  Ranit Mishori;  Jennifer K. Wagner;  Richard F. Selden;  Diana Madden;  Dan Berger;  Henry Erlich;  Kathryn Hampton;  Andreas Kleiser;  Alessandra La Vaccara;  Thomas J. Parsons;  Fredy A. Peccerelli;  Mariana Herrera Piñero;  Michael J. Stebbins;  Patricia Vásquez;  Curren W. Warf;  Thomas J. White;  Eric Stover;  M. Veronica Svetaz
收藏  |  浏览/下载：16/0  |  提交时间：2021/06/15
Predation landscapes influence migratory prey ecology and evolution 期刊论文
Trends in Ecology & Evolution\, 2021
作者:  Megan C. Sabal:Mark S. Boyce:Corie L. Charpentier:Nathan B. Furey:Thomas M. Luhring:Hans W. Martin:Michael C. Melnychuk:Robert B. Srygley:C. Michael Wagner:Aaron J. Wirsing:Ronald C. Ydenberg:Eric P. Palkovacs
收藏  |  浏览/下载：10/0  |  提交时间：2021/05/21
Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes 期刊论文
Science, 2021
作者:  Chadi M. Saad-Roy;  Sinead E. Morris;  C. Jessica E. Metcalf;  Michael J. Mina;  Rachel E. Baker;  Jeremy Farrar;  Edward C. Holmes;  Oliver G. Pybus;  Andrea L. Graham;  Simon A. Levin;  Bryan T. Grenfell;  Caroline E. Wagner
收藏  |  浏览/下载：11/0  |  提交时间：2021/04/29
Partial immunity and SARS-CoV-2 mutations—Response 期刊论文
Science, 2021
作者:  Chadi M. Saad-Roy;  Sinead E. Morris;  C. Jessica E. Metcalf;  Michael J. Mina;  Rachel E. Baker;  Jeremy Farrar;  Edward C. Holmes;  Oliver G. Pybus;  Andrea L. Graham;  Simon A. Levin;  Bryan T. Grenfell;  Caroline E. Wagner
收藏  |  浏览/下载：10/0  |  提交时间：2021/04/29
Immune life history, vaccination, and the dynamics of SARS-CoV-2 over the next 5 years 期刊论文
Science, 2020
作者:  Chadi M. Saad-Roy;  Caroline E. Wagner;  Rachel E. Baker;  Sinead E. Morris;  Jeremy Farrar;  Andrea L. Graham;  Simon A. Levin;  Michael J. Mina;  C. Jessica E. Metcalf;  Bryan T. Grenfell
收藏  |  浏览/下载：10/0  |  提交时间：2020/11/20
Trajectories to High Income: Growth Dynamics in Japan, the People’s Republic of China, and the Republic of Korea 科技报告
来源：Asian Development Bank. 出版年： 2020
作者:  Michael Murach;  Helmut Wagner;  Jungsuk Kim
收藏  |  浏览/下载：10/0  |  提交时间：2020/10/12
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease 期刊论文
NATURE, 2020, 577 (7790) : 399-+
作者:  Gate, David;  Saligrama, Naresha;  Leventhal, Olivia;  Yang, Andrew C.;  Unger, Michael S.;  Middeldorp, Jinte;  Chen, Kelly;  Lehallier, Benoit;  Channappa, Divya;  De Los Santos, Mark B.;  McBride, Alisha;  Pluvinage, John;  Elahi, Fanny;  Tam, Grace Kyin-Ye;  Kim, Yongha;  Greicius, Michael;  Wagner, Anthony D.;  Aigner, Ludwig;  Galasko, Douglas R.;  Davis, Mark M.;  Wyss-Coray, Tony
收藏  |  浏览/下载：6/0  |  提交时间：2020/07/03

Alzheimer'  s disease is an incurable neurodegenerative disorder in which neuroinflammation has a critical function(1). However, little is known about the contribution of the adaptive immune response in Alzheimer'  s disease(2). Here, using integrated analyses of multiple cohorts, we identify peripheral and central adaptive immune changes in Alzheimer'  s disease. First, we performed mass cytometry of peripheral blood mononuclear cells and discovered an immune signature of Alzheimer'  s disease that consists of increased numbers of CD8(+) T effector memory CD45RA(+) (T-EMRA) cells. In a second cohort, we found that CD8(+) T-EMRA cells were negatively associated with cognition. Furthermore, single-cell RNA sequencing revealed that T cell receptor (TCR) signalling was enhanced in these cells. Notably, by using several strategies of single-cell TCR sequencing in a third cohort, we discovered clonally expanded CD8(+) T-EMRA cells in the cerebrospinal fluid of patients with Alzheimer'  s disease. Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with Alzheimer'  s disease to two separate Epstein-Barr virus antigens. These results reveal an adaptive immune response in the blood and cerebrospinal fluid in Alzheimer'  s disease and provide evidence of clonal, antigen-experienced T cells patrolling the intrathecal space of brains affected by age-related neurodegeneration.


  
Solid Ammonium Nitrate Aerosols as Efficient Ice Nucleating Particles at Cirrus Temperatures 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2020, 125 (8)
作者:  Wagner, Robert;  Bertozzi, Barbara;  Hoepfner, Michael;  Hoehler, Kristina;  Moehler, Ottmar;  Saathoff, Harald;  Leisner, Thomas
收藏  |  浏览/下载：9/0  |  提交时间：2020/07/02
Charting two centuries of transformation in a coastal social-ecological system: A mixed methods approach 期刊论文
GLOBAL ENVIRONMENTAL CHANGE-HUMAN AND POLICY DIMENSIONS, 2020, 61
作者:  Thurstan, Ruth H.;  Diggles, Ben K.;  Gillies, Chris L.;  Strong, Michael K.;  Kerkhove, Ray;  Buckley, Sarah M.;  King, Robert A.;  Smythe, Vince;  Heller-Wagner, Gideon;  Weeks, Rebecca;  Palin, Fred;  McLeod, Ian
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/02
Cultural history  Environmental history  Historical ecology  Moreton Bay  Oyster  Shifting baseline syndrome  
Single cell analyses reveal contrasting life strategies of the two main nitrifiers in the ocean 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Kitzinger, Katharina;  Marchant, Hannah K.;  Bristow, Laura A.;  Herbold, Craig W.;  Padilla, Cory C.;  Kidane, Abiel T.;  Littmann, Sten;  Daims, Holger;  Pjevac, Petra;  Stewart, Frank J.;  Wagner, Michael;  Kuypers, Marcel M. M.
收藏  |  浏览/下载：7/0  |  提交时间：2020/05/13