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Pollen PCP-B peptides unlock a stigma peptide–receptor kinase gating mechanism for pollination 期刊论文
Science, 2021
作者:  Chen Liu;  Lianping Shen;  Yu Xiao;  David Vyshedsky;  Chao Peng;  Xiang Sun;  Zhiwen Liu;  Lijun Cheng;  Hua Zhang;  Zhifu Han;  Jijie Chai;  Hen-Ming Wu;  Alice Y. Cheung;  Chao Li
收藏  |  浏览/下载:43/0  |  提交时间:2021/04/12
Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme 期刊论文
Science, 2020
作者:  Shoucai Ma;  Dmitry Lapin;  Li Liu;  Yue Sun;  Wen Song;  Xiaoxiao Zhang;  Elke Logemann;  Dongli Yu;  Jia Wang;  Jan Jirschitzka;  Zhifu Han;  Paul Schulze-Lefert;  Jane E. Parker;  Jijie Chai
收藏  |  浏览/下载:11/0  |  提交时间:2020/12/07
Chiral superconductivity in heavy-fermion metal UTe2 期刊论文
NATURE, 2020, 579 (7800) : 523-527
作者:  Chica, Daniel G.;  He, Yihui;  McCall, Kyle M.;  Chung, Duck Young;  Pak, Rahmi O.;  Trimarchi, Giancarlo;  Liu, Zhifu;  De Lurgio, Patrick M.;  Wessels, Bruce W.;  Kanatzidis, Mercouri G.
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/03

Scanning tunnelling microscopy and spectroscopy measurements show chiral edge states inside the superconducting gap of the heavy-fermion superconductor UTe2, indicating the presence of chiral spin-triplet superconductivity.


Spin-triplet superconductors are condensates of electron pairs with spin 1 and an odd-parity wavefunction(1). An interesting manifestation of triplet pairing is the chiral p-wave state, which is topologically non-trivial and provides a natural platform for realizing Majorana edge modes(2,3). However, triplet pairing is rare in solid-state systems and has not been unambiguously identified in any bulk compound so far. Given that pairing is usually mediated by ferromagnetic spin fluctuations, uranium-based heavy-fermion systems containing f-electron elements, which can harbour both strong correlations and magnetism, are considered ideal candidates for realizing spin-triplet superconductivity(4). Here we present scanning tunnelling microscopy studies of the recently discovered heavy-fermion superconductor UTe2, which has a superconducting transition temperature of 1.6 kelvin(5). We find signatures of coexisting Kondo effect and superconductivity that show competing spatial modulations within one unit cell. Scanning tunnelling spectroscopy at step edges reveals signatures of chiral in-gap states, which have been predicted to exist at the boundaries of topological superconductors. Combined with existing data that indicate triplet pairing in UTe2, the presence of chiral states suggests that UTe2 is a strong candidate for chiral-triplet topological superconductivity.


  
Metabolites released from apoptotic cells act as tissue messengers 期刊论文
NATURE, 2020
作者:  Chica, Daniel G.;  He, Yihui;  McCall, Kyle M.;  Chung, Duck Young;  Pak, Rahmi O.;  Trimarchi, Giancarlo;  Liu, Zhifu;  De Lurgio, Patrick M.;  Wessels, Bruce W.;  Kanatzidis, Mercouri G.
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/03

Caspase-dependent apoptosis accounts for approximately 90% of homeostatic cell turnover in the body(1), and regulates inflammation, cell proliferation, and tissue regeneration(2-4). How apoptotic cells mediate such diverse effects is not fully understood. Here we profiled the apoptotic metabolite secretome and determined its effects on the tissue neighbourhood. We show that apoptotic lymphocytes and macrophages release specific metabolites, while retaining their membrane integrity. A subset of these metabolites is also shared across different primary cells and cell lines after the induction of apoptosis by different stimuli. Mechanistically, the apoptotic metabolite secretome is not simply due to passive emptying of cellular contents and instead is a regulated process. Caspase-mediated opening of pannexin 1 channels at the plasma membrane facilitated the release of a select subset of metabolites. In addition, certain metabolic pathways continued to remain active during apoptosis, with the release of only select metabolites from a given pathway. Functionally, the apoptotic metabolite secretome induced specific gene programs in healthy neighbouring cells, including suppression of inflammation, cell proliferation, and wound healing. Furthermore, a cocktail of apoptotic metabolites reduced disease severity in mouse models of inflammatory arthritis and lung-graft rejection. These data advance the concept that apoptotic cells are not inert cells waiting for removal, but instead release metabolites as '  good-bye'  signals to actively modulate outcomes in tissues.


Apoptotic cells communicate with neighbouring cells by the regulated release of specific metabolites, and a cocktail of select apoptotic metabolites reduces disease severity in mouse models of inflammatory arthritis and lung transplant rejection.


  
Structural decline in China's CO2 emissions through transitions in industry and energy systems 期刊论文
NATURE GEOSCIENCE, 2018, 11 (8) : 551-+
作者:  Guan, Dabo;  Meng, Jing;  Reiner, David M.;  Zhang, Ning;  Shan, Yuli;  Mi, Zhifu;  Shao, Shuai;  Liu, Zhu;  Zhang, Qiang;  Davis, Steven J.
收藏  |  浏览/下载:9/0  |  提交时间:2019/04/09
Structural basis for receptor recognition of pollen tube attraction peptides 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Zhang, Xiaoxiao;  Liu, Weijia;  Nagae, Takuya T.;  Takeuchi, Hidenori;  Zhang, Heqiao;  Han, Zhifu;  Higashiyama, Tetsuya;  Chai, Jijie
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Pattern changes in determinants of Chinese emissions 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2017, 12 (7)
作者:  Mi, Zhifu;  Meng, Jing;  Guan, Dabo;  Shan, Yuli;  Liu, Zhu;  Wang, Yutao;  Feng, Kuishuang;  Wei, Yi-Ming
收藏  |  浏览/下载:12/0  |  提交时间:2019/04/09
CO2 emissions  financial crisis  new normal  input-output analysis  structural decomposition analysis