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Characteristics and source apportionment of ambient single particles in Tianjin, China: The close association between oxalic acid and biomass burning 期刊论文
ATMOSPHERIC RESEARCH, 2020, 237
作者:  Xu, Jiao;  Tian, Yingze;  Cheng, Chunlei;  Wang, Chuang;  Lin, Qiuju;  Li, Mei;  Wang, Xiaofei;  Shi, Guoliang
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/02
Single particle  Oxalic acid  Biomass burning  Source contribution  PMF  SPAMS  
Ground-Based Cloud Classification Using Task-Based Graph Convolutional Network 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (5)
作者:  Liu, Shuang;  Li, Mei;  Zhang, Zhong;  Cao, Xiaozhong;  Durrani, Tariq S.
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/02
Amplification of black carbon light absorption induced by atmospheric aging: temporal variation at seasonal and diel scales in urban Guangzhou 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (4) : 2445-2470
作者:  Sun, Jia Yin;  Wu, Cheng;  Wu, Dui;  Cheng, Chunlei;  Li, Mei;  Li, Lei;  Deng, Tao;  Yu, Jian Zhen;  Li, Yong Jie;  Zhou, Qianni;  Liang, Yue;  Sun, Tianlin;  Song, Lang;  Cheng, Peng;  Yang, Wenda;  Pei, Chenglei;  Chen, Yanning;  Cen, Yanxiang;  Nian, Huiqing;  Zhou, Zhen
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/02
Improved protein structure prediction using potentials from deep learning 期刊论文
NATURE, 2020, 577 (7792) : 706-+
作者:  Ma, Runze;  Cao, Duanyun;  Zhu, Chongqin;  Tian, Ye;  Peng, Jinbo;  Guo, Jing;  Chen, Ji;  Li, Xin-Zheng;  Francisco, Joseph S.;  Zeng, Xiao Cheng;  Xu, Li-Mei;  Wang, En-Ge;  Jiang, Ying
收藏  |  浏览/下载:142/0  |  提交时间:2020/07/03

Protein structure prediction can be used to determine the three-dimensional shape of a protein from its amino acid sequence(1). This problem is of fundamental importance as the structure of a protein largely determines its function(2)  however, protein structures can be difficult to determine experimentally. Considerable progress has recently been made by leveraging genetic information. It is possible to infer which amino acid residues are in contact by analysing covariation in homologous sequences, which aids in the prediction of protein structures(3). Here we show that we can train a neural network to make accurate predictions of the distances between pairs of residues, which convey more information about the structure than contact predictions. Using this information, we construct a potential of mean force(4) that can accurately describe the shape of a protein. We find that the resulting potential can be optimized by a simple gradient descent algorithm to generate structures without complex sampling procedures. The resulting system, named AlphaFold, achieves high accuracy, even for sequences with fewer homologous sequences. In the recent Critical Assessment of Protein Structure Prediction(5) (CASP13)-a blind assessment of the state of the field-AlphaFold created high-accuracy structures (with template modelling (TM) scores(6) of 0.7 or higher) for 24 out of 43 free modelling domains, whereas the next best method, which used sampling and contact information, achieved such accuracy for only 14 out of 43 domains. AlphaFold represents a considerable advance in protein-structure prediction. We expect this increased accuracy to enable insights into the function and malfunction of proteins, especially in cases for which no structures for homologous proteins have been experimentally determined(7).


  
Multi-method determination of the below-cloud wet scavenging coefficients of aerosols in Beijing, China 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (24) : 15569-15581
作者:  Xu, Danhui;  Ge, Baozhu;  Chen, Xueshun;  Sun, Yele;  Cheng, Nianliang;  Li, Mei;  Pan, Xiaole;  Ma, Zhiqiang;  Pan, Yuepeng;  Wang, Zifa
收藏  |  浏览/下载:13/0  |  提交时间:2020/02/17
An Ozone "Pool" in South China: Investigations on Atmospheric Dynamics and Photochemical Processes Over the Pearl River Estuary 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019, 124 (22) : 12340-12355
作者:  Zeren, Yangzong;  Guo, Hai;  Lyu, Xiaopu;  Jiang, Fei;  Wang, Yu;  Liu, Xufei;  Zeng, Lewei;  Li, Mei;  Li, Lei
收藏  |  浏览/下载:8/0  |  提交时间:2020/02/17
ozone pollution  atmospheric dynamics  photochemical reactions  South China  WRF-Chem  
Enrichment of submicron sea-salt-containing particles in small cloud droplets based on single-particle mass spectrometry 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (16) : 10469-10479
作者:  Lin, Qinhao;  Yang, Yuxiang;  Fu, Yuzhen;  Zhang, Guohua;  Jiang, Feng;  Peng, Long;  Lian, Xiufeng;  Liu, Fengxian;  Bi, Xinhui;  Li, Lei;  Chen, Duohong;  Li, Mei;  Ou, Jie;  Tang, Mingjin;  Wang, Xinming;  Peng, Pingan;  Sheng, Guoying
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/27
Impact of particle number and mass size distributions of major chemical components on particle mass scattering efficiency in urban Guangzhou in southern China 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (13) : 8471-8490
作者:  Tao, Jun;  Zhang, Zhisheng;  Wu, Yunfei;  Zhang, Leiming;  Wu, Zhijun;  Cheng, Peng;  Li, Mei;  Chen, Laiguo;  Zhang, Renjian;  Cao, Junji
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
Atmospheric pollution from ships and its impact on local air quality at a port site in Shanghai 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (9) : 6315-6330
作者:  Wang, Xinning;  Shen, Yin;  Lin, Yanfen;  Pan, Jun;  Zhang, Yan;  Louie, Peter K. K.;  Li, Mei;  Fu, Qingyan
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/26
Understanding the catalytic role of oxalic acid in SO3 hydration to form H2SO4 in the atmosphere 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (5) : 2833-2844
作者:  Lv, Guochun;  Sun, Xiaomin;  Zhang, Chenxi;  Li, Mei
收藏  |  浏览/下载:9/0  |  提交时间:2019/04/09