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Multiple Mutualism Effects generate synergistic selection and strengthen fitness alignment in the interaction between legumes, rhizobia and mycorrhizal fungi 期刊论文
Ecology Letters, 2021
作者:  Michelle E. Afkhami;  Maren L. Friesen;  John R. Stinchcombe
收藏  |  浏览/下载：5/0  |  提交时间：2021/06/15
Rapid evolution generates synergism between multiple stressors: Linking theory and an evolution experiment 期刊论文
Global Change Biology, 2021
作者:  James A. Orr;  Pepijn Luijckx;  Jean‐;  Franç;  ois Arnoldi;  Andrew L. Jackson;  Jeremy J. Piggott
收藏  |  浏览/下载：8/0  |  提交时间：2021/05/14
First published peer reviews of the WHO solidarity trials 新闻
来源平台：EurekAlert. 发布日期：2020
作者:  admin
收藏  |  浏览/下载：0/0  |  提交时间：2020/11/20
Keep the data coming 新闻
来源平台：EurekAlert. 发布日期：2020
作者:  admin
收藏  |  浏览/下载：2/0  |  提交时间：2020/11/20
New high-speed test shows how antibiotics combine to kill bacteria 新闻
来源平台：EurekAlert. 发布日期：2020
作者:  admin
收藏  |  浏览/下载：4/0  |  提交时间：2020/09/22
Antagonistic cooperativity between crystal growth modifiers 期刊论文
NATURE, 2020, 577 (7791) : 497-+
作者:  Ma, Wenchuan;  Lutsko, James F.;  Rimer, Jeffrey D.;  Vekilov, Peter G.
收藏  |  浏览/下载：8/0  |  提交时间：2020/07/03

Inhibitor pairs that suppress the crystallization of haematin, which is a part of malaria parasites'  physiology, show unexpected antagonism due to attenuation of step pinning by kink blockers.


Ubiquitous processes in nature and the industry exploit crystallization from multicomponent environments(1-5)  however, laboratory efforts have focused on the crystallization of pure solutes(6,7) and the effects of single growth modifiers(8,9). Here we examine the molecular mechanisms employed by pairs of inhibitors in blocking the crystallization of haematin, which is a model organic compound with relevance to the physiology of malaria parasites(10,11). We use a combination of scanning probe microscopy and molecular modelling to demonstrate that inhibitor pairs, whose constituents adopt distinct mechanisms of haematin growth inhibition, kink blocking and step pinning(12,13), exhibit both synergistic and antagonistic cooperativity depending on the inhibitor combination and applied concentrations. Synergism between two crystal growth modifiers is expected, but the antagonistic cooperativity of haematin inhibitors is not reflected in current crystal growth models. We demonstrate that kink blockers reduce the line tension of step edges, which facilitates both the nucleation of crystal layers and step propagation through the gates created by step pinners. The molecular viewpoint on cooperativity between crystallization modifiers provides guidance on the pairing of modifiers in the synthesis of crystalline materials. The proposed mechanisms indicate strategies to understand and control crystallization in both natural and engineered systems, which occurs in complex multicomponent media(1-3,8,9). In a broader context, our results highlight the complexity of crystal-modifier interactions mediated by the structure and dynamics of the crystal interface.


  
Repeated megaturbidite deposition in Lake Crescent, Washington, USA, triggered by Holocene ruptures of the Lake Creek-Boundary Creek fault system 期刊论文
GEOLOGICAL SOCIETY OF AMERICA BULLETIN, 2019, 131: 2039-2055
作者:  Leithold, Elana L.;  Wegmann, Karl W.;  Bohnenstiehl, D. R.;  Joyner, Catelyn N.;  Pollen, Audrianna F.
收藏  |  浏览/下载：4/0  |  提交时间：2019/11/27
Interactions between wind and fire disturbance in forests: Competing amplifying and buffering effects 期刊论文
FOREST ECOLOGY AND MANAGEMENT, 2019, 436: 117-128
作者:  Cannon, Jeffery B.;  Henderson, Suzanne K.;  Bailey, Michael H.;  Peterson, Chris J.
收藏  |  浏览/下载：7/0  |  提交时间：2019/04/09
Amplifying effects  Antagonism  Buffering effects  Disturbance interactions  Prescribed fire  Synergism  Tornado  Wind damage  
Scientists warn about the dangerous interaction of plant protection products 新闻
来源平台：Science X network. 发布日期：2019
作者:  admin
收藏  |  浏览/下载：4/0  |  提交时间：2019/04/16
Classic and temporal mixture synergism in terrestrial ecosystems: Prevalence, mechanisms and impacts 项目
项目编号：NE/S000194/1； 经费：443703(GBP)； 起止日期：2018 / dc_date_end
项目负责人:  Peter Kille
收藏  |  浏览/下载：16/0  |  提交时间：2019/04/11