GSTDTAP

浏览/检索结果: 共32条,第1-10条 帮助

限定条件                
已选(0)清除 条数/页:   排序方式:
Daily energy expenditure through the human life course 期刊论文
Science, 2021
作者:  Herman Pontzer;  Yosuke Yamada;  Hiroyuki Sagayama;  Philip N. Ainslie;  Lene F. Andersen;  Liam J. Anderson;  Lenore Arab;  Issaad Baddou;  Kweku Bedu-Addo;  Ellen E. Blaak;  Stephane Blanc;  Alberto G. Bonomi;  Carlijn V. C. Bouten;  Pascal Bovet;  Maciej S. Buchowski;  Nancy F. Butte;  Stefan G. Camps;  Graeme L. Close;  Jamie A. Cooper;  Richard Cooper;  Sai Krupa Das;  Lara R. Dugas;  Ulf Ekelund;  Sonja Entringer;  Terrence Forrester;  Barry W. Fudge;  Annelies H Goris;  Michael Gurven;  Catherine Hambly;  Asmaa El Hamdouchi;  Marjije B. Hoos;  Sumei Hu;  Noorjehan Joonas;  Annemiek M. Joosen;  Peter Katzmarzyk;  Kitty P. Kempen;  Misaka Kimura;  William E. Kraus;  Robert F. Kushner;  Estelle V. Lambert;  William R. Leonard;  Nader Lessan;  Corby Martin;  Anine C. Medin;  Erwin P. Meijer;  James C. Morehen;  James P. Morton;  Marian L. Neuhouser;  Teresa A. Nicklas;  Robert M. Ojiambo;  Kirsi H. Pietiläinen;  Yannis P. Pitsiladis;  Jacob Plange-Rhule;  Guy Plasqui;  Ross L. Prentice;  Roberto A. Rabinovich;  Susan B. Racette;  David A. Raichlen;  Eric Ravussin;  Rebecca M. Reynolds;  Susan B. Roberts;  Albertine J. Schuit;  Anders M. Sjödin;  Eric Stice;  Samuel S. Urlacher;  Giulio Valenti;  Ludo M. Van Etten;  Edgar A. Van Mil;  Jonathan C. K. Wells;  George Wilson;  Brian M. Wood;  Jack Yanovski;  Tsukasa Yoshida;  Xueying Zhang;  Alexia J. Murphy-Alford;  Cornelia Loechl;  Amy H. Luke;  Jennifer Rood;  Dale A. Schoeller;  Klaas R. Westerterp;  William W. Wong;  John R. Speakman;  IAEA DLW Database Consortium§
收藏  |  浏览/下载:15/0  |  提交时间:2021/08/17
Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets 期刊论文
Science, 2021
作者:  Rory D. de Vries;  Katharina S. Schmitz;  Francesca T. Bovier;  Camilla Predella;  Jonathan Khao;  Danny Noack;  Bart L. Haagmans;  Sander Herfst;  Kyle N. Stearns;  Jennifer Drew-Bear;  Sudipta Biswas;  Barry Rockx;  Gaël McGill;  N. Valerio Dorrello;  Samuel H. Gellman;  Christopher A. Alabi;  Rik L. de Swart;  Anne Moscona;  Matteo Porotto
收藏  |  浏览/下载:12/0  |  提交时间:2021/04/06
Ecotrons: Powerful and versatile ecosystem analysers for ecology, agronomy and environmental science 期刊论文
Global Change Biology, 2021
作者:  Jacques Roy;  Franç;  ois Rineau;  Hans J. De Boeck;  Ivan Nijs;  Thomas Pü;  tz;  Samuel Abiven;  John A. Arnone;  Craig V. M. Barton;  Natalie Beenaerts;  Nicolas Brü;  ggemann;  Matteo Dainese;  Timo Domisch;  Nico Eisenhauer;  Sarah Garré;  Alban Gebler;  Andrea Ghirardo;  Richard L. Jasoni;  George Kowalchuk;  Damien Landais;  Stuart H. Larsen;  Vincent Leemans;  Jean‐;  Franç;  ois Le Galliard;  Bernard Longdoz;  Florent Massol;  Teis N. Mikkelsen;  Georg Niedrist;  Clé;  ment Piel;  Olivier Ravel;  Joana Sauze;  Anja Schmidt;  ;  rg‐;  Peter Schnitzler;  Leonardo H. Teixeira;  Mark G. Tjoelker;  Wolfgang W. Weisser;  Barbro Winkler;  Alexandru Milcu
收藏  |  浏览/下载:13/0  |  提交时间:2021/02/17
Spatial patterns and drivers of non‐perennial flow regimes in the contiguous U.S. 期刊论文
Geophysical Research Letters, 2020
作者:  John C. Hammond;  Margaret Zimmer;  Margaret Shanafield;  Kendra Kaiser;  Sarah E. Godsey;  Meryl C. Mims;  Samuel C. Zipper;  Ryan M. Burrows;  Stephanie K. Kampf;  Walter Dodds;  C. Nathan Jones;  Corey A. Krabbenhoft;  Kate S. Boersma;  Thibault Datry;  Julian D. Olden;  George H. Allen;  Adam N. Price;  Katie Costigan;  Rebecca Hale;  Adam S. Ward;  Daniel C. Allen
收藏  |  浏览/下载:11/0  |  提交时间:2020/12/22
Characteristics of Energetic Electrons Near Active Magnetotail Reconnection Sites: Tracers of a Complex Magnetic Topology and Evidence of Localized Acceleration 期刊论文
Geophysical Research Letters, 2020
作者:  Drew L. Turner;  Ian J. Cohen;  Samuel T. Bingham;  Grant K. Stephens;  Mikhail I. Sitnov;  Barry H. Mauk;  Richard E. Denton;  Trevor W. Leonard;  Joseph F. Fennell;  J. Bernard Blake;  Roy B. Torbert;  James L. Burch
收藏  |  浏览/下载:13/0  |  提交时间:2020/12/22
Evolution and epidemic spread of SARS-CoV-2 in Brazil 期刊论文
Science, 2020
作者:  Darlan S. Candido;  Ingra M. Claro;  Jaqueline G. de Jesus;  William M. Souza;  Filipe R. R. Moreira;  Simon Dellicour;  Thomas A. Mellan;  Louis du Plessis;  Rafael H. M. Pereira;  Flavia C. S. Sales;  Erika R. Manuli;  Julien Thézé;  Luiz Almeida;  Mariane T. Menezes;  Carolina M. Voloch;  Marcilio J. Fumagalli;  Thaís M. Coletti;  Camila A. M. da Silva;  Mariana S. Ramundo;  Mariene R. Amorim;  Henrique H. Hoeltgebaum;  Swapnil Mishra;  Mandev S. Gill;  Luiz M. Carvalho;  Lewis F. Buss;  Carlos A. Prete;  Jordan Ashworth;  Helder I. Nakaya;  Pedro S. Peixoto;  Oliver J. Brady;  Samuel M. Nicholls;  Amilcar Tanuri;  Átila D. Rossi;  Carlos K. V. Braga;  Alexandra L. Gerber;  Ana Paula de C. Guimarães;  Nelson Gaburo;  Cecila Salete Alencar;  Alessandro C. S. Ferreira;  Cristiano X. Lima;  José Eduardo Levi;  Celso Granato;  Giulia M. Ferreira;  Ronaldo S. Francisco;  Fabiana Granja;  Marcia T. Garcia;  Maria Luiza Moretti;  Mauricio W. Perroud;  Terezinha M. P. P. Castiñeiras;  Carolina S. Lazari;  Sarah C. Hill;  Andreza Aruska de Souza Santos;  Camila L. Simeoni;  Julia Forato;  Andrei C. Sposito;  Angelica Z. Schreiber;  Magnun N. N. Santos;  Camila Zolini de Sá;  Renan P. Souza;  Luciana C. Resende-Moreira;  Mauro M. Teixeira;  Josy Hubner;  Patricia A. F. Leme;  Rennan G. Moreira;  Maurício L. Nogueira;  Brazil-UK Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology Genomic Network;  Neil M. Ferguson;  Silvia F. Costa;  José Luiz Proenca-Modena;  Ana Tereza R. Vasconcelos;  Samir Bhatt;  Philippe Lemey;  Chieh-Hsi Wu;  Andrew Rambaut;  Nick J. Loman;  Renato S. Aguiar;  Oliver G. Pybus;  Ester C. Sabino;  Nuno Rodrigues Faria
收藏  |  浏览/下载:13/0  |  提交时间:2020/09/08
Distributed Acoustic Sensing of Seismic Properties in a Borehole Drilled on a Fast-Flowing Greenlandic Outlet Glacier 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (13)
作者:  Booth, Adam D.;  Christoffersen, Poul;  Schoonman, Charlotte;  Clarke, Andy;  Hubbard, Bryn;  Law, Robert;  Doyle, Samuel H.;  Chudley, Thomas R.;  Chalari, Athena
收藏  |  浏览/下载:10/0  |  提交时间:2020/06/09
Distributed Acoustic Sensing (DAS)  Vertical Seismic Profile (VSP)  Greenland Ice Sheet  anisotropy  subglacial sediment  borehole surveying  
Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system 期刊论文
NATURE, 2020, 577 (7789) : 271-+
作者:  Halpin-Healy, Tyler S.;  Klompe, Sanne E.;  Sternberg, Samuel H.;  Fernandez, Israel S.
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/03

Bacteria use adaptive immune systems encoded by CRISPR and Cas genes to maintain genomic integrity when challenged by pathogens and mobile genetic elements(1-3). Type I CRISPR-Cas systems typically target foreign DNA for degradation via joint action of the ribonucleoprotein complex Cascade and the helicase-nuclease Cas3(4,5), but nuclease-deficient type I systems lacking Cas3 have been repurposed for RNA-guided transposition by bacterial Tn7-like transposons(6,7). How CRISPR- and transposon-associated machineries collaborate during DNA targeting and insertion remains unknown. Here we describe structures of a TniQ-Cascade complex encoded by the Vibrio cholerae Tn6677 transposon using cryo-electron microscopy, revealing the mechanistic basis of this functional coupling. The cryo-electron microscopy maps enabled de novo modelling and refinement of the transposition protein TniQ, which binds to the Cascade complex as a dimer in a head-to-tail configuration, at the interface formed by Cas6 and Cas7 near the 3'  end of the CRISPR RNA (crRNA). The natural Cas8-Cas5 fusion protein binds the 5'  crRNA handle and contacts the TniQ dimer via a flexible insertion domain. A target DNA-bound structure reveals critical interactions necessary for protospacer-adjacent motif recognition and R-loop formation. This work lays the foundation for a structural understanding of how DNA targeting by TniQ-Cascade leads to downstream recruitment of additional transposase proteins, and will guide protein engineering efforts to leverage this system for programmable DNA insertions in genome-engineering applications.


  
The seismicity of Mars 期刊论文
NATURE GEOSCIENCE, 2020, 13 (3) : 205-+
作者:  Giardini, D.;  Lognonne, P.;  Banerdt, W. B.;  Pike, W. T.;  Christensen, U.;  Ceylan, S.;  Clinton, J. F.;  van Driel, M.;  Staehler, S. C.;  Boese, M.;  Garcia, R. F.;  Khan, A.;  Panning, M.;  Perrin, C.;  Banfield, D.;  Beucler, E.;  Charalambous, C.;  Euchner, F.;  Horleston, A.;  Jacob, A.;  Kawamura, T.;  Kedar, S.;  Mainsant, G.;  Scholz, J. -R.;  Smrekar, S. E.;  Spiga, A.;  Agard, C.;  Antonangeli, D.;  Barkaoui, S.;  Barrett, E.;  Combes, P.;  Conejero, V.;  Daubar, I.;  Drilleau, M.;  Ferrier, C.;  Gabsi, T.;  Gudkova, T.;  Hurst, K.;  Karakostas, F.;  King, S.;  Knapmeyer, M.;  Knapmeyer-Endrun, B.;  Llorca-Cejudo, R.;  Lucas, A.;  Luno, L.;  Margerin, L.;  McClean, J. B.;  Mimoun, D.;  Murdoch, N.;  Nimmo, F.;  Nonon, M.;  Pardo, C.;  Rivoldini, A.;  Manfredi, J. A. Rodriguez;  Samuel, H.;  Schimmel, M.;  Stott, A. E.;  Stutzmann, E.;  Teanby, N.;  Warren, T.;  Weber, R. C.;  Wieczorek, M.;  Yana, C.
收藏  |  浏览/下载:11/0  |  提交时间:2020/05/13
Fast two-qubit logic with holes in germanium 期刊论文
NATURE, 2020, 577 (7791) : 487-+
作者:  Halpin-Healy, Tyler S.;  Klompe, Sanne E.;  Sternberg, Samuel H.;  Fernandez, Israel S.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/03

Universal quantum information processing requires the execution of single-qubit and two-qubit logic. Across all qubit realizations(1), spin qubits in quantum dots have great promise to become the central building block for quantum computation(2). Excellent quantum dot control can be achieved in gallium arsenide(3-5), and high-fidelity qubit rotations and two-qubit logic have been demonstrated in silicon(6-9), but universal quantum logic implemented with local control has yet to be demonstrated. Here we make this step by combining all of these desirable aspects using hole quantum dots in germanium. Good control over tunnel coupling and detuning is obtained by exploiting quantum wells with very low disorder, enabling operation at the charge symmetry point for increased qubit performance. Spin-orbit coupling obviates the need for microscopic elements close to each qubit and enables rapid qubit control with driving frequencies exceeding 100 MHz. We demonstrate a fast universal quantum gate set composed of single-qubit gates with a fidelity of 99.3 per cent and a gate time of 20 nanoseconds, and two-qubit logic operations executed within 75 nanoseconds. Planar germanium has thus matured within a year from a material that can host quantum dots to a platform enabling two-qubit logic, positioning itself as an excellent material for use in quantum information applications.


Spin qubits based on hole states in strained germanium could offer the most scalable platform for quantum computation.