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A remnant planetary core in the hot-Neptune desert 期刊论文
NATURE, 2020, 583 (7814) : 39-+
作者:  David J. Armstrong;  Thé;  o A. Lopez;  Vardan Adibekyan;  Richard A. Booth;  Edward M. Bryant;  Karen A. Collins;  Magali Deleuil;  Alexandre Emsenhuber;  Chelsea X. Huang;  George W. King;  Jorge Lillo-Box;  Jack J. Lissauer;  Elisabeth Matthews;  Olivier Mousis;  Louise D. Nielsen;  Hugh Osborn;  Jon Otegi;  Nuno C. Santos;  ;  rgio G. Sousa;  Keivan G. Stassun;  Dimitri Veras;  Carl Ziegler;  Jack S. Acton;  Jose M. Almenara;  David R. Anderson;  David Barrado;  Susana C. C. Barros;  Daniel Bayliss;  Claudia Belardi;  Francois Bouchy;  ;  sar Briceñ;  o;  Matteo Brogi;  David J. A. Brown;  Matthew R. Burleigh;  Sarah L. Casewell;  Alexander Chaushev;  David R. Ciardi;  Kevin I. Collins;  Knicole D. Coló;  n;  Benjamin F. Cooke;  Ian J. M. Crossfield;  Rodrigo F. Dí;  az;  Elisa Delgado Mena;  Olivier D. S. Demangeon;  Caroline Dorn;  Xavier Dumusque;  Philipp Eigmü;  ller;  Michael Fausnaugh;  Pedro Figueira;  Tianjun Gan;  Siddharth Gandhi;  Samuel Gill;  Erica J. Gonzales;  Michael R. Goad;  Maximilian N. Gü;  nther;  Ravit Helled;  Saeed Hojjatpanah;  Steve B. Howell;  James Jackman;  James S. Jenkins;  Jon M. Jenkins;  Eric L. N. Jensen;  Grant M. Kennedy;  David W. Latham;  Nicholas Law;  Monika Lendl;  Michael Lozovsky;  Andrew W. Mann;  Maximiliano Moyano;  James McCormac;  Farzana Meru;  Christoph Mordasini;  Ares Osborn;  Don Pollacco;  Didier Queloz;  Liam Raynard;  George R. Ricker;  Pamela Rowden;  Alexandre Santerne;  Joshua E. Schlieder;  Sara Seager;  Lizhou Sha;  Thiam-Guan Tan;  Rosanna H. Tilbrook;  Eric Ting;  Sté;  phane Udry;  Roland Vanderspek;  Christopher A. Watson;  Richard G. West;  Paul A. Wilson;  Joshua N. Winn;  Peter Wheatley;  Jesus Noel Villasenor;  Jose I. Vines;  Zhuchang Zhan
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/06

The interiors of giant planets remain poorly understood. Even for the planets in the Solar System, difficulties in observation lead to large uncertainties in the properties of planetary cores. Exoplanets that have undergone rare evolutionary processes provide a route to understanding planetary interiors. Planets found in and near the typically barren hot-Neptune '  desert'  (1,2)(a region in mass-radius space that contains few planets) have proved to be particularly valuable in this regard. These planets include HD149026b(3), which is thought to have an unusually massive core, and recent discoveries such as LTT9779b(4)and NGTS-4b(5), on which photoevaporation has removed a substantial part of their outer atmospheres. Here we report observations of the planet TOI-849b, which has a radius smaller than Neptune'  s but an anomalously large mass of39.1-2.6+2.7Earth masses and a density of5.2-0.8+0.7grams per cubic centimetre, similar to Earth'  s. Interior-structure models suggest that any gaseous envelope of pure hydrogen and helium consists of no more than3.9-0.9+0.8 per cent of the total planetary mass. The planet could have been a gas giant before undergoing extreme mass loss via thermal self-disruption or giant planet collisions, or it could have avoided substantial gas accretion, perhaps through gap opening or late formation(6). Although photoevaporation rates cannot account for the mass loss required to reduce a Jupiter-like gas giant, they can remove a small (a few Earth masses) hydrogen and helium envelope on timescales of several billion years, implying that any remaining atmosphere on TOI-849b is likely to be enriched by water or other volatiles from the planetary interior. We conclude that TOI-849b is the remnant core of a giant planet.


Observations of TOI-849b reveal a radius smaller than Neptune'  s but a large mass of about 40 Earth masses, indicating that the planet is the remnant core of a gas giant.


  
Brain control of humoral immune responses amenable to behavioural modulation 期刊论文
NATURE, 2020, 581 (7807)
作者:  Yang, C. H.;  Leon, R. C. C.;  Hwang, J. C. C.;  Saraiva, A.;  Tanttu, T.;  Huang, W.;  Lemyre, J. Camirand;  Chan, K. W.;  Tan, K. Y.;  Hudson, F. E.;  Itoh, K. M.;  Morello, A.;  Pioro-Ladriere, M.;  Laucht, A.;  Dzurak, A. S.
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/03

It has been speculated that brain activities might directly control adaptive immune responses in lymphoid organs, although there is little evidence for this. Here we show that splenic denervation in mice specifically compromises the formation of plasma cells during a T cell-dependent but not T cell-independent immune response. Splenic nerve activity enhances plasma cell production in a manner that requires B-cell responsiveness to acetylcholine mediated by the alpha 9 nicotinic receptor, and T cells that express choline acetyl transferase(1,2) probably act as a relay between the noradrenergic nerve and acetylcholine-responding B cells. We show that neurons in the central nucleus of the amygdala (CeA) and the paraventricular nucleus (PVN) that express corticotropin-releasing hormone (CRH) are connected to the splenic nerve  ablation or pharmacogenetic inhibition of these neurons reduces plasma cell formation, whereas pharmacogenetic activation of these neurons increases plasma cell abundance after immunization. In a newly developed behaviour regimen, mice are made to stand on an elevated platform, leading to activation of CeA and PVN CRH neurons and increased plasma cell formation. In immunized mice, the elevated platform regimen induces an increase in antigen-specific IgG antibodies in a manner that depends on CRH neurons in the CeA and PVN, an intact splenic nerve, and B cell expression of the alpha 9 acetylcholine receptor. By identifying a specific brain-spleen neural connection that autonomically enhances humoral responses and demonstrating immune stimulation by a bodily behaviour, our study reveals brain control of adaptive immunity and suggests the possibility to enhance immunocompetency by behavioural intervention.


Neuronal activities in the central amygdala and paraventricular nucleus are transmitted via the splenic nerve to increase plasma cell formation after immunization, and this process can be behaviourally enhanced in mice.


  
Intraplate volcanism originating from upwelling hydrous mantle transition zone 期刊论文
NATURE, 2020
作者:  Calabrese, Claudia;  Davidson, Natalie R.;  Demircioglu, Deniz;  Fonseca, Nuno A.;  He, Yao;  Kahles, Andre;  Kjong-Van Lehmann;  Liu, Fenglin;  Shiraishi, Yuichi;  Soulette, Cameron M.;  Urban, Lara;  Greger, Liliana;  Li, Siliang;  Liu, Dongbing;  Perry, Marc D.;  Xiang, Qian;  Zhang, Fan;  Zhang, Junjun;  Bailey, Peter;  Erkek, Serap;  Hoadley, Katherine A.;  Hou, Yong;  Huska, Matthew R.;  Kilpinen, Helena;  Korbel, Jan O.;  Marin, Maximillian G.;  Markowski, Julia;  Nandi, Tannistha;  Pan-Hammarstrom, Qiang;  Pedamallu, Chandra Sekhar;  Siebert, Reiner;  Stark, Stefan G.;  Su, Hong;  Tan, Patrick;  Waszak, Sebastian M.;  Yung, Christina;  Zhu, Shida;  Awadalla, Philip;  Creighton, Chad J.;  Meyerson, Matthew;  Ouellette, B. F. Francis;  Wu, Kui;  Yang, Huanming;  Brazma, Alvis;  Brooks, Angela N.;  Goke, Jonathan;  Raetsch, Gunnar;  Schwarz, Roland F.;  Stegle, Oliver;  Zhang, Zemin
收藏  |  浏览/下载:72/0  |  提交时间:2020/05/13

Most magmatism occurring on Earth is conventionally attributed to passive mantle upwelling at mid-ocean ridges, to slab devolatilization at subduction zones, or to mantle plumes. However, the widespread Cenozoic intraplate volcanism in northeast China(1-3) and the young petit-spot volcanoes(4-7) offshore of the Japan Trench cannot readily be associated with any of these mechanisms. In addition, the mantle beneath these types of volcanism is characterized by zones of anomalously low seismic velocity above and below the transition zone(8-12) (a mantle level located at depths between 410 and 660 kilometres). A comprehensive interpretation of these phenomena is lacking. Here we show that most (or possibly all) of the intraplate and petit-spot volcanism and low-velocity zones around the Japanese subduction zone can be explained by the Cenozoic interaction of the subducting Pacific slab with a hydrous mantle transition zone. Numerical modelling indicates that 0.2 to 0.3 weight per cent of water dissolved in mantle minerals that are driven out from the transition zone in response to subduction and retreat of a tectonic plate is sufficient to reproduce the observations. This suggests that a critical amount of water may have accumulated in the transition zone around this subduction zone, as well as in others of the Tethyan tectonic belt(13) that are characterized by intraplate or petit-spot volcanism and low-velocity zones in the underlying mantle.


The widespread intraplate volcanism in northeast China and the unusual '  petit-spot'  volcanoes offshore Japan could have resulted from the interaction of the subducting Pacific slab with a hydrous mantle transition zone.


  
Thermal unequilibrium of strained black CsPbI3 thin films 期刊论文
SCIENCE, 2019, 365 (6454) : 679-+
作者:  Steele, Julian A.;  Jin, Handong;  Dovgaliuk, Iurii;  Berger, Robert F.;  Braeckevelt, Tom;  Yuan, Haifeng;  Martin, Cristina;  Solano, Eduardo;  Lejaeghere, Kurt;  Rogge, Sven M. J.;  Notebaert, Charlotte;  Vandezande, Wouter;  Janssen, Kris P. F.;  Goderis, Bart;  Debroye, Elke;  Wang, Ya-Kun;  Dong, Yitong;  Ma, Dongxin;  Saidaminov, Makhsud;  Tan, Hairen;  Lu, Zhenghong;  Dyadkin, Vadim;  Chernyshov, Dmitry;  Van Speybroeck, Veronique;  Sargent, Edward H.;  Hofkens, Johan;  Roeffaers, Maarten B. J.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Hydrodealkenylative C(sp(3))-C(sp(2)) bond fragmentation 期刊论文
SCIENCE, 2019, 364 (6441) : 681-+
作者:  Smaligo, Andrew J.;  Swain, Manisha;  Quintana, Jason C.;  Tan, Mikayla F.;  Kim, Danielle A.;  Kwon, Ohyun
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/27
Rainfall variations in central Indo-Pacific over the past 2,700 y 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (35) : 17201-17206
作者:  Tan, Liangcheng;  Shen, Chuan-Chou;  Lowemark, Ludvig;  Chawchai, Sakonvan;  Edwards, R. Lawrence;  Cai, Yanjun;  Breitenbach, Sebastian F. M.;  Cheng, Hai J.;  Chou, Yu-Chen;  Duerrast, Helmut;  Partin, Judson W.;  Cai, Wenju;  Chabangborn, Akkaneewut;  Gao, Yongli;  Kwiecien, Ola;  Wu, Chung-Che;  Shi, Zhengguo;  Hsu, Huang-Hsiung;  Wohlfarth, Barbara
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/27
central Indo-Pacific  rainfall  ENSO  ITCZ  stalagmite  
Field-deployable viral diagnostics using CRISPR-Cas13 期刊论文
SCIENCE, 2018, 360 (6387) : 444-448
作者:  Myhrvold, Cameron;  Freije, Catherine A.;  Gootenberg, Jonathan S.;  Abudayyeh, Omar O.;  Metsky, Hayden C.;  Durbin, Ann F.;  Kellner, Max J.;  Tan, Amanda L.;  Paul, Lauren M.;  Parham, Leda A.;  Garcia, Kimberly F.;  Barnes, Kayla G.;  Chak, Bridget;  Mondini, Adriano;  Nogueira, Mauricio L.;  Isern, Sharon;  Michael, Scott F.;  Lorenzana, Ivette;  Yozwiak, Nathan L.;  MacInnis, Bronwyn L.;  Bosch, Irene;  Gehrke, Lee;  Zhang, Feng;  Sabeti, Pardis C.
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/27
Paternally inherited cis-regulatory structural variants are associated with autism 期刊论文
SCIENCE, 2018, 360 (6386) : 327-330
作者:  Brandler, William M.;  Antaki, Danny;  Gujral, Madhusudan;  Kleiber, Morgan L.;  Whitney, Joe;  Maile, Michelle S.;  Hong, Oanh;  Chapman, Timothy R.;  Tan, Shirley;  Tandon, Prateek;  Pang, Timothy;  Tang, Shih C.;  Vaux, Keith K.;  Yang, Yan;  Harrington, Eoghan;  Juul, Sissel;  Turner, Daniel J.;  Thiruvahindrapuram, Bhooma;  Kaur, Gaganjot;  Wang, Zhuozhi;  Kingsmore, Stephen F.;  Gleeson, Joseph G.;  Bisson, Denis;  Kakaradov, Boyko;  Telenti, Amalio;  Venter, J. Craig;  Corominas, Roser;  Toma, Claudio;  Cormand, Bru;  Rueda, Isabel;  Guijarro, Silvina;  Messer, Karen S.;  Nievergelt, Caroline M.;  Arranz, Maria J.;  Courchesne, Eric;  Pierce, Karen;  Muotri, Alysson R.;  Iakoucheva, Lilia M.;  Hervas, Amaia;  Scherer, Stephen W.;  Corsello, Christina;  Sebat, Jonathan
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/27
Effects of NOx and SO2 on the secondary organic aerosol formation from photooxidation of alpha-pinene and limonene 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2018, 18 (3) : 1611-1628
作者:  Zhao, Defeng;  Schmitt, Sebastian H.;  Wang, Mingjin;  Acir, Ismail-Hakki;  Tillmann, Ralf;  Tan, Zhaofeng;  Novelli, Anna;  Fuchs, Hendrik;  Pullinen, Iida;  Wegener, Robert;  Rohrer, Franz;  Wildt, Juergen;  Kiendler-Scharr, Astrid;  Wahner, Andreas;  Mentel, Thomas F.
收藏  |  浏览/下载:4/0  |  提交时间:2019/04/09
An overview of mesoscale aerosol processes, comparisons, and validation studies from DRAGON networks 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2018, 18 (2) : 655-671
作者:  Holben, Brent N.;  Kim, Jhoon;  Sano, Itaru;  Mukai, Sonoyo;  Eck, Thomas F.;  Giles, David M.;  Schafer, Joel S.;  Sinyuk, Aliaksandr;  Slutsker, Ilya;  Smirnov, Alexander;  Sorokin, Mikhail;  Anderson, Bruce E.;  Che, Huizheng;  Choi, Myungje;  Crawford, James H.;  Ferrare, Richard A.;  Garay, Michael J.;  Jeong, Ukkyo;  Kim, Mijin;  Kim, Woogyung;  Knox, Nichola;  Li, Zhengqiang;  Lim, Hwee S.;  Liu, Yang;  Maring, Hal;  Nakata, Makiko;  Pickering, Kenneth E.;  Piketh, Stuart;  Redemann, Jens;  Reid, Jeffrey S.;  Salinas, Santo;  Seo, Sora;  Tan, Fuyi;  Tripathi, Sachchida N.;  Toon, Owen B.;  Xiao, Qingyang
收藏  |  浏览/下载:9/0  |  提交时间:2019/04/09