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Recycling and metabolic flexibility dictate life in the lower oceanic crust 期刊论文
NATURE, 2020, 579 (7798) : 250-+
作者:  Zhou, Peng;  Yang, Xing-Lou;  Wang, Xian-Guang;  Hu, Ben;  Zhang, Lei;  Zhang, Wei;  Si, Hao-Rui;  Zhu, Yan;  Li, Bei;  Huang, Chao-Lin;  Chen, Hui-Dong;  Chen, Jing;  Luo, Yun;  Guo, Hua;  Jiang, Ren-Di;  Liu, Mei-Qin;  Chen, Ying;  Shen, Xu-Rui;  Wang, Xi;  Zheng, Xiao-Shuang;  Zhao, Kai;  Chen, Quan-Jiao;  Deng, Fei;  Liu, Lin-Lin;  Yan, Bing;  Zhan, Fa-Xian;  Wang, Yan-Yi;  Xiao, Geng-Fu;  Shi, Zheng-Li
收藏  |  浏览/下载：37/0  |  提交时间：2020/05/13

The lithified lower oceanic crust is one of Earth'  s last biological frontiers as it is difficult to access. It is challenging for microbiota that live in marine subsurface sediments or igneous basement to obtain sufficient carbon resources and energy to support growth(1-3) or to meet basal power requirements(4) during periods of resource scarcity. Here we show how limited and unpredictable sources of carbon and energy dictate survival strategies used by low-biomass microbial communities that live 10-750 m below the seafloor at Atlantis Bank, Indian Ocean, where Earth'  s lower crust is exposed at the seafloor. Assays of enzyme activities, lipid biomarkers, marker genes and microscopy indicate heterogeneously distributed and viable biomass with ultralow cell densities (fewer than 2,000 cells per cm(3)). Expression of genes involved in unexpected heterotrophic processes includes those with a role in the degradation of polyaromatic hydrocarbons, use of polyhydroxyalkanoates as carbon-storage molecules and recycling of amino acids to produce compounds that can participate in redox reactions and energy production. Our study provides insights into how microorganisms in the plutonic crust are able to survive within fractures or porous substrates by coupling sources of energy to organic and inorganic carbon resources that are probably delivered through the circulation of subseafloor fluids or seawater.


  
Strongly correlated quantum walks with a 12-qubit superconducting processor 期刊论文
SCIENCE, 2019, 364 (6442) : 753-+
作者:  Yan, Zhiguang;  Zhang, Yu-Ran;  Gong, Ming;  Wu, Yulin;  Zheng, Yarui;  Li, Shaowei;  Wang, Can;  Liang, Futian;  Lin, Jin;  Xu, Yu;  Guo, Cheng;  Sun, Lihua;  Peng, Cheng-Zhi;  Xia, Keyu;  Deng, Hui;  Rong, Hao;  You, J. Q.;  Nori, Franco;  Fan, Heng;  Zhu, Xiaobo;  Pan, Jian-Wei
收藏  |  浏览/下载：16/0  |  提交时间：2019/11/27
Double-negative-index ceramic aerogels for thermal superinsulation 期刊论文
SCIENCE, 2019, 363 (6428) : 723-+
作者:  Xu, Xiang;  Zhang, Qiangqiang;  Hao, Menglong;  Hu, Yuan;  Lin, Zhaoyang;  Peng, Lele;  Wang, Tao;  Ren, Xuexin;  Wang, Chen;  Zhao, Zipeng;  Wan, Chengzhang;  Fei, Huilong;  Wang, Lei;  Zhu, Jian;  Sun, Hongtao;  Chen, Wenli;  Du, Tao;  Deng, Biwei;  Cheng, Gary J.;  Shakir, Imran;  Dames, Chris;  Fisher, Timothy S.;  Zhang, Xiang;  Li, Hui;  Huang, Yu;  Duan, Xiangfeng
收藏  |  浏览/下载：15/0  |  提交时间：2019/11/27
Modular radical cross-coupling with sulfones enables access to sp(3)-rich (fluoro)alkylated scaffolds 期刊论文
SCIENCE, 2018, 360 (6384) : 75-80
作者:  Merchant, Rohan R.;  Edwards, Jacob T.;  Qin, Tian;  Kruszyk, Monika M.;  Bi, Cheng;  Che, Guanda;  Bao, Deng-Hui;  Qiao, Wenhua;  Sun, Lijie;  Collins, Michael R.;  Fadeyi, Olugbeminiyi O.;  Gallego, Gary M.;  Mousseau, James J.;  Nuhant, Philippe;  Baran, Phil S.
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/27
A central neural circuit for itch sensation 期刊论文
SCIENCE, 2017, 357 (6352) : 695-698
作者:  Mu, Di;  Deng, Juan;  Liu, Ke-Fei;  Wu, Zhen-Yu;  Shi, Yu-Feng;  Guo, Wei-Min;  Mao, Qun-Quan;  Liu, Xing-Jun;  Li, Hui;  Sun, Yan-Gang
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 期刊论文
SCIENCE, 2017, 356 (6342) : 1084-1087
作者:  van Esbroeck, Annelot C. M.;  Janssen, Antonius P. A.;  Cognetta, Armand B., III;  Ogasawara, Daisuke;  Shpak, Guy;  van der Kroeg, Mark;  Kantae, Vasudev;  Baggelaar, Marc P.;  de Vrij, Femke M. S.;  Deng, Hui;  Allara, Marco;  Fezza, Filomena;  Lin, Zhanmin;  van der Wel, Tom;  Soethoudt, Marjolein;  Mock, Elliot D.;  den Dulk, Hans;  Baak, Ilse L.;  Florea, Bogdan I.;  Hendriks, Giel;  de Petrocellis, Luciano;  Overkleeft, Herman S.;  Hankemeier, Thomas;  De Zeeuw, Chris I.;  Di Marzo, Vincenzo;  Maccarrone, Mauro;  Cravatt, Benjamin F.;  Kushner, Steven A.;  van der Stelt, Mario
收藏  |  浏览/下载：11/0  |  提交时间：2019/11/27