GSTDTAP

浏览/检索结果: 共6条,第1-6条 帮助

限定条件    
已选(0)清除 条数/页:   排序方式:
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity 期刊论文
Science, 2020
作者:  Ellen Shrock;  Eric Fujimura;  Tomasz Kula;  Richard T. Timms;  I-Hsiu Lee;  Yumei Leng;  Matthew L. Robinson;  Brandon M. Sie;  Mamie Z. Li;  Yuezhou Chen;  Jennifer Logue;  Adam Zuiani;  Denise McCulloch;  Felipe J. N. Lelis;  Stephanie Henson;  Daniel R. Monaco;  Meghan Travers;  Shaghayegh Habibi;  William A. Clarke;  Patrizio Caturegli;  Oliver Laeyendecker;  Alicja Piechocka-Trocha;  Jonathan Z. Li;  Ashok Khatri;  Helen Y. Chu;  MGH COVID-19 Collection &;  amp;  Processing Team16‡;  Alexandra-Chloé Villani;  Kyle Kays;  Marcia B. Goldberg;  Nir Hacohen;  Michael R. Filbin;  Xu G. Yu;  Bruce D. Walker;  Duane R. Wesemann;  H. Benjamin Larman;  James A. Lederer;  Stephen J. Elledge
收藏  |  浏览/下载:11/0  |  提交时间:2020/11/30
Premature mortality related to United States cross-state air pollution 期刊论文
NATURE, 2020, 578 (7794) : 261-+
作者:  Helmink, Beth A.;  Reddy, Sangeetha M.;  Gao, Jianjun;  Zhang, Shaojun;  Basar, Rafet;  Thakur, Rohit;  Yizhak, Keren;  Sade-Feldman, Moshe;  Blando, Jorge;  Han, Guangchun;  Gopalakrishnan, Vancheswaran;  Xi, Yuanxin;  Zhao, Hao;  Amaria, Rodabe N.;  Tawbi, Hussein A.;  Cogdill, Alex P.;  Liu, Wenbin;  LeBleu, Valerie S.;  Kugeratski, Fernanda G.;  Patel, Sapna;  Davies, Michael A.;  Hwu, Patrick;  Lee, Jeffrey E.;  Gershenwald, Jeffrey E.;  Lucci, Anthony;  Arora, Reetakshi;  Woodman, Scott;  Keung, Emily Z.;  Gaudreau, Pierre-Olivier;  Reuben, Alexandre;  Spencer, Christine N.;  Burton, Elizabeth M.;  Haydu, Lauren E.;  Lazar, Alexander J.;  Zapassodi, Roberta;  Hudgens, Courtney W.;  Ledesma, Deborah A.;  Ong, SuFey;  Bailey, Michael;  Warren, Sarah;  Rao, Disha;  Krijgsman, Oscar;  Rozeman, Elisa A.;  Peeper, Daniel;  Blank, Christian U.;  Schumacher, Ton N.;  Butterfield, Lisa H.;  Zelazowska, Monika A.;  McBride, Kevin M.;  Kalluri, Raghu;  Allison, James;  Petitprez, Florent;  Fridman, Wolf Herman;  Sautes-Fridman, Catherine;  Hacohen, Nir;  Rezvani, Katayoun;  Sharma, Padmanee;  Tetzlaff, Michael T.;  Wang, Linghua;  Wargo, Jennifer A.
收藏  |  浏览/下载:37/0  |  提交时间:2020/05/13

Outdoor air pollution adversely affects human health and is estimated to be responsible for five to ten per cent of the total annual premature mortality in the contiguous United States(1-3). Combustion emissions from a variety of sources, such as power generation or road traffic, make a large contribution to harmful air pollutants such as ozone and fine particulate matter (PM2.5)(4). Efforts to mitigate air pollution have focused mainly on the relationship between local emission sources and local air quality(2). Air quality can also be affected by distant emission sources, however, including emissions from neighbouring federal states(5,6). This cross-state exchange of pollution poses additional regulatory challenges. Here we quantify the exchange of air pollution among the contiguous United States, and assess its impact on premature mortality that is linked to increased human exposure to PM2.5 and ozone from seven emission sectors for 2005 to 2018. On average, we find that 41 to 53 per cent of air-quality-related premature mortality resulting from a state'  s emissions occurs outside that state. We also find variations in the cross-state contributions of different emission sectors and chemical species to premature mortality, and changes in these variations over time. Emissions from electric power generation have the greatest cross-state impacts as a fraction of their total impacts, whereas commercial/residential emissions have the smallest. However, reductions in emissions from electric power generation since 2005 have meant that, by 2018, cross-state premature mortality associated with the commercial/residential sector was twice that associated with power generation. In terms of the chemical species emitted, nitrogen oxides and sulfur dioxide emissions caused the most cross-state premature deaths in 2005, but by 2018 primary PM2.5 emissions led to cross-state premature deaths equal to three times those associated with sulfur dioxide emissions. These reported shifts in emission sectors and emission species that contribute to premature mortality may help to guide improvements to air quality in the contiguous United States.


  
Archaeological assessment reveals Earth's early transformation through land use 期刊论文
SCIENCE, 2019, 365 (6456) : 897-+
作者:  Stephens, Lucas;  Fuller, Dorian;  Boivin, Nicole;  Rick, Torben;  Gauthier, Nicolas;  Kay, Andrea;  Marwick, Ben;  Armstrong, Chelsey Geralda Denise;  Barton, C. Michael;  Denham, Tim;  Douglass, Kristina;  Driver, Jonathan;  Janz, Lisa;  Roberts, Patrick;  Rogers, J. Daniel;  Thakar, Heather;  Altaweel, Mark;  Johnson, Amber L.;  Sampietro Vattuone, Maria Marta;  Aldenderfer, Mark;  Archila, Sonia;  Artioli, Gilberto;  Bale, Martin T.;  Beach, Timothy;  Borrell, Ferran;  Braje, Todd;  Buckland, Philip I.;  Jimenez Cano, Nayeli Guadalupe;  Capriles, Jose M.;  Diez Castillo, Agustin;  Cilingiroglu, Ciler;  Cleary, Michelle Negus;  Conolly, James;  Coutros, Peter R.;  Covey, R. Alan;  Cremaschi, Mauro;  Crowther, Alison;  Der, Lindsay;  di Lernia, Savino;  Doershuk, John F.;  Doolittle, William E.;  Edwards, Kevin J.;  Erlandson, Jon M.;  Evans, Damian;  Fairbairn, Andrew;  Faulkner, Patrick;  Feinman, Gary;  Fernandes, Ricardo;  Fitzpatrick, Scott M.;  Fyfe, Ralph;  Garcea, Elena;  Goldstein, Steve;  Goodman, Reed Charles;  Guedes, Jade Dalpoim;  Herrmann, Jason;  Hiscock, Peter;  Hommel, Peter;  Horsburgh, K. Ann;  Hritz, Carrie;  Ives, John W.;  Junno, Aripekka;  Kahn, Jennifer G.;  Kaufman, Brett;  Kearns, Catherine;  Kidder, Tristram R.;  Lanoe, Francois;  Lawrence, Dan;  Lee, Gyoung-Ah;  Levin, Maureece J.;  Lindskoug, Henrik B.;  Antonio Lopez-Saez, Jose;  Macrae, Scott;  Marchant, Rob;  Marston, John M.;  McClure, Sarah;  Mccoy, Mark D.;  Miller, Alicia Ventresca;  Morrison, Michael;  Matuzeviciute, Giedre Motuzaite;  Mueller, Johannes;  Nayak, Ayushi;  Noerwidi, Sofwan;  Peres, Tanya M.;  Peterson, Christian E.;  Proctor, Lucas;  Randall, Asa R.;  Renette, Steve;  Schug, Gwen Robbins;  Ryzewski, Krysta;  Saini, Rakesh;  Scheinsohn, Vivian;  Schmidt, Peter;  Sebillaud, Pauline;  Seitsonen, Oula;  Simpson, Ian A.;  Soltysiak, Arkadiusz;  Speakman, Robert J.;  Spengler, Robert N.;  Steffen, Martina L.;  Storozum, Michael J.;  Strickland, Keir M.;  Thompson, Jessica;  Thurston, T. L.;  Ulm, Sean;  Ustunkaya, M. Cemre;  Welker, Martin H.;  West, Catherine;  Williams, Patrick Ryan;  Wright, David K.;  Wright, Nathan;  Zahir, Muhammad;  Zerboni, Andrea;  Beaudoin, Ella;  Garcia, Santiago Munevar;  Powell, Jeremy;  Thornton, Alexa;  Kaplan, Jed O.;  Gaillard, Marie-Jose;  Goldewijk, Kees Klein;  Ellis, Erle
收藏  |  浏览/下载:56/0  |  提交时间:2019/11/27
ATP-dependent force generation and membrane scission by ESCRT-III and Vps4 期刊论文
SCIENCE, 2018, 362 (6421) : 1423-+
作者:  Schoneberg, Johannes;  Pavlin, Mark Remec;  Yan, Shannon;  Righini, Maurizio;  Lee, Il-Hyung;  Carlson, Lars-Anders;  Bahrami, Amir Houshang;  Goldman, Daniel H.;  Ren, Xuefeng;  Hummer, Gerhard;  Bustamante, Carlos;  Hurley, James H.
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics 期刊论文
SCIENCE, 2018, 359 (6372) : 191-+
作者:  Cowell, Annie N.;  Istvan, Eva S.;  Lukens, Amanda K.;  Gomez-Lorenzo, Maria G.;  Vanaerschot, Manu;  Sakata-Kato, Tomoyo;  Flannery, Erika L.;  Magistrado, Pamela;  Owen, Edward;  Abraham, Matthew;  LaMonte, Gregory;  Painter, Heather J.;  Williams, Roy M.;  Franco, Virginia;  Linares, Maria;  Arriaga, Ignacio;  Bopp, Selina;  Corey, Victoria C.;  Gnadig, Nina F.;  Coburn-Flynn, Olivia;  Reimer, Christin;  Gupta, Purva;  Murithi, James M.;  Moura, Pedro A.;  Fuchs, Olivia;  Sasaki, Erika;  Kim, Sang W.;  Teng, Christine H.;  Wang, Lawrence T.;  Akidil, Asli;  Adjalley, Sophie;  Willis, Paul A.;  Siegel, Dionicio;  Tanaseichuk, Olga;  Zhong, Yang;  Zhou, Yingyao;  Llinas, Manuel;  Ottilie, Sabine;  Gamo, Francisco-Javier;  Lee, Marcus C. S.;  Goldberg, Daniel E.;  Fidock, David A.;  Wirth, Dyann F.;  Winzeler, Elizabeth A.
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/27
Observations of MeV electrons in Jupiter's innermost radiation belts and polar regions by the Juno radiation monitoring investigation: Perijoves 1 and 3 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2017, 44 (10)
作者:  Becker, Heidi N.;  Santos-Costa, Daniel;  Jorgensen, John L.;  Denver, Troelz;  Adriani, Alberto;  Mura, Alessandro;  Connerney, John E. P.;  Bolton, Scott J.;  Levin, Steven M.;  Thorne, Richard M.;  Alexander, James W.;  Adumitroaie, Virgil;  Manor-Chapman, Emily A.;  Daubar, Ingrid J.;  Lee, Clifford;  Benn, Mathias;  Sushkova, Julia;  Cicchetti, Andrea;  Noschese, Raffaella
收藏  |  浏览/下载:8/0  |  提交时间:2019/04/09