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DNA-repair enzyme turns to translation 期刊论文
NATURE, 2020, 579 (7798) : 198-199
作者:  Bian, Zhilei;  Gong, Yandong;  Huang, Tao;  Lee, Christopher Z. W.;  Bian, Lihong;  Bai, Zhijie;  Shi, Hui;  Zeng, Yang;  Liu, Chen;  He, Jian;  Zhou, Jie;  Li, Xianlong;  Li, Zongcheng;  Ni, Yanli;  Ma, Chunyu;  Cui, Lei;  Zhang, Rui;  Chan, Jerry K. Y.;  Ng, Lai Guan;  Lan, Yu;  Ginhoux, Florent;  Liu, Bing
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/03

A key DNA-repair enzyme has a surprising role during the early steps in the assembly of ribosomes - the molecular machines that translate the genetic code into protein.


  
Tertiary lymphoid structures improve immunotherapy and survival in melanoma (vol 577, pg 561, 2020) 期刊论文
NATURE, 2020
作者:  Tang, Yanhao;  Li, Lizhong;  Li, Tingxin;  Xu, Yang;  Liu, Song;  Barmak, Katayun;  Watanabe, Kenji;  Taniguchi, Takashi;  MacDonald, Allan H.;  Shan, Jie;  Mak, Kin Fai
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/03

An Amendment to this paper has been published and can be accessed via a link at the top of the paper.


  
Mott and generalized Wigner crystal states in WSe2/WS2 moire superlattices 期刊论文
NATURE, 2020, 579 (7799) : 359-+
作者:  Yuan, Jie;  Chang, Si-Yuan;  Yin, Shi-Gang;  Liu, Zhi-Yang;  Cheng, Xiu;  Liu, Xi-Juan;  Jiang, Qiang;  Gao, Ge;  Lin, De-Ying;  Kang, Xin-Lei;  Ye, Shi-Wei;  Chen, Zheng;  Yin, Jiang-An;  Hao, Pei;  Jiang, Lubin;  Cai, Shi-Qing
收藏  |  浏览/下载:50/0  |  提交时间:2020/07/03

Strongly correlated insulating Mott and generalized Wigner phases are detected in WSe2/WS2 moire superlattices, and their electrical properties and excited spin states are studied using an optical technique.


Moire superlattices can be used to engineer strongly correlated electronic states in two-dimensional van der Waals heterostructures, as recently demonstrated in the correlated insulating and superconducting states observed in magic-angle twisted-bilayer graphene and ABC trilayer graphene/boron nitride moire superlattices(1-4). Transition metal dichalcogenide moire heterostructures provide another model system for the study of correlated quantum phenomena(5) because of their strong light-matter interactions and large spin-orbit coupling. However, experimental observation of correlated insulating states in this system is challenging with traditional transport techniques. Here we report the optical detection of strongly correlated phases in semiconducting WSe2/WS2 moire superlattices. We use a sensitive optical detection technique and reveal a Mott insulator state at one hole per superlattice site and surprising insulating phases at 1/3 and 2/3 filling of the superlattice, which we assign to generalized Wigner crystallization on the underlying lattice(6-11). Furthermore, the spin-valley optical selection rules(12-14) of transition metal dichalcogenide heterostructures allow us to optically create and investigate low-energy excited spin states in the Mott insulator. We measure a very long spin relaxation lifetime of many microseconds in the Mott insulating state, orders of magnitude longer than that of charge excitations. Our studies highlight the value of using moire superlattices beyond graphene to explore correlated physics.


  
A self-activating orphan receptor 期刊论文
NATURE, 2020, 579 (7797) : 35-35
作者:  Wang, Lin;  Wu, Juehui;  Li, Jun;  Yang, Hua;  Tang, Tianqi;  Liang, Haijiao;  Zuo, Mianyong;  Wang, Jie;  Liu, Haipeng;  Liu, Feng;  Chen, Jianxia;  Liu, Zhonghua;  Wang, Yang;  Peng, Cheng;  Wu, Xiangyang;  Zheng, Ruijuan;  Huang, Xiaochen;  Ran, Yajun;  Rao, Zihe;  Ge, Baoxue
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

The first 3D structure of a full-length G-protein-coupled receptor whose natural activator is unknown has been determined, providing insights into an unusual mode of activation and a basis for discovering therapeutics.


  
China takes centre stage in global biodiversity push 期刊论文
NATURE, 2020, 578 (7795) : 345-346
作者:  Wang, Lin;  Wu, Juehui;  Li, Jun;  Yang, Hua;  Tang, Tianqi;  Liang, Haijiao;  Zuo, Mianyong;  Wang, Jie;  Liu, Haipeng;  Liu, Feng;  Chen, Jianxia;  Liu, Zhonghua;  Wang, Yang;  Peng, Cheng;  Wu, Xiangyang;  Zheng, Ruijuan;  Huang, Xiaochen;  Ran, Yajun;  Rao, Zihe;  Ge, Baoxue
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/03

A major United Nations summit could see China push for ambitious targets and spotlights the country'  s own conservation efforts.


A major United Nations summit could see China push for ambitious targets and spotlights the country'  s own conservation efforts.


  
High thermoelectric performance in low-cost SnS0.91Se0.09 crystals 期刊论文
SCIENCE, 2019, 365 (6460) : 1418-+
作者:  He, Wenke;  Wang, Dongyang;  Wu, Haijun;  Xiao, Yu;  Zhang, Yang;  He, Dongsheng;  Feng, Yue;  Hao, Yu-Jie;  Dong, Jin-Feng;  Chetty, Raju;  Hao, Lijie;  Chen, Dongfeng;  Qin, Jianfei;  Yang, Qiang;  Li, Xin;  Song, Jian-Ming;  Zhu, Yingcai;  Xu, Wei;  Niu, Changlei;  Li, Xin;  Wang, Guangtao;  Liu, Chang;  Ohta, Michibiro;  Pennycook, Stephen J.;  He, Jiaqing;  Li, Jing-Feng;  Zhao, Li-Dong
收藏  |  浏览/下载:22/0  |  提交时间:2019/11/27
Generation of multicomponent atomic Schrodinger cat states of up to 20 qubits 期刊论文
SCIENCE, 2019, 365 (6453) : 574-577
作者:  Song, Chao;  Xu, Kai;  Li, Hekang;  Zhang, Yu-Ran;  Zhang, Xu;  Liu, Wuxin;  Guo, Qiujiang;  Wang, Zhen;  Ren, Wenhui;  Hao, Jie;  Feng, Hui;  Fan, Heng;  Zheng, Dongning;  Wang, Da-Wei;  Wang, H.;  Zhu, Shi-Yao
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
Resetting histone modifications during human parental-to-zygotic transition 期刊论文
SCIENCE, 2019, 365 (6451) : 353-+
作者:  Xia, Weikun;  Xu, Jiawei;  Yu, Guang;  Yao, Guidong;  Xu, Kai;  Ma, Xueshan;  Zhang, Nan;  Liu, Bofeng;  Li, Tong;  Lin, Zili;  Chen, Xia;  Li, Lijia;  Wang, Qiujun;  Shi, Dayuan;  Shi, Senlin;  Zhang, Yile;  Song, Wenyan;  Jin, Haixia;  Hu, Linli;  Bu, Zhiqin;  Wang, Yang;  Na, Jie;  Xie, Wei;  Sun, Ying-Pu
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits 期刊论文
SCIENCE, 2019, 364 (6446) : 1152-+
作者:  Chen, Lei;  Qin, Qiang;  Jiang, Yu;  Wang, Kun;  Lin, Zeshan;  Li, Zhipeng;  Bibi, Faysal;  Yang, Yongzhi;  Wang, Jinhuan;  Nie, Wenhui;  Su, Weiting;  Liu, Guichun;  Li, Qiye;  Fu, Weiwei;  Pan, Xiangyu;  Liu, Chang;  Yang, Jie;  Zhang, Chenzhou;  Yin, Yuan;  Wang, Yu;  Zhao, Yue;  Zhang, Chen;  Wang, Zhongkai;  Qin, Yanli;  Liu, Wei;  Wang, Bao;  Ren, Yandong;  Zhang, Ru;  Zeng, Yan;  da Fonseca, Rute R.;  Wei, Bin;  Li, Ran;  Wan, Wenting;  Zhao, Ruoping;  Zhu, Wenbo;  Wang, Yutao;  Duan, Shengchang;  Gao, Yun;  Zhang, Yong E.;  Chen, Chunyan;  Hvilsom, Christina;  Epps, Clinton W.;  Chemnick, Leona G.;  Doug, Yang;  Mirarab, Siavash;  Siegismund, Hans Redlef;  Ryder, Oliver A.;  Gilbert, M. Thomas P.;  Lewin, Harris A.;  Zhang, Guojie;  Heller, Rasmus;  Wang, Wen
收藏  |  浏览/下载:17/0  |  提交时间:2019/11/27
Long-term functional maintenance of primary human hepatocytes in vitro 期刊论文
SCIENCE, 2019, 364 (6438) : 399-+
作者:  Xiang, Chengang;  Du, Yuanyuan;  Meng, Gaofan;  Yi, Liew Soon;  Sun, Shicheng;  Song, Nan;  Zhang, Xiaonan;  Xiao, Yiwei;  Wang, Jie;  Yi, Zhigang;  Liu, Yifang;  Xie, Bingqing;  Wu, Min;  Shu, Jun;  Sun, Da;  Jia, Jun;  Liang, Zhen;  Sun, Dong;  Huang, Yanxiang;  Shi, Yan;  Xu, Jun;  Lu, Fengmin;  Li, Cheng;  Xiang, Kuanhui;  Yuan, Zhenghong;  Lu, Shichun;  Deng, Hongkui
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27