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Chemical characterization of secondary organic aerosol at a rural site in the southeastern US: insights from simultaneous high-resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS) and FIGAERO chemical ionization mass spectrometer (CIMS) measurements 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (14) : 8421-8440
作者:  Chen, Yunle;  Takeuchi, Masayuki;  Nah, Theodora;  Xu, Lu;  Canagaratna, Manjula R.;  Stark, Harald;  Baumann, Karsten;  Canonaco, Francesco;  Prevot, Andre S. H.;  Huey, L. Gregory;  Weber, Rodney J.;  Ng, Nga L.
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/21
Southern Ocean carbon sink enhanced by sea-ice feedbacks at the Antarctic Cold Reversal 期刊论文
NATURE GEOSCIENCE, 2020, 13 (7) : 489-+
作者:  Fogwill, C. J.;  Turney, C. S. M.;  Menviel, L.;  Baker, A.;  Weber, M. E.;  Ellis, B.;  Thomas, Z. A.;  Golledge, N. R.;  Etheridge, D.;  Rubino, M.;  Thornton, D. P.;  van Ommen, T. D.;  Moy, A. D.;  Curran, M. A. J.;  Davies, S.;  Bird, M., I;  Munksgaard, N. C.;  Rootes, C. M.;  Millman, H.;  Vohra, J.;  Rivera, A.;  Mackintosh, A.;  Pike, J.;  Hall, I. R.;  Bagshaw, E. A.;  Rainsley, E.;  Bronk-Ramsey, C.;  Montenari, M.;  Cage, A. G.;  Harris, M. R. P.;  Jones, R.;  Power, A.;  Love, J.;  Young, J.;  Weyrich, L. S.;  Cooper, A.
收藏  |  浏览/下载:14/0  |  提交时间:2020/06/29
The seismicity of Mars 期刊论文
NATURE GEOSCIENCE, 2020, 13 (3) : 205-+
作者:  Giardini, D.;  Lognonne, P.;  Banerdt, W. B.;  Pike, W. T.;  Christensen, U.;  Ceylan, S.;  Clinton, J. F.;  van Driel, M.;  Staehler, S. C.;  Boese, M.;  Garcia, R. F.;  Khan, A.;  Panning, M.;  Perrin, C.;  Banfield, D.;  Beucler, E.;  Charalambous, C.;  Euchner, F.;  Horleston, A.;  Jacob, A.;  Kawamura, T.;  Kedar, S.;  Mainsant, G.;  Scholz, J. -R.;  Smrekar, S. E.;  Spiga, A.;  Agard, C.;  Antonangeli, D.;  Barkaoui, S.;  Barrett, E.;  Combes, P.;  Conejero, V.;  Daubar, I.;  Drilleau, M.;  Ferrier, C.;  Gabsi, T.;  Gudkova, T.;  Hurst, K.;  Karakostas, F.;  King, S.;  Knapmeyer, M.;  Knapmeyer-Endrun, B.;  Llorca-Cejudo, R.;  Lucas, A.;  Luno, L.;  Margerin, L.;  McClean, J. B.;  Mimoun, D.;  Murdoch, N.;  Nimmo, F.;  Nonon, M.;  Pardo, C.;  Rivoldini, A.;  Manfredi, J. A. Rodriguez;  Samuel, H.;  Schimmel, M.;  Stott, A. E.;  Stutzmann, E.;  Teanby, N.;  Warren, T.;  Weber, R. C.;  Wieczorek, M.;  Yana, C.
收藏  |  浏览/下载:11/0  |  提交时间:2020/05/13
Constraints on the shallow elastic and anelastic structure of Mars from InSight seismic data 期刊论文
NATURE GEOSCIENCE, 2020, 13 (3) : 213-+
作者:  Lognonne, P.;  Banerdt, W. B.;  Pike, W. T.;  Giardini, D.;  Christensen, U.;  Garcia, R. F.;  Kawamura, T.;  Kedar, S.;  Knapmeyer-Endrun, B.;  Margerin, L.;  Nimmo, F.;  Panning, M.;  Tauzin, B.;  Scholz, J. -R.;  Antonangeli, D.;  Barkaoui, S.;  Beucler, E.;  Bissig, F.;  Brinkman, N.;  Calvet, M.;  Ceylan, S.;  Charalambous, C.;  Davis, P.;  Van Driel, M.;  Drilleau, M.;  Fayon, L.;  Joshi, R.;  Kenda, B.;  Khan, A.;  Knapmeyer, M.;  Lekic, V.;  McClean, J.;  Mimoun, D.;  Murdoch, N.;  Pan, L.;  Perrin, C.;  Pinot, B.;  Pou, L.;  Menina, S.;  Rodriguez, S.;  Schmelzbach, C.;  Schmerr, N.;  Sollberger, D.;  Spiga, A.;  Staehler, S.;  Stott, A.;  Stutzmann, E.;  Tharimena, S.;  Widmer-Schnidrig, R.;  Andersson, F.;  Ansan, V.;  Beghein, C.;  Boese, M.;  Bozdag, E.;  Clinton, J.;  Daubar, I.;  Delage, P.;  Fuji, N.;  Golombek, M.;  Grott, M.;  Horleston, A.;  Hurst, K.;  Irving, J.;  Jacob, A.;  Knollenberg, J.;  Krasner, S.;  Krause, C.;  Lorenz, R.;  Michaut, C.;  Myhill, R.;  Nissen-Meyer, T.;  Ten Pierick, J.;  Plesa, A. -C.;  Quantin-Nataf, C.;  Robertsson, J.;  Rochas, L.;  Schimmel, M.;  Smrekar, S.;  Spohn, T.;  Teanby, N.;  Tromp, J.;  Vallade, J.;  Verdier, N.;  Vrettos, C.;  Weber, R.;  Banfield, D.;  Barrett, E.;  Bierwirth, M.;  Calcutt, S.;  Compaire, N.;  Johnson, C. L.;  Mance, D.;  Euchner, F.;  Kerjean, L.;  Mainsant, G.;  Mocquet, A.;  Rodriguez Manfredi, J. A.;  Pont, G.;  Laudet, P.;  Nebut, T.;  De Raucourt, S.;  Robert, O.;  Russell, C. T.;  Sylvestre-Baron, A.;  Tillier, S.;  Warren, T.;  Wieczorek, M.;  Yana, C.;  Zweifel, P.
收藏  |  浏览/下载:20/0  |  提交时间:2020/05/13
Synthesis of rare sugar isomers through site-selective epimerization 期刊论文
NATURE, 2020: 403-+
作者:  Jackson, Hartland W.;  Fischer, Jana R.;  Zanotelli, Vito R. T.;  Ali, H. Raza;  Mechera, Robert;  Soysal, Savas D.;  Moch, Holger;  Muenst, Simone;  Varga, Zsuzsanna;  Weber, Walter P.;  Bodenmiller, Bernd
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/03

Glycans have diverse physiological functions, ranging from energy storage and structural integrity to cell signalling and the regulation of intracellular processes(1). Although biomass-derived carbohydrates (such as d-glucose, d-xylose and d-galactose) are extracted on commercial scales, and serve as renewable chemical feedstocks and building blocks(2,3), there are hundreds of distinct monosaccharides that typically cannot be isolated from their natural sources and must instead be prepared through multistep chemical or enzymatic syntheses(4,5). These '  rare'  sugars feature prominently in bioactive natural products and pharmaceuticals, including antiviral, antibacterial, anticancer and cardiac drugs(6,7). Here we report the preparation of rare sugar isomers directly from biomass carbohydrates through site-selective epimerization reactions. Mechanistic studies establish that these reactions proceed under kinetic control, through sequential steps of hydrogen-atom abstraction and hydrogen-atom donation mediated by two distinct catalysts. This synthetic strategy provides concise and potentially extensive access to this valuable class of natural compounds.


Various rare sugars that cannot be isolated from natural sources are synthesized using light-driven epimerization, a process which may find application in other synthetic scenarios.


  
Lactose drives Enterococcus expansion to promote graft-versus-host disease 期刊论文
SCIENCE, 2019, 366 (6469) : 1143-+
作者:  Stein-Thoeringer, C. K.;  Nichols, K. B.;  Lazrak, A.;  Docampo, M. D.;  Slingerland, A. E.;  Slingerland, J. B.;  Clurman, A. G.;  Armijo, G.;  Gomes, A. L. C.;  Shono, Y.;  Staffas, A.;  da Silva, M. Burgos;  Devlin, S. M.;  Markey, K. A.;  Bajic, D.;  Pinedo, R.;  Tsakmaklis, A.;  Littmann, E. R.;  Pastore, A.;  Taur, Y.;  Monette, S.;  Arcila, M. E.;  Pickard, A. J.;  Maloy, M.;  Wright, R. J.;  Amoretti, L. A.;  Fontana, E.;  Pham, D.;  Jamal, M. A.;  Weber, D.;  Sung, A. D.;  Hashimoto, D.;  Scheid, C.;  Xavier, J. B.;  Messina, J. A.;  Romero, K.;  Lew, M.;  Bush, A.;  Bohannon, L.;  Hayasaka, K.;  Hasegawa, Y.;  Vehreschild, M. J. G. T.;  Cross, J. R.;  Ponce, D. M.;  Perales, M. A.;  Giralt, S. A.;  Jenq, R. R.;  Teshima, T.;  Holler, E.;  Chao, N. J.;  Pamer, E. G.;  Peled, J. U.;  van den Brink, M. R. M.
收藏  |  浏览/下载:14/0  |  提交时间:2020/02/17
Land cover and its transformation in the backward trajectory footprint region of the Amazon Tall Tower Observatory 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (13) : 8425-8470
作者:  Poehlker, Christopher;  Walter, David;  Paulsen, Hauke;  Koenemann, Tobias;  Rodriguez-Caballero, Emilio;  Moran-Zuloaga, Daniel;  Brito, Joel;  Carbone, Samara;  Degrendele, Celine;  Despres, Viviane R.;  Ditas, Florian;  Holanda, Bruna A.;  Kaiser, Johannes W.;  Lammel, Gerhard;  Lavric, Jost V.;  Ming, Jing;  Pickersgill, Daniel;  Poehlker, Mira L.;  Prass, Maria;  Loebs, Nina;  Saturno, Jorge;  Soergel, Matthias;  Wang, Qiaoqiao;  Weber, Bettina;  Wolff, Stefan;  Artaxo, Paulo;  Poeschl, Ulrich;  Andreae, Meinrat O.
收藏  |  浏览/下载:15/0  |  提交时间:2019/11/27
Shallow seismic activity and young thrust faults on the Moon 期刊论文
NATURE GEOSCIENCE, 2019, 12 (6) : 411-+
作者:  Watters, Thomas R.;  Weber, Renee C.;  Collins, Geoffrey C.;  Howley, Ian J.;  Schmerr, Nicholas C.;  Johnson, Catherine L.
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/26
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity (vol 483, pg 603, 2012) 期刊论文
NATURE, 2019, 565 (7738) : E5-E6
作者:  Barretina, Jordi;  Caponigro, Giordano;  Stransky, Nicolas;  Venkatesan, Kavitha;  Margolin, Adam A.;  Kim, Sungjoon;  Wilson, Christopher J.;  Lehar, Joseph;  Kryukov, Gregory V.;  Sonkin, Dmitriy;  Reddy, Anupama;  Liu, Manway;  Murray, Lauren;  Berger, Michael F.;  Monahan, John E.;  Morais, Paula;  Meltzer, Jodi;  Korejwa, Adam;  Jane-Valbuena, Judit;  Mapa, Felipa A.;  Thibault, Joseph;  Bric-Furlong, Eva;  Raman, Pichai;  Shipway, Aaron;  Engels, Ingo H.;  Cheng, Jill;  Yu, Guoying K.;  Yu, Jianjun;  Aspesi, Peter, Jr.;  de Silva, Melanie;  Jagtap, Kalpana;  Jones, Michael D.;  Wang, Li;  Hatton, Charles;  Palescandolo, Emanuele;  Gupta, Supriya;  Mahan, Scott;  Sougnez, Carrie;  Onofrio, Robert C.;  Liefeld, Ted;  MacConaill, Laura;  Winckler, Wendy;  Reich, Michael;  Li, Nanxin;  Mesirov, Jill P.;  Gabriel, Stacey B.;  Getz, Gad;  Ardlie, Kristin;  Chan, Vivien;  Myer, Vic E.;  Weber, Barbara L.;  Porter, Jeff;  Warmuth, Markus;  Finan, Peter;  Harris, Jennifer L.;  Meyerson, Matthew;  Golub, Todd R.;  Morrissey, Michael P.;  Sellers, William R.;  Schlegel, Robert;  Garraway, Levi A.
收藏  |  浏览/下载:22/0  |  提交时间:2019/11/27
Chemical feedbacks weaken the wintertime response of particulate sulfate and nitrate to emissions reductions over the eastern United States 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (32) : 8110-8115
作者:  Shah, Viral;  Jaegle, Lyatt;  Thornton, Joel A.;  Lopez-Hilfiker, Felipe D.;  Lee, Ben H.;  Schroder, Jason C.;  Campuzano-Jost, Pedro;  Jimenez, Jose L.;  Guo, Hongyu;  Sullivan, Amy P.;  Weber, Rodney J.;  Green, Jaime R.;  Fiddler, Marc N.;  Bililign, Solomon;  Campos, Teresa L.;  Stell, Meghan;  Weinheimer, Andrew J.;  Montzka, Denise D.;  Brown, Steven S.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
sulfate  nitrate  winter  anthropogenic emissions  PM2.5