GSTDTAP

浏览/检索结果: 共140条,第1-10条 帮助

限定条件        
已选(0)清除 条数/页:   排序方式:
Bin-Emulating Hail Melting in Three-Moment Bulk Microphysics 期刊论文
Journal of the Atmospheric Sciences, 2020
作者:  Mansell, Edward R.;  Dawson II, Daniel T.;  Straka, Jerry M.
收藏  |  浏览/下载:5/0  |  提交时间:2020/10/12
Homogenization of the terrestrial water cycle 期刊论文
Nature, 2020
作者:  Delphis F. Levia;  Irena F. Creed;  David M. Hannah;  Kazuki Nanko;  Elizabeth W. Boyer;  Darryl E. Carlyle-Moses;  Nick van de Giesen;  Domenico Grasso;  Andrew J. Guswa;  Janice E. Hudson;  Sean A. Hudson;  Shin’;  ichi Iida;  Robert B. Jackson;  Gabriel G. Katul;  Tomo’;  omi Kumagai;  Pilar Llorens;  Flavio Lopes Ribeiro;  Diane E. Pataki;  Catherine A. Peters;  Daniel Sanchez Carretero;  John S. Selker;  Doerthe Tetzlaff;  Maciej Zalewski;  Michael Bruen
收藏  |  浏览/下载:13/0  |  提交时间:2020/09/30
Composite In Situ Microphysical Analysis of All Spiral Vertical Profiles Executed within BAMEX and PECAN Mesoscale Convective Systems 期刊论文
Journal of the Atmospheric Sciences, 2020
作者:  Stechman, Daniel M.;  McFarquhar, Greg M.;  Rauber, Robert M.;  Jewett, Brian F.;  Black, Robert A.
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/09
A remnant planetary core in the hot-Neptune desert 期刊论文
NATURE, 2020, 583 (7814) : 39-+
作者:  David J. Armstrong;  Thé;  o A. Lopez;  Vardan Adibekyan;  Richard A. Booth;  Edward M. Bryant;  Karen A. Collins;  Magali Deleuil;  Alexandre Emsenhuber;  Chelsea X. Huang;  George W. King;  Jorge Lillo-Box;  Jack J. Lissauer;  Elisabeth Matthews;  Olivier Mousis;  Louise D. Nielsen;  Hugh Osborn;  Jon Otegi;  Nuno C. Santos;  ;  rgio G. Sousa;  Keivan G. Stassun;  Dimitri Veras;  Carl Ziegler;  Jack S. Acton;  Jose M. Almenara;  David R. Anderson;  David Barrado;  Susana C. C. Barros;  Daniel Bayliss;  Claudia Belardi;  Francois Bouchy;  ;  sar Briceñ;  o;  Matteo Brogi;  David J. A. Brown;  Matthew R. Burleigh;  Sarah L. Casewell;  Alexander Chaushev;  David R. Ciardi;  Kevin I. Collins;  Knicole D. Coló;  n;  Benjamin F. Cooke;  Ian J. M. Crossfield;  Rodrigo F. Dí;  az;  Elisa Delgado Mena;  Olivier D. S. Demangeon;  Caroline Dorn;  Xavier Dumusque;  Philipp Eigmü;  ller;  Michael Fausnaugh;  Pedro Figueira;  Tianjun Gan;  Siddharth Gandhi;  Samuel Gill;  Erica J. Gonzales;  Michael R. Goad;  Maximilian N. Gü;  nther;  Ravit Helled;  Saeed Hojjatpanah;  Steve B. Howell;  James Jackman;  James S. Jenkins;  Jon M. Jenkins;  Eric L. N. Jensen;  Grant M. Kennedy;  David W. Latham;  Nicholas Law;  Monika Lendl;  Michael Lozovsky;  Andrew W. Mann;  Maximiliano Moyano;  James McCormac;  Farzana Meru;  Christoph Mordasini;  Ares Osborn;  Don Pollacco;  Didier Queloz;  Liam Raynard;  George R. Ricker;  Pamela Rowden;  Alexandre Santerne;  Joshua E. Schlieder;  Sara Seager;  Lizhou Sha;  Thiam-Guan Tan;  Rosanna H. Tilbrook;  Eric Ting;  Sté;  phane Udry;  Roland Vanderspek;  Christopher A. Watson;  Richard G. West;  Paul A. Wilson;  Joshua N. Winn;  Peter Wheatley;  Jesus Noel Villasenor;  Jose I. Vines;  Zhuchang Zhan
收藏  |  浏览/下载:20/0  |  提交时间:2020/07/06

The interiors of giant planets remain poorly understood. Even for the planets in the Solar System, difficulties in observation lead to large uncertainties in the properties of planetary cores. Exoplanets that have undergone rare evolutionary processes provide a route to understanding planetary interiors. Planets found in and near the typically barren hot-Neptune '  desert'  (1,2)(a region in mass-radius space that contains few planets) have proved to be particularly valuable in this regard. These planets include HD149026b(3), which is thought to have an unusually massive core, and recent discoveries such as LTT9779b(4)and NGTS-4b(5), on which photoevaporation has removed a substantial part of their outer atmospheres. Here we report observations of the planet TOI-849b, which has a radius smaller than Neptune'  s but an anomalously large mass of39.1-2.6+2.7Earth masses and a density of5.2-0.8+0.7grams per cubic centimetre, similar to Earth'  s. Interior-structure models suggest that any gaseous envelope of pure hydrogen and helium consists of no more than3.9-0.9+0.8 per cent of the total planetary mass. The planet could have been a gas giant before undergoing extreme mass loss via thermal self-disruption or giant planet collisions, or it could have avoided substantial gas accretion, perhaps through gap opening or late formation(6). Although photoevaporation rates cannot account for the mass loss required to reduce a Jupiter-like gas giant, they can remove a small (a few Earth masses) hydrogen and helium envelope on timescales of several billion years, implying that any remaining atmosphere on TOI-849b is likely to be enriched by water or other volatiles from the planetary interior. We conclude that TOI-849b is the remnant core of a giant planet.


Observations of TOI-849b reveal a radius smaller than Neptune'  s but a large mass of about 40 Earth masses, indicating that the planet is the remnant core of a gas giant.


  
Rapidly-migrating and internally-generated knickpoints can control submarine channel evolution 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Heijnen, Maarten S.;  Clare, Michael A.;  Cartigny, Matthieu J. B.;  Talling, Peter J.;  Hage, Sophie;  Lintern, D. Gwyn;  Stacey, Cooper;  Parsons, Daniel R.;  Simmons, Stephen M.;  Chen, Ye;  Sumner, Esther J.;  Dix, Justin K.;  Clarke, John E. Hughes
收藏  |  浏览/下载:13/0  |  提交时间:2020/06/22
Geometry and evolution of the ecological niche in plant-associated microbes 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Chaloner, Thomas M.;  Gurr, Sarah J.;  Bebber, Daniel P.
收藏  |  浏览/下载:7/0  |  提交时间:2020/06/16
Rapid range shifts and megafaunal extinctions associated with late Pleistocene climate change 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Seersholm, Frederik V.;  Werndly, Daniel J.;  Grealy, Alicia;  Johnson, Taryn;  Keenan Early, Erin M.;  Lundelius, Ernest L.;  Winsborough, Barbara;  Farr, Grayal Earle;  Toomey, Rickard;  Hansen, Anders J.;  Shapiro, Beth;  Waters, Michael R.;  McDonald, Gregory;  Linderholm, Anna;  Stafford, Thomas W., Jr.;  Bunce, Michael
收藏  |  浏览/下载:8/0  |  提交时间:2020/06/09
Stable Boundary Layer Regimes in Single-Column Models 期刊论文
Journal of the Atmospheric Sciences, 2020
作者:  Felipe D. Costa;  Otávio C. Acevedo;  Luiz E. Medeiros;  Rafael Maroneze;  Franciano S. Puhales;  Arlindo D. Carvalho Jr.;  Luis F. Camponogara;  Daniel M. dos Santos;  Luca Mortarini
收藏  |  浏览/下载:6/0  |  提交时间:2020/05/25
WHAT SCIENTISTS WANT TO KNOW ABOUT THE CORONAVIRUS OUTBREAK 期刊论文
NATURE, 2020, 577 (7792) : 605-607
作者:  Shade, Kai-Ting C.;  Conroy, Michelle E.;  Washburn, Nathaniel;  Kitaoka, Maya;  Huynh, Daniel J.;  Laprise, Emma;  Patil, Sarita U.;  Shreffler, Wayne G.;  Anthony, Robert M.
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/03
Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease 期刊论文
NATURE, 2020, 577 (7788) : 103-+
作者:  Lalaoui, Najoua;  Boyden, Steven E.;  Oda, Hirotsugu;  Wood, Geryl M.;  Stone, Deborah L.;  Chau, Diep;  Liu, Lin;  Stoffels, Monique;  Kratina, Tobias;  Lawlor, Kate E.;  Zaal, Kristien J. M.;  Hoffmann, Patrycja M.;  Etemadi, Nima;  Shield-Artin, Kristy;  Biben, Christine;  Tsai, Wanxia Li;  Blake, Mary D.;  Kuehn, Hye Sun;  Yang, Dan;  Anderton, Holly;  Silke, Natasha;  Wachsmuth, Laurens;  Zheng, Lixin;  Moura, Natalia Sampaio;  Beck, David B.;  Gutierrez-Cruz, Gustavo;  Ombrello, Amanda K.;  Pinto-Patarroyo, Gineth P.;  Kueh, Andrew J.;  Herold, Marco J.;  Hall, Cathrine;  Wang, Hongying;  Chae, Jae Jin;  Dmitrieva, Natalia I.;  McKenzie, Mark;  Light, Amanda;  Barham, Beverly K.;  Jones, Anne;  Romeo, Tina M.;  Zhou, Qing;  Aksentijevich, Ivona;  Mullikin, James C.;  Gross, Andrew J.;  Shum, Anthony K.;  Hawkins, Edwin D.;  Masters, Seth L.;  Lenardo, Michael J.;  Boehm, Manfred;  Rosenzweig, Sergio D.;  Pasparakis, Manolis;  Voss, Anne K.;  Gadina, Massimo;  Kastner, Daniel L.;  Silke, John
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/03

RIPK1 is a key regulator of innate immune signalling pathways. To ensure an optimal inflammatory response, RIPK1 is regulated post-translationally by well-characterized ubiquitylation and phosphorylation events, as well as by caspase-8-mediated cleavage1-7. The physiological relevance of this cleavage event remains unclear, although it is thought to inhibit activation of RIPK3 and necroptosis8. Here we show that the heterozygous missense mutations D324N, D324H and D324Y prevent caspase cleavage of RIPK1 in humans and result in an early-onset periodic fever syndrome and severe intermittent lymphadenopathy-a condition we term '  cleavage-resistant RIPK1-induced autoinflammatory syndrome'  . To define the mechanism for this disease, we generated a cleavage-resistant Ripk1(D325A) mutant mouse strain. Whereas Ripk1(-/-) mice died postnatally from systemic inflammation, Ripk1(D325A/D325A) mice died during embryogenesis. Embryonic lethality was completely prevented by the combined loss of Casp8 and Ripk3, but not by loss of Ripk3 or Mlkl alone. Loss of RIPK1 kinase activity also prevented Ripk1(D325A/D325A) embryonic lethality, although the mice died before weaning from multi-organ inflammation in a RIPK3-dependent manner. Consistently, Ripk1(D325A/D325A) and Ripk1(D325A/+) cells were hypersensitive to RIPK3-dependent TNF-induced apoptosis and necroptosis. Heterozygous Ripk1(D325A/+) mice were viable and grossly normal, but were hyper-responsive to inflammatory stimuli in vivo. Our results demonstrate the importance of caspase-mediated RIPK1 cleavage during embryonic development and show that caspase cleavage of RIPK1 not only inhibits necroptosis but also maintains inflammatory homeostasis throughout life.